Moderate Compliance Research Articles

Using Biosensor Devices and Ecological Momentary Assessment to Measure Emotion Regulation Processes: Pilot Observational Study With Dialectical Behavior Therapy.

Novel technologies, such as ecological momentary assessment (EMA) and wearable biosensor wristwatches, are increasingly being used to assess outcomes and mechanisms of change in psychological treatments. However, there is still a dearth of information on the feasibility and acceptability of these technologies and whether they can be reliably used to measure variables of interest. Our objectives were to assess the feasibility and acceptability of incorporating these technologies into dialectical behavior therapy and conduct a pilot evaluation of whether these technologies can be used to assess emotion regulation processes and associated problems over the course of treatment. A total of 20 adults with borderline personality disorder were enrolled in a 6-month course of dialectical behavior therapy. For 1 week out of every treatment month, participants were asked to complete EMA 6 times a day and to wear a biosensor watch. Each EMA assessment included measures of several negative affect and suicidal thinking, among other items. We used multilevel correlations to assess the contemporaneous association between electrodermal activity and 11 negative emotional states reported via EMA. A multilevel regression was conducted in which changes in composite ratings of suicidal thinking were regressed onto changes in negative affect. On average, participants completed 54.39% (SD 33.1%) of all EMA (range 4.7%-92.4%). They also wore the device for an average of 9.52 (SD 6.47) hours per day and for 92.6% of all days. Importantly, no associations were found between emotional state and electrodermal activity, whether examining a composite of all high-arousal negative emotions or individual emotional states (within-person r ranged from -0.026 to -0.109). Smaller changes in negative affect composite scores were associated with greater suicidal thinking ratings at the subsequent timepoint, beyond the effect of suicidal thinking at the initial timepoint. Results indicated moderate overall compliance with EMA and wearing the watch; however, there was no concurrence between EMA and wristwatch data on emotions. This pilot study raises questions about the reliability and validity of these technologies incorporated into treatment studies to evaluate emotion regulation mechanisms.

Impact of a care bundle on short peripheral catheter-associated complications in a resource-limited neonatal unit.

Short peripheral catheter (SPC)-associated complications occur frequently in hospitalised neonates. Few studies have reported the use of SPC care bundles in resource-limited neonatal units. To evaluate the impact of a SPC care bundle on SPC associated complications (infiltration, dislodgement, phlebitis) and catheter dwell time. We conducted a quasi-experimental study comparing neonatal SPC complications during a 2-month baseline and a 2-month intervention period, where a SPC care bundle was introduced including hand hygiene, insertion site antisepsis, nurse assistance during cannulation, IV insertion carts and IV securement dressings. A total of 459 SPC days were observed in 223 neonates: 111 pre-intervention and 112 post-intervention (after SPC bundle implementation). Most neonates were preterm (208, 93.3%) with very or extremely low birth weight (133, 59.6%). SPC care bundle compliance was 43.8% for five bundle elements and 83.9% for four bundle elements. Most SPCs had unplanned removal within 48 h of insertion owing to infiltration or dislodgement (89/111 pre-intervention (80.2%) vs 90/112 post-intervention (80.4%); 0.974). No phlebitis was documented. The mean SPC dwell time was unchanged following bundle implementation (32.9 vs 34.2 h; p = 0.376). Infiltration and dislodgement occurred frequently necessitating replacement of four of every five SPCs. Despite moderate compliance with the SPC care bundle, the high rates of unplanned SPC removal and short duration of catheter dwell time were unchanged. The SPC care bundle did not improve catheter dwell time; further research is needed to identify strategies to reduce unplanned SPC removal and extend catheter dwell time in hospitalised neonates.

Hubungan Usia dengan Kepatuhan Minum Obatantihipertensi di Puskesmas Tanjung Pinang Kota Jambi Tahun 2024

