Morphology Of SBA-15 Research Articles

Insights into H2S-absorption and oxidation-regeneration behavior of Ni-doped ZnO-based sorbents supported on SBA-15 for desulfurization of hot coal gas

Sulfur removal from hot coal gas is one of important technologies for highly efficient coal-based energy system. H2S-absorption and oxidation-regeneration behavior of Ni-doped ZnO-based sorbents supported on SBA-15 (ZnNi/SBA-15) was analyzed in this work. The results indicate that ZnNi/SBA-15 shows highest H2S-uptake capacity (16 g S/100 g sorbent) and lowest amount of produced COS (0.0004 g COS/100 g sorbent) when used for desulfurization at 500 °C. Removal of H2S at 700 °C leads to lowest breakthrough sulfur capacity of sorbents. It is ascribed to the destruction of typical microscopic morphology of SBA-15. Boltzmann function is suitable for modeling the H2S-absorption behavior of ZnNi/SBA-15. The evolution rate of H2S for sorbents varies from 0.096 to 0.228 min−1 at 400–700 °C. H2S-CO and H2S-CO2 reactions both contribute to the formation of COS at the stage of H2S-absorption saraturation. Increase of temperature from 550 to 600 °C results in the disappearance of ZnS in regenerated ZnNi/SBA-15. Moreover, most of plugged pore structure caused by sulfidation reaction could restore after regeneration at 600 °C. Further increase of regeneration temperature causes the decline of regeneration efficiency and less porous sorbent. Additionally, the sorbents have stable desulfurization ability and low COS emission during multiple sulfidation-regeneration cycles.

From the outside to the inside: Elucidation of the mechanism of pseudomorphic transformation of SBA-15 into MCM-41 by following its time-resolved conversion

Pseudomorphic transformation of silica materials is a versatile approach for the fabrication of porous phases in which the particle morphology and pore structure can be controlled independently from each other. It has been applied already for a wide variety of different parent silica materials, however, there is still a controversy about the details of the mechanism, about the manner of how the transformation proceeds through the body of the particles. The pure homogeneous distribution model on the one hand, and the core-shell model, on the other hand, are the so-to-speak extreme poles in this controversy, not excluding that a mixed-mode model can be valid for a particular parent silica phase. Herein, the detailed mechanism for the pseudomorphic transformation of ordered mesoporous SBA-15 into MCM-41 is elucidated by following the time-resolved conversion of the parent silica material. Upon pseudomorphic transformation, the characteristic morphology of the parent SBA-15 particles remains unchanged, whereas the original pore structure undergoes a successive restructuring in the presence of hexadecyl-trimethylammonium ions as a structure-directing agent. The inflow of the alkaline transformation solution within the pore system of SBA-15 initiates undirected dissolution and re-condensation processes of the pristine pore walls, resulting in an undulation, a slight shrinkage and a partial obstruction of the original mesopores. Simultaneously small domains of MCM-41 with various spatial orientations are formed on the external particle surface, restricting the access to the undulated mesopores within the particle core. The resulting core-shell structure of the partially transformed materials provides interesting gas physisorption hysteresis phenomena, caused by a cavitation mechanism during the evaporation of adsorbate from partially blocked SBA-15 pores. PXRD reflections that can be assigned to the characteristically large pore spacing of SBA-15 were found within patterns even for materials with a supposedly complete conversion. The occurrence of these reflections can be attributed to inaccessible pore domains of SBA-15. With proceeding transformation, a reduction of the amount of inaccessible SBA-15 pores was observed, finally leading to a material with typical MCM-41 characteristics but with a slightly less pore ordering due to the abrasively conditions during the long hydrothermal treatment. • Time-resolved pseudomorphic transformation of ordered mesoporous SBA-15 into MCM-41. • Original particle morphology of SBA-15 remained unchanged after transformation. • Bimodal mesoporous core-shell structures obtained by partial transformation. • Hysteresis phenomena in partially transformed samples caused by cavitation. • Inaccessibility of SBA-15 pore domains at partially transformed samples proven by nitrogen physisorption and PXRD.

