Modern Dressings Research Articles

Recent advances in the application of functional hydrogels in skin wound healing

AbstractThe effective treatment of skin wounds has long posed a significant challenge in the medical field, impacting patient comfort, quality of life, and the rate and outcome of wound healing. With continuous advancements in science and technology, novel materials have emerged, providing new possibilities for skin wound treatment. Among these, multifunctional hydrogels have shown considerable potential in promoting skin wound healing as a type of wound dressing material. This review systematically examines the progress in the application of multifunctional hydrogels in skin wound healing. Initially, the structure and composition of the skin are introduced. Subsequently, skin wounds are classified, and the wound‐healing process is discussed in detail. Traditional and modern dressings are then categorized, with a particular emphasis on the characteristics and applications of hydrogel dressings. The various functions of hydrogels in skin wound healing, including antibacterial, antioxidant, hemostatic, adhesive, stimulus‐responsive, and wound status monitoring, are reviewed. The paper concludes with a summary of the existing research gaps and provides insights into the future development directions of multifunctional hydrogels. This review aims to guide the preparation of hydrogel wound dressings and offer theoretical references for the exploration of next‐generation functional hydrogels.

Literature Review on the Effectiveness of Modern Dressing in the Wound Care Process on Diabetic Wound Healing

Background: Diabetes mellitus is a health problem due to insulin deficiency or insulin resistance that causes high blood glucose. A frequent complication is diabetic ulcer, which is a condition of partial or complete tissue deformity. If it does not get proper treatment, it is very risky to get an infection that leads to amputation.Diabetes Mellitus (DM) has become a prevalent disease, imposing a significant burden on public health due to its widespread occurrence and association with numerous disabilities and fatalities. Uncontrolled DM can lead to severe metabolic complications and long-term vascular issues, including microangiopathy and macroangiopathy. Additionally, individuals with DM are highly susceptible to foot infections, which can escalate into gangrene if not properly managed. Purpose: To determine the effectiveness of modern dressing in the wound care process on diabetic wound healing. Methods: Data collection used descriptive analysis and literature study. The databases used were PubMed, CINAHL, ProQuest and Web of Science. Journal inclusion criteria used PICO and article analysis was conducted by 6 authors. Findings: The evaluated article's findings elucidate the patient's degree of comfort and the more important healing process. It has been demonstrated that contemporary wound care applications make patients feel more at ease as their wounds heal, greatly aiding nurses in nursing care. Modern wound care is a practice that will evolve in response to advancements in nursing science; in this instance, it centers on how comfortable patients are while obtaining wound care-related medical treatments. Therefore, nurses must advance the knowledge behind the use of contemporary wound care to promote patient comfort and hasten the healing process. Conclusion: Modern wound care enhances patient comfort and accelerates healing, greatly supporting nursing practice. With evolving knowledge in nursing science, nurses need to master these methods to maximize patient comfort and recovery in wound care

Modern dressings with enzymes for comprehensive management of various etiology wounds

Modern dressings with enzymes for comprehensive management of various etiology wounds

Surgical treatment of a teenager with an extensive wound defect of soft tissues against the background of severe combined injury

