Mycoplasma Pneumonia In Children Research Articles

Mycoplasma pneumoniae detections in children with lower respiratory infection before and during the COVID-19 pandemic: a large sample study in China from 2019 to 2022

BackgroundNonpharmaceutical interventions (NPIs) implemented to reduce the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have suppressed the spread of other respiratory viruses during the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to explore the epidemiological trends and clinical characteristics of Mycoplasma pneumoniae (MP) infection among inpatient children with lower respiratory tract infection (LRTI) before and during the COVID-19 pandemic, and investigate the long-term effects of China’s NPIs against COVID-19 on the epidemiology of MP among inpatient children with LRTI.MethodsChildren hospitalised for LRTI at the Department of Pulmonology, The Children’s Hospital, Zhejiang University School of Medicine (Hangzhou, China) between January 2019 and December 2022 were tested for common respiratory pathogens, including Mycoplasma pneumoniae (MP), Chlamydia trachomatis (CT) and other bacteria. Clinical data on age, sex, season of onset, disease spectrum, and combined infection in children with MP-induced LRTI in the past 4 years were collected and analysed.ResultsOverall, 15909 patients were enrolled, and MP-positive cases were 1971 (34.0%), 73 (2.4%), 176 (5.8%), and 952 (20.6%) in 2019, 2020, 2021, and 2022, respectively, with a significant statistical difference in the MP-positive rate over the 4 years (p <0.001). The median age of these children was preschool age (3–6 years), except for 2022, when they were school age (7–12 years), with statistical differences. Comparing the positive rates of different age groups, the school-age children (7–12 years) had the highest positive rate, followed by the preschoolers (3–6 years) in each of the 4 years. Compared among different seasons, the positive rate of MP in children with LRTI was higher in summer and autumn, whereas in 2020, it was highest in spring. The monthly positive rate peaked in July 2019, remained low from 2020 to 2021, and rebounded until 2022. Regarding the disease spectrum, severe pneumonia accounted for the highest proportion (46.3%) pre-pandemic and lowest (0%) in 2020.ConclusionTrends in MP detection in children with LRTIs suggest a possible correlation between COVID-19 NPIs and significantly reduced detection rates. The positivity rate of MP gradually rose after 2 years. The epidemic season showed some differences, but school-age children were more susceptible to MP before and during the COVID-19 pandemic.

Identification of mycoplasma pneumonia in children based on fusion of multi-modal clinical free-text description and structured test data.

Mycoplasma pneumonia may lead to hospitalizations and pose life-threatening risks in children. The automated identification of mycoplasma pneumonia from electronic medical records holds significant potential for improving the efficiency of hospital resource allocation. In this study, we proposed a novel method for identifying mycoplasma pneumonia by integrating multi-modal features derived from both free-text descriptions and structured test data in electronic medical records. Our approach begins with the extraction of free-text and structured data from clinical records through a systematic preprocessing pipeline. Subsequently, we employ a pre-trained transformer language model to extract features from the free-text, while multiple additive regression trees are used to transform features from the structured data. An attention-based fusion mechanism is then applied to integrate these multi-modal features for effective classification. We validated our method using clinic records of 7157 patients, retrospectively collected for training and testing purposes. The experimental results demonstrate that our proposed multi-modal fusion approach achieves significant improvements over other methods across four key performance metrics.

Pediatric Mycoplasma Pneumonia: The Radiographic Patterns and Review of the Literature.

The purpose of the present paper was to evaluate the clinical and chest radiographic features of pediatric patients with serologically proven Mycoplasma pneumoniae pneumonia. The clinical records and chest radiographs of 55 consecutive patients (28 male, 27 female) with serologically positive IgG mycoplasma pneumonia were reviewed. The pneumonic infiltrates were described on chest radiography into 3 different patterns as a peribronchovascular infiltration, reticulonodular infiltration and consolidation. More than 91% of patients presented with cough and 70% of patients had fever. Chest radiographs displayed three different patterns: (i) peribronchovascular infiltration (n=33, 60%); (ii) reticulonodular infiltration (n=12, 22%); (iii) consolidation (n=10, 18%). Bilateral peribronchovascular infiltration in central and middle lung zones were frequently seen (n=33, 60%). Other radiological features were unilateral lesions in 51% of patients, pleural effusion in 18%, and hilar lymphadenopathy in 20%. There are various radiological features of mycoplasma pneumonia in children. Bilateral peribronchovascular infiltration confined to central and middle lung regions seems to be more closely associated with mycoplasma infection.

