Multiple Kernel Learning Framework Research Articles

Fisher discrimination multiple kernel dictionary learning for robust identification of nonlinear features in machinery health monitoring

In sparse representation-based classification, Fisher discrimination dictionary learning (FDDL) has attracted widespread attention due to its advantages such as fewer parameters and good dictionary discriminability. However, due to its linear nature, it is difficult to handle nonlinear features. Kernel-based nonlinear transformation enables dictionary learning to capture nonlinear features embedded in samples, but traditional single-kernel methods have limited performance. In this paper, a Fisher discrimination multiple kernel dictionary learning (FDMKDL) method is proposed, in which Fisher discriminative criterion is imposed on both high-dimensional samples and coding coefficients. Specifically, we derive the kernel version of FDDL, i.e., Fisher discrimination kernel dictionary learning (FDKDL) to learn nonlinear features and promote dictionary discriminability. Meanwhile, to avoid the problem of poor adaptability and possible manual selection caused by single-kernel methods, we further derive a flexible multiple kernel learning (MKL) framework, which utilizes the complementary information of multiple kernel functions to adaptively obtain the optimal weights and synthesize a discriminative kernel space. Finally, FDMKDL combines FDKDL with this MKL framework to obtain a more discriminative dictionary. Experimental evaluations conducted on two datasets demonstrate the effectiveness and robustness of the proposed FDMKDL method in learning nonlinear features for machinery health monitoring when compared to several state-of-the-art methods.

A novel graph-based multiple kernel learning framework for hyperspectral image classification

ABSTRACT Multiple kernel learning (MKL) is an efficient way to improve hyperspectral image classification with few training samples by integrating spectral and spatial features. Nonetheless, presenting a MKL algorithm to capture significant information and eliminate redundancy is indispensable. In this paper, a novel graph-based MKL method (GMKL) is introduced to enhance the performance of the MKL algorithm and achieve high discriminative features, resulting in maximum separability. To do so, an informative low-rank graph is determined via a new algorithm called block diagonal representation that takes into account both local and global data structures. Then, in lieu of a time-consuming search for finding the optimal combination of the basic kernels, unlike the prior works, an optimal projective direction is acquired using graph theory. Various basic kernels generated from superpixels and attribute profiles are projected to produce a discriminative combination of kernels. Eventually, the optimum kernel is given to the support vector machine classifier. Experiments have been conducted on two popular hyperspectral datasets (Indian Pines and Pavia University). For the datasets, the proposed algorithm gained 90.43% and 99.28% overall accuracy, respectively, using only 1% training samples, which is much better than the state-of-the-art MKL algorithm and deep learning-based approaches with lower computational time.

Multiclassification of Hepatic Cystic Echinococcosis by Using Multiple Kernel Learning Framework and Ultrasound Images

To properly treat and care for hepatic cystic echinococcosis (HCE), it is essential to make an accurate diagnosis before treatment. ObjectiveThe objective of this study was to assess the diagnostic accuracy of computer-aided diagnosis techniques in classifying HCE ultrasound images into five subtypes. MethodsA total of 1820 HCE ultrasound images collected from 967 patients were included in the study. A multi-kernel learning method was developed to learn the texture and depth features of the ultrasound images. Combined kernel functions were built-in Support Vector Machine (MK-SVM) for the classification work. The experimental results were evaluated using five-fold cross-validation. Finally, our approach was compared with three other machine learning algorithms: the decision tree classifier, random forest, and gradient boosting decision tree. ResultsAmong all the methods used in the study, the MK-SVM achieved the highest accuracy of 96.6% on the fused feature set. ConclusionThe multi-kernel learning method effectively learns different image features from ultrasound images by utilizing various kernels. The MK-SVM method, which combines the learning of texture features and depth features separately, has significant application value in HCE classification tasks.

Neural Generalization of Multiple Kernel Learning

Multiple Kernel Learning (MKL) is a conventional way to learn the kernel function in kernel-based methods. MKL algorithms enhance the performance of kernel methods. However, these methods have a lower complexity compared to deep models and are inferior to them regarding recognition accuracy. Deep learning models can learn complex functions by applying nonlinear transformations to data through several layers. In this paper, we show that a typical MKL algorithm can be interpreted as a one-layer neural network with linear activation functions. By this interpretation, we propose a Neural Generalization of Multiple Kernel Learning (NGMKL), which extends the conventional MKL framework to a multi-layer neural network with nonlinear activation functions. Our experiments show that the proposed method, which has a higher complexity than traditional MKL methods, leads to higher recognition accuracy on several benchmarks.

