Monometallic Copper Research Articles

Photoredox Oxidation of Alkanes by Monometallic Copper-Oxygen Complexes Using Visible Light Including One Sun Illumination.

Oxygenation of hydrocarbons offers versatile catalytic routes to more valuable compounds, such as alcohols, aldehydes, and ketones. Despite the importance of monometallic copper-oxygen species as hydroxylating agents in biology, few synthetic model compounds are known to react with hydrocarbons, owing to high C-H bond dissociation energies. To overcome this challenge, the photoredox chemistry of monometallic copper (pyrazolyl)borate complexes coordinated by chlorate has been explored in the presence of C1-C6 alkanes with BDEs ≥ 93 kcal/mol. Ethane is photooxidized at room temperature under N2 with yields of 15-30%, which increases to 77% for the most oxidizing tris(3,5-trifluoromethyl-pyrazolyl)borate complex (Cu-3). This complex also promotes the photooxidation of methane to methanol in significant yield (38%) when the photoredox reaction is run under aerobic conditions. Ligand modification alters the reaction selectivity by tuning the redox potential. The ability to activate 1° C-H bonds of C1-C6 alkanes using visible light is consistent with the photogeneration of a powerfully oxidizing copper-oxyl, which is supported by photocrystallographic studies of the tris(3,4,5-tribromopyrazolyl)borate chlorate complex. Mechanistic studies are consistent with the hydrogen atom abstraction of the C-H bond by the copper-oxyl intermediate. We demonstrate for Cu-3 with hexane as an exemplar, that the photoredox chemistry may be achieved under solar conditions of one-sun illumination.

A highly sensitive dual-mode detection platform based on the novel copper/molybdenum bimetallic nanoclusters and Co–Fe layered doubled hydroxide nanozyme for butyrylcholinesterase activity sensing

Herein, a novel copper/molybdenum bimetallic nanoclusters (Cu/Mo NCs) with intense blue emission were synthesized by using polyvinylpyrrolidone (PVP) as template and ascorbic acid as reducing agent. Owing to the synergistic effect between Cu and Mo, the fluorescence intensity of Cu/Mo NCs was significantly improved about 6-time than monometallic copper nanoclusters. A novel and sensitive ratiometric fluorescence and colorimetric dual-mode sensing platform for monitoring butyrylcholinesterase (BChE) was strategically constructed by the integration of Cu/Mo NCs with excellent optical properties and Co–Fe layered doubled hydroxide (CoFe-LDH) with superior peroxidase-like activity for the first time. In the presence of H2O2, nonfluorescent and colorless o-phenylenediamine (OPD) was oxidized to fluorescent and yellow 2,3-diaminophenazine (DAP) with maximum fluorescence emission peak at 564 nm and ultraviolet absorption peak at 418 nm by CoFe-LDH with peroxidase-like activity. Simultaneously, the generation of DAP could effectively quench Cu/Mo NCs fluorescence at 444 nm through the inner-filter effect (IFE). The hydrolysis of S-butyrylthiocholine iodide (BTCh) can be catalyzed by butyrylcholinesterase (BChE) to generate thiocholine (TCh) that could hinder the oxidation of OPD, leading to the fluorescence and ultraviolet absorption of DAP decreased, meanwhile, the fluorescence of Cu/Mo NCs recovered. The ratiometric fluorescence signal F564/F444 and colorimetric system both performed a satisfactory response to the concentration of BChE in the range 0.5 to 90 U L−1 and 1 to 100 U L−1 with the LOD of 0.18 U L−1 and 0.36 U L−1, respectively. The dual-mode sensing for BChE exhibited outstanding application potential in biosensing.

Electrocatalytic reduction of CO2 to C2H4 by monometallic Cu4 cluster supported on CeO2(110) surface

Cu-based catalysts have attracted much attention in the field of electrocatalytic CO2 reduction reactions (CRR). In our current work, the electrocatalytic reduction of CO2 by Cu cluster supported on CeO2 is calculated according to the density functional theory (DFT), and some interesting results are obtained. Monometallic copper cluster electrocatalysis of CO2 produce C2 products at lower potentials. The overpotential for the generation of ethylene is much lower than those of other products. The modulation of the substrate CeO2 changed the electronic structure of the Cu clusters and constructed Cu0 and Cu+1 active sites on the catalyst surface, and the coordinated action of Cu0 and Cu+1 made the C–C coupling more likely to take place and facilitated the generation of C2 products. The results of this study help to further understand the role of Cu-based catalysts in the electrocatalytic reduction of CO2 from theoretical point of view and provide guidance for future electrocatalytic experiments based on CRR.

