Main restrictions in the realisation of multipass unstable resonators caused by intracavity losses and large-scale aberrations are considered. The influence of intracavity losses on the laser radiation power and divergence is analysed based on the numerical simulation of an unstable resonator. The efficiency criterion for the unstable multipass resonator is proposed, which is proportional to the radiation brightness and takes into account the influence of the misalignment, thermal deformation and the main parameters of the active medium and resonator on the parameters of laser radiation.