College student entrepreneurship teams can leverage the advantages of mobile internet resource integration and online collaborative production platforms to easily integrate various resources, thereby achieving rapid start-up and development of entrepreneurial projects. This also makes the threshold for college students to start businesses lower and easier to achieve. This article designs an interactive aesthetic education and entrepreneurship teaching system based on multimodal feature fusion and interactive systems. The core concept of the interactive aesthetic education and entrepreneurship teaching system is multimodal feature fusion and interactive system. Multimodal feature fusion can integrate different teaching resources, so that students can better understand the factors that need to be considered in the entrepreneurial process and practice. Interactive systems can enable closer interaction and communication between students and teachers, thereby better understanding and mastering entrepreneurial knowledge and skills. The design and implementation of a systematic system will help enhance the entrepreneurial ability and quality of college students, help them better understand the entrepreneurial process and factors that need to be considered in practice, and provide entrepreneurial practice reference for students in Chinese universities who have the intention of designing entrepreneurship.