Comparison of spherical and rod-like morphologies of SBA-15 for enzyme immobilization

Mesoporous silica, namely SBA-15, has been used for enzyme immobilization to help improve thermal stability of the enzymes and, in some cases, increase the enzymatic activity. It has been shown that morphology of SBA-15 is one of the factors influencing kinetics of enzyme adsorption. We reported, here, the adsorption kinetics and peroxidase activity of cytochrome c (cytc) in spherical SBA-15 in comparison of three different rod-like (fibrous, fiber, and rope) SBA-15 samples. The experimental adsorption profile fitted much better to the pseudo-second order than the pseudo-first order model. The maximum loading capacity of cytc was 466, 423, 390, and 352 mg/g for fibrous, rope, fiber, and spherical SBA-15, respectively. The rate constant for cytc adsorption for spherical SBA-15 was 3 times slower than rope and fiber SBA-15, and 15 times slower than fibrous SBA-15. The activity of cytc after immobilization in SBA-15 samples depended on the amount of cytc loading. The cytc loading in all SBA-15 at lower than 10 µmol/g showed higher activity than in free cytc in solution. The maximum activity of immobilized cytc was found in spherical SBA-15 at cytc loading of 1.00 µmol/g (~ 7 times higher than in free cytc). Finally, the Fe(III) at the heme group of cytc/SBA-15 samples with high activity was examined to contain high-spin state. The investigation in this work could suggest useful information for the preparation of SBA-15 for enzyme immobilization to appropriate applications, such as drug delivery.

Fabrication of AMP/SBA-15 with various morphologies for cesium removal from aqueous solution

In this work, mesoporous SBA-15 with different morphologies (platelets, rods, and fibers) were facilely fabricated and employed as a support for immobilization of Ammonium 12-Molybdophosphate (AMP, (NH4)3[P(Mo12O40)]). The obtained AMP/SBA-15 was then developed as a composite adsorbent to remove cesium (Cs) from an aqueous solution. The Cs+ adsorption onto the composite adsorbent was investigated as a function of AMP loading, contact time, pH, initial Cs+ concentration, and interfering cations. Our results show that the morphology of SBA-15 has a small effect on kinetic of the adsorption process and adsorption capacity through influence on the availability of active sites after AMP loading. The 50%AMP/P-SBA-15 with short pore showed the shortest equilibrium time and the highest adsorption capacity therefore delivering the best performance among the three morphologies. Selective adsorption results demonstrated that Na+, K+, Ca2+, and Mg2+ in solution do not interfere with Cs+ during the adsorption process on AMP/SBA-15 indicating high selectivity for Cs+. Hence, AMP/SBA-15 with platelet-shape morphology and short pore is an efficient adsorbent to remove Cs+ from an aqueous solution.

Lewis–Br⊘nsted induction acidity in SBA-15 modified with Zr and P

Abstract In this work, we present the synthesis of SBA-15 materials modified with 6 and 9 mol.% of Zr and P, respectively. Silanol SBA-15 groups were detected by Fourier transform infrared spectroscopy. X-ray diffractograms revealed that the typical hexagonal arrangement of SBA-15 was preserved after Zr and P introduction, and the structure was confirmed by transmission electron microscopy. After the Zr introduction, the morphology of SBA-15 changed from fibrous particles to a semi-spherical shape according to scanning electron microscopy, while nitrogen physisorption revealed the stability of the textural materials after the P introduction. The infrared spectra of pyridine adsorption indicated that the Zr and P incorporation into SBA-15 generated adequate Lewis and Br⊘nsted acidities to carry out methanol dehydration and direct the selectivity towards dimethyl ether, with medium-strong acid sites being responsible for obtaining up to 99% selectivity towards dimethyl ether.

Surface hydroxylation of SBA-15 via alkaline for efficient amidoxime-functionalization and enhanced uranium adsorption

A surface hydroxylation process with an alkali solution of low concentration was employed to recover surface silanol groups of SBA-15 prior to amidoxime (AO)-functionalization. The effect of concentration and temperature on surface hydroxylation were investigated, and the optimal conditions of 0.003 mol L−1 and 65 °C for the surface hydroxylation were determined. The silanol density was increased from 1.20 mmol g−1 of the untreated SBA-15 to 1.45 mmol g−1 of the hydroxylated SBA-15. Characterizations through scanning electron microscopy, transmission electron microscopy, X-ray diffraction, N2 adsorption-desorption proved that the hydroxylation process did not destroy mesopore structure and morphology of SBA-15. The hydroxylated SBA-15 could anchor more AO groups than the untreated SBA-15, resulting in higher U(VI) adsorption capacity (709 mg g−1) of the pristine AO-functionalized SBA-15 following hydroxylation than that of untreated sample (601 mg g−1). The adsorption capacity of the regenerated samples slightly decreased after three sorption-desorption cycles. Compared with other coexisting cations (Na+, K+, Mg2+, and Ca2+) in artificial seawater with rich uranium, the distribution coefficient (Kd) and concentration factor (CF) value of UO22+ were far larger, suggesting high selectivity of AO-H-SBA-15 for UO22+. These results indicate that the surface hydroxylation process can enhance U(VI) adsorption maintaining the high adsorption selectivity and long-term adsorption stability.

