This paper, based on the reality of China, carried out empirical analysis to labor trans-regional flow status and influence on the regional economic growth. The thesis made an empirical conclusion from the following five aspects: selection of enterprise location and industrial agglomeration, regional growth effect of labor Mobility, impact on regional disparities of Labor Mobility, Labor Mobility's employment effect, and the recycling of income and price pas s-through effect of Labor Mobility. And then makes predictions about development tendency of Labor Mobility in china and puts forward some countermeasures and suggestions about development strategy of promote our country's Labor Mobility.