Hypertension is one of the most common diseases in Indonesia. If this disease is not treated properly, it can cause complications of other diseases. To avoid these complications, patients must take drugs correctly in their treatment. One of the factors that affect the treatment of hypertension is compliance in taking antihypertensive drugs. The purpose of this study was to determine the relationship between age group and adherence to taking antihypertensive medication at the Tanjung Pinang Health Center, Jambi City in 2024. This study used a cross sectional method using the MMAS-8 (Morisky Adherence Scale) questionnaire instrument by taking a sample of hypertensive patients in the elderly category who were patients referred back to the Tanjung Pinang Health Center. Primary data by distributing questionnaires to patients who seek treatment. The population in this study amounted to 347 elderly hypertensive patients. Sampling using purposive sampling. With a sample of 78 respondents. The results were obtained based on the percentage of low compliance as many as 32 respondents (41.0%), moderate compliance as many as 27 respondents (34.6%) and the high compliance category as many as 19 respondents (24.4%). For the age category in the early elderly with moderate compliance as many as 14 respondents (53.8%), late elderly high compliance as many as 7 respondents (26.9%) and seniors low compliance as many as 17 respondents (6.4%). Based on the chi square test that has been carried out, the p value is 0.011 <0.05, which indicates that there is a significant relationship between age and compliance with taking antihypertensive drugs at the Tanjung Pinang Health Center, Jambi City in 2024. To improve compliance in taking medication, it is hoped that health workers can increase the provision of health education, counseling, motivation and encouragement to people with hypertension to always be obedient in taking medication and managing a healthy lifestyle for their recovery.

Evaluation of the quality of platelet concentrates obtained in a Peruvian hospital.

Platelet concentrates are blood products obtained from donor's blood, and their conservation must be subject to a strict quality control process to guarantee a safe and high-performance product in treating diseases that require their use. We designed a cross-sectional study to determine the total compliance rate in platelet concentrates obtained in the blood bank of the Cayetano Heredia Hospital in Lima during November and December of 2019. The Buffy method Coat obtained the platelet concentrates, and parameters such as platelet count and residual leukocytes, pH, and swirling effect were evaluated according to the National Hemotherapy and Blood Bank Program criteria. The platelet count had a mean of 6.66 ± 3.94 x 10¹⁰/µL, the platelet concentrates had a mean of 56.30 ± 6.22 mL, and all, without exception, had the presence of the Swirling phenomenon. The pH had a mean of 7.64 ± 0.15, while the leukocyte count had a mean of 4.22 ± 3.51 x 10⁷/µL. Regarding compliance by the parameters evaluated, it was evident that the platelet and leukocyte count had moderate compliance rates of 43.6% and 24.1%, while the pH and swirling effect had rates of 100% in both cases. The total compliance rate was 54.9% (95% confidence interval: 46.0 to 63.5). The compliance rate of platelet concentrates is moderate, and it is necessary to implement a process of continuous quality improvement in the blood bank.

The 11+ injury prevention programme decreases rate of hamstring strain injuries in male collegiate soccer players

ObjectivesTo investigate if the 11+ injury prevention programme decreases the risk of hamstring injury and improves recovery time and determine whether compliance with the 11+ affects hamstring injury risk.MethodsThis study...

Infection Control Attitude, Knowledge and Awareness Level Among Dental Students and Interns in the Removable Prosthodontic Department at the Faculty of Dentistry, University of Benghazi, Libya

Background: Dental students have increased patient contact during their education and clinical practice, putting them, their patient population and Dental Health Care Workers (DHCW) at high risk of cross-infection. Awareness of infection control principles may help in preventing disease transmission; therefore, the purpose of this study was to evaluate the level of infection control knowledge, attitude, and practice among dental students and interns in a removable prosthodontic department at the Faculty of Dentistry, University of Benghazi, Libya. Materials and Methods: In May 2023, we distributed questionnaires containing 33 items to interns, 3rd-year, and 4th-year dental students at the faculty. The questions covered topics such as hepatitis B vaccination, use of personal protective barriers, knowledge of infection control protocols, and practice in the removable prosthodontic department of the faculty. Descriptive statistics were recorded using frequency and percentages. Differences in proportions were assessed using the Chi-square and Fisher exact test. All statistical analyses were performed at a p-value less than 0.05. Results: A total of four hundred and ten (410) participants responded to the questionnaire. Around 21.5% of the students had completed their hepatitis B vaccination, while 41.2% had never been vaccinated. Regarding the self-reported use of protective barriers, intern students showed a significantly higher score than did other study groups (P <0.001). Moreover, the vast majority of 3rd year students reported never wearing eyewear, a face shield, or the head cap (73.2%), (81.1%), or (70.1%), respectively. About two-thirds of intern students (69.4%) showed positive attitudes toward the treatment of patients with infectious diseases. Conclusion: This study showed moderate compliance to infection control procedures among the participants, they have limited orientation and knowledge of the infection control guidelines and policies. Despite a positive attitude toward infection control measures, proper infection control practices were not consistently followed. Consequently, it is essential to take action to ensure that students understand the critical importance of practicing cross-infection control. Higher education institutions should implement effective solutions to address this issue.