Impact of substituents on luminescence and mechanochromism of two novel monometallic copper(I) complexes

Two new mononuclear Cu(I) complexes, [Cu(cbpy)(BINAP)]ClO4 (1) and [Cu(mcbpy)(BINAP)]ClO4 (2), have been synthesized and characterized (cbpy = 6-cyano-2,2ʹ-bipyridine, mcbpy = 4,4ʹ-dimethyl-6-cyano-2,2ʹ-bipyridine, BINAP = 2,2ʹ-bis(diphenylphosphino)-1,1ʹ-binaphthyl). Both Cu(I) complexes are photo-luminescent in the solid state at ambient temperature, with similar emission bands at 620 and 601 nm, respectively. Complex 2 exhibits the mechanochromic luminescence behavior with emission color changing from orange to orange-red, which is mainly due to the breakage of multiple CH⋯O hydrogen bonds between mcbpy-CH and counter-ion ClO4− under grinding. In contrast, the mechanochromic luminescence is not observed in 1 with much weaker cbpy-CH⋯O hydrogen bonds than those of 2. These clearly suggest that the methylation of 2,2ʹ-bipyridyl has an important effect on the mechanochromic luminescence properties of Cu(I) complexes. In addition, the potential applications of 2 have been investigated.

Biodiesel Production via Transesterification Reaction over Mono- and Bimetallic Copper-Noble Metal (Pt, Ru) Catalysts Supported on BEA Zeolite

This work focuses on the study of biodiesel production from commercial rapeseed oil and methanol via transesterification reactions on monometallic copper and bimetallic copper–noble metal (platinum, ruthenium) catalysts supported on BEA zeolite. The catalysts were prepared by wet impregnation method on the hydrogen form of BEA zeolite. As part of the study, the physicochemical and catalytic properties of the prepared catalytic materials were determined. The catalytic activity tests were carried out in the transesterification reaction over prepared catalysts at 220 °C for 2 h in an autoclave. The physicochemical properties of the obtained catalysts were investigated by X-ray diffraction (XRD), specific surface area and porosity (BET), a scanning electron microscope equipped with an energy dispersive spectrometer (SEM–EDS) and temperature-programmed desorption of ammonia (TPD-NH3) method. The results of the catalytic activity showed the promotional effect of the noble metal on the TG conversion and FAME efficiency of copper catalysts in the biodiesel production process. The most active catalyst turned out to be the calcined 5%Cu–1%Ru/BEA catalyst, which showed the highest TG conversion of 85.7% and the second highest FAME efficiency of 58.4%. The high activity of this system is explained by its surface acidity and large specific surface area.

Hydrogenolysis of glycerol over ZSM-5 supported ruthenium and copper catalysts: Structural study and effects in reaction

HZSM-5 supported bimetallic Ru-Cu catalysts were investigated with the objective of converting glycerol from biodiesel production into propanediols through the hydrogenolysis reaction. Two zeolites were used as supports, one with a SiO2/Al2O3 molar ratio of 80 and another with a ratio of 23. Physisorption analysis showed high specific area for the solids with values in the range of 400 m2 g−1, that enabled the metals to be incorporated as nanoparticles undetectable by XRD. Monometallic Ru catalysts displayed Ru0 species after reduction and RuO2 species duo to passivation, as evidenced by XPS analysis. Monometallic copper catalysts contained Cu0 and Cu+ species verified by XPS and DRIFTS after reduction and passivation, Cu2+ species were not found. As for the Ru-Cu bimetallic catalysts, Ru was added by impregnation of Cu/HZSM-5 and covered the copper nanoparticles as XPS analysis showed an increase in Ru/Cu molar ratio at the surface for both bimetallic catalysts. The XPS analysis showed increased Ru/Cu ratio at the surface for both bimetallic catalysts (1.95 and 2.94 for Ru-Cu/HZSM-5–80 and Ru-Cu/HZSM-5–23, respectively), furthermore no electronic effects between the two metals were observed indicating that the interaction between Ru and Cu consists in Ru diluting Cu. Chemisorption analysis show increase in CO adsorption for the bimetallic catalysts duo to the joint adsorptive capacity of Ru and Cu+, increasing from 141.4 µmol g−1 to 147.8 µmol g−1 for Ru-Cu/HZSM-5–80, and from 155.2 µmol g−1 to 198.5 µmol g−1 for Ru-Cu/HZSM-5–23, although the species adsorbed are thermally unstable compared to the monometallic adsorption, as shown by DRIFTS analysis. The activity of Ru catalysts was the highest (33 % and 32 % for catalysts supported on ZSM-5–80 and ZSM-5–23, respectively), but there was the formation of degradation products such as ethylene glycol. Copper catalysts showed moderate activity (11 % and 8 % for catalysts supported on ZSM-5–80 and ZSM-5–23, respectively) with good selectivity towards propanediols (22 % and 23 % for 1,2-PDO at isoconversion) duo to Cu0 and Cu+ interaction. Bimetallic catalysts Ru-Cu catalyst showed an improvement in selectivity to propanediols (36 % and 54 %) due to the interaction between Ru and Cu with low activity and reaction’s TOF (0.71 and 0.80 ×10−3 s−1).

