Multiple Viral Warts Research Articles

Clinical evidence of 595nm pulse dye laser treatment for viral warts on hands and feet.

Viral warts, induced by infection by different HPV genotypes, are highly frequent in the general population, particularly during infancy and among adolescents. The effectiveness of the 595nm Pulse dye-laser in treating viral warts on the hands and feet in both adults and children was investigated in this study. A selection of 203 patients with multiple viral warts was made. All patients underwent 4-5 treatment sessions with a 595nm pulse Dye Laser (PDL). Treatment outcome was assessed by a quartile scale: 1 indicates no or low results (0%-25% of the lesion area cleared), 2 indicates slight clearance (25%-50% of the lesion area cleared), 3 indicates moderate-good clearance (50%-75%), and 4 indicates excellent clearance (75%-100%). Patients were asked for a subjective evaluation of the perceived overall results by means of the following score: unsatisfied (1), not very satisfied (2), satisfied (3), and very satisfied (4). Possible side effects were monitored. Results obtained were judged with a photographic evaluation, immediately and at the control visit (6 months after the last laser session). All patients observed global improvements. Most of the lesions were completely removed after laser therapy. A total of 95% of patients achieved excellent clearance and they were very satisfied following the laser treatment. Relevant side effects were absent in all patients. PDL treatment with the study device using a wavelength of 595nm has proven to be a tolerable and safe therapy for viral warts management.

Efficacy of Autoinoculation in Treatment of Multiple Viral Warts - A Single Arm Study

To test the effectiveness of autoinoculation of a wart in patients with multiple viral warts. An experimental study. Department of Dermatology, Pak Emirates Military Hospital (PEMH), Rawalpindi, from February 2021 to February 2022. Patients above 12 years of age, having more than 5 warts were included. Those getting any other treatment for warts were excluded. The procedure was performed on a total of 70 patients with warts on 3 sites i.e. face/neck, palmoplantar and multiple sites. The outcome was categorised into cleared (no wart), partially cleared (reduced number of warts than baseline), and no response (same or increased number of warts than baseline). Out of 70 patients, 54 (77.1%) patients showed complete response, 6 (8.6%) showed partial response and 10 (14.3%) showed no response at all. Out of 54 patients who showed complete response, 36 (66.6%) were cleared after only one inoculation, fifteen (27.7%) were cleared after two inoculations, and 3 (5.5%) were cleared after three inoculations. The results were statistically significant with p-value <0.05. Autoinoculation is a simple and minimally invasive procedure which proved to be very effective against all types of warts, with very promising results against palmoplantar warts. Viral warts, Multiple viral warts, Autoinoculation, Delayed hypersensitivity, Human papilloma virus (HPV), Palmoplantar warts, Immunity.

Evaluation of the Efficacy of Acitretin in the Treatment of Multiple Viral Warts: A Pilot Study

Evaluation of the Efficacy of Acitretin in the Treatment of Multiple Viral Warts: A Pilot Study

Comparative Study of Efficacy of Intralesional Purified Protein Derivative (PPD) Versus Intralesional Measles, Mumps, and Rubella (MMR) Vaccine in Management of Multiple Viral Warts.

Background:Multiple viral warts represent a frustrating challenge for both patients and physicians. Management is difficult, primarily due to recalcitrance to standard therapy and high recurrence rates. Recently, intralesional antigen immunotherapy has shown promising efficacy in the treatment of warts.Objective:The aim of our study was to compare efficacy and safety of intralesional PPD versus measles, mumps, and rubella (MMR) vaccine in the management of multiple warts.Materials and Methods:One hundred and five patients having multiple warts were randomly divided into group A (PPD), group B (MMR) and group C (normal saline), with 35 patients in each group. In each group, the largest wart was injected intralesionally with 0.1 mL of vaccine at 2 weeks interval until complete clearance or for a maximum of 8 weeks.Results:Out of 105 patients enrolled in the study, 27, 25, and 21 patients completed the study in group A, group B, and group C, respectively. Rest were lost to follow up due to various reasons such as pain and long treatment duration. Complete clearance was seen in 14 patients (51.85%) in group A, 14 patients (56%) in group B, and 0 patients in group C. Partial clearance was seen in four patients (14.81%) in group A, four patients (16%) in group B, and three (14.28%) patients in group C. Nine patients (33.33%) in group A, seven patients (28%) in group B and 18 (85.71%) patients in group C did not respond to immunotherapy.Conclusions:Intralesional immunotherapy by both vaccines is a promising, effective, and safe treatment modality with MMR having slight edge.