Extensive posttraumatic wounds, affecting functionally active areas and complicated by a purulent–necrotic process, are a serious problem in the acute period of injury due to a critical condition and in reconstructive surgical treatment. This study presents the case of a 16-year-old victim of a transport accident on a ferry who underwent a surgical treatment. Due to a truck collision, the girl was crushed against the metal structure of the ship and received a severe combined injury: closed craniocerebral injury, moderate brain contusion, linear fracture of the occipital bone on the right, closed chest injury, fracture of 9–11 ribs on the right, closed abdominal injury, rupture of the right kidney, damage to the bladder, retroperitoneal hematoma on the right, closed spinal injury, fracture of the spinous processes of the L4–L5 vertebrae, open fractures of the pelvic bones, and extensive posttraumatic wounds of the right half of the pelvic girdle and hip joints. During the initial hospitalization, the following were performed within 2 days: laparotomy, nephrectomy of a crushed kidney on the right, suturing of the bladder, primary surgical treatment of the wound in the sacrogluteofemoral region on the right and the wound of the left thigh with their primary suturing, and external osteosynthesis of the pelvic bones with a rod-based external fixation device. The early postoperative period was complicated by necrosis of injured soft tissues and a new surgical infection (polyantibiotic-resistant strains of microorganisms), which led to an increase in the size of the wound defect and loss of soft tissues due to their purulent melting. Complex surgical treatment aimed at eliminating surgical infection and transferring the wound process to the regeneration phase included repeated surgical treatments and the use of modern dressings and negative pressure therapy. An extensive wound defect of soft tissues caused by and injury or surgical treatment for purulent–necrotic complication was found in the functionally active zone of the hip joint and in the sacral region, which required the restoration of the skin of these areas. A strategy for surgical repair of a soft tissue wound defect is presented. Nonfree (rotated) blood-supply flaps were used: fasciocutaneous muscle flap based on the musculus tensor fascia lata from the right thigh and gluteal fasciocutaneous flap from the left gluteal region. After multistage surgical treatment, it was possible to replace an extensive wound defect of soft tissues and restore full skin in the hip joint and sacrogluteal region, which enabled avoiding trophic disorders and joint contractures and ensured a satisfactory cosmetic and functional result during 5-year followup.

Dextran-Based Antibacterial Hydrogel Dressings for Accelerating Infected Wound Healing by Reducing Inflammation Levels.

Infected wounds pose challenges such as exudate management, bacterial infections, and persistent inflammation, making them a significant challenge for modern dressings. To address these issues in infected wounds more effectively, aerogel-hydrogel biphase gels based on dextran are developed. The gel introduced in this study exhibits antibacterial and anti-inflammatory properties in the process of wound therapy, contributing to accelerated wound healing. The aerogel phase exhibits exceptional water-absorption capabilities, rapidly soaking up exudate from infected wound, thereby fostering a clean and hygienic wound healing microenvironment. Concurrently, the aerogel phase is enriched with hydrogen sulfide donors. Following water absorption and the formation of the hydrogel phase, it enables the sustained release of hydrogen sulfide around the wound sites. The experiments confirm that hydrogen sulfide, by promoting M2 macrophage differentiation and reducing the levels of inflammatory factors, effectively diminishes local inflammation levels at the wound site. Furthermore, the sodium copper chlorophyllin component within the hydrogel phase demonstrates effective antibacterial properties through photodynamic antimicrobial therapy, providing a viable solution to wound infection challenges.

The Effect of Ozone Therapy Stimulation on Diabetes Wound Healing Process

<p>Health problems that are currently developing include diabetes mellitus (DM) with various complications including diabetic ulcers. Diabetic ulcers are the main cause of prolonged pain and even amputation in DM patients. Diabetic wounds are a complication of diabetes that often occurs in the extremities, increasing morbidity and lessens the patient's personal satisfaction. Ozone therapy is one method used to speed up the healing process for diabetic ulcers. This study plans to examine the impact of ozone treatment feeling on diabetic injury mending. The exploration strategy utilizes a semi exploratory technique with a pretest and posttest non-identical benchmark group plan. The testing strategy is a non-likelihood inspecting method.The population in this study were all patients suffering from diabetic wounds who received wound care at the Edwcare clinic in Langsa city. The respondents of this study were patients suffering from diabetic wounds who received wound care at the Edwacare wound care center in Langsa City, Indonesia consisting of 28 respondents who received modern wound care dressings and 28 respondents received wound care combined with modern dressings and ozone therapy. The research instrument for assessing wound severity used the Bates-Jensen Wound Assessment Tool. Data analysis used the Friedman and Kruskal Wallis tests. Based on the research results, it was found that there was a more significant effect between wound care using a combination of modern dressings and ozone therapy with a Mean Rank value of 39.75 compared to wound care that only received modern dressing wound care with a Mean Rank value of 17.25 with a value of p -value <0.05. The conclusion is that the effect of ozone stimulation significantly influences the healing process of diabetic wounds and is recommended as a nursing intervention that can be applied in treating diabetic wounds.</p><p><strong><em>Keywords: Diabetes mellitus, diabetic wounds, ozone therapy, stimulation</em></strong></p>

