A quick and accurate estimate of the seismic demand of tall buildings is one of the important issues in the seismic evaluation of buildings. Nonlinear response time history analysis method (NLRHA) is considered as the most accurate and rigorous method, but the computation requirement of NLRHA for tall buildings can be complex and very time-consuming. Whereas the conventional pushover procedure is not capable of reasonably estimating seismic demand of mid and high rise-buildings, due to the oversimplification of conventional pushover approaches and the complexity of seismic performance of buildings. In this paper, a quick, yet effective, method of analysis, named as a spectrum-based pushover analysis (SPA) method, is proposed to estimate the seismic demand of tall buildings. In the SPA procedure, the very complex and complicated dynamic coupling effect of modes of the nonlinear seismic performance of a building is simplified, and the consecutive pushover technique is adopted to consider the simplified coupling effect. Comparison of the results obtained from NLRHA, the modal pushover analysis method, the consecutive modal pushover analysis method and the proposed SPA method is made. It is seen that the SPA method predicted the seismic demand of buildings well, including the inter-storey drift ratio and hinge plastic rotation, which are very close to those of NLRHA. Owing to its accuracy, effectiveness, and spectrum-based calculation procedure, the proposed SPA procedure is considered to be a very promising tool for predicting the seismic demand of tall buildings.