Understanding the impact of HIV on mpox transmission in the MSM population: A mathematical modeling study

The recent mpox outbreak (in 2022–2023) has different clinical and epidemiological features compared with previous outbreaks of the disease. During this outbreak, sexual contact was believed to be the primary transmission route of the disease. In addition, the community of men having sex with men (MSM) was disproportionately affected by the outbreak. This population is also disproportionately affected by HIV infection. Given that both diseases can be transmitted sexually, the endemicity of HIV, and the high sexual behavior associated with the MSM community, it is essential to understand the effect of the two diseases spreading simultaneously in an MSM population. Particularly, we aim to understand the potential effects of HIV on an mpox outbreak in the MSM population. We develop a mechanistic mathematical model of HIV and mpox co-infection. Our model incorporates the dynamics of both diseases and considers HIV treatment with anti-retroviral therapy (ART). In addition, we consider a potential scenario where HIV infection increases susceptibility to mpox, and investigate the potential impact of this mechanism on mpox dynamics. Our analysis shows that HIV can facilitate the spread of mpox in an MSM population, and that HIV treatment with ART may not be sufficient to control the spread of mpox in the population. However, we showed that a moderate use of condoms or reduction in sexual contact in the population combined with ART is beneficial in controlling mpox transmission. Based on our analysis, it is evident that effective control of HIV, specifically through substantial ART use, moderate condom compliance, and reduction in sexual contact, is imperative for curtailing the transmission of mpox in an MSM population and mitigating the compounding impact of these intertwined epidemics.

COMPLIANCE OF HOSPITAL HEALTHCARE PROFESSIONALS WITH CONTACT LENS USE AND CARE

Objective: The study aimed to assess if healthcare professionals who wear contact lenses in hospitals comply with the rules for contact lenses use and care. Material and Methods: A survey consisting of questions about contact lenses use and care was distributed to healthcare professionals. The survey investigated the following: a) Demographic data, b) Routines related to the use of contact lenses (type, indication, duration, overnight use), c) Routines related to contact lenses maintenance and cleaning (solution usage habit, exposure to water, hygiene of hands and lens cases). Results: The average age of the participants was 28.35±5.58; 76% were women, and 87.3% were doctors. Contact lenses usage duration was 8.16 years. Most of them wore soft contact lenses for myopia that was changed monthly. 95.8% of participants were prescribed contact lenses by an ophthalmologist. To clean the contact lenses, 93.3% of the participants used multi-purpose solutions, and 7.3% reported that they rarely washed the contact lenses with tap water. A high level of compliance was observed with overnight use, washing hands before putting on and taking off contact lenses, expiration date, and filling the solution into the box or sharing it. Moderate compliance rates were noted for swimming and showering with contact lenses, cleaning, and changing the lens case and contact lenses. Conclusion: Although healthcare professionals are compliant with the use and care of the contact lenses, it is thought that some of them still need training on avoiding contact with water while wearing the contact lenses, never using tap water, and cleaning the lens case and the contact lenses effectively.

Educating patients about health helps slow the progression of chronic kidney disease in the eastern region of India

Abstract Background: Chronic kidney disease (CKD) poses a well-documented burden, necessitating patient awareness of the importance of healthy lifestyle modifications to mitigate co-morbidities and mortality risks. Objective: This study aimed to assess the effectiveness of education-based conservative management in mitigating disease progression among CKD patients in the eastern region of India. Materials and Methods: A total of 248 CKD patients receiving outpatient department and inpatient department care at the nephrology and dialysis department of Belle Vue Clinic, Kolkata, West Bengal, India, were included in the study. Comprehensive data encompassing demographic details, socioeconomic status, clinical co-morbidities, and conservative management interventions via patient education were examined. The study compared the rise in creatinine levels with adherence to five key factors: dietary restrictions, medication compliance, follow-up appointments with physicians, management of co-morbidities, and adherence to lifestyle modifications. Each strategy was graded on a scale of 0, 1, or 2 based on compliance, with 0 indicating minimal or no compliance, 1 indicating moderate compliance, and 2 indicating strong compliance. Results: In this study, several factors were linked to elevated creatinine levels among CKD patients, including being in the middle-age range, male gender, living predominantly in urban areas, and working in business or service occupations. Additionally, a higher prevalence of co-existing conditions such as diabetes mellitus and hypertension was noted among CKD patients, along with documented instances of polycystic kidney disease, obstructive uropathy, and renal cell carcinoma. After educating CKD patients, those who scored 8–10 on compliance exhibited a decrease in creatinine elevation (0.35 mg/dL) among 120 cases from January 2022 to June 2023. Conversely, those with scores ranging from 5 to 7 (81 cases) showed moderate creatinine elevation (1.24 mg/dL), while those with scores of 0–4 (47 cases) demonstrated higher levels of creatinine elevation (5.48 mg/dL). Conclusion: This study concludes that the conservative management of CKD patients educates individuals about primary prevention of the disorder and provides a comprehensive understanding of secondary and tertiary prevention strategies. This cost-effective approach significantly impacts physical, mental, social, and psychological adjustment behaviors.