Description Of Diabetic Wound Treatment With Hydrogel In Pedis Care Malang City

The hydrogel's optimum hydration ability can lyse slough and necrotic tissue (autolytic debridement ability). This study aims to determine the description of diabetic wound care using hydrogel as a modern dressing in the development of BWAT scores. The research design uses a case study method and consisting of 2 samples with grade II-III diabetic ulcers at Pedis Care Malang. The results of the study on subject I obtained the BWAT score on the first treatment was 33 and on the sixth day of treatment was 26, in subject II the first treatment was 37 and on the sixth day of treatment was 25, showed a decrease in the BWAT score, which means that diabetic ulcer healing progressed. The healing process of diabetic ulcer wounds is also influenced by the nutrients that enter the body, one of which is protein which plays a role in cell formation. The researcher's advice for both subjects is that they are expected to be able to maintain wound moisture with sustainable modern dressings until the wound is declared healed and increase nutrition as a supporting factor for wound healing.

Caring for Patients With Malignant Fungating Wounds: A Scoping Literature Review.

The aim of this scoping literature review was to identify current knowledge related to management of malignant fungating wounds (MFWs), gaps in this knowledge, and areas for future research. This was a scoping literature review. Six electronic databases (Embase, MEDLINE, Cochrane (CENTRAL), CINAHL, Scopus, and Web of Science) were searched spanning the years 1987 and 2022. The initial electronic database search retrieved 6041 studies. The search is based on 60 articles published between 1987 and 2022, along with 14 additional studies were based on search of reference lists of key articles. Studies were divided into 2 main domains; the vast majority (65 of 72, 87.8%) focused on symptom impact, measurement, and management. The remaining articles (n = 9, 12.2%) focused on caring for patients with MFW; these studies focused on nursing care experiences and competencies, along with lay caregiver experiences. Findings indicated that instruments have been developed to evaluate symptoms of MFW but only a few have been validated. Most of the studies reviewed evaluated the influence of MFW on physical and psychosocial function. Local and systematic symptom managements such as modern dressings, wound care strategies, surgery, and radiotherapy as well as chemotherapy were found to be effective in alleviating symptoms. Findings also indicated that families and nurses encounter obstacles and burdens when caring for patients with MFW; limited studies were retrieved that investigated the competence and needs of nurses in their caring journey. Future studies should focus on: (1) using better designs to evaluate and compare topical agents and dressings to control odor, (2) validating assessment tools specific to MFW, (3) qualitative studies designed to enhance understanding family and nurses' experiences, and (4) improving the nurse's ability to care for patients with MFWs and their responses to managing these challenging patients.

Reconfiguring the endogenous electric field of a wound through a conductive hydrogel for effective exudate management to enhance skin wound healing.

The ionic environment has a strong influence on the bioelectricity of skin, which is also present in the wound healing process. Inspired by this, we proposed a mechanism for hydrogel-based dressings to respond to endogenous electric fields through exudate absorption and conducted a verification study using a typical hydrogel, namely, polyacrylamide and sodium alginate (PAM-SA) hydrogels, as an example. Theoretical calculations showed that the PAM-SA hydrogels could absorb and orient the various electrolytes of exudate in the hydrogel at the wound site, contributing to the reconstruction of the electric field at the wound site. During the treatment process, this effect significantly accelerated the healing process of the rat epidermis, which exceeded the conventional dressing in terms of healing speed and efficacy, and the wounds on the complete layer of rat skin (wound area: 1.13 cm2) could be rapidly repaired within 10 days. Revealing the electrophysiological behavior of PAM-SA dressings during wound healing can help further improve the design model, the optimization concept, and development paths for the bioelectrical structures of modern dressings and bioelectrical stimulation in wound healing.