The Effect of Azithromycin in Treating Mycoplasma Pneumonia in Children

Objective: To discuss and analyze the effect of azithromycin in the treatment of mycoplasma pneumonia in children. Methods: A total of 120 children with mycoplasma pneumonia who were admitted to the Department of Pediatrics of our hospital from January 2022 to December 2022 were selected as the research subjects. They were divided into an azithromycin group and a reference group according to the random number drawing method, with 60 cases in each group. The azithromycin group was treated with azithromycin, and the reference group was treated with conventional treatment. The efficacy of treatment, laboratory indicators, platelet count and D-dimer, and adverse reactions of both groups were compared. Results: The efficacy of the azithromycin group was significantly higher than that of the reference group (P &lt; 0.05). Before treatment, there were no significant differences in the laboratory indicators like ferritin, procalcitonin (PCT), and erythrocyte sedimentation rate (ESR) between the two groups (P &gt; 0.05); after treatment, the laboratory indicators of the azithromycin group were significantly better than those of the reference group (P &lt; 0.05). Before treatment, there was no statistically significant difference in platelet count and D-dimer between the groups (P &gt; 0.05); after medication, the platelet count, and D-dimer in the azithromycin group were significantly better than those in the reference group (P &lt; 0.05). The total incidence of adverse reactions in the azithromycin group was significantly lower than that in the reference group (P &lt; 0.05). Conclusion: Azithromycin is more effective in treating mycoplasma pneumonia in children, and has certain clinical value.

Predictive value of chemokines (CCL 2) in bronchoalveolar lavage fluid for refractory mycoplasma pneumonia in children

BackgroundThere are relatively few studies investigating C-C motif chemokine ligand 2 (CCL2) level in bronchoalveolar lavage fluid (BALF) in children with Mycoplasma pneumoniae pneumonia (MPP), and the relationship between CCL2 level in BALF and refractory mycoplasma pneumoniae pneumonia (RMPP) is unclear. This study aims to explore the relationship between chemokine CCL2 level in BALF and clinical characteristics and clinical outcome in children with MPP.MethodsA total of 51 children with confirmed acute MPP and requiring bronchoalveolar lavage in Department of Pediatrics, Huanghe Sanmenxia Hospital and The First Clinical College of Xinxiang Medical University from October 2021 to February 2023 were selected as the study group. And 11 children with bronchial foreign body were selected as the control group. The study group was divided into the non-refractory mycoplasma pneumoniae pneumonia (NRMPP) group and the RMPP group based on the response to treatment. BALF and clinical data of the patients were collected. And CCL2 levels were tested in the patients. Differences in CCL2 level in BALF and clinical characteristics were tested and compared.ResultsThe CCL2 level in BALF of the study group was higher than that of the control group, with significant difference (P < 0.05). With ROC curve, the area under the curve (AUC) of CCL2 in BALF predicting RMPP was 0.94, the cut-off value was 0.645 ng/ml, the sensitivity was 85%, and the specificity was 94%, and the diagnostic value was better than that of serum CRP and LDH. Logistic regression analysis was used to build the RMPP prediction model, and CCL2 showed good predictive value.ConclusionThe level of CCL2 in BALF was high in children with MPP and had a high predictive value for RMPP. CCL2 can be used as one of the biomarkers for predicting RMPP.

Retracted: Effect Evaluation of Artificial Intelligence-Based Electronic Health PDCA Nursing Model in the Treatment of Mycoplasma Pneumonia in Children.

[This retracts the article DOI: 10.1155/2022/1956944.].

Clinical characteristics and serum inflammatory markers of community-acquired mycoplasma pneumonia in children.

