ABSTRACTIn order to prevent and detect a wide range of disorders, including those of the brain, thoracic, digestive, urogenital, and cardiovascular systems, ultrasound technology is essential for assessing physiological data and tissue morphology. Its capacity to deliver real‐time, high‐frequency scans makes it a handy and non‐invasive diagnostic tool. However, issues like patient movements and probe jitter from human error can provide a large amount of interference, resulting in inaccurate test findings. Techniques for image registration can assist in locating and eliminating unwanted interference while maintaining crucial data. Even though there has been research on improving these techniques in Matlab, there are no specialized systems for interference removal, and the procedure is still time‐consuming, particularly when working with huge quantities of ultrasound images. The phase correlation technique, which converts images into the frequency domain and makes noise suppression easier, is one of the most efficient algorithms now in use since it can tolerate noise with resilience. Nevertheless, little research has been done on using this technique to identify displacement in blood vessel wall ultrasound images. To address these gaps, this work presents an image registration system that uses the phase correlation algorithm. The system provides rotation, zoom registration, picture translation, and displacement detection of the vessel wall in addition to interference removal. Furthermore, batch processing is included to increase the effectiveness of registering multiple ultrasound pictures. Through efficient interference management and streamlined registration, this method offers a workable way to improve the precision and efficacy of ultrasonic diagnostics.