This paper investigates the predictive power of the macroscopic and microscopic models in alpha-decay of actinide nuclei. Macroscopic theoretical models such as Coulomb and Proximity potential model (CPPM), Modified generalized liquid drop model (MGLDM) and Effective liquid drop model (ELDM) are applied in predicting the alpha-decay half-lives of actinide nuclei. The half-lives produced by these macroscopic models are compared with that of microscopic models such as Cluster model with two-potential approach (CM), Microscopic cluster model (MCM), Multichannel cluster model (MCCM) and that of experiments. The deviation of these models with the experiments is quantified using statistical treatment such as root mean square deviation [Formula: see text] (RMSD), mean deviation ([Formula: see text]), index [Formula: see text] and root mean square error (RMSE). It is found that among the microscopic and macroscopic models, ELDM and MCCM are, respectively, found to be accurate than that of other models. The microscopic model MCCM produces alpha-decay half-lives close to the experiments in the actinide region. The appropriate mass excess values have been identified to predict the exact alpha-decay half-lives in the actinide region.
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