To compare the demographic and clinical features, laboratory and imaging findings in mycoplasma pneumoniae pneumonia (MPP) children with non-MPP (NMPP) children and general MPP (GMPP) children with refractory MPP (RMPP) children and analysis the relationship with the severity of disease. The study included 265 children with MPP and 230 children with NMPP in the Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University from 2020 to 2021. The children with MPP included RMPP (n = 85) and GMPP (n = 180). Demographic and clinical characteristics, laboratory and imaging findings of all children were measured as baseline data within 24 h after admission and the differences between MPP and NMPP, RMPP and GMPP patients were compared. ROC curves were used to evaluate the diagnostic and predictive value of different indicators for RMPP. Fever duration and hospital stay in children with MPP were longer than those with NMPP. The number of patients with imaging features of pleural effusion, lung consolidation and bronchopneumonia in MPP group was significantly higher than that in NMPP group. Compared with NMPP group, the levels of C-reactive protein (CRP), procalcitonin (PCT), serum amyloid A (SAA), erythrocyte sedimentation rate (ESR), lactic dehydrogenase (LDH), prothrombin time (PT), fibrinogen (FIB) and D-dimer and inflammatory cytokines (interleukin [IL]-6, IL-8, IL-10 and IL-1β) in MPP group were significantly higher (P < 0.05). The clinical symptoms and pulmonary imaging findings were more severe in RMPP group. The levels of white blood cell (WBC), CRP, PCT, SAA, ESR, alanine aminotransferase (ALT), LDH, ferritin, PT, FIB, D-dimer and inflammatory cytokines in RMPP group were higher than those in GMPP group. There was no significant difference in the level of lymphocyte subsets between the RMPP and GMPP group. IL-6, IL-10, LDH, PT, D-dimer and lung consolidation were independent risk factors for RMPP. IL-6 levels and LDH activity were good predictors of RMPP. In conclusion, there were differences in clinical characteristics and serum inflammatory markers between MPP group and NMPP group, RMPP group and GMPP group. IL-6, IL-10, LDH, PT and D-dimer can be used as predictive indicators for RMPP.

Reduced serum 25(OH)D is closely related to bronchial mucus plug formation in children with mycoplasma pneumonia: A prospective cohort study.

The relationship between vitamin D nutritional status and the formation of bronchial mucus plugs (BMPs) is unclear. The aims of the current study were to investigate associations between serum 25(OH)D levels, serum inflammatory factors, and clinical characteristics in children with mycoplasma pneumonia (MPP), and to summarize the risk factors for BMPs in children with MPP. Clinical data from 175 children with MPP were collected and analyzed, the children were divided into a BMP group and a non-BMP group. Serum 25(OH)D levels, IL-8, and various inflammatory factors were compared in the two groups. Associations between 25(OH)D levels and IL-8, various inflammatory factors, and clinical characteristics were analyzed, and the diagnostic value of serum 25(OH)D levels was assessed. Serum 25(OH)D level was significantly lower in the BMP group (p < 0.05). Serum IL-8 level, percentages of neutrophils, and some inflammatory factors were significantly higher in the BMP group (p < 0.05). Serum 25(OH)D level was negatively correlated with IL-8, neutrophil percentage, various inflammatory factors (all p < 0.05). It was also associated with lobular infection, pleural effusion, mechanical ventilation, and mycoplasma 2,063/2,064 mutation (all p < 0.05). In multivariate regression analysis 25(OH)D [odds ratio (OR) 0.98, 95% confidence interval (CI) 0.97-0.99, p = 0.003], IL-8 (OR 1.02, 95% CI 1.00-1.04, p = 0.002), polylobular infection (OR 1.75, 95% CI 1.17-2.64, p = 0.007), and MP DNA copies (OR 0.98, 95% CI 1.04-1.01, p = 0.022) were independent risk factors for BMPs, and the area under the curve value was 0.915 (95% CI 0.895-0.935). If the serum 25(OH)D level was <50 nmol/L, the respective percentages for sensitivity, specificity, positive predictive value, and negative predictive value were 97, 81, 78.9, and 97.6%. Vitamin D deficiency is common in children with MPP, and 25(OH)D levels are closely associated with inflammatory factors and disease severity in children. The serum 25 (OH) D level of MPP children with BMPs was lower than that of children without BMPs. Serum 25(OH)D can be used as a marker for the diagnosis of MPP in children with BMPs.

