Myositis Ossificans Circumscripta Research Articles

Atraumatic myositis ossificans of mentalis muscle: A rare case report

Rationale: Atraumatic myositis ossificans circumscripta is a benign condition characterized by the aberrant formation of bone in extraskeletal soft tissues without a usual connection to trauma. Patient Concern: A female patient of around 17 years of age reported with the main complaint of pain and swelling over the chin area for 6 months with no history of trauma. Diagnosis: Clinical, radiographic, and histopathological examinations were performed and all signs and symptoms pointed to a diagnosis of Atraumatic Myositis Ossificans in the Mentalis muscle. Intervention: Surgical exploration of the area concerned was done under (L.A) local anesthesia with adrenaline (1:1,00,000), where the nodes were extracted from the lower surface of the Mentalis muscle. The wound was sutured back to its normal physiologic anatomy, and the patient then was advised of postoperative instructions. Results: The patient recovered with a good prognosis and returned to a normal routine with good functional capacity. Lessons Learned: The practitioner must consider Atraumatic Myositis ossificans as a viable diagnosis for painful soft tissue calcification when a history of trauma is not present.

Myositis ossificans circumscripta after surgery and radiotherapy and during sunitinib treatment: a case report

BackgroundMyositis ossificans circumscripta is a self-limiting, benign, ossifying lesion that can affect any type of soft tissue. It is most commonly found in muscles as a solitary lesion. A history of recent trauma has been reported in approximately 50% of cases. Clinically, MOC presents as a painful swelling, which rapidly increases in size. The pain and inflammatory symptoms spontaneously disappear after approximately 2–6 weeks, and the mass stabilizes or decreases. Radiologically, myositis ossificans circumscripta can be divided into two phases. The first is the acute phase, which is followed by the mature phase 2–6 weeks later. During the acute phase, the radiological aspect does not show any specific abnormality. In the mature phase, plain radiographs and computed tomography show blurred calcifications around a hypodense center. We describe here the first case of myositis ossificans circumscripta, with appropriate follow-up, occurring during sunitinib exposure.Case presentationWe report a case of myositis ossificans circumscripta in a 34-year-old man (ethnicity unknown) receiving sunitinib for metastatic alveolar soft part sarcoma of the left thigh after surgery and radiotherapy. Four months after the first dose of sunitinib, the patient experienced painful swelling in the surgical scar area. Magnetic resonance imaging showed diffuse and marked edema of the anterior compartment of the thigh, without nodular lesions circumscribing a central core, and without bone signal abnormality. The increased visibility of the intermuscular fascia and convergence of normal muscle fibers (black hole effect), without the displacement seen in tumors, were suggestive of myositis. Therefore, antiangiogenic treatment was discontinued, and the symptoms rapidly resolved within a few days. Three weeks after the discontinuation of sunitinib, the inflammatory findings completely disappeared. Two months after the diagnosis of myositis ossificans circumscripta, plain radiographs and computed tomography showed an extensive calcified mass measuring > 12 cm. The continuation of favorable clinical outcomes was confirmed.ConclusionsTo the best of our knowledge, this is the first case of myositis ossificans circumscripta with appropriate follow-up occurring during sunitinib exposure. Owing to multimodal treatment of sarcoma, we cannot rule out the radiotherapy and surgery causality.

Inverted horn myositis ossificans circumscripta in the pelvis and bilateral adductors: an unreported shape at an unusual site