Lq-norm multiple kernel fusion regression for self-cleansing sediment transport

Experimental and modeling studies have been conducted to develop an approach for self-cleansing rigid boundary open channel design such as drainage and sewer systems. Self-cleansing experiments in the literature are mostly performed on circular channel cross-section, while a few studies considered self-cleansing sediment transport in small rectangular channels. Experiments in this study were carried out in a rectangular channel with a length of 12.5 m, a width of 0.6 m, a depth of 0.7 m and having an automatic control system for regulating channel slope, discharge and sediment rate. Behind utilizing collected experimental data in this study, existing data in the literature for rectangular channels are used to develop self-cleansing models applicable for channel design. Through the modeling procedure, this study recommends Lq-norm multiple kernel fusion regression (LMKFR) techniques for self-cleansing sediment transport. The LMKFR is a regression technique based on the regularized kernel regression method which benefits from the combination of multiple information sources to improve the performance using the Lq-norm multiple kernel learning framework. The results obtained by LMKFR are compared to support vector regression benchmark and existing conventional regression self-cleansing sediment transport models in the literature for rectangular channels. The superiority of LMKFR is illustrated in an accurate modeling as compared with its alternatives in terms of various statistical error measurement criteria. The encouraging results of LMKFR can be linked to utilization of several kernels which are fused effectively using an Lq-norm prior that captures the intrinsic sparsity of the problem at hand. Promising performance of LMKFR technique in this study suggests it as an effective technique to be examined in similar environmental, hydrological and hydraulic problems.

Multiple kernel learning for label relation and class imbalance in multi-label learning

There are two common challenges in multi-label learning (MLL), complex label relation and imbalanced class. Few studies have focused on addressing both problems at the same time. In this paper, we propose a multiple kernel learning (MKL) approach to tackle two challenges, named as Multi-Kernel Multi-Label (MKML) method. MKML contains three kernel modules. The first kernel module adopts the traditional kernel function which contains the global information, and the other two kernel modules are designed for the two problems respectively. The second kernel module learns the inter-label relation by adding supervised information. The third kernel module adjusts the imbalanced decision boundary through multi-layer fusion strategy, which is proved to improve the representation ability of kernels in this paper. Finally, the proposed joint optimization method in this MKL framework achieves good generalization ability. We conduct several related experiments using real-world datasets to evaluate the effectiveness of our method. The results demonstrate that MKML outperforms other state-of-the art methods in MLL task.

A high-order norm-product regularized multiple kernel learning framework for kernel optimization

Kernels offer an effective alternative to implicitly embed the original data into a higher or infinite-dimensional space in support vector machines. Kernel learning, which attempts to determine optimal kernel functions to evaluate relationships between data, has garnered increasing interest. Employing multiple kernels to enhance optimality and generalization is a promising direction. In this study, we focused on the parameter optimization problem of Hadamard kernel functions, which is a newly proposed kernel in machine learning. Motivated by the multiple kernel learning framework in optimizing kernel combinations and the intriguing properties that L4-norm possess, we proposed a high-order L4Lp(p⩾3) norm-product regularized multiple kernel learning framework to optimize the discrimination performance, where hinge, log, and square loss functions are detailed. We demonstrated that the Hadamard multiple kernel learning can effectively obtain the optimal performance while implicitly avoiding the parameter specification difficulty by optimizing the linear combination of Hadamard kernel functions over different kernel parameters. The effectiveness of the proposed approach was verified through experiments on several benchmark datasets. In addition, the high-order L4Lp(p⩾3) norm-product regularized multiple kernel learning framework can be used to optimize radial basis function kernels under different kernel parameters.

Accurate cancer phenotype prediction with AKLIMATE, a stacked kernel learner integrating multimodal genomic data and pathway knowledge.

