Considering the contradiction among the response speed, overshoot and stability of system when the motor load system adopts PID control, a control strategy combining RBF (Radial Basis Function) neural network supervisory control and expert PID control is designed to effectively improve this problem in this paper. First of all, the related algorithms of RBF neural network supervisory control composed of RBF neural network and PID control (RSC-PID) is introduced. This method can make the motor load system reach a steady state faster than simple PID control. But RSC-PID is also unsatisfactory in terms of overshoot. Based on the RSC-PID control method, a hybrid controller combining RBF neural network supervisory control and expert PID control (RSC-EPID) is proposed. This method combines RSC-PID control theory with expert PID control ideas, further improves the stability and rapidity of the system, reduces the overshoot. Moreover, when the input signal is a time-varying signal with interference, the motor load system shows better anti-interference performance after using RSC-EPID. The simulation results show that RSC-EPID control improves the tracking effect of the output signal of the motor load system, ensures the stability of the system, and improves the performance of the system.