NiOx-promoted Cu-based catalysts supported on AlSBA-15 for chemoselective hydrogenation of nitroarenes

Chemoselective hydrogenation of aromatic nitro compounds to the corresponding anilines is an environmentally benign technology for the production of key intermediates in manufacturing of pharmaceuticals, agrochemicals, dyes and fine chemicals. Non-noble metal Cu-based catalysts have been reported as a low-cost alternative but suffer from poor activity. Herein, by fabricating nickel oxide promoted Cu catalysts, a promoted activity was obtained in supported Cu-Ni bimetal catalyst system. Characterizations such as H2-TPR and XPS indicate a strong interaction between Cu and Ni, which contributes to its high activity and selectivity in hydrogenation of p-chloronitrobenzene (p-CNB) to p-chloroaniline (p-CAN). Control experiments suggest that either monometallic copper or pure nickel oxide is less active for the reaction but the interaction of NiOx with Cu generates much more active species, resulting in significantly improved catalytic reactivity and selectivity. The activity was found to be highly dependent on the contents of Cu0 & Cu+ in Cu-Ni bimetal catalyst, as the specific reaction rates for hydrogenation of p-CNB grew linearly with the increment of Cu0 & Cu+ loadings. Kinetic studies and in-situ DRIFTS of p-CNB imply the 10Cu-5Ni/AlSBA-R catalyst possesses good capacity for the activation of hydrogen and nitro group, leading to high p-CNB conversion and p-CAN production. The present work provides a good example for understanding the interaction between Cu and nickel oxides, and helps to develop highly efficient non-noble metal catalysts for selective hydrogenation of aromatic nitro compounds to corresponding anilines.

Catalytic Hydrogenation of Nitrocyclohexane with CuCo/SiO2 Catalysts in Gas and Liquid Flow Reactors

Catalytic hydrogenation of nitrocyclohexane proved to be an attractive alternative source of various chemical compounds: cyclohexanone oxime, cyclohexanone, cyclohexanol, cyclohexylamine and dicyclohexylamine. A growing interest in this reaction has been observed in the last few years. Herein, we present the catalytic performance of Cu/SiO2, Co/SiO2 and CuCo/SiO2 in gas and liquid flow nitrocyclohexane hydrogenation. The analysis of synthesized catalysts morphology (BET, TPR, XRD, TEM) in terms of their catalytic behavior allows us to draw general conclusions and determine the optimal conditions for the production of desired products. Application of the monometallic copper leads to the formation of cyclohexanone as the main product, but with low activity. On the other hand, Co/SiO2 shows high activity but gives cyclohexylamine. Bimetallic system CuCo(3:1)/SiO2 allows for the efficient production of 100% cyclohexanone at 5 bar and 75 °C.

Catalytic Performance of Bimetallic Systems (Cu-Fe, Cu-Mn, Fe-Mn) Based on Spherical MCM-41 Modified by Template Ion-Exchange in NH3-SCR Process

Mesoporous silica of MCM-41 type with spherical morphology was modified with copper, iron, or manganese as well as pairs of these metals by template ion-exchange (TIE) method. The obtained samples were characterized with respect to their structure (XRD), morphology (SEM-EDS), textural parameters (low-temperature N2 sorption), surface acidity (NH3-TPD), transition metal loadings (ICP-OES), their deposited forms (UV-vis DRS) and reducibility (H2-TPR). The catalytic performance of monometallic and bimetallic samples in the selective catalytic reduction of NO with ammonia (NH3-SCR) was tested. The best catalytic results presented a bimetallic copper-manganese sample, which was significantly more active than the mechanical mixture of monometallic copper and manganese catalysts. The synergistic cooperation of manganese and copper species is possibly related to charge relocation between them, resulting in activation of the catalyst in oxidation of NO to NO2, which is necessary for the fast NH3-SCR reaction.