The factors influencing compliance in post-EVAR surveillance regarding the perspectives of practitioners and patients

Aim: Lifelong monitoring is essential to detect aorta-related complications. Yet, patient non-compliance with surveillance programs poses a significant obstacle. We explored reasons for adherence by engaging in clear, patient-centred communication and analyzed factors contributing to non-compliance. Material and Methods: In 2019, our clinic conducted elective EVAR procedures on 50 patients. They were informed of annual surveillance, including hospital visits, starting with a first-month appointment post-discharge. Patients with no or only one follow-up were deemed non-compliant, while two to three follow-ups indicated moderate compliance, and four to seven follow-ups qualified as high compliance. We recorded each patient's age, education level and demographics. We retrospectively assessed the factors on their compliance level as our first outcome. The second was to explore whether the survey could enlighten any reasons from the patient's perspective. Results: The average age of our cohort was 68.8±8.45 years, with only three females. Non-attendance at follow-ups was observed in 8 patients (16%). Seventy percent (35 patients) complied with at least two appointments. Residing in the same city markedly increased compliance by 20 times (p<0.001). Older age appeared to influence compliance positively, on the borderline significantly (p=0.057). The primary motivation for attendance was adherence to doctor recommendations (n=14), while the predominant reason for non-attendance was patients’ feeling well (n=29). Notably, patients with lower compliance than predicted more frequently cited COVID-19 as a deterrent (p=0.02). Conclusion: Residence within the same city positively influences follow-up compliance. The national databases might be helpful tools for enhancing the surveillance anywhere the patients live. The existing hypotheses by healthcare professionals about patient follow-up compliance are only partially corroborated. Incorporating the patient's perspective into these models may be helpful in comprehensively understanding the underlying factors.

A Study to Assess the Compliance Regarding Self Care Management among Type-2 Diabetes Mellites Patient at Selected Area of Dadra and Nagar Haveli

ABSTRACT : Introduction: Diabetes is a chronic disease that can be self-managed and control the disease and its adverse consequence. Diabetes is an important public health problem of India. studies have shown that increase in patients’ knowledge regarding the disease result in better compliance. The prevalence of diabetes is predicted to double globally from 171 million in 2000 to 366 million in 2030 with a maximum increase in India. Aim: The aim of the study was to assess the compliance regarding self-care management of among type-2 diabetes mellites patient at selected area of Dadra and Nagar haveli. Method : This in study quantitative descriptive research design was used. A total 100 respondent who met the sampling criteria were selected by purposive sampling technique. The data were collected using self-Questionnaire on compliance. Result: Result showed that 63% had moderate compliance on self-care management whereas only 37% had good compliance among patient with type-2 DM. Conclusion: The study concluded that the assessment of the compliance on self-care management among Type-2 DM need to be addressed. Keywords: Assess, compliance, self-care management, type-2 DM.

Policing during a pandemic: A case study analysis of body-worn camera footage from suspected COVID-19 ordinance violations in Washington state

