Smart Float is a new multi-modal underwater vehicle, a tool for ocean observation and detection, whose performance is limited by its underwater voyage distance and endurance like most underwater vehicles. The utilization of marine energy provides an ideal way to overcome these limitations. In this paper, an external ocean thermal energy power generation module is developed for Smart Float, which can be used for multiple times of energy storage and power generation and is expected to be further applied to small and medium-sized underwater vehicles. The integration of the proposed device will cause changes in the counterweight characteristic, hydrodynamic characteristic, and heat transfer characteristic of the vehicle, which are deeply analyzed in this study, and adaptive modification solutions are proposed according to the analysis results. Finally, a prototype of Smart Float integrating the proposed device was deployed in the South China Sea to perform a sea trial, to test its performance in thermal energy utilization. According to the results, the device generates 1.341 Wh in a profile diving to 700 m, with the maximum single-profile generation of 1.487 Wh, the average electrical energy of 1.368 Wh, and the hydraulic-to-electric efficiency of about 60% in the power generation stage, which verifies its excellent performance in thermal energy utilization. This study realizes the integration of thermal energy power generation modules into an underwater vehicle for the first time, exploring a new way to improve the endurance and self-sustainability of commercial underwater vehicles.