ANZ Journal of SurgeryVolume 92, Issue 11 p. 3040-3041 IMAGES FOR SURGEONS Inverted horn myositis ossificans circumscripta in the pelvis and bilateral adductors: an unreported shape at an unusual site Satvik N. Pai MBBS, Satvik N. Pai MBBS orcid.org/0000-0002-3621-150X Department of Orthopaedic Surgery, Sri Ramachandra Institute of Higher Education and Research, Chennai, India Contribution: Conceptualization, ​Investigation, Methodology, Visualization, Writing - original draft, Writing - review & editingSearch for more papers by this authorMohan M. Kumar MBBS, MS (Ortho), DNB, Mohan M. Kumar MBBS, MS (Ortho), DNB Department of Orthopaedic Surgery, Sri Ramachandra Institute of Higher Education and Research, Chennai, India Contribution: ​Investigation, Methodology, Project administration, Supervision, Writing - review & editingSearch for more papers by this author Satvik N. Pai MBBS, Satvik N. Pai MBBS orcid.org/0000-0002-3621-150X Department of Orthopaedic Surgery, Sri Ramachandra Institute of Higher Education and Research, Chennai, India Contribution: Conceptualization, ​Investigation, Methodology, Visualization, Writing - original draft, Writing - review & editingSearch for more papers by this authorMohan M. Kumar MBBS, MS (Ortho), DNB, Mohan M. Kumar MBBS, MS (Ortho), DNB Department of Orthopaedic Surgery, Sri Ramachandra Institute of Higher Education and Research, Chennai, India Contribution: ​Investigation, Methodology, Project administration, Supervision, Writing - review & editingSearch for more papers by this author First published: 25 January 2022 https://doi.org/10.1111/ans.17502Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. Volume92, Issue11November 2022Pages 3040-3041 RelatedInformation

A case of myositis ossificans traumatica on one skeleton from Viminacium

The Roman city and military camp of Viminacium is situated between the villages of Stari Kostolac and Drmno, 12 kilometres north-east of Pozarevac, close to the confluence of the Mlava and the Danube. During its history, it became the biggest urban settlement and the capital of the province of Upper Moesia (Moesia Superior), later First Moesia (Moesia Prima). In one of the necropoles of Viminacium, Pecine, in grave No. 5785, skeletal remains of a juvenile male individual were discovered. The burial took place in Late Antiquity. Anthropological analyses revealed a fracture of the right femur followed by myositis ossificans traumatica. The trauma to the bone can damage the overlying muscle and, occasionally, the muscle tissue will respond to the trauma by producing bone directly in the muscle tissue itself. This condition is known as myositis ossificans traumafica (post-traumatic myositis ossificans or myositis ossificans circumscripta) and is most likely to occur in response to trauma in young male individuals, and in the femoral (the quadriceps muscles) or humeral region (brachium muscles).

Traumatic myositis ossificans circumscripta (MOC)

We report a case of a 29-year-old man who had been a victim of a public road accident. Four weeks later, the patient developed an isolated right thigh mass located...

Non-traumatic myositis ossificans circumscripta

SonographyVolume 4, Issue 2 p. 88-92 Case Report Non-traumatic myositis ossificans circumscripta Simon O'Brien, Corresponding Author Simon O'Brien simon.j.obrien@outlook.com PRP Diagnostic Imaging Maitland, New South Wales, Australia Correspondence: Simon O'Brien, PRP Diagnostic Imaging Maitland, 262 High Street, Maitland, NSW 2320, Australia. E-mail: simon.j.obrien@outlook.comSearch for more papers by this author Simon O'Brien, Corresponding Author Simon O'Brien simon.j.obrien@outlook.com PRP Diagnostic Imaging Maitland, New South Wales, Australia Correspondence: Simon O'Brien, PRP Diagnostic Imaging Maitland, 262 High Street, Maitland, NSW 2320, Australia. E-mail: simon.j.obrien@outlook.comSearch for more papers by this author First published: 02 March 2017 https://doi.org/10.1002/sono.12103Citations: 1 Funding: None. Conflict of interest: None. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume4, Issue2June 2017Pages 88-92 RelatedInformation

Myosite ossifiante circonscrite du muscle brachial chez le sportif de haut niveau. À propos d’un cas et revue de la littérature

The musculus brachialis myositis ossificans circumscripta (MOC) are usually found in children after elbow fractures treated with massages. We report the case of a 20-year-old professional rugby player who presented a severe functional impairement when he was practicing rugby after direct trauma on the right arm during a match. A large calcified hematoma of the musculus brachialis was identified on standard X-rays and was confirmed by sonography. Surgical resection was therefore requested and histological analysis confirmed the diagnosis of circumscribed myositis ossificans. An immobilization by sling was for 15days and associated to a non-steroidal anti-inflammatory treatment. The result after 1year was excellent: the patient has resumed rugby competition without discomfort and no recurrence of the ossification.