FEATURES OF THE STUDY OF BIMETALLIC CONDUCTORS WITH SIGNS OF A SHORT CIRCUIT

In the process of investigating fires, the version of involvement in the occurrence of burning emergency modes in electrical equipment and electrical wiring often becomes one of the main ones. The consequence of the current overload of electrical conductors is the appearance of localized short circuit melting on them. In the indicated context, the most important stage of the study is the establishment of a direct or reverse causal relationship between a fire and a short circuit. The latter is possible due to the fact that the conductor metal is able to store situational trace information in the microstructure, which fixes the parameters of the state of the metal both during its solidification and after that, together with changes in the physicochemical (primarily temperature) environmental conditions. The main materials for the production of the most common cable products at the moment are copper and aluminium, which is the reason for the fullness of the existing methodological manuals with the development of instrumental methods for establishing the moment of occurrence of short circuits relative to fire exclusively for copper and aluminium conductors. Bimetallic conductors undeservedly remained outside the field of view of specialized methodological literature. The fact that this fact is an omission is evidenced by repeated cases of receipt of melted fragments of aluminium-copper wiring as objects of expert research in investigations into the causes of fires. The article pays special attention to the design of bimetallic conductors and the related features of the morphology of the melted areas to avoid erroneous interpretation of the melting of a short circuit of an aluminium-copper, as the deposition of foreign metal on a monometallic copper conductor. Also, the purpose of this work was to provide specialists who are to investigate short circuits on bimetallic aluminium-copper conductors, including with a metallographic analysis, information missing in the specialised methodological literature regarding the structural features and chemical composition of the short circuit melting metal on conductors of this type. An example from the expert practice of studying bimetallic (aluminium-copper) conductors with signs of a short circuit is given. The data presented in the article are based on studies using optical and scanning electron microscopy. Key words: metallographic analysis, short circuit, forensic fire expert, overcurrent, melting, bimetal, wiring.

Characterization and Optical Studies of Hydroxyethyl Cellulose-Copper Oxide Nanocomposites

In this study, monometallic copper oxide nanoparticles (CuONPs) were synthesized by chemical reduction of copper sulfate (CuSO4) salt through sugar glucose. X-ray diffraction profiles approved the formation of metallic oxide nanoparticles. TEM images showed spherical nanoparticles with an average particle size of 60 nm. The interaction of HEC and copper oxide nanoparticles was investigated by FTIR spectroscopy. The UV-visible absorption spectrum showed a surface plasmon resonance peak at 270 nm. The effect of doping of copper oxide nanoparticles (CuONPs) on the optical and thermal properties of HEC was studied. The results showed that the concentration of CuO nanoparticles has a prominent influence on the optical, structural, and thermal properties of hydroxyethyl cellulose.

Mononuclear copper(I) complexes bearing 1,3-bis(diphenylphosphino)propane and functional 6-Cyano-2,2′-bipyridine ligands

Two new monometallic copper(I) complexes bearing 1,3-bis(diphenylphosphino)propane (dppp) and functional 6-cyano-2,2′-bipyridine ligands, [Cu(dppp)(cbpy)](ClO4) (1) and [Cu(dppp)(mcbpy)](ClO4) (2) (cbpy = 6-cyano-2,2′-bipyridine; mcbpy = 4,4′-dimethyl-6-cyano-2,2′-bipyridine), have been synthesized and characterized. It is revealed that complexes 1 and 2 display a distorted N2P2 tetrahedral configuration formed by two N donors of the 2,2ʹ-bipyridyl ring and two P atoms of dppp. It is shown that the introduction of two electron-donating methyl groups at the 4- and 4′-positions of 6-cyano-2,2′-bipyridine is favorable for improving luminescence properties of Cu(I) complexes.