Sustained-release study on Exenatide loaded into mesoporous silica nanoparticles: in vitro characterization and in vivo evaluation

BackgroundExenatide (EXT), the first glucagon-like peptide-1 receptor agonist, has been approved as an adjunctive therapy for patients with type 2 diabetes. Due to EXT’s short half-life, EXT must be administrated by continuous subcutaneous (s.c.) injection twice daily. In previous studies, many studies on EXT loaded into polymer materials carriers for sustained release had been reported. However, these carriers have some defects, such as hydrophobicity, low surface energy, low mechanical strength, and poor chemical stability. Therefore, this study aims to develop a novel drug delivery system, which is EXT loaded into well-ordered hexagonal mesoporous silica structures (EXT-SBA-15), to control the sustainability of EXT.MethodsSBA-15 was prepared by hydrothermal method with uniform size. Morphology of SBA-15 was employed by transmission electron microscopy. The pore size of SBA-15 was characterized by N2 adsorption–desorption isotherms. The in vitro drug release behavior and pharmacokinetics of EXT-SBA-15 were investigated. Furthermore, the blood glucose levels of diabetic mice were monitored after subcutaneous injection of EXT-Sol and EXT-SBA-15 to evaluate further the stable hypoglycemic effect of EXT-SBA-15.ResultsEXT-SBA-15 showed a higher drug loading efficiency (15.2 ± 2.0%) and sustained-release features in vitro. In addition, pharmacokinetic studies revealed that the EXT-SBA-15 treatment group extended the half-life t1/2(β) to 14.53 ± 0.70 h compared with that of the EXT solution (EXT-Sol) treatment group (0.60 ± 0.08 h) in vivo. Results of the pharmacodynamics study show that the EXT-SBA-15 treatment group had inhibited blood glucose levels below 20 mmol/L for 25 days, and the lowest blood glucose level was 13 mmol/L on the 10th day.ConclusionsThis study demonstrates that the EXT-SBA-15 delivery system can control the sustainability of EXT and contribute to improve EXT clinical use.Graphical abstract

Preparation and Characterization of Magnetic Cobalt Ferrites/SBA-15 Nanocomposite Adsorbents and the Removal of Methylene Blue

In this paper, ordered mesoporous SBA-15 silica was synthesized by the hydrothermal method, and then a series of CoFe2O4/SBA-15 nanocomposites were synthesized by a facile impregnation method. X-ray diffraction and N2 adsorption–desorption isotherms were used to characterize the microstructure and morphology of SBA-15 and CoFe2O4/SBA-15 nanocomposites. CoFe2O4 nanoparticles presented spinel phase structure and existed in the mesopores of SBA-15. The magnetic response of CoFe2O4/SBA-15 nanocomposites was characterized with vibrating sample magnetometer (VSM). The adsorption efficiency of CoFe2O4/SBA-15 nanocomposites for methylene blue increased firstly with the increasing CoFe2O4 content, and then decreased. Sample-2 (SBA-15: CoFe2O[Formula: see text]: 0.1 in the precursor) not only presented the best adsorptive performance, but also could be separated and retrieved effectively by magnetic separation technique.

Evaluation and characterization of the encapsulation/entrapping process of octyl methoxycinnamate in ordered mesoporous silica type SBA-15

Encapsulating/entrapping UV filters into a SBA-15 matrix represents an interesting method to increase the photostability of filters. Octyl methoxycinnamate (OMC) is frequently used as an organic UVB filter in sun care products. However, this filter is unstable upon radiation and has the undesirable ability to permeate into the viable layers of the skin. Recognizing these issues, the aim of this research was to encapsulate/entrap OMC into SBA-15 and to characterize this material by physicochemical analytical techniques. Scanning electron microscopy proved to be an efficient tool to evaluate the structural morphology of SBA-15. The diffraction laser results showed that the particle size diameter of SBA-15 was 15.7 ± 0.46 µm. The decrease in the surface area and in mesoporous volume (V) observed in the nitrogen adsorption desorption isotherms of encapsulated/entrapped samples indicated that OMC was efficiently encapsulated/entrapped into SBA-15. Additionally, SAXS results showed that OMC did not affected the hexagonal structure of the mesoporous material and that OMC filled the SBA-15 pores. The FTIR spectrum of encapsulated/entrapped samples displayed characteristic absorption bands of free OMC, confirming the presence of this compound after loading. DTA curves of encapsulated/entrapped materials showed that the thermal stability of OMC was increased. On the other hand, DSC curves of encapsulated/entrapped materials demonstrated that thermal stability of OMC was not increased. Finally, thermogravimetric and elemental analysis were efficient tools to confirm the presence and the quantity of OMC into SBA-15.

