Purpose: estimation of the dynamics of distribution of the organism water environment in patients with acute coronary syndrome (ACS) taking into account the presence of myocardial hypertrophy of left ventricle, at different stages of hospitalization. Materials and methods: we have examined 120 patients with ACS undergoing restoration of coronary blood flow. The assessment was made traditional and renal risk factors (albuminuria 30-300 mg/l, the value of eGFR), and produced the aqueous environments of the body. All examined patients were divided into two groups. The first group includes patients with left ventricular hypertrophy, the second group included patients without hypertrophy of the LV myocardium. Results: for both studied groups were characterized by the increase in the total water volume (TWV), the total liquid volume (TLV), the intracellular fluid volume (IFV) at all stages of the study. Summary: in patients with ACS and the presence of LV hypertrophy found a significant increase of the average content of TWV, TLV, IFV at all stages of hospitalization. Also in the group of patients with LV remodeling and hyperhydratation was observed a decrease in GFR, and the presence of albuminuria.