This article delves into the evolution of international police cooperation, examining its origins, challenges, and significance in addressing transnational crime. The study highlights the influence of globalization, technological advancements, and increased international travel on criminal activities, which have necessitated more sophisticated and coordinated policing efforts across borders. The discussion traces the development of police cooperation from the 19th century, where crime was initially viewed through a moral lens, to the present day, where a more scientific and international approach to policing has emerged. The article underscores the complexities of multilateral and bilateral cooperation, each with its advantages and limitations. Multilateral efforts, exemplified by organizations like INTERPOL, promote accountability and transparency but are often hindered by bureaucratic challenges. Conversely, bilateral cooperation offers agility and direct engagement but faces issues of trust and accountability. The study concludes by advocating for the continuous refinement of international policing strategies, emphasizing the importance of tailored approaches to specific operational needs. Through effective collaboration, law enforcement agencies can better combat global crime networks and enhance international security in an increasingly interconnected world.