PurposeThis research examined interactions between police officers and those suspected of violating COVID-19 ordinances. It explored the interactional nature of these encounters and how participants navigate these ordinance violations to more effectively develop methods to improve compliance during future pandemics. Additionally, this research addressed a methodological gap by describing and utilizing an innovative method to analyze body-worn camera (BWC) footage. This case study uses BWC footage derived from a police agency in Washington state. MethodsUsing a population of 136 interactions involving suspected violations of COVID-19 ordinance violations between March 2020 and November 2020, this study uses convergent holistic triangulation within a mixed-method research design to extract data for quantitative analysis paired with qualitative analysis of transcripts and BWC footage. ResultsFindings highlight several interesting, previously unexplored details regarding police and suspected violators’ behavior during the pandemic. Results suggest moderate officer compliance with PPE mandates; officers justified the ordinance in less than a third of COVID-19-related interactions, issued citations in a quarter of interactions, and made minimizing statements towards COVID-19 ordinances in a quarter of interactions. ConclusionsUsing convergent holistic triangulation, results reveal how the officer(s) and the party(s) of interest navigated the conversation with a detailed analysis of responsibility, neutralization, focal concerns, and deconstruction of each event. Central to the findings is accurate, clear, concise, and consistent communication. The variability observed in how responding officers managed scenes demonstrates a need to augment communication between and within relevant institutions. Implications of this study include increased preparedness for police agencies in crisis management, particularly as it relates to community interactions.

Analisis Faktor Yang Mempengaruhi Kejadian Fraud Pada Organisasi Perangkat Daerah Kabupaten Manggarai

Background - Fraud is an interesting issue to discuss and it is necessary to study cases that often occur in organizational management areas such as regional apparatus organizations. Some Fraud cases occur in Indonesia due to failures in the accountability process of the government such as failed leadership styles, inappropriate compensation and individual morality. Objective - To examine the effect of leadership style, compensation suitability and individual morality on Fraud in Regional Apparatus Organizations in Manggarai Regency, East Nusa Tenggara (NTT). Design / Methodology / Approach - Using quantitative methods with a questionnaire distributed to 100 employees from 20 OPDs in Manggarai Regency, who are authorized to use the budget as respondents who are eligible to be sampled. The sampling technique in this study used purposive sampling technique with the data analysis method used was path analysis with the sobel test processed by SPSS version 26. Results and Discussion - Individual behavior, leadership style, suitability of compensation, and individual morality have no influence on unethical behavior, while compliance with financial rules influences unethical behavior. Leadership style, suitability of compensation, individual morality and compliance with financial regulations have no effect on the occurrence of Fraud, while internal control has a negative effect on Fraud. Unethical behavior is able to moderate internal control variables, individual morality, and compliance with financial regulations regarding Fraud incidents. Conclusion - The unethical behavior variable can be an intervening variable in the occurrence of Fraud in the Manggarai OPD. The Manggarai Regency Government is expected to be able to prevent Fraud by considering the influencing factors and factors that mediate the occurrence of Fraud. Research limitations - Has several limitations, namely that it was only carried out on 20 OPDs in Manggarai Regency, NTT, so that it cannot be generalized to a wider area.

Compliance with the WCRF/AICR Recommendations in Qualitative Adaptation and the Occurrence of Breast Cancer: A Case-Control Study.

The aim of the study was twofold: (1) the qualitative adaptation of the 2018 WCRF/AICR (QAd-WCRF/AICR) score, and (2) the assessment of the association between the level of compliance with the WCRF/AICR recommendations and the occurrence of breast cancer in peri- and postmenopausal women. This case-control study involved 420 women, aged 40-79 years, from northeastern Poland, including 190 newly diagnosed breast cancer cases. Data related to the WCRF/AICR recommendations were collected in face-to-face interviews with 409 women, including 179 women with breast cancer. The frequency of food consumption data were collected using the FFQ-6® and KomPAN® questionnaires. Body weight, height, and waist circumference were measured. The QAd-WCRF/AICR score (range: 0-8 points) was calculated on the basis of eight components, including two components from to the WCRF/AICR recommendations: (1) body mass index (BMI), and (2) waist circumference, with six components expressed qualitatively: (3) overall physical activity, as well as the frequency of the consumption of (4) vegetables/fruits/whole grains/nuts/seeds/legumes, (5) highly processed foods, including fast foods/sweets/instant soups, (6) red/processed meat, (7) sweetened/energy drinks, and (8) alcohol. Logistic regression analysis was performed to assess the occurrence of breast cancer. The moderate (4-5 points) and maximal (6-8 points) compliance with the qualitative adaptation of the WRCF/AICR recommendations reduced the odds of breast cancer by 54% and 72%, respectively, compared to the results noted for minimal compliance (≤3 points). Lower odds of breast cancer were associated with moderate or high physical activity, consumption of a minimum of four serving per day of vegetables/fruits/whole grains/nuts/seeds/legumes, and limiting the consumption of highly processed food/fast foods and red/processed meat to a maximum of 1-3 times/month. Higher odds of breast cancer were associated with a higher waist circumference and alcohol abstinence. These findings may prove useful in establishing cancer prevention recommendations based on simple suggestions regarding the frequency of food consumption.