Combination of polylactide with cellulose for biomedical applications: a recent overview

AbstractThis review summarizes the use of cellulose and polylactide for medical applications with particular emphasis on modern dressings. Although classic cotton and viscose dressings are still available and popular, the usefulness of new forms of cellulose (Cel) and its derivatives opens new wound treatment options. Therefore, trends in functionalizing traditional cellulose dressings, including products made of bacterial cellulose, and dressings from cellulose derivatives, are discussed. Polylactide (PLA), in turn, is a biodegradable and biocompatible polyester that fulfills plenty of tasks in many medical fields, from surgery to modern diagnostic methods. However, polylactide dressings can still be advantageous to the market. Thus, the next part of the article contains a recent update of available knowledge about PLA and its applications in regenerative medicine and drug-delivery systems. The last part is devoted to the possibilities of combining both materials in dressings and related problems and benefits. Methods for compatibilization with the surface of both polymers and new techniques for producing Cel/PLA composite materials are also described.

Family Empowerment Method Modern Dressing Based to Increase Diabtes Mellitus Patients with Diabetic Ulcer

Diabetic ulcer is lower extremity illness in diabetic patients with sensory, motoric, autonomic neuropathy, and or limbs blood vessel disorder as the characteristics. Patients with diabetic ulcer often experience psychological stress as the result of the infection of the ulcer itself or the operation procedure, thus negatively affects patients’ self-concept, self-worth, quality of life, physiological and psychological health, hope to recover, and their spirituality. This research aimed to recognize the effect of family empowerment method modern dressing based in inflating diabetic ulcer patients’ quality of life. This research utilized pre-experimental with one group pretest-posttest design. The population and sample in this research are diabetic ulcer patients. The sampling technique used was purposive sampling with the total of 53 respondents. The instrument used was WHOQOL (The World Health Organization of Quality of Life). The research found that patient’s QoL before family empowerment was given, the moderate QoL (Quality of Life) was 41 respondents (77.4%) and the good QoL was 12 respondents (22.6%). After the treatment using the aforementioned method, the good QoL increased to 28 respondents (52.8%), the moderate QoL became 7 respondents (13.2%) and the very good QoL increased as much as 18 respondents (34%). Wilcoxon analysis test resulted ρ 0,000, meaning that there was an effect of family empowerment method modern dressing based to patients with diabetic ulcer

Insight into Topical Preparations for Wound Healing: Traditional and Modern Dressings

Insight into Topical Preparations for Wound Healing: Traditional and Modern Dressings

Effectiveness of Modern Dressing on Healing Diabetic Foot Ulcer: A Literature Review

Background: Diabetes mellitus is a group of heterogeneous disorders that have indications in the form of increased content of high blood sugar levels. WHO also confirmed DM to be the 7th trigger of death. IDF (International Diabet Federation) data estimates from survey results after North America in 2017 the 3rd place was occupied by Southeast Asia and people with diabetes mellitus with a percentage of 8.5% at the age of 20-29 years in North Africa. One of the treatments for patients with diabetes mellitus can be wound care using Modern Dressing with the Moist Wound Healing method. Methods: The method used in this wound treatment is the Modern Dressing technique with the Moist Wound Healing method. This procedure can clinically grow tissue 30-50%, increase collagen synthesis by 50%, and the rate of re-epithelialization with moist conditions is 2-5 times faster and can reduce the amount of fluid from above the wound surface. Results: evaluation shows that Modern Dressing wound care with the Moist Wound Healing method is in fact able to maintain moist conditions in the wound, reduce inflammation in the wound so that it can improve and accelerate the healing process of diabetic ulcers. Conclusion: The results showed that the Modern Dressing technique with the Moist Wound Healing method was able to improve the healing process of diabetic ulcers. The results also showed that there were significant changes between modern and conventional dressings. The modern dressing group had a much better development than the conventional dressing. The application of the Moist Wound Healing method in patients with diabetic ulcers can provide a much faster wound recovery reaction.