Adsorption of uranium from aqueous solution by mesoporous SBA-15 with various morphologies

SBA-15 with various morphologies was prepared and employed to adsorb uranium from aqueous solution. The effect of morphology of SBA-15 on the adsorption performance of uranium was investigated. Furthermore, variables of the adsorption experiments (initial concentration, pH of initial solution and contact time) were investigated. The result of kinetic experiments showed that uranium adsorption followed pseudo-second-order kinetics model and the isothermal data agreed with the Langmuir model. It was found that the platelet-like morphology SBA-15 exhibits very rapid (<10 min to reach equilibrium) and high capacity (up to 401 mg g−1) adsorption of uranium.

Impact of support pore structure and morphology on catalyst performance of VOx/SBA-15 for selective methane oxidation

The impact of SBA-15 support properties on the catalytic performance of final VOx/SBA-15 catalysts for the selective oxidation of methane toward formaldehyde was studied. Three different SBA-15 support samples were prepared by varying the ageing temperature (50, 70, 90°C; 24h each). Afterwards, vanadium oxide species were deposited by a generally known impregnation procedure. Catalytic tests were carried out in a fixed bed tubular reactor at 540–650°C, a feed molar ratio of CH4: O2=9: 1 and at a gas-hourly space velocity of 360,000L/(kgcat∙h). Among the three catalysts, the highest formaldehyde selectivity was obtained with the sample aged at 70°C. Characterizations carried out by nitrogen physisorption, XRD, UV–vis spectroscopy and SEM revealed that the ageing temperature has a considerable influence on pore diameters, surface areas as well as the particle morphology of SBA-15. It is suggested that pore geometry as well as particle morphology have a considerable influence on the generation of various vanadia species and thus, on the catalytic performance of VOx/SBA-15 catalysts.

Effect of Mesoporous Silica Support on the Performance of Copper/Zinc Oxide Catalyst in Hydrogenation of CO&lt;sub&gt;2&lt;/sub&gt; to Methanol

Cupper/zinc oxide catalyst supported on mesoporous silica (SBA-15) prepared at different sol acidity have been synthesized. The influence of preparation conditions on the textural properties and morphology of the mesoporous silica were investgated. The morphology and textural properties of the SBA-15 synthesized through the acidic route was found to be strongly influence by the pH of the synthesis sol. The effects of supported Cu/ZnO catalyst in CO2 hydrogenation was investigated in a three-phase reactor system at 483K, 22.5bar, and H2/CO2 of 3. The catalytic preformance was found to be strongly affected by the morphology of SBA-15. The maximum in the methanol synthesis activity (57.8 %) and methanol selectivity (66.4) was attained for the catalyst supported by SBA-15 synthesized at lower acidity (pH of 2).

Photocatalysis by morphologically tailored mesoporous silica (SBA-15) embedded with SnO2 nanoparticles: Experiments and model

Commonly obtained SBA-15 particles (fiber-like morphology), if used as a catalyst-host, has limitations in diffusion of reactant molecules (e.g. of a dye) inside the pores of the SBA-15 particle. The systematic synthetic approach developed here provides an easy control of SBA-15 particle morphology over a wide range (fiber, rod, and sphere), by only varying the HCl concentration. To assess its effect on molecular diffusion and reaction inside pores, SnO2 nanoparticles of 3.5nm diameter were synthesized in situ, inside the 6.3nm diameter pores of SBA-15. These hybrids were tested for photocatalytic degradation of rhodamine B dye. Sphere-like morphology of SBA-15 with SnO2 nanoparticle loading of 17.7wt% showed the highest first-order degradation rate constant of 0.54h−1, compared to other morphologies (rod—0.51h−1, fiber—0.33h−1). On incorporating rates of diffusion, adsorption, and degradation-reaction of the dye in a single pore-level mathematical model of the SBA-15 particle, we have predicted the experimentally measured temporal variation of dye concentration for different SBA-15 morphologies and SnO2-catalyst loadings. Therefore, the present work identifies the best SBA-15 particle morphology (sphere-like) for such reactions and provides a validated model to optimize such coupled problems of chemical transport and reaction.