Tobacco Free Educational Institutions in India: TOWS Analysis

ABSTRACT Younger age has a greater likelihood of neurological vulnerability to nicotine initiation and addiction. Tobacco-Free Educational Institutions (ToFEI), guidelines are essential to promote a healthy learning environment for educational institutes. Better compliance with ToFEI guidelines leads to better implementation and enforcement for creating more positive and safe learning environment for student and staff. The need arises on identifying the potential areas of realistic engagement and action on tobacco use prevention among children using TWOS analysis of ToFEI guidelines in educational institutes. Moderate compliance has been achieved as far as ToFEI. TOWS analysis further enhances compliance in ToFEI by overcoming external factors (opportunity and threat) through its inherent internal factors (weakness and strength). Thus, clarity in strength and weakness of ToFEI guidelines will reduce vulnerability and susceptibility to threats by enhancing opportunities in ToFEI.

Association of chronic disease self-management with health locus of control study on diabetic patients

Aims: It was aimed at determining the relationship between chronic disease self-management and health locus of control in diabetic patients. Methods: Data were collected by the face-to-face survey method from diabetic patients over the age of 18 who were receiving inpatient treatment in a public hospital. Results: According to the research results; The total score average of the participants from the chronic disease self-management scale was moderate (mean: 64.11 Min: 21-Max: 105), w but treatment compliance (mean:15.81 Min:5-Max:25) ) was found to be at a medium level. The participants' internal locus of control score (mean: 25.08, Min: 9-Max: 36) was found to be higher than other sub-dimensions. As a result of the correlation analyses carried out; statistically significant relationships were obtained between chronic disease self-management total and sub-dimensions and health locus of control sub-dimensions. Conclusion: Statistically significant relationships were obtained between the chronic disease self-management total and sub-dimensions and the health locus of control sub-dimensions. It can be said that the participants have more internal locus of control beliefs.

Patient-centered health care planning in acute inpatient mental health settings: a best practice implementation project.

The current project aimed to improve the quality of health care by promoting evidence-based practice (EBP) regarding mental health care planning (MHCP) for adult inpatients. The implementation of the best evidence in the process of developing and documenting nursing care plans is currently an important legal requirement that contributes to increasing the quality of care. This implementation project was based on the JBI evidence implementation approach and included a baseline audit of seven criteria, implementation of strategies, and a follow-up audit. The project was conducted in an acute psychiatric setting at a university hospital in Bucharest, Romania. The sample included 17 nurses and 30 ward patients. The baseline audit revealed low compliance (33%-37%) for criterion 3 (a comprehensive care plan) and criterion 4 (patient involvement); moderate compliance (55%) for criterion 1 (care plan for all patients); and increased compliance (97%-100%) for criterion 2 (assessment of patient's needs), criterion 5 (education of patients/caregivers), criterion 6 (providing a copy at discharge), and criterion 7 (education of professionals). As a result of implementing the most appropriate strategies, the maximum improvement (100%) was observed across all five audit criteria that were found to be deficient in the baseline audit. The development and implementation of strategies adapted to specific care need to play a key role in the implementation of EBP. In this case, educating nurses, facilitating nurses' access to EBP for care planning, and improving procedures proved effective in achieving maximum compliance with all the audit criteria.

Abstract 201: 3D-Printed Automated Pressure-Cycled Resuscitator Maintains Respiratory Homeostasis in Swine With Normal to Moderately Low Lung Compliance