Potential of Honey Hydrogel Modern Dressing in Wound Healing of Patients with Grade II Diabetic Foot Ulcer

Aims: To analyze the potential of honey hydrogel modern dressing in wound healing process in patients with grade II diabetic ulcers. Methods: The research design used a true experiment with a randomized pretest posttestcontrol group design. This study had 36 respondents who were divided into 2 groupsthrough simple random sampling. The intervention group was given honey hydrogel with 4measurements. The first measurement or pretest on day 1, the second measurement orposttest 1 on day 7, the third measurement or posttest 2 on day 14, and the fourthmeasurement or posttest 3 on day 21. The instrument used to measure patient woundhealing using the Bates-Jensen Wound Assessment Tool (BWAT). Results: The increase in the mean wound healing score of patients who were given honeyhydrogel modern dressing from a score of 42.11 on day 1 to 34.56 on day 21 with p = 0.001while the increase in the mean wound healing score of patients who were givenmanufacturer hydrogel modern dressing from a score of 41.67 on day 1 to 37.17 on day 21with p = 0.001. The effect size between the intervention group and the control group is quitestrong with a value of 0.78. Conclusion: Honey hydrogel has the potential to promote wound healing in patients withgrade II diabetic ulcers. Further research is recommended to explore the use of honeyhydrogel by innovating the manufacturing process to ensure consistent dosing in thetreatment of grade II diabetic ulcers.

Modern Dressings for the Treatment of Chronic Wounds and the Family Doctor - Case Reports

The appearance of modern dressings for the treatment of chronic wounds with the concept of moist wound healing has brought a completely new doctrine of their treatment, enabling significantly faster healing and thus a number of other benefits for health systems and health workers, patients with chronic wounds, and for society as a whole, reducing treatment costs drastically. The greatest benefit from their use is achieved by patients with chronic wounds, bearing in mind that a chronic wound significantly reduces and impairs the quality of life of patients. What makes modern dressings for the treatment of chronic wounds special is their simple use, which enables even family doctors to successfully treat chronic wounds with modern dressings, when the location of the wound itself and the involvement of frozen tissue allow it. They can be applied in the doctor's offices as well as in the patients' homes by the patrol services. Their application can be of particular importance to patients in rural areas where the health care system is more difficult to access and where the appointments of health workers, doctors and nurses are not daily. In those cases, patients, as well as their family members, can be educated to apply modern dressings for the treatment of chronic wounds by themselves with occasional control examinations by health workers.

Особенности сердечно-сосудистых нарушений у больных диабетической стопой

The purpose — to improve the effectiveness of treatment of diabetic foot patients with cardiovascular disorders. Material and methods. 782 patients with diabetic foot (DF) were under observation. 4 groups were identified: group 1 — VAC therapy was used; group 2 — ultrasonic cavitation; group 3 — modern dressings were used for treatment; group 4 — with a standard treatment. Low doses of statins were used (atorvastatin 10–20 mg/day or rosuvastatin 5–10 mg/day) in 213 patients (27.2%) and 89 patients (11.4%) received moderate or high doses of statins (atorvastatin 40–80 mg/day or rosuvastatin 20 mg/day) in combination with ursodeoxycholic acid (UDCA) preparations (750–1750 mg/day). Results. In the low-dose statin subgroup, the rate of low-density lipoprotein cholesterol levels reduction averaged 17.6 (5.6) % of the initial values; triglycerides, respectively, 12.3 (3.5) % of the initial values; that was statistically significantly lower than in the moderate/high dose statin plus UDCA subgroup of 32.9 (5.4) % and 18.7 (3.2) %, respectively, all p<0.001. In group 1, the average duration of hospital stay and the percentage of postoperative complications were statistically significantly lower in patients who received lipid-lowering therapy (28.5 (3.6) days and 8.8 (2.9) %), compared with those who did not receive this treatment (34.0 (2.8) days and 13.1 (2.6) %); p < 0.001. Similar differences in the length of hospital stay and the percentage of postoperative complications, depending on the lipid-lowering therapy, also occurred in groups 2, 3, and 4 (p < 0.001). Conclusions. The use of lipid-lowering therapy, including moderate / high doses of statins in combination with UDCA, contributed to a decrease in the length of hospital stay and a decrease in the incidence of postoperative complications in all groups of patients with DF.

