A wheat-bran soil inoculant containing 109/ml conidia of Monacrosporium eudermatum isolated from North Sumatera, Indonesia was used as inoculant. The potential of this fungi to control nematodes was compared with that achieved by using the chemical control agent carbofuran at 200μg/ml. A susceptible plant, ornamental Tobacco (Nicotiana sanderae) was inoculated with 1000 second juvenile of M. incognita per pot. Analysis of variance by Anova was used to find the significant differences between treatments. Based on mean value of plant height, stem fresh weight, stem dry weight, root depth and root fresh weight measurements, almost all treatments improved and enhanced the ornamental tobacco growth. Carbofuran and M. eudermatum was efficient in reducing the number of vermiform nematode and swollen roots after 7 days; mature, immature female and sausage shaped roots after 15 days; and immature and mature females, sausage shaped and galls after 30 days of infection by M. incognita. Treatment with M. eudermatum was seen to be comparable with carbofuran in reducing infection of M. incognita. Based on this study there was no evidence of resistance to Meloidogyne incognita in ornamental tobacco plants N. sanderae.