The response assessment of bridges crossing navigable waterways under vessel collisions is commonly conducted assuming intact bridge models. However, local scour may occur at bridge foundations, which has been identified as one of the major hydraulic causes of bridge failures. Therefore, it is imperative to consider local scour in the design and analysis of bridges against vessel collisions. Many previous studies have focused on the bridge response under vessel collisions assuming deterministic scour depths with incremental values, without integrating a scour prediction modeling in the analysis. This work investigates the barge-bridge collisions in the presence of scour at pile foundations, by using empirical scour prediction models. The accuracy of each prediction model is evaluated using relevant laboratory test and field measurement records. Finite element (FE) models of a four-span continuous reinforced concrete (RC) bridge and a jumbo hopper barge are developed in LS-DYNA. The current study identifies the correlation between the upstream flow depth and the barge collision location in the analyses. Numerical results illustrate that both scour depth and collision location influence the displacement, shear force, and bending moment response of bridge piles. The struck bridge pier accommodates a considerably increased displacement with an increased scour depth, while the shear force and bending moment are primarily influenced by the collision location. The influence of scour on the barge-pier collision force is marginal. The maximum axial force in soil springs increases considerably with scour depth. The choice of scour prediction model shows a significant impact on the displacement, shear force, bending moment of piles, the displacement of struck pier, and the axial force of soil springs.
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