The computational complexity of privacy information retrieval protocols is often linearly related to database size. When the database size is large, the efficiency of privacy information retrieval protocols is relatively low. This paper designs an effective privacy information retrieval model based on hybrid fully homomorphic encryption. The assignment method is cleverly used to replace a large number of homomorphic encryption operations. At the same time, the multiplicative homomorphic encryption scheme is first used to deal with the large-scale serialization in the search, and then the fully homomorphic encryption scheme is used to deal with the remaining simple operations. The depth of operations supported by the fully homomorphic scheme no longer depends on the size of the database, but only needs to support the single homomorphic encryption scheme to decrypt the circuit depth. Based on this hybrid homomorphic encryption retrieval model, the efficiency of homomorphic privacy information retrieval model can be greatly improved.