Clinical observation of Tanreqing combined with azithromycin in sequential treatment of mycoplasma pneumonia in children.

article: Clinical observation of Tanreqing combined with azithromycin in sequential treatment of mycoplasma pneumonia in children - Minerva Pediatrics 2023 February;75(1):161-3 - Minerva Medica - Journals

Combined diagnostic potential of multi-slice spiral CT and serum CRP levels in children with Mycoplasma pneumonia after azithromycin treatment

Purpose: To investigate the combined diagnostic value of multi-slice spiral computerized tomography (MSCT) and serum C-reactive protein (CRP) levels in children with mycoplasma pneumonia (MPP) after azithromycin treatment.Methods: Clinical data for 60 children with MPP who were treated in The First People's Hospital of Chenzhou, Chenzhou from February 2019 to February 2020, were retrospectively analyzed. All children were treated with azithromycin. Serum CRP levels were measured using immunoturbidimetric endpoint assay, while MSCT examination was done before and after treatment. This was a self-control clinical study in which the 60 patients served as their own controls. Thus, results obtained before treatment (control group, CG) were compared with those obtained after treatment (study group, EG). Within the same period, 60 healthy subjects were selected as the healthy group (HG), and were subjected to MSCT examination and serum CRP assay. The diagnostic results of CT were analyzed, and the responsiveness, selectivity, and positive and negative predictive values of the combination of MSCT and serum CRP levels were calculated.Results: Pre-treatment serum CRP level was higher in CG than in EG and HG, and CRP level was higher in EG than in HG (p &lt; 0.001). The MSCT imaging features of EG were significantly different from those of CG (p &lt; 0.05). The probabilities of bronchial wall thickening, hilar and mediastinal lymphadenopathy and pleural effusion were significantly higher in CG than in EG (p &lt; 0.05). The responsiveness, selectivity, and positive and negative predictive values of combination of MSCT and serum CRP in MPP children after azithromycin treatment were 70.0, 66.7, 67.7 and 69.0 %, respectively.Conclusion: The combination of MSCT examination and serum CRP levels resulted in high diagnostic efficiency, and it may be useful for monitoring MPP in children after azithromycin treatment. Therefore, the combined procedure may reduce the burden on families of MPP children by enhancing efficiency of diagnosis of the disease.

Evaluation of Curative Effect and TNF-�� Level of Refractory Mycoplasma Pneumonia in Children Treated with Methylprednisolone and Azithromycin

Evaluation of Curative Effect and TNF-�� Level of Refractory Mycoplasma Pneumonia in Children Treated with Methylprednisolone and Azithromycin

Application Value of Detection of Mycoplasma Pneumoniae RNA and MP-DNA Load in Early Diagnosis of Refractory Mycoplasma Pneumonia in Children

Application Value of Detection of Mycoplasma Pneumoniae RNA and MP-DNA Load in Early Diagnosis of Refractory Mycoplasma Pneumonia in Children

Refractory Mycoplasma Pneumonia in Children: A Systematic Review and Meta-analysis of Laboratory Features and Predictors.

Background Mycoplasma pneumoniae is a common pathogen of community-acquired pneumonia (CAP) in children. M. pneumoniae infection is usually regarded as a self-limiting disease, but in some special cases, it can also develop into refractory Mycoplasma pneumoniae pneumonia (RMPP). The aim of this study is to analyze the clinical characteristics of CRP (C-reactive protein), LDH (lactate dehydrogenase), ESR (erythrocyte sedimentation rate), D-dimer, neutrophils (%), lymphocytes (%), and lung consolidation in RMPP and explore their prediction results in the early stage of RMPP, which is important for early treatment. Methods This systematic search was conducted in PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wangfang, and Cqvip, and the date was set until February 23, 2021. For the continuous variables, mean difference (MD) with 95% CI was adopted to evaluate CRP, LDH, ESR, D-dimer, neutrophils (%), lymphocytes (%), and the correlation between lung consolidation and RMPP. Results 20 studies including 5289 patients were included in the analysis, and the results showed that the CRP of the RMPP group (MD (95% CI): 22.29 (12.20, 32.38), P < 0.001), LDH (MD (95% CI): 145.13 (78.62, 211.64), P < 0.001), neutrophils (%) (MD (95% CI): 7.27 (0.31, 14.23), P = 0.04), and D-dimer (MD (95% CI): 1.79 (-1.17, 4.74), P = 0.24) was higher than that of the NRMPP group; the risk of lung consolidation in the RMPP group (OR (95% CI): 14.29 (4.52, 45.12), P < 0.001) was higher than that in the NRMPP group, and there was no difference in ESR (MD (95% CI): 8.11 (-1.34, 17.56), P = 0.09) and lymphocytes (%) (MD (95% CI): -6.27 (-12.81, 0.27), P = 0.06) between the two groups. Conclusion So, the available evidence indicates that CRP, LDH, neutrophils (%), D-dimer, and lung consolidation are predictive factors for RMPP.

