Research demonstrates that people draw on their religions in coping with difficult life circumstances, and that more religious people tend to cope better than less religious people. Lament is a religious prayer practice that constitutes a form of meaning-making coping. Here, we explicate this form of coping and, in a series of three studies with Christian participants, report on the development of a lament scale. In the first study, we develop items and test the items for clarity and for generalizability to diverse Christian groups using expert review and cognitive interviewing with participants representing five Christian groups. In the second study, we report results of exploratory factor analysis using data from primarily White and Protestant MTurk participants ( N = 303). In the third study, we report on factor stability and construct validity using data from largely White and African American Protestant and Catholic Prolific participants ( N = 346). The studies demonstrated generalizability to diverse Christian groups, a three-factor structure consistent with our theoretical formulation, good construct validity and relationships with well-being. Moderation analyses also indicated that when both Complaint and Praise are either high or low, the severity of the event is inversely related to flourishing. However, when either Complaint or Praise is high, the negative relationship between severity of the event and flourishing is ameliorated. The Lament Scale is a reliable and valid instrument for assessing lament in ways that are consistent with the conceptualization of lament as a meaning-making coping practice.