This paper examines the current state of the Enterprise Marketing Ecosystem (EME), especially in the context of Digital Transformation (DT), highlighting both the challenges and opportunities it presents. A significant focus is placed on the potential of genetic algorithms to address the complex optimization problems inherent in this transformation. The core issues faced by enterprises in their digital marketing evolution are elaborated, setting the stage for the exploration of genetic algorithms in this domain. The research delves into the specific steps of the proposed method, utilizing the multi-objective genetic algorithm NSGA-II to optimize various aspects of market strategies. The methodology includes the generation of an initial population, evaluation of fitness according to the tailored needs of the marketing ecosystem, selection, crossover, and mutation operations, followed by the formation of a new generation of solutions. The termination criteria of the algorithm are also discussed. Experimental results are presented, demonstrating the effectiveness of the genetic algorithm in enhancing the DT of the EME. Comparisons with traditional approaches reveal significant improvements in various key performance metrics, underscoring the algorithm’s capability in navigating the complexities of digital marketing optimization.