Electrochemical reduction of CO2 using oxide based Cu and Zn bimetallic catalyst

Electrochemical reduction of carbon dioxide (ERCO2) driven by non-conventional sources of energy is a favorable approach to generate closed loop CO2 cycle. It will reduce CO2 emissions by lowering CO2 levels in the atmosphere and converting it into high-energy-density carbon-based fuels like alcohols and hydrocarbons. Monometallic copper based catalysts are largely reported for ERCO2 to a variety of industrially important carbon products. But, challenges such as high over potential, uncontrollable product selectivity, and catalyst deactivation inhibit their progress. Oxide derived bimetallic CuZnx electrocatalysts have been suggested as alternatives for achieving high selectivity for different valuable products. In this study, the co-precipitation approach has been used to prepare CuO with various quantities of ZnO dopants. HRTEM, FESEM, XRD, and XPS were used to conduct detailed morphological and elemental studies on the electrode. The electrochemical performance was measured using H-type electrochemical cell in aqueous 0.1 M KHCO3 electrolyte. The evaluation of different CuO-ZnOx (where x=5, 10, 15 and 20 wt.%) catalysts for ethanol productivity and Faradaic efficiency are of particular importance. Amongst studied electrocatalysts, the highest Faradaic efficiency of 22.27 % was obtained for ethanol using CuO-ZnO10 at -0.80 V (vs RHE) with the production rate of about 121 µmol h−1 L−1. The optimized electrode (CuO-ZnO10) shows long term stability for at least 12 h. Post characterization of the catalyst was also conducted to obtain an insight into the active sites, which indicated that CO2 reduction took place on reduced oxide sites (i.e. metallic sites) rather than metal oxides.

Effect of Adding Transition Metals to Copper on the Dehydrogenation Reaction of Ethanol

The present work aims to investigate the effect adding Ag, Co, Ni, Cd and Pt to copper on ethanol dehydrogenation. The catalysts synthesized by deposition–precipitation method were characterized using various physicochemical methods such as N2 adsorption–desorption, TPR, SEM–EDX, XRD, XPS and TGA–DSC-MS. Catalytic evaluation results revealed that the predominant product of the reaction was acetaldehyde. Monometallic copper or mixed with Cd, Ag or Co show good catalytic performances. Adding nickel to copper improves the process conversion but reduces acetaldehyde selectivity, giving rise to methane in produced hydrogen. Pt-Cu/SiO2 catalyst guides the reaction towards diethyl ether. Time on stream tests performed during 12 h at 260 °C, showed that adding Cd to Cu enhances its stability by over 30% of conversion, this is explained by the reduction of copper crystallites sintering, which makes Cd-Cu/SiO2 a promising catalyst for the production of acetaldehyde by ethanol dehydrogenation.

Monometallic Copper Catalysts for the Hydrogenation of 5-Hydroxymethylfurfural

A catalytic system 3%Cu/CeO2–ZrO2 has been developed that allows the selective hydrogenation of 5-hydroxymethylfurfural to 2,5-bis(hydroxymethyl)furan with conversion of 70% and selectivity of 100% in 2 h at 170°C and hydrogen pressure of 10 atm. During the work, the effect of the amount of copper in the catalyst, its phase composition as well as the technique of copper deposition on the activity of the obtained samples was studied.

Investigation of effective factors on antibacterial activity of Pillared-Layered MOFs

Infectious diseases have become one of the main problems in the world, and many efforts are being made to deal with them. MOFs are new antibacterial agents that have received much attention due to their attractive properties. In this work, mono-metal [Cu2(bdc)2(dabco)] and mixed-metal [ZnCu(bdc)2(dabco)] pillared-layered MOFs, (H2bdc = terephthalic acid, dabco = 1,4-diazabicyclo[2.2.2]octane), were synthesized by solvothermal and sonochemical methods. Compounds were characterized by FT-IR, XRD, FE-SEM, ICP-OES and TGA techniques. The synthesis methods directly affected the stability of the MOFs, and the MOFs synthesized by the solvothermal method showed more thermal/chemical stability. The antibacterial activities of MOFs were investigated by agar well diffusion and broth dilution methods against Gram-positive and Gram-negative bacteria. Factors such as stability, metal type, and morphology were influential in antibacterial activity. Mono-metallic copper MOFs showed more antibacterial activity than the mixed-metal ones. Also, solvothermal samples were more effective than sonochemical samples. The effect of compounds against Staphylococcus aureus strain was more than Escherichia coli strain. According to results, Pillared-layered MOFs can be considered as affordable antibacterial agents with long-lasting activity.