Biomedical materials for wound dressing: recent advances and applications.

Wound healing is vital to maintain the physiological functions of the skin. The most common treatment is the use of a dressing to cover the wound and reduce infection risk and the rate of secondary injuries. Modern wound dressings have been the top priority choice for healing various types of wounds owing to their outstanding biocompatibility and biodegradability. In addition, they also maintain temperature and a moist environment, aid in pain relief, and improve hypoxic environments to stimulate wound healing. Due to the different types of wounds, as well as the variety of advanced wound dressing products, this review will provide information on the clinical characteristics of the wound, the properties of common modern dressings, and the in vitro, in vivo as well as the clinical trials on their effectiveness. The most popular types commonly used in producing modern dressings are hydrogels, hydrocolloids, alginates, foams, and films. In addition, the review also presents the polymer materials for dressing applications as well as the trend of developing these current modern dressings to maximize their function and create ideal dressings. The last is the discussion about dressing selection in wound treatment and an estimate of the current development tendency of new materials for wound healing dressings.

Современные взгляды на проблему местного лечения ожоговых ран

The issues of modern tactics of burn wounds local treatment using various medications and temporarywound coverings were reviewed by the authors. Despite a variety of modern dressings for local treatmentof burn wounds, the specialists are not yet fully satisfied with results. The development and widespreadintroduction into clinical practice, contribute to the improvement of treatment results in this category ofpatients. The use of temporary wound coverings reduces the recovery process, being the most physiologically acceptable coverings of the wound burn surface, achieving their main goal – early formation ofgranulation tissue, reduction of secondary inflammatory processes. The effectiveness of local treatmentof burn wounds depends on the timely and correct choice of drugs depending on the phase of the woundprocess.

The use of modern dressings after complex treatment of malignant tumors of the maxillofacial region

The use of modern dressings after complex treatment of malignant tumors of the maxillofacial region

In Vitro and In Vivo Characterization Methods for Evaluation of Modern Wound Dressings.

Chronic wound management represents a major challenge in the healthcare sector owing to its delayed wound-healing process progression and huge financial burden. In this regard, wound dressings provide an appropriate platform for facilitating wound healing for several decades. However, adherent traditional wound dressings do not provide effective wound healing for highly exudating chronic wounds and need the development of newer and innovative wound dressings to facilitate accelerated wound healing. In addition, these dressings need frequent changing, resulting in more pain and discomfort. In order to overcome these issues, a wide range of affordable and innovative modern wound dressings have been developed and explored recently to accelerate and improve the wound healing process. However, a comprehensive understanding of various in vitro and in vivo characterization methods being utilized for the evaluation of different modern wound dressings is lacking. In this context, an overview of modern dressings and their complete in vitro and in vivo characterization methods for wound healing assessment is provided in this review. Herein, various emerging modern wound dressings with advantages and challenges have also been reviewed. Furthermore, different in vitro wound healing assays and in vivo wound models being utilized for the evaluation of wound healing progression and wound healing rate using wound dressings are discussed in detail. Finally, a summary of modern wound dressings with challenges and the future outlook is highlighted.