Non-traumatic myositis ossificans circumscripta: Adiagnosis trap.

Myositis ossificans circumscripta (MOC) is a benign condition of non-neoplastic heterotopic bone formation in the muscle or soft tissue. Trauma plays a role in the development of MOC, thus, non-traumatic MOC is very rare. Although MOC may occur anywhere in the body, the lesions are localized predominantly in the high-risk sites of injury, such as the thigh, buttock, and elbow. MOC can easily be mistaken for osteomyelitis or a malignant tumor, specifically osteosarcoma or soft-tissue sarcoma. We report a rare case of non-traumatic myositis ossificans circumscripta of thigh which appear clinically and radiologically as a malignant neoplasm. Despite its rarity, MOC should be contemplated in the differential diagnosis of malignant tumors.

Myositis Ossificans Circumscripta Occurring in the Subacromial Space with Severe Mechanical Blocking of the Shoulder Joint: A Case Report.

Myositis ossificans circumscripta (MOC) is a localized, self-limiting, reparative lesion comprising hypercellular fibrous tissue and bone1. An MOC developing without any antecedent trauma is referred to as a pseudomalignant osseous tumor2. These lesions have been found to occur in various sites of the human body, including the shoulder region3-22. To the best of our knowledge, there have been no previous reports of MOC or pseudomalignant osseous tumor developing in the subacromial space. We report a case of pseudomalignant osseous tumor occurring at the subacromial space adjacent to the rotator interval that exhibited mechanical blocking of the shoulder gliding mechanism. The patient was informed that data concerning the case would be submitted for publication, and he provided consent. A nineteen-year-old man developed rapidly progressive pain at rest and disability of motion in the left shoulder without any history of trauma. After one week of symptoms, he visited an orthopaedic clinic and was treated with nonsteroidal anti-inflammatory drugs. Although the pain at rest ceased at eight weeks after its onset, he was referred to our clinic because pain with motion accompanied by loss of motion of the left shoulder remained. A firm, round, lightly tender mass (2 cm in diameter) with no mobility was palpable in the deep tissue superolateral to the coracoid process. The active mobility of the left shoulder was severely restricted to 70° in elevation (140° on the right side), 5° in external rotation (90° on the right side), and T10 (the highest segment of spinal anatomy reached with the thumb) in internal rotation (T7 on the right side). Laboratory findings, including serum alkaline phosphatase, were within normal limits. Radiographs showed a calcified round mass at the superolateral aspect of the coracoid process (Fig. 1). Fig. 1 Radiograph taken eight weeks after …

Myositis Ossificans of the Left Medial Pterygoid Muscle: Case Report and Review of the Literature of Myositis Ossificans of Masticatory Muscles

Myositis ossificans is a disease that is characterized by nonneoplastic, heterotopic bone formation within a muscle. Myositis ossificans traumatica, also called myositis ossificans circumscripta, is a disease in which muscles are ossified presumably following acute trauma, burns, surgical manipulation, or repeated injury. It is often remitted after surgical excision though some patients have repeated recurrences. Myositis ossificans traumatica of masticatory muscles is not frequently reported in the literature, with the most common clinical finding being a progressive limitation of motion in the mandible. The aim of this article is to present and discuss a case of myositis ossificans traumatica of the left medial pterygoid muscle and to review the literature of myositis ossificans of the masticatory muscles.

Acute Inflammatory Myalgia: Think of Myositis Ossificans Circumscripta

Myositis ossificans circumscripta (MOC) is a form of heterotopic ossification in extraskeletal soft tissues that is benign, but may appear clinically and radiologically as a malignant neoplasm1. An 18-year-old woman had sudden pain in her left thigh with functional impairment, without trauma. Examination revealed an indurated mass on the upper third of the thigh. Laboratory analyses were normal except for a C-reactive protein level at 35 mg/l …