Comparative Study between Oral Zinc Sulphate, Amino Acids Chelated Zinc and Placebo in Treatment of Viral Warts

Background: Warts are tumors or growths caused by infection with Human Papilloma virus (HPV). More than 100 HPV subtypes are known. They are a common presenting disease in children and adolescents which spread by direct contact or autoinoculation. The aim of the Work: The aim of this work was to assess and compare the efficacy and safety of oral zinc sulphate and amino acids chelated zinc in treatment of viral warts. Patients and Methods: This cross sectional case control study included 60 patients with multiple viral warts who were collected from the Dermatology, STDs and Andrology outpatient clinic of Fayoum university hospital during the period from November 2014 to November 2015. The patients were 29 males and 31 females with ages ranging from 15 to 60 years. Results: There was statistically significant difference in degree of response in zinc and control groups as no patient in control group showed any response while in both zinc groups 27.5% of patients showed variable degrees of response. Also, there was no statistically significant difference in degree of response in both zinc groups. Conclusion: oral zinc in its both forms used in our study is safe but needs time to act and the response is not high, so it is not fit to be used as a monotherapy, but rather to be combined with other wart treatment modalities. Recommendations: More studies are needed to assess the therapeutic effect of zinc and its efficacy in combinations in warts treatment with higher doses and longer duration of treatment.

New proposal for the treatment of viral warts with intralesional injection of 5-aminolevulinic acid photodynamic therapy

Background: Although photodynamic therapy (PDT) using intralesional injection (ILI) can theoretically enhance the efficacy of the PDT, the effect of ILI-PDT on warts has not been reported in the literature so far. Methods: Eight patients with multiple viral warts were enrolled in the study. PDT was performed after the incubation for 1 h, followed by the ILI of aminolevulinic acid (ALA) into the warts. The treatment was repeated at 2–3 week intervals. Results: Fifty percent of patients showed good to cure response. Complete remission was observed in two patients. There was no apparent correlation between the initial severity of warts and the likelihood of response. No one reported severe adverse reaction. Conclusions: The present study suggests that intralesional administration of ALA might be a safe and effective treatment option of thick treatment-resistant warts and can be performed with a shorter incubation period.

Development of Multiple Viral Warts in a Patient Receiving the TNF-α Inhibitor Etanercept

The development, recurrence or exacerbation of some cutaneous viral infections, such as molluscum contagiosum, plantar warts and genital condylomata, in patients receiving treatment with tumor necrosis factor-α (TNF-α) antagonists have been described in the literature. We report the development of multiple viral warts in a patient receiving the TNF-α inhibitor etanercept, and their resolution only after the discontinuation of the biologic therapy. TNF-α has an important role in the immune response to infection, including antiviral defense that is probably compromised by TNF-α inhibitors. Patients treated with TNF-α inhibitors may have a higher susceptibility to viral skin infections, and physicians should be aware of this potential complication.

Oral zinc sulphate in recalcitrant multiple viral warts: a pilot study

Journal of the European Academy of Dermatology and VenereologyVolume 23, Issue 6 p. 715-716 Oral zinc sulphate in recalcitrant multiple viral warts: a pilot study A Sadighha, Corresponding Author A Sadighha Correspondence: A Sadighha. E-mail: [email protected]Search for more papers by this author A Sadighha, Corresponding Author A Sadighha Correspondence: A Sadighha. E-mail: [email protected]Search for more papers by this author First published: 27 May 2009 https://doi.org/10.1111/j.1468-3083.2009.03169.xCitations: 8 DOI: 10.1111/j.1468-3083.2009.03169.x Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article.Citing Literature Volume23, Issue6June 2009Pages 715-716 RelatedInformation

Evaluation of oral zinc sulfate effect on recalcitrant multiple viral warts: A randomized placebo-controlled clinical trial

Evaluation of oral zinc sulfate effect on recalcitrant multiple viral warts: A randomized placebo-controlled clinical trial

CO2 Laser Treatment of Warts in Immunosuppressed Patients

Background: A large proportion of chronically immunosuppressed patients suffer from recalcitrant viral warts. Furthermore, the incidence of nonmelanoma skin cancer is clearly elevated in this patient group and human papillomavirus is most likely to play a causal role in these neoplasms. Objective: To analyze the effectiveness of treatment of viral warts with the CO₂ laser in immunosuppressed patients. Methods: Multiple viral warts of 13 patients with immunosuppression, a majority of them renal allograft recipients, were treated with CO₂ laser in local or regional anesthesia. In case of recurrences, the lesions were treated again after 3 months. Results: 12 of 13 patients experienced dramatic improvement after 1–3 treatment sessions, 6 of these patients showed full remission. Side effects such as postoperative pain or scarring were minimal. Conclusion: CO₂ laser treatment of recalcitrant warts in immunosuppressed patients shows promising results which are comparable to those in immunocompetent hosts. This offers a welcome enlargement of the array of therapies in this otherwise difficult-to-treat group of patients and may contribute to the reduction of risk factors for nonmelanoma skin cancer.

Cimetidine therapy for multiple viral warts in children

Cimetidine therapy for multiple viral warts in children

Treatment of resistant multiple viral warts with cimetidine: A controlled clinical trial

Treatment of resistant multiple viral warts with cimetidine: A controlled clinical trial

Cimetidine therapy for multiple viral warts in children

Cimetidine therapy for multiple viral warts in children