Mesoscopic simulation of surfactant/silicate self-assembly in the mesophase formation of SBA-15 under charge matching interactions

Ordered mesoporous silica SBA-15 with uniform hexagonal tunable mesopore channels attracts significant interest of the intensive studies and finds numerous applications in adsorption, catalysis, controlled release and drug delivery, etc. It is generally considered that such a unique hexagonal mesopore system of SBA-15 is formed via the cooperative self-assembly of partially protonated nonionic surfactants and positively charged silicate oligomers. However, the information about the assembly mechanism and the phase transformation at mesoscopic level is still insufficient due to the limitation of experimental technology. In this paper, Mesoscopic Dynamics (MesoDyn) simulation method is employed to investigate the phase transformation in the synthesis of SBA-15 with a simple Gaussian model, and a successive phase transition process composed of various mesophases of SBA-15 including spheroidal, columnar, and hexagonal phase are obtained. Moreover, the effects of charge matching interactions between surfactants and silicate species on the mesophase morphology of SBA-15 are further discussed. The obtained results are in good agreement with the ab initio calculations and the experimental results reported before, which indicates that the MesoDyn simulation method can be used to fundamentally validate and interpret the “surfactant/silicate species cooperative formation mechanism” of ordered mesoporous materials.

Investigation of chromium oxide clusters grafted on SBA-15 using Cr-polycation sol

A comparative study of chromium oxide clusters grafted on mesoporous silica SBA-15 was carried out using samples synthesized by one-pot, impregnation and Cr-polycation sol grafting methods. The nature of CrOx species incorporated into SBA-15 by direct hydrothermal one-pot method as well as impregnation of Cr(NO3)3·9H2O and Cr-polycation precursors was characterized by XRD, BET isotherms, UV–Vis DRS, FTIR, TGA, O1s XPS, 29Si-MAS NMR, H2-TPR, NH3-TPD, SEM and TEM. Powder XRD did not show the presence of Cr2O3 in the calcined samples obtained by one-pot method. It, however, shows the rhombohedral clusters of α-Cr2O3 dispersed over SBA-15 for CrOx/SBA-15 samples prepared by impregnation and polycation sol grafting methods. The absorption band at 296 nm, observed for Cr3+ in solution, is absent for the aqueous Cr-polycation sol. There is evidence that the presence of chromium precursor in the reaction medium can influence the morphology of SBA-15 as seen in the SEM micrographs. Charge transfer transitions demonstrate the insertion of CrOx species on SBA-15 matrix synthesized by one-pot method. Cr-polycation grafted SBA-15 sample shows unique vibrational features at 573 and 624 cm−1 attributed to extra-framework CrOx species. The ratio of Cr6+/Cr3+ species present in CrOx/SBA-15 samples depends on the Cr-precursor employed for grafting on SBA-15. One-pot synthesized samples predominantly contain coordinated water (δH–O–H at 1,635 cm−1) on SBA-15 while impregnated samples show water molecules associated with CrOx species (δH–O–H at 1,594 cm−1).

TiO 2 supported on rod-like mesoporous silica SBA-15: Preparation, characterization and photocatalytic behaviour

TiO 2 nanoparticles have been successfully incorporated in the pores of mesoporous silica SBA-15 with different morphologies by a wet impregnation method. The composites were characterized by powder X-ray diffraction (XRD), scanning electron microscopy (SEM), inductively coupled plasma (ICP) emission spectroscopy, transmission electron microscopy (TEM), N 2-sorption and UV–Vis diffuse reflectance spectroscopy. The photodegradation of methyl orange (MO) was used to study their photocatalytic property. It is indicated that the morphology of SBA-15 had a great influence on the photocatalytic activity of the composites. When TiO 2/SBA-15 composite was prepared by loading TiO 2 nanoparticles on uniform rod-like SBA-15 of 1 μm length, it showed higher photocatalytic degradation rate than that on less regular but much larger SBA-15 support. This difference was rationalized in terms of the homogeneously distributed and shorter channels of rod-like SBA-15, which favored mass transport and improved the efficient utilization of the pore surface.