Advancements in sequencing have led to the proliferation of multi-omic profiles of human cells under different conditions and perturbations. In addition, many databases have amassed information about pathways and gene “signatures”—patterns of gene expression associated with specific cellular and phenotypic contexts. An important current challenge in systems biology is to leverage such knowledge about gene coordination to maximize the predictive power and generalization of models applied to high-throughput datasets. However, few such integrative approaches exist that also provide interpretable results quantifying the importance of individual genes and pathways to model accuracy. We introduce AKLIMATE, a first kernel-based stacked learner that seamlessly incorporates multi-omics feature data with prior information in the form of pathways for either regression or classification tasks. AKLIMATE uses a novel multiple-kernel learning framework where individual kernels capture the prediction propensities recorded in random forests, each built from a specific pathway gene set that integrates all omics data for its member genes. AKLIMATE has comparable or improved performance relative to state-of-the-art methods on diverse phenotype learning tasks, including predicting microsatellite instability in endometrial and colorectal cancer, survival in breast cancer, and cell line response to gene knockdowns. We show how AKLIMATE is able to connect feature data across data platforms through their common pathways to identify examples of several known and novel contributors of cancer and synthetic lethality.

Multiscale Adjacent Superpixel-Based Extended Multi-Attribute Profiles Embedded Multiple Kernel Learning Method for Hyperspectral Classification

In this paper, superpixel features and extended multi-attribute profiles (EMAPs) are embedded in a multiple kernel learning framework to simultaneously exploit the local and multiscale information in both spatial and spectral dimensions for hyperspectral image (HSI) classification. First, the original HSI is reduced to three principal components in the spectral domain using principal component analysis (PCA). Then, a fast and efficient segmentation algorithm named simple linear iterative clustering is utilized to segment the principal components into a certain number of superpixels. By setting different numbers of superpixels, a set of multiscale homogenous regional features is extracted. Based on those extracted superpixels and their first-order adjacent superpixels, EMAPs with multimodal features are extracted and embedded into the multiple kernel framework to generate different spatial and spectral kernels. Finally, a PCA-based kernel learning algorithm is used to learn an optimal kernel that contains multiscale and multimodal information. The experimental results on two well-known datasets validate the effectiveness and efficiency of the proposed method compared with several state-of-the-art HSI classifiers.

Robust kernelized graph-based learning

The studies of hidden complex structures in data have popularized the use of graph-based learning methods in semi-supervised and unsupervised learning tasks. Kernelized graph-based methods are proven to perform better, but these methods suffer from the issue of appropriate kernel selection. Instead of using multiple views, these methods generally use a single view. But multi-view methods need a proper weight assignment technique to each view in proportion to their contribution to the learning task. To solve this, a novel Self-weighted Multi-view Multiple Kernel Learning (SMVMKL) framework is proposed using multiple kernels on multiple views that automatically assigns appropriate weight to each kernel of each view without introducing an additional parameter. But the real-world data that is either noisy or corrupt with outliers which may effect the performance of the proposed SMVMKL method. To deal with this, a Robust Self-weighted Multi-view Multiple Kernel Learning (RSMVMKL) framework using the l2,1-norm has also been proposed that reduces the effect of outliers present in the data set. Both the proposed methods have been evaluated on multiple benchmark data sets and result in a performance comparable with the other state-of-the-art multi-view methods considered in this paper.

Classification and Graphical Analysis of Alzheimer's Disease and Its Prodromal Stage Using Multimodal Features From Structural, Diffusion, and Functional Neuroimaging Data and the APOE Genotype.