Myositis ossificans circumscripta in the psoas muscle with femoral neuropathy

Myositis ossificans circumscripta is a benign, self-limiting, ossifying soft-tissue mass that typically occurs in skeletal muscle of the extremities after trauma. Occurrence in the psoas muscle is rare with no reports of this condition presenting as femoral neuropathy. A 54-year-old woman visited our hospital because of progressive left leg pain and weakness, which she had experienced for 2 years. Physical examination indicated left femoral neuropathy, and a 6 cm × 5 cm mass was palpable in the left groin. Plain radiographs showed an irregular calcification over the left hip. Computed tomography of the pelvis showed a fusiform mass within the left psoas muscle. A modified ilioinguinal approach was used to excise the mass, and histologic examination confirmed the diagnosis. After surgery, the patient's symptoms resolved and there was no recurrence at 4 years' follow-up. Excision may be considered when a patient has a large, painful mass with neuropathy and significant functional impairment after conservative treatment.

Myositis ossificans circumscripta of the triceps muscle in a Rottweiler dog

A 20-month-old male Rottweiler dog was presented with the complaint of chronic right forelimb lameness that was unresponsive to conservative treatment. Physical examination allowed for the topographical identification of the source of the problem as a firm enlargement of the soft tissues that was partially movable from humeral bone and compatible with an alteration of the triceps brachii muscle. Radiographic images showed signs that were highly suggestive of myositis ossificans. Computed tomography allowed for a more accurate characterization of the lesion, to exclude involvement of the elbow joint and humeral bone, and to localize anatomically the lesion in the caput accessorium and longum of the triceps brachii muscle. Surgical excision of the ossified portion of the triceps muscle was performed. Histological examination of the excised tissue substantiated the diagnosis of myositis ossificans. A one year clinical and radiographic follow-up examination showed a complete recovery, with no evidence of complications or recurrence. Despite myositis ossificans in dogs having previously been identified in the hindlimbs, this case of myositis ossificans circumscripta of the triceps muscle suggests that it may also occur in the muscles of the forelimb.

Myositis ossificans circumscripta of the triceps due to overuse in a female swimmer

Myositis ossificans is a rare condition characterized by non-neoplastic heterotopic bone formation in soft tissue and skeletal muscle. It is a benign and often self-limiting disease with no need for surgery. Here, we describe a young female swimmer with myositis ossificans circumscripta of the triceps due to overuse. Because of the benign character of the lesion, conservative treatment was initiated with rest and anti-inflammatory drugs. She obtained complete resolution after 6 months and was able to return to normal sporting activities. Myositis ossificans circumscripta is a rare benign lesion with an excellent prognosis. Most lesions in athletes occur due to contusions or strains; however, overuse is now described as well. Spontaneous resolution is seen in almost all cases. Cases in which, despite conservative treatment, a painful mass persists, surgical excision can be considered.

Precervical myositis ossificans in an infant secondary to child abuse

We present a 10-week-old girl with myositis ossificans circumscripta (MO) of the neck secondary to nonaccidental trauma. This condition is rarely seen in infants; furthermore, the majority of MO lesions develop in the extremities rather than the head and neck region. We will detail the US-guided biopsy technique used in our case, in addition to discussing the characteristic imaging and pathological findings of MO to assist in the diagnosis and successful treatment of this condition.