Effect of Glucocorticoid on Refractory Mycoplasma Pneumonia in Children and Its Influence on Lung Function

Effect of Glucocorticoid on Refractory Mycoplasma Pneumonia in Children and Its Influence on Lung Function

Analysis of Clinical Value of Methylprednisolone Combined with Azithromycin in the Treatment of Refractory Mycoplasma Pneumonia in Children

Analysis of Clinical Value of Methylprednisolone Combined with Azithromycin in the Treatment of Refractory Mycoplasma Pneumonia in Children

Effect Evaluation of Artificial Intelligence-Based Electronic Health PDCA Nursing Model in the Treatment of Mycoplasma Pneumonia in Children.

The PDCA cycle, also known as Deming's cycle, mainly includes four stages: planning, implementation, inspection, and processing. As a kind of atypical pneumonia with fever and cough, mycoplasma pneumonia harms the health of many children. The purpose of this study is to investigate the anti-inflammatory and antimycoplasma effects and safety of artificial intelligence e-health PDCA nursing mode on pediatric MPP, to investigate its clinical efficacy, to observe the changes of serum cytokines (IL-10, IL-2, IL-4, IFN-γ), and to explore the mechanism of action and possible targets for the treatment of MPP, to provide a new basis for clinical treatment of MPP. The experimental results show that in the experimental group using PDCA nursing mode, the total satisfaction is 97.22%, higher than the control group of 94.44%; in the experimental group, the hospital stay and symptom disappearance time were significantly shortened by four hours. The satisfaction of nursing staff was significantly increased in statistical significance (P < 0.05). Therefore, in a statistical sense, the artificial intelligence e-health PDCA nursing mode can significantly improve the clinical symptoms of MPP children with wind-heat stagnation of lung syndrome and phlegm-heat closure of lung syndrome, improve the treatment effect of childhood mycoplasma pneumonia epidemic, shorten the time of hospitalization and symptom disappeared, and play a great auxiliary role in the treatment of childhood mycoplasma pneumonia.

Analysis of Clinical Efficacy of Erythromycin Combined with Oseltamivir Phosphate Granules in the Treatment of Mycoplasma Pneumonia in Children

We attempt to discuss the improvement of clinical efficacy of erythromycin combined with oseltamivir phosphate granules in children with mycoplasma pneumonia and its influence on lung function and infection indicators. We selected 60 patients with mycoplasma pneumonia in children from February 2019 to June 2020 and randomly divided them into observation group (30 cases of erythromycin combined with oseltamivir phosphate granules) and control group (oseltamivir phosphate) Wei granule treatment (30 cases), compare the clinical effective rate, changes in various indicators of lung function, disappearance time of clinical symptoms and changes in serum procalcitonin, C-reactive protein and interleukin 6 concentration levels in both groups before and after treatment. Observation group possessed remarkably higher ratio of time to peak tidal expiratory flow to total expiratory time, ratio of instantaneous velocity to tidal peak expiratory velocity at 75 % tidal volume and tidal volume than control group (p<0.05); and it had remarkably lower antipyretic time, rales disappearance time, throat and tonsil hyperemia disappearance time than control group (p<0.05); observation group possessed remarkably lower length of stay than control group (p<0.05) and procalcitonin, interleukin 6 and C-reactive protein concentration in serum of observation group declined more than control group (p<0.05). The total clinical effective rate of observation group (93.4 %) was remarkably higher than control group (80 %) (p<0.05). Erythromycin combined with oseltamivir phosphate particles can remarkably improve the clinical effectiveness of mycoplasma pneumonia in children, improve lung signs and clinical effectiveness and reduce procalcitonin, C-reactive protein and interleukin 6 concentration in serum. Effective treatment of pneumonia provides clinical guidance value.