Graphical, voxel, and region-based analysis has become a popular approach to studying neurodegenerative disorders such as Alzheimer’s disease (AD) and its prodromal stage [mild cognitive impairment (MCI)]. These methods have been used previously for classification or discrimination of AD in subjects in a prodromal stage called stable MCI (MCIs), which does not convert to AD but remains stable over a period of time, and converting MCI (MCIc), which converts to AD, but the results reported across similar studies are often inconsistent. Furthermore, the classification accuracy for MCIs vs. MCIc is limited. In this study, we propose combining different neuroimaging modalities (sMRI, FDG-PET, AV45-PET, DTI, and rs-fMRI) with the apolipoprotein-E genotype to form a multimodal system for the discrimination of AD, and to increase the classification accuracy. Initially, we used two well-known analyses to extract features from each neuroimage for the discrimination of AD: whole-brain parcelation analysis (or region-based analysis), and voxel-wise analysis (or voxel-based morphometry). We also investigated graphical analysis (nodal and group) for all six binary classification groups (AD vs. HC, MCIs vs. MCIc, AD vs. MCIc, AD vs. MCIs, HC vs. MCIc, and HC vs. MCIs). Data for a total of 129 subjects (33 AD, 30 MCIs, 31 MCIc, and 35 HCs) for each imaging modality were obtained from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) homepage. These data also include two APOE genotype data points for the subjects. Moreover, we used the 2-mm AICHA atlas with the NiftyReg registration toolbox to extract 384 brain regions from each PET (FDG and AV45) and sMRI image. For the rs-fMRI images, we used the DPARSF toolbox in MATLAB for the automatic extraction of data and the results for REHO, ALFF, and fALFF. We also used the pyClusterROI script for the automatic parcelation of each rs-fMRI image into 200 brain regions. For the DTI images, we used the FSL (Version 6.0) toolbox for the extraction of fractional anisotropy (FA) images to calculate a tract-based spatial statistic. Moreover, we used the PANDA toolbox to obtain 50 white-matter-region-parcellated FA images on the basis of the 2-mm JHU-ICBM-labeled template atlas. To integrate the different modalities and different complementary information into one form, and to optimize the classifier, we used the multiple kernel learning (MKL) framework. The obtained results indicated that our multimodal approach yields a significant improvement in accuracy over any single modality alone. The areas under the curve obtained by the proposed method were 97.78, 96.94, 95.56, 96.25, 96.67, and 96.59% for AD vs. HC, MCIs vs. MCIc, AD vs. MCIc, AD vs. MCIs, HC vs. MCIc, and HC vs. MCIs binary classification, respectively. Our proposed multimodal method improved the classification result for MCIs vs. MCIc groups compared with the unimodal classification results. Our study found that the (left/right) precentral region was present in all six binary classification groups (this region can be considered the most significant region). Furthermore, using nodal network topology, we found that FDG, AV45-PET, and rs-fMRI were the most important neuroimages, and showed many affected regions relative to other modalities. We also compared our results with recently published results.

Stratifying patients using fast multiple kernel learning framework: case studies of Alzheimer\u2019s disease and cancers

BackgroundPredictive patient stratification is greatly emerging, because it allows us to prospectively identify which patients will benefit from what interventions before their condition worsens. In the biomedical research, a number of stratification methods have been successfully applied and have assisted treatment process. Because of heterogeneity and complexity of medical data, it is very challenging to integrate them and make use of them in practical clinic. There are two major challenges of data integration. Firstly, since the biomedical data has a high number of dimensions, combining multiple data leads to the hard problem of vast dimensional space handling. The computation is enormously complex and time-consuming. Secondly, the disparity of different data types causes another critical problem in machine learning for biomedical data. It has a great need to develop an efficient machine learning framework to handle the challenges.MethodsIn this paper, we propose a fast-multiple kernel learning framework, referred to as fMKL-DR, that optimise equations to calculate matrix chain multiplication and reduce dimensions in data space. We applied our framework to two case studies, Alzheimer’s disease (AD) patient stratification and cancer patient stratification. We performed several comparative evaluations on various biomedical datasets.ResultsIn the case study of AD patients, we enhanced significantly the multiple-ROIs approach based on MRI image data. The method could successfully classify not only AD patients and non-AD patients but also different phases of AD patients with AUC close to 1. In the case study of cancer patients, the framework was applied to six types of cancers, i.e., glioblastoma multiforme cancer, ovarian cancer, lung cancer, breast cancer, kidney cancer, and liver cancer. We efficiently integrated gene expression, miRNA expression, and DNA methylation. The results showed that the classification model basing on integrated datasets was much more accurate than classification model basing on the single data type.ConclusionsThe results demonstrated that the fMKL-DR remarkably improves computational cost and accuracy for both AD patient and cancer patient stratification. We optimised the data integration, dimension reduction, and kernel fusion. Our framework has great potential for mining large-scale cohort data and aiding personalised prevention.