Background: During resuscitation, manual ventilation is commonly used. However, the effectiveness of this approach heavily relies on the skills of the individuals performing, often leading to inconsistent tidal volumes and respiratory rates. Such variations in ventilation can disrupt the removal of CO 2 resulting in altered pH. To address this problem, we leveraged advancements in fluidics and 3D printing to develop a miniature, automated, pressure-cycled resuscitator (inVent) that operates without any moving parts or settings. Hypothesis: The inVent will be able to maintain a pH of 7.2 or higher in swine with a dynamic compliance (Cdyn) of 25-50 ml/cmH 2 O. Goals/Aims: To assess the inVent’s performance in an animal model with normal to severe lung injury. Methods: Hybrid Landrace swine were studied under a protocol approved by the Institutional Animal Care and Use Committee. All swine were anesthetized, and underwent oral intubation. Breath by breath measurements were obtained using the NM3 Monitor (Phillips). All 3 inVent (fluidIQ) resuscitators pressure modules were used pre and post lung injury to fully characterize how each of the modules would react in different lung conditions. Lung injury was induced through a repeated bronchoalveolar lavage. ABG analysis was performed using the epoc system (Siemens). pH values 7.2 or less were considered acidotic while those over 7.2 were considered acceptable. Results: 8 swine with an average weight of 36 (5.8) Kg were studied. 7 swine contributed to 39,770 breaths of pulmonary mechanics and 33 ABGs recorded. Mean Cdyn was lower than anticipated at 25.8 (14.7) mL/cmH 2 O and a pH 7.32 (0.16). Figure 1 demonstrates a linear relationship with compliance and pH. Conclusions: The inVent resuscitator was able to maintain a pH of at least 7.2 in moderate compliance ranges, however struggled to maintain pH of 7.2 or higher in the severely injured. Higher lung compliance ranges are needed to explore possible hyperventilation events.

Compliance and satisfaction with treatment as a success of therapy effectiveness in the group of patients with ischemic heart disease: a cross-sectional study.

Non-adherence and non-compliance to pharmaceutical treatment is one of the most common causes of not effective management of patients suffering from ischemic heart disease (IHD). It is crucial to understand the reasons behind it but studies on this subject performed in the Polish population are still lacking. The 329 patients (160 male and 169 female) diagnosed with IHD who reported for follow-up appointments are examined. The following standardized questionnaires were used: Treatment Satisfaction with Medicines Questionnaire (SATMED-Q) and Adherence to Refills and Medication Scale (ARMS), which evaluates the patient's compliance and adherence level, respectively. Patients with IHD showed moderate compliance with pharmacological recommendations and average satisfaction with treatment. Anemia, drugs side effects, and SATMED-Q total score were significant predictors of the overall ARMS score in the univariate analysis, whereas the male gender and satisfaction with treatment improves this results. In multivariate analysis, significant predictors of lower adherence included family history of IHD, anemia and drugs side effects, while higher education and SATMED-Q overall score increased adherence. Treatment satisfaction is a significant predictor of increased overall treatment adherence as well as adherence in terms of drug intake and drug and prescription refills. Raising patient awareness should be an important goal of future educational activities. Int J Occup Med Environ Health. 2023;36(4):465-76.

Analysis of Physician Compliance with Guideline-Directed Medical Therapy for Patients with Heart Failure with Reduced Ejection Fraction: A Real-World Study.

Although compliance with the guideline recommendations for heart failure (HF) is associated with improved survival, the effects of medication on clinical practice often fail to meet expectations due to physician and/or patient-related reasons that are unclear. This study analyzed physicians' compliance with guideline-directed medical therapy (GDMT) based on real-world clinical data and identified risk factors of low compliance. This study included patients with HF, who were treated at the Affiliated Hospital of North Sichuan Medical College from July 2017 to June 2021. All patients were divided into high compliance, moderate compliance, and low compliance with GDMT groups. The proportion of patients receiving treatment in compliance with GDMT was analyzed, the relationship between compliance with GDMT and clinical outcomes was evaluated, and the risk factors of low compliance were identified. Of all patients with HF included in the study, 498 (23.8%) had low compliance with GDMT, 1413 (67.4%) had moderate compliance with GDMT, and 185 (8.8%) had high compliance with GDMT. The readmission rate of patients in the moderate compliance with GDMT group was significantly higher than that in the high and low compliance groups (p = 0.028). There were no significant differences in the rates of severe cardiovascular disease among the three groups. The mortality rate of patients in the high compliance with GDMT group was significantly higher than that of the other groups (p 0.001). We found that a history of hypertension; New York Heart Association (NYHA) classification (III and IV vs. I); and abnormal heart rate, high-sensitive troponin T (hsTnT), N-terminal prohormone of brain natriuretic peptide (NT-proBNP), uric acid, and left ventricular diastolic dysfunction (LVDD) were all significantly associated with low compliance with GDMT. The proportion of physicians' compliance with GDMT in treating patients with HF is low. Risk factors of low compliance include hypertension; NYHA classification (III and IV vs. I); and abnormal heart rate, hsTnT, NT proBNP, uric acid, and LVDD.