Enhanced reduction reaction by Cu–Ag core-shell nanowire catalyst

The synthesis of well-defined copper core-silver shell nanowire by a modified hydrothermal method followed by immersion coating process is reported here. The HRTEM image of the individual Cu–Ag core-shell nanowire successfully demonstrates that the silver nanocrystals were effectively deposited over the surface of Cu nanowires, resulting in a core-shell structure by the immersion coating process. The catalytic performance of the prepared copper core-silver shell nanowires with different ratios have been investigated by taking the reduction of para nitrophenol to para aminophenol in presence of sodium borohydride as the model reaction. The Cu–Ag core-shell nanowires show remarkable catalytic activity toward the reduction of p-nitrophenol at room temperature with a maximum apparent rate constant value of 0.216 min−1. In comparison with the monometallic copper nanowires, the Cu–Ag core-shell nanowires exhibit 3.5 times enhancement in the catalytic performance and good recyclability for at least three cycles of the reduction reaction. Copper core-silver shell nanowire: a potential catalyst for the reduction of paranitrophenol was developed by a modified hydrothermal method followed by immersion coating process. Remarkable catalytic activity with a maximum apparent rate constant value of 0.216 min−1 was obtained. The use of eco-friendly reducing agent and the high purity synthetic approach makes this work significant.

Mechanistic Studies of Methanol Synthesis Reaction over Cu and Pd–Cu Catalysts

Monometallic copper and bimetallic palladium–copper catalysts supported on ZnO–Al2O3, CeO2–Al2O3 and ZrO2–Al2O3 were prepared by conventional impregnation method and tested in the methanol synthesis reaction in a gradient less reactor under elevated pressure (3.5 MPa) at 220°C. The physicochemical properties of prepared catalytic systems were studied using BET, TPR-H2, TPD-NH3, XRD, SEM-EDS and FT-IR techniques. The results of XRD and SEM-EDS measurements showed the formation of Pd–Cu alloy during the activation of bimetallic catalysts. It was found that the formed alloy was responsible for the improved activity and selectivity of catalysts in the studied reaction. Among investigated catalysts, the highest formation rate of methanol was observed with 2%Pd–20%Cu/ZnO–Al2O3 system. Based on the results of FT-IR measurements it can be concluded that hydrogen molecules adsorb dissociatively on the metallic copper surface to form hydrogen atoms, increasing the hydrogen spillover effect on the metal-support interface. In contrast, CO2 adsorb on the oxygen vacancies of the support to form carbonates, which can further undergo hydrogenation to methanol.

IR-spectrum of monometallic copper(II) halogenide complexes with 1-tert-butyl-1,2,4-tria zole: experimental and quantum chemical studies

The crystalline complexes CuL2X2 and CuL4X2 , where X = Cl or X = Br were synthesized by the interaction of copper(II) chloride or bromide with 1-tert-butyl-1,2,4-triazole (L) in water or organic solvents. The structure of metal complexes have been studied by elemental analysis, X-ray analysis and IR-spectroscopy in the medium (4000 –500 cm –1 ) and long-wavelength (400–50 cm –1 ) regions. Quantum chemical calculations of the vibrational spectra of the CuL2Cl2 and CuL4Cl2 complexes have been carried out to perform the assignment of the signals in the IR-spectra. It is shown that the polymer structure of CuL2X2 complexes is formed due to bridging of one of their halide ions. In the CuL4X2 complexes, the halide ions and 1-tert-butyl-1,2,4-triazole form an island type structure. In all metal complexes 1-tert-butyl-1,2,4-triazole is coordinated by N(4) atom of heterocycle.

Efficient oxidative degradation of fluconazole by a heterogeneous Fenton process with Cu-V bimetallic catalysts

In this study, a novel Cu-V bimetallic catalyst (CuVOx) with abundant surface defects was successfully synthesized by hydrothermal method. Degradation experiment of emerging pollutant fluconazole confirmed that CuVOx exhibited higher catalytic activity, wider pH applicability and more satisfactory reusability than monometallic copper compounds. Electron paramagnetic resonance and radical quenching tests indicated that surface hydroxyl groups play a crucial role in the degradation of contaminants. By the introduction of vanadium into copper-based materials, several surface properties that are closely related to the reactivity of the copper catalysts such as adsorption capacity, surface defects, and active sites concentration were improved. It was also found that the electron-rich center around Cu/V active sites and surface oxygen vacancies are responsible for the rapid dissociation of H2O2 and the efficient catalytic oxidation of fluconazole in CuVOx Fenton system. We also applied CuVOx Fenton to the degradation of various refractory organic pollutants, further confirming its excellent removal and detoxification efficiency for organic pollutants in the aquatic environment.