Reversible luminescence modification has received considerable interest due to its potential applications in optical storage technology and high-sensitivity optical switches. However, there is no any report that multi-mode luminescence modification behavior can be achieved in one material so far. In this study, a novel multifunctional luminescence phosphor Sr2−xSnO4:xSm3+ has been developed. Photoluminescence, photoluminescence modulation associated with the photochromism reaction, photo-stimulated luminescence, thermoluminescence are realized in one single ceramic material Sr2−xSnO4:xSm3+. The optimized photoluminescence modulation ratio based on the photochromism reaction reaches 72.2%. Based on the photo-stimulated luminescence, the photoluminescence modulation ratio reaches an infinite value ∞, which provides a different approach for optical storage and can avoid the bit error in information storage. In addition, the mechanisms of photoluminescence modulation, photo-stimulated luminescence, thermoluminescence are analyzed. The diverse luminescence properties in Sr2−xSnO4:xSm3+ are tightly related to the formed defects induced by Sm3+ doping. The high integration level for fluorescence performances can widen the application of activator-doped oxides.