The primary aspects of this research are to evaluate surface roughness, cutting force, and material removal rate and optimize it with dry milling process parameters for heat-treated and stir-cast AZ80 magnesium alloy. Multiple methodologies are utilized in the research, which includes the Integration of design of experiments-response surface methodology for experimental design with the technique for order of preference by similarity to ideal solution for multi-criteria optimization. In order to evaluate the effect of process parameters on the response, the experimental design manipulates the depth of cut, feed rate, and cutting speed in a systematic manner. An evaluation of the machined surface's quality is conducted via surface roughness measurements. Likewise, insights into the forces exerted during milling can be obtained through continuous monitoring of cutting forces. The calculation of material removal rate is predicated on weight reduction. The interaction between the depth of cut and feed rate has a significant impact on the critical-to-quality characteristics of the alloy, which has contribution percentage greater than 25%. This finding validates that despite the heat-treated alloy having a similar composition to the as-cast alloy (where the closeness coefficient is 0.9843), the optimal process parameters of the former are not applicable to the latter. Nevertheless, the technique used to prepare the specimen has no bearing on the material removal rate, which is a process parameter-specific effect.