Modulation Of EEG Activity Research Articles

Changes in EEG Activity Following Live Z-Score Training Predict Changes in Persistent Post-concussive Symptoms: An Exploratory Analysis.

A specific variant of neurofeedback therapy (NFT), Live Z-Score Training (LZT), can be configured to not target specific EEG frequencies, networks, or regions of the brain, thereby permitting implicit and flexible modulation of EEG activity. In this exploratory analysis, the relationship between post-LZT changes in EEG activity and self-reported symptom reduction is evaluated in a sample of patients with persistent post-concussive symptoms (PPCS). Penalized regressions were used to identify EEG metrics associated with changes in physical, cognitive, and affective symptoms; the predictive capacity of EEG variables selected by the penalized regressions were subsequently validated using linear regression models. Post-treatment changes in theta/alpha ratio predicted reduction in pain intensity and cognitive symptoms and changes in beta-related power metrics predicted improvements in affective symptoms. No EEG changes were associated with changes in a majority of physical symptoms. These data highlight the potential for NFT to target specific EEG patterns to provide greater treatment precision for PPCS patients. This exploratory analysis is intended to promote the refinement of NFT treatment protocols to improve outcomes for patients with PPCS.

Noise power associated with decreased task-induced variability of brain electrical activity in schizophrenia.

In schizophrenia, both increased baseline metabolic and electroencephalographic (EEG) activities as well as decreased task-related modulation of neural dynamics have been reported. Noise power (NP) can measure the background EEG activity during task performance, and Shannon entropy (SE) is useful for quantifying the global modulation of EEG activity with a high temporal resolution. In this study, we have assessed the possible relationship between increased NP in theta and gamma bands and decreased SE modulation in 24 patients with schizophrenia and 26 controls over the parietal and central regions during a P300 task. SE modulation was calculated as the change from baseline to the active epoch (i.e., 150-550 ms following the target stimulus onset). Patients with schizophrenia displayed statistically significant higher NP values and lower SE modulation than healthy controls. We found a significant association between gamma NP and SE in all of the participants. Specifically, a NP increase in the gamma band was followed by a decrease in SE change. These results support the notion that an excess of gamma activity, unlocked to the task being performed, is accompanied by a decreased modulation of EEG activity in schizophrenia.

Modulation of cortical activity as a result of task-specific practice

This report aims to examine the role of task-specific practice in the modification of finger force enslaving and to provide empirical evidence for specific EEG frequency bands accompanying such practice may be an end-effectors dependent phenomenon. Nine handed naïve subjects without any training in music participated in a pre- and post-practice sessions separated by 12 practice sessions. Subjects performed a series of isometric force production tasks at 10% and 50% maximum voluntary contraction (MVC) with two rates of force development separately by index and ring fingers. Task-specific practice aimed at suppressing the contribution of neighboring fingers was achieved via visual feedback of force traces. Behavioral data (accuracy of force production and amount of force enslaving) and EEG data in frequency domain obtained via Morlet Wavelet transforms were analyzed. The major behavioral finding is that task-specific practice significantly enhanced the accuracy of force production and individuated control of the "most enslaved" ring finger (P<0.01), but not the index finger. The major novel EEG findings are: (a) modulation of EEG activity within alpha band (8-12 Hz) in the central area of the brain as a function of practice was similar for both fingers and (b) after practice, modulation of EEG activity within gamma (30-50 Hz) band was end-effectors specific. Both behavioral and EEG patterns suggest an effect of task-specific practice on the reduction of force enslaving and that modulation of practice-related plasticity in the human cortex is end-effectors dependent phenomena.