AbstractTrajectory prediction is essential for intelligent autonomous systems like autonomous driving, behavior analysis, and service robotics. Deep learning has emerged as the predominant technique due to its superior modeling capability for trajectory data. However, deep learning‐based models face challenges in effectively utilizing scene information and accurately modeling agent interactions, largely due to the complexity and uncertainty of real‐world scenarios. To mitigate these challenges, this study presents a novel multiagent trajectory prediction model, termed the global‐local scene‐enhanced social interaction graph network (GLSESIGN), which incorporates two pivotal strategies: global‐local scene information utilization and a social adaptive attention graph network. The model hierarchically learns scene information relevant to multiple intelligent agents, thereby enhancing the understanding of complex scenes. Additionally, it adaptively captures social interactions, improving adaptability to diverse interaction patterns through sparse graph structures. This model not only improves the understanding of complex scenes but also accurately predicts future trajectories of multiple intelligent agents by flexibly modeling intricate interactions. Experimental validation on public datasets substantiates the efficacy of the proposed model. This research offers a novel model to address the complexity and uncertainty in multiagent trajectory prediction, providing more accurate predictive support in practical application scenarios.