Summary The aim of this study is to determine the incidence of injuries in children aged from 1 to 16 years old who sustain a femoral fracture associated with a motor vehicle accident in the State of Qatar. It is a retrospective descriptive case series study conducted in the Accident Emergency Department at the Hamad General Hospital, State of Qatar, from January 1992 to December 2004. A total of 256 subjects aged 1–16 years with femoral fractures, secondary to a motor vehicle accidents were studied. All of them were seen at the Accident Emergency Department (AED), Critical Care, and Physiotherapy Departments of the Hospital. The socio-demographic information and the details of the injury of the studied subjects were collected. Of the 256 children, 82% of them were boys and 18% were girls with a male to female ratio of 4.6:1. Most femoral fractures were secondary to automobile-pedestrian accidents (43.4%), followed by motor vehicle crashes (30.1%). Of the 256 fractured femurs, 38 were open (15%) and 218 were closed (85%). Two hundred and ninety-eight associated injuries occurred in 240 patients (93.8%). Non-femoral fractures were common (46.6%), followed by soft-tissue injuries (21.5%) and head injuries (14.4%). The lower limbs were most commonly involved with associated fractures (38.1%), followed by upper limbs (27.4%) and soft-tissue injuries (21.4%). The incidence of intra-abdominal injury was 5.4%. Ninety children (35.2%) developed 1 or more complications. Furthermore, there was a statistically significant correlation between the duration of hospital stay and the fracture site ( r =0.820, p =0.01), and between age ( r =0.295, p =0.01) and type of injury ( r =0.241, p =0.01). The study revealed that the fracture of the femur secondary to motor vehicle accidents is a common injury among children in Qatar. There was an increased incidence of lower and upper limb injuries associated with femoral fracture in children involved in motor vehicle injuries. One third of the children developed one or more complications. Complications of injuries influenced the length of stay in hospital.