A mechanistic study on the synthesis of MCM-22 from SBA-15 by dry gel conversion to form a micro- and mesoporous composite

A composite material with ordered pores in both the micro- and mesopore ranges was prepared by a dry gel conversion technique known as vapor-phase transport (VPT). Mesoporous silica SBA-15 was used as the SiO 2 source, and sodium aluminate was used as the Al 2O 3 source on the silica. VPT was then carried out under an atmosphere of hexamethyleneimine and water vapors. The unique microporous structure of MCM-22, a micropocket on the external surface of the zeolite, was generated at a late stage of crystallization. A zeolitic acid site, as strong as that of MCM-22 with mesopores originated from SBA-15, was achieved to create before the long-range ordering of the zeolite. A building unit of the zeolite was also formed at an early stage of crystallization. A drastic change in the morphology of SBA-15, promoted with the help of water vapor, took place during the course of crystallization. Slow crystallization and a structural support (e.g., carbon) inside the mesopores are necessary to prevent collapse of the mesostructure derived from the original SBA-15, and to obtain an ordered micro- and mesoporous composite material.

The effects on pore size and particle morphology of heptane additions to the synthesis of mesoporous silica SBA-15

The effect of heptane on the particle morphology and pore size in the synthesis of SBA-15 is presented. Heptane in the presence of NH 4F works as a pore swelling agent, resulting in 13–18 nm sized pores in 400 nm long and 200–1000 nm wide crystallites. The pores are hexagonally arranged and run through the crystallites. Increasing the heptane to P123 molar ratio changes the morphology of SBA-15 from fibers to sheets when the crystallites rearrange during the synthesis. The pore order in the sheets is controlled by changing the molar ratio of water to P123. The surface areas of these materials are 500–800 m 2/g with pore volumes of 1.2–1.7 cm 3/g. The sheets have accessible pores with a size of 18 nm running parallel to the sheet normal, which makes them suitable for membranes.

Preparation, characterization, and catalytic activity of chromia supported on SBA-15 for the oxidative dehydrogenation of isobutane

Abstract Mesoporous SBA-15 and 1–12 wt% CrO x /SBA-15 have been prepared by triblock copolymer P123-templated hydrothermal synthesis and incipient wetness impregnation method, respectively. The materials were characterized by means of a number of analytical techniques and their catalytic activities were evaluated for the oxidative dehydrogenation (ODH) of isobutane. It is found that with rise of chromia loading, the morphology of SBA-15 changed from long interconnected chains to short banana-like rods, and finally changed to spheres with wormholes. The results of Raman and X-ray photoelectron spectroscopic investigations reveal that the surface Cr species are mainly Cr 6+ in mono- and polychromate, with a minor amount of Cr 3+ due to α-Cr 2 O 3 formation. The H 2 temperature-programmed reduction study demonstrates that the catalysts at chromia loading of 6–10 wt% are more reducible. The 10 wt% CrO x /SBA-15 catalyst exhibits the best activity, showing 79% C 4 -olefin selectivity and 11% C 4 -olefin yield at 540 °C. One monolayer CrO x coverage on SBA-15 occurs at Cr surface density = 1.05–1.43 Cr-atom/nm 2 . We conclude that factors such as (i) presence of active Cr 6+ in mono- and polychromate, (ii) strong redox ability of Cr species, and (iii) good dispersion of CrO x on banana-like rods of well-ordered mesoporous SBA-15 are responsible for the good performance of the SBA-15-supported chromia in isobutane ODH.

Synthesis of carboxyl-modified rod-like SBA-15 by rapid co-condensation

Carboxyl-modified SBA-15 rod-like mesoporous materials have been synthesized by a facile rapid co-condensation of tetraethylorthosilicate (TEOS) and 2-cyanoethyltriethoxysilane (CTES), followed by hydrolysis of cyanide groups in sulfuric acid. The concentration of carboxylic groups was varied by changing the silica source ratio of CTES/TEOS from 0.05 to 0.3. X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM) showed that the uniform ordered mesoporous structure and rod-like morphology of SBA-15 have been preserved even at the high concentration of carboxylic groups employed. Characterization by Fourier transformed infrared spectroscopy (FTIR), solid-state NMR investigation indicated that carboxylic groups have been successfully grafted onto the surface of SBA-15 through siloxane bonds [(O 3)Si CH 2 CH 2 COOH. The negative charges of the modified SBA-15 materials were enhanced by the presence of the carboxylic groups on the surface. The capacity of lysozyme adsorption of the modified SBA-15 materials were found to be significantly improved as compared with pure silica SBA-15. The maximum amount of lysozyme adsorption on carboxyl-modified was increased with the pH of solution increased from 5.5 to 9.0.