Multilayer deep features with multiple kernel learning for action recognition

In accurate action recognition, discriminative human-region representation as auxiliary information is critical for fusing multiple visual clues in a video and further improving the recognition performance. To this end, in this paper we propose integrating a novel representation named multilayer deep features (MDF) of both the human region and whole image area into an extended region-aware multiple kernel learning (ER-MKL) framework. To be specific, we first exploit the human cues with the help of the off-the-shelf semantic segmentation models. Then more powerful representations MDF are constructed by concatenating activations at the last convolutional layer and fully connected layer. Finally, the proposed framework termed ER-MKL is presented to learn a robust classifier for fusing human-region MDF and whole-region MDF. In addition to combining multiple kernels derived from features of heterogeneous image regions, ER-MKL also considers the sets of pre-learned classifiers and incorporates prior knowledge of different regions. Extensive evaluations on the JHMDB and UCF Sports datasets validate the effectiveness and the superiority of our proposed approach.

A three-level Multiple-Kernel Learning approach for soil spectral analysis

To ensure the sustainability of the soil ecosystem, which is the basis for food production, efficient large-scale baseline predictions and trend assessments of key soil properties are necessary. In that regard, visible, near-infrared, and shortwave infrared (VNIR–SWIR) spectroscopy can provide an alternative for the expensive wet chemistry. In this paper, we examined the application of the Multiple-Kernel Learning (MKL) approach to soil spectroscopy by integrating the information from heterogeneous features. In particular, the proposed three-level MKL framework acts in the following way: at the first level, it uses multiple kernels at each spectral feature (wavelength) to maximize the information of each band. At the second level, it performs implicit feature selection at the spectral source level, enabling it to provide interpretable results. Finally, at the third level of integration it combines the complementary information contained within a pool of spectral sources, each derived from its own set of pre-processing techniques. Additionally, at this stage, the proposed approach is also capable of fusing heterogeneous sources of information, such as auxiliary predictors, which can assist the spectral predictions. The experimental analysis was conducted using the pan-European LUCAS (Land Use/Cover Area frame statistical Survey) topsoil database, with a goal to predict from the VNIR–SWIR spectra the concentration of soil organic carbon (SOC), a key indicator for agricultural productivity and environmental resilience. The particle size distribution which describes the soil texture was selected as the set of auxiliary predictors. The proposed MKL framework was compared with other state-of-the-art approaches, and the results indicated that it attains the best performance in terms of accuracy, whilst at the same time producing interpretable results.

Multiple Universum Empirical Kernel Learning

This paper proposes a novel framework called Multiple Universum Empirical Kernel Learning (MUEKL) that combines the Universum learning with Multiple Empirical Kernel Learning (MEKL) for the first time to inherit the advantages of both techniques. The proposed MUEKL not only obtained supplementary information of multiple feature spaces through MEKL, but also obtained priori information of samples by Universum learning. MUEKL incorporates a novel method, Imbalanced Modified Universum (IMU), to generate more efficient Universum samples by introducing the imbalanced ratio of data. MUEKL develops the basic multiple kernel learning framework by introducing a regularization of Universum data. The function of the introduced regularization is to adjust the classifier boundary closer to the Universum data to alleviate the influence of the imbalanced data. Moreover, MUEKL performs excellent generalization for both the imbalanced and balanced problems. Extensive experiments verify the effectiveness of the MUEKL and IMU.

Unsupervised Cross-Temporal Classification of Hyperspectral Images With Multiple Geodesic Flow Kernel Learning

With the increasing acquisition ability of hyperspectral remote sensing images, unsupervised cross-temporal classification (UCTC) of hyperspectral images (HSIs) has attracted more and more attention. In this paper, we focus on cross-temporal HSI classification, i.e., using one labeled HSI to classify the other unlabeled HSI. A multiple geodesic flow kernel learning (MGFKL) framework is proposed to exploit both spatial and spectral features for UCTC with bitemporal HSIs and called S2-MGFKL. The proposed S2-MGFKL method first extracts extended multi-attribute profiles (EMAPs) from the original bitemporal HSIs. The spatial features of the bitemporal HSIs obtained by the same attribute filter are paired up, so are the original spectral features. Second, each pair of features from both source and target domains are used to construct multiple geodesic flows. According to the original definition of GFK, we can obtain the construction of Gaussian base GFKs. The base kernels consist of two parts, the spectral part is obtained base on the same geodesic flow (which is constructed on the bitemporal spectral features) by tuning the kernel scale, while the spatial part is obtained under the same kernel scale but different geodesic flows constructed on different spatial feature pairs. After that, the mean rule is adopted to acquire the combined kernel, which is fed into the supervised vector machine (SVM) to implement the cross-temporal classification task. Experiments are conducted on two real HSI data sets, and the results compared with several well-known methods demonstrate the effectiveness of the proposed method.