Network Meta-analysis of 14 oral Chinese patent medicines combined with Azithromycin in treatment of mycoplasma pneumonia in children

To systematically evaluate the clinical efficacy of 14 oral Chinese patent medicines combined with Azithromycin in the treatment of mycoplasma pneumonia in children with network Meta-analysis. Computer retrieval was performed for such databases as CNKI, VIP, Wanfang, CBM, PubMed, EMbase and Cochrane Library to screen out randomized controlled trials of oral Chinese patent medicines combined with Azithromycin in the treatment of mycoplasma pneumonia in children from the time of database establishment to September 2020. The included studies were evaluated by the Cochrane Risk Assessment tool. Stata 14.0 and Review Manager 5.3 software were used for data statistical analysis. A total of 60 RCTs were included in this study, involving 14 oral Chinese patent medicines. The efficacy ranking based on network Meta-analysis was as follows:(1)in terms of total effective rate, top five Chinese patent medicines in surface under the cumulative ranking curve(SUCRA) were Xiao'er Xiaoji Zhike Oral Liquid, Xiao'er Chiqiao Qingre Granules, Xiao'er Feike Granules, Pudilan Xiaoyan Oral Liquid and Lanqin Oral Liquid;(2)in terms of antifebrile time, top five Chinese patent medicines in SUCRA were Huaiqihuang Granules, Xiao'er Magan Granules, Xiao'er Kechuanling Granules/Oral Liquid, Shuanghuang-lian Oral Liquid for children and Xiao'er Xiaoji Zhike Oral Liquid;(3)in terms of cough disappearance time, top five Chinese patent medicines in SUCRA were Xiao'er Magan Granules, Huaiqihuang Granules, Xiao'er Chiqiao Qingre Granules, Xiao'er Feire Kechuan Oral Liquid and Xiao'er Kechuanling Granules/Oral Liquid;(4)in terms of rale disappearance time, top five Chinese patent medicines in SUCRA were Xiao'er Magan Granules, Huaiqihuang Granules, Xiao'er Feire Kechuan Oral Liquid, Shuanghuanglian Oral Liquid for children and Yupingfeng Granules. The results showed that on the basis of the use of Azithromycin, combined administration with oral Chinese patent medicines could improve the overall clinical efficacy in the treatment of mycoplasma pneumonia in children. However, due to the large differences in the quality and the number of included studies among various therapeutic measures, the ranking results of SUCRA of Chinese patent medicines need to be verified by high-quality multi-center, large-sample, randomized double-blind trials in the future.

Computed Tomography Image Texture under Feature Extraction Algorithm in the Diagnosis of Effect of Specific Nursing Intervention on Mycoplasma Pneumonia in Children.

To evaluate the effect of specific nursing intervention in children with mycoplasma pneumonia (MP), a feature extraction algorithm based on gray level co-occurrence matrix (GLCM) was proposed and combined with computed tomography (CT) image texture features. Then, 98 children with MP were rolled into the observation group with 49 cases (specific nursing) and the control group with 49 cases (routine nursing). CT images based on feature extraction algorithm of optimized GLCM were used to examine the children before and after nursing intervention, and the recovery of the two groups of children was discussed. The results showed that the proportion of lung texture increase, rope shadow, ground glass shadow, atelectasis, and pleural effusion in the observation group (24.11%, 3.86%, 8.53%, 15.03%, and 3.74%) was significantly lower than that in the control group (28.53%, 10.23%, 13.34%, 21.15%, and 8.13%) after nursing (P < 0.05). There were no significant differences in the proportion of small patchy shadows, large patchy consolidation shadows, and bronchiectasis between the observation group and the control group (P > 0.05). In the course of nursing intervention, in the observation group, the disappearance time of cough, normal temperature, disappearance time of lung rales, and absorption time of lung shadow (2.15 ± 0.86 days, 4.81 ± 1.14 days, 3.64 ± 0.55 days, and 5.96 ± 0.62 days) were significantly shorter than those in the control group (2.87 ± 0.95 days, 3.95 ± 1.06 days, 4.51 ± 1.02 days, and 8.14 ± 1.35 days) (P < 0.05). After nursing intervention, the proportion of satisfaction and total satisfaction in the experimental group (67.08% and 28.66%) was significantly higher than that in the control group (40.21% and 47.39%), while the proportion of dissatisfaction (4.26%) was significantly lower than that in the control group (12.4%) (P < 0.05). To sum up, specific nursing intervention was more beneficial to improve the progress of characterization recovery and the overall recovery effect of children with MP relative to conventional nursing. CT image based on feature extraction algorithm of optimized GLCM was of good adoption value in the diagnosis and treatment of MP in children.

Application value of erythromycin combined with azithromycin sequential therapy in the treatment of mycoplasma pneumonia in children.

article: Application value of erythromycin combined with azithromycin sequential therapy in the treatment of mycoplasma pneumonia in children - Minerva Pediatrics 2021 Jul 15 - Minerva Medica - Journals