Diagnosis of Soft-Tissue Masses

AJR 2011; 197:W365 0361–803X/11/1972–W365 © American Roentgen Ray Society Diagnosis of Soft-Tissue Masses We read with great interest the article by Subhawong et al. [1], “Soft-Tissue Masses and Masslike Conditions: What Does CT Add to Diagnosis and Management?” in the June 2010 issue of the AJR. As stated in the article, CT in combination with MRI is particularly useful for the evaluation of soft-tissue masses. In fact, CT may allow the detection of tiny calcifications as a key element in the early diagnosis of some soft-tissue masses, including myositis ossificans circumscripta (MOC) or paraosteoarthropathy (POA). However, it is noteworthy that sonography may allow the detection of the onset of mineralization before calcifications appear on radiographs or CT scans. Indeed, sonography is actually the most sensitive imaging modality for early diagnosis of the MOC zone phenomenon, in which a thin annular hyperechoic zone corresponds to the calcification area [2] (Fig. 1). Similarly, early sonographic assessment of patients with local signs of inflammation suggesting initial POA formation may permit a prompt and confident diagnosis as well [3] (Fig. 2). In both cases, hyperhemia can be observed contiguously on Doppler sonography. Using sonography for diagnosis may thus improve patient management: Nonsteroidal antiinflammatory agent therapy may stop the evolutionary process of POAs and MOC and prevent further heterotopic bone production [4]. Biopsy performance in acute and subacute MOC phases can yield falsepositive results in favor of malignancy owing to the malignant soft-tissue-like aspect at that time [5]. Because earlier diagnosis may permit earlier and more effective treatment and avoid useless biopsy, we think that sonography should be used as a first-choice diagnostic step in combination with MRI and CT to diagnose such soft-tissue masses. Alexis Lacout Centre d’Imagerie Medicale Centre Medico Chirugical (CMC)– groupe VITALIA Aurillac, France Pierre-Yves Marcy Antoine Lacassagne Cancer Research Institute Nice, France Robert Yves Carlier Hopital Raymond Poincare Service d’Imagerie Medicale Universite Paris Ile-de-France Ouest Garches, France DOI:10.2214/AJR.10.5203 WEB—This is a Web exclusive article.

Benign calcifying fibrous-myofibroblastic tumor mimicking myositis ossificans in a 22-month-old girl

Myositis ossificans circumscripta (MOC), with nonneoplastic heterotopic bone formation in soft tissue and skeletal muscle, is rare in children. Extraskeletal osteosarcoma is a very rare malignant mesenchymal neoplasm of soft tissues in children. At onset, it may be difficult to distinguish MOC from a musculoskeletal infection or neoplasm, particularly in the absence of trauma, and a biopsy is frequently required. However, differentiating MOC from malignant neoplasm is imperative. We describe the case of a 22-month-old girl who presented with a benign fibrous-myofibroblastic tumor mimicking MOC. However, extraskeletal osteosarcoma was also considered in the differential diagnosis due to the absence of attachment of the lesion to the skeleton. Pathologic findings after a previous needle biopsy and posterior marginal resection exclude both differential diagnoses. Close follow-up during 3 years postoperatively showed no signs of recurrence.

Noninfectious painful neck mass mimicking malignancy in a child

A large painful mass on the posterior neck of a child of a relatively short duration is uncommon. Barring infectious origin, differential diagnosis can be difficult without a definitive biopsy. A 12-year-old girl had a markedly painful posterior neck mass and limitation of neck motion without fever for 1 month. The rapid clinical course and poorly defined marginal zone of the CT images led to suspicion of malignancy. Although the initial frozen section suggested low-grade fibrosarcoma, a successful wide excision and paraffin pathology confirmed the diagnosis of myositis ossificans circumscripta (MOC) from the semispinalis capitis muscle. The occurrence of MOC in children is rare and may easily be misdiagnosed as soft tissue sarcoma. Both knowledge of the disease and guidelines for taking an aggressive biopsy sample are essential for correct diagnosis and appropriate treatment.

FDG PET/CT Findings in a Case of Myositis Ossificans Circumscripta of the Forearm

Myositis ossificans circumscripta (MOC) is a rare benign neoplasm located in soft tissues that, most of the time, appears after a local trauma. The positive diagnosis of MOC may be challenging on CT or MRI findings. We report on an atypical case of a spontaneous nontraumatic MOC in a 54-year-old man, located in the longus supinatus muscle diagnosed with MRI and F-18 FDG PET/CT findings. Rarely described F-18 FDG PET/CT features in MOC are presented. Pattern of avid FDG focus on PET/CT, that may wrongly suggest osteosarcoma, is presented.

Myositis Ossificans Circumscripta Without History of Trauma

Myositis ossificans circumscripta is a form of heterotopic ossification that is benign in nature associated to a trauma, but may appear clinically and radiologically as a malignant neoplasm. We describe a rare case of calcifying of myositis ossificans not associated to trauma in a 35-year-old woman with a mass in her upper third and external of right thigh. We discuss some of the difficulties of diagnosis and histological evolution of the lesion.KeywordsMyositis ossificans; Thigh; Differential diagnosis; Nontraumatic