Weight-based multiple empirical kernel learning with neighbor discriminant constraint for heart failure mortality prediction.

Heart Failure (HF) is one of the most common causes of hospitalization and is burdened by short-term (in-hospital) and long-term (6-12month) mortality. Accurate prediction of HF mortality plays a critical role in evaluating early treatment effects. However, due to the lack of a simple and effective prediction model, mortality prediction of HF is difficult, resulting in a low rate of control. To handle this issue, we propose a Weight-based Multiple Empirical Kernel Learning with Neighbor Discriminant Constraint (WMEKL-NDC) method for HF mortality prediction. In our method, feature selection by calculating the F-value of each feature is first performed to identify the crucial clinical features. Then, different weights are assigned to each empirical kernel space according to the centered kernel alignment criterion. To make use of the discriminant information of samples, neighbor discriminant constraint is finally integrated into multiple empirical kernel learning framework. Extensive experiments were performed on a real clinical dataset containing 10, 198 in-patients records collected from Shanghai Shuguang Hospital in March 2009 and April 2016. Experimental results demonstrate that our proposed WMEKL-NDC method achieves a highly competitive performance for HF mortality prediction of in-hospital, 30-day and 1-year. Compared with the state-of-the-art multiple kernel learning and baseline algorithms, our proposed WMEKL-NDC is more accurate on mortality prediction Moreover, top 10 crucial clinical features are identified together with their meanings, which are very useful to assist clinicians in the treatment of HF disease.

Randomized multi-scale kernels learning with sparsity constraint regularization for regression

This paper presents a simple multiple kernel learning framework for complicated data modeling, where randomized multi-scale Gaussian kernels are employed as base kernels and a [Formula: see text]-norm regularizer is integrated as a sparsity constraint for the solution. The randomly pre-chosen scales provide random basis functions with diversity approximation ability and lead to extremely low computational complexity in finding the optimal solution. The random parameter appearing in the probability distribution and the regularizing factor are decided by the training data with cross validation techniques and the combination weights are solved by a well-posed linear system. Comparison experiments on one function approximation and three real-world regression problems of six learning algorithms are carried out. The way that multi-scale kernels fit the objective function is illustrated, the sparsity and the system robustness analysis with respect to the regularizing factor are given.

Learning Distance Metric for Support Vector Machine: A Multiple Kernel Learning Approach

Recent work in distance metric learning has significantly improved the performance in k-nearest neighbor classification. However, the learned metric with these methods cannot adapt to the support vector machines (SVM), which are amongst the most popular classification algorithms using distance metrics to compare samples. In order to investigate the possibility to develop a novel model for joint learning distance metric and kernel classifier, in this paper, we provide a new parameterization scheme for incorporating the squared Mahalanobis distance into the Gaussian RBF kernel, and formulate kernel learning into a generalized multiple kernel learning framework, gearing towards SVM classification. We demonstrate the effectiveness of the proposed algorithm on the UCI machine learning datasets of varying sizes and difficulties and two real-world datasets. Experimental results show that the proposed model achieves competitive classification accuracies and comparable execution time by using spectral projected gradient descent optimizer compared with state-of-the-art methods.

Hyperspectral image classification based on multiple kernel mutual learning

Multiple kernel learning (MKL) is a popular and effective method for hyperspectral image classification. However, the communication and interaction among multiple basic kernels are insufficient among multiple basic kernels during the whole training process for traditional MKL methods. In this paper, a multiple kernel learning framework based on self-learning and mutual learning (MKML) is proposed. First, each basic kernel starts pretraining with its own training samples and then uses a trained model to make predictions. Second, the basic kernel selects some informative unlabeled samples with high entropy and queries other basic kernels for labeling. All basic kernels except the one that raised the problem negotiate together to determine the class label of the unlabeled samples. Third, the new pseudo-labeled samples are added to the initial training sample sets to train the model again. Finally, all basic kernels are combined to obtain excellent classification performance by the voting mechanism. The methodology is validated on three real hyperspectral images. The experimental results show that the proposed method exhibits better classification performance than well-known MKL methods.