Mutagenicity Of Pesticides Research Articles

Hygiene in supporting scientific and technological development of the country and sanitary and epidemiological welfare of the population (to the 130th anniversary of the Federal Scientific Centre of Hygiene named after F.F. Erisman)

Introduction. Historical analysis is extremely important in assessing the development and achievements of scientific schools and scientific centres. This is especially true concerning research centres operated continuously from the end of the 19th century to almost the first quarter of the 21st century, which include the Federal Scientific Center for Hygiene (FSCH), named after F.F. Erisman of the Federal Service for Supervision of Consumer Rights Protection and Human Wellbeing. The purpose of the study is to analyze the results, achievements and prospects for further development of the FSCH as the head multidisciplinary scientific institution of the Federal Service for Supervision of Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor). Materials and methods. Expert-analytical, historical research has been carried out. Analysis materials include the main results of the centre’s activities in the historical aspect, scientific achievements of the last quarter of a century, plans, directions for ensuring the scientific and technological development of the country in the field of hygiene and health protection, ensuring the sanitary and epidemiological wellbeing of the country’s population. Results. The main stages of the formation and development of the FSCH are associated with scientific and technological revolutions, technical progress, the development of all sectors of the national economy. The results of scientific research have made it possible to establish the nature and extent of the impact of environmental factors, industrial and educational environment on the health of various groups of the population. At the turn of the century, the FSCH got involved in nanomaterials and nanotechnologies hazard assessment. Fundamental studies of the FSCH made it possible to reveal the modern mechanisms of the formation of biocenoses of the environment of new innovative complexes with an assessment of the health risk, to establish the effect of the components of the formulations on the mutagenicity of pesticides. An assessment of the risk to the population due to the complex intake of pesticides into the body is also given. FSCH effectively participates in the implementation of national projects “Demography”, “Ecology”, “Clean Air”. Conclusion. FSCH contributed to the provision of scientific and technological development of the country and the sanitary and epidemiological wellbeing of various population groups. The development of the FSCH is associated with participation in the implementation of fundamental and exploratory research approved by order of the Government of the Russian Federation, sectoral research programs of Rospotrebnadzor, national projects “Demography”, “Ecology”, “Clean Air”, events of the Decade of Childhood (2018-2027).

農薬とその分解代謝物の突然変異原性について

農薬とその分解代謝物の突然変異原性について

Study on mutagenicity of pesticides in agricultural workers

Study on mutagenicity of pesticides in agricultural workers

MUTAGENICITY OF SOME COMMON PESTICIDES IN BARLEY

The perusual of literature reveals the desirability to screen the mutagenicity of pesticides. The present report deals with the cytological aberrations and chlorophyll mutations induced by Thiodan, Folithion, Lebaycid and Kitazin, employing barley as the test material. The chromosomal aberrations were examined both at mitotic and meiotic level. The root tip cells from pesticide treated barley grains revealed various abnormalities at metaphase including fragmentation, unequal chromosome, chromosomes with displaced satellite and increased number of chromosome. The laggards, bridges, tripolarity, tetrapolarity and micronuclei were seen at later stages. A positive correlation between dose and aberration was noticed. The meiotic analysis of PMC's from plants raised from pesticide treated barley grains, revealed quadrivalents and univalents at metaphase-I. Anaphase-I was atypical in having unequal distribution, laggards, bridges — single or double. The persistent bridges at telophase and micronuclei were not unfrequent. The pollen fertility was reduced. — M2 analysis at the seedling stage revealed albina, xantha and tigrina mutants. The tigrina's were more frequent. Lebaycid was the most effective while Thiodan was the most efficient.

A method to test plant metabolism on the mutagenicity of pesticides

A method to test plant metabolism on the mutagenicity of pesticides

Mutagenicity of pesticides evaluated by means of gene conversion in S. cerevisiae and A. nidulans

Mutagenicity of pesticides evaluated by means of gene conversion in S. cerevisiae and A. nidulans

Comparative investigations on the mutagenicity of pesticides in mammalian test systems

Comparative investigations on the mutagenicity of pesticides in mammalian test systems

Comparative investigations on the mutagenicity of pesticides in mammalian test systems

Comparative investigations on the mutagenicity of pesticides in mammalian test systems

The Mutagenicity of Pesticides, by S. S. Epstein and M. S. Legator [Review

The Mutagenicity of Pesticides, by S. S. Epstein and M. S. Legator [Review