AbstractLeveraging the ultra‐wideband advantages of the terahertz band, Integrated sensing and communication (ISAC) facilitates high‐precision sensing demands in human smart home applications. ISAC channel characteristics are the basis for ISAC system design. Currently, the ISAC channel is divided into target and background channels. Existing researches primarily focus on the attributes of human target itself, e.g. radar cross‐section and micro‐Doppler effect. However, the impact of human target on neither the pathloss characteristic of background channel nor the multipath propagation characteristic of target channel is considered. To address the gap, we conduct indoor channel measurements at 105 GHz to investigate the ISAC channel characteristics with the impact of human target. Firstly, by analysing the power angular delay profiles with and without human target, the changes in quantity and power of multipath components (MPCs) are observed. Then, a parameter called power control factor is proposed to evaluate the human target impact on pathloss, thereby modifying the existing pathloss model of background channel. Eventually, the MPCs belonging to target channel are extracted within target‐oriented power delay profile to count the power proportion of each bounce MPCs of the target‐Rx link, which supports the necessity of multi‐bounce (indirect) paths modelling in target channel.