BackgroundSchizophrenia is a group of chronic diseases with unknown causes. It usually starts slowly or subacute in young adults. In clinical practice, it is often manifested as a syndrome with different symptoms, involving various obstacles in perception, thinking, emotion, and behavior, as well as uncoordinated mental activities. Patients are generally conscious and their intelligence is basically normal, but some patients may suffer from cognitive impairment during the disease process. Schizophrenia has a huge impact on the mental health of vocational college students. The study will strengthen education and management and combine psychotropic drugs to conduct clinical treatment of vocational college students’ schizophrenia and observe its effect, so as to provide a scientific basis for the clinical treatment of vocational college students’ schizophrenia.Subjects and Methods60 students suffering from schizophrenia were selected from several vocational schools and divided into two groups: drug treatment group and combined treatment group. The students in the drug treatment group take conventional psychotic drugs for treatment, while the students in the combined treatment group take conventional psychotic drugs for treatment and also receive strengthened education and management. Before and after treatment, Minnesota Multiphasic Personality Inventory (MMPI) was used to evaluate the condition of schizophrenia of the two groups of students, and the evaluation results were statistically analyzed.ResultsThe MMPI scores of the two groups of students before treatment were 65.32±3.24 and 65.48±3.21 respectively. The MMPI scores of the two groups of students after treatment decreased compared with those before treatment. The average MMPI score of the drug treatment group after treatment was 57.46±3.18, and the average MMPI score of the combined treatment group was 45.83±2.87, which was statistically significant (P < 0.05) compared with the scores before the experiment. However, the remission effect of the combined treatment group after treatment was more significant than that of the drug treatment group. Table 1 shows the comparison of MMPI scores between the two groups before and after the experiment.Table 1.Comparison of MMPI scores of patients before and after the experimentGroupBefore treatmentAfter treatmentPMedication group65.32±3.2457.46±3.18>0.05Combined treatment group65.48±3.2145.83±2.87<0.05P>0.05>0.05-ConclusionsConventional psychotic drug treatment has a certain effect on the remission of schizophrenia in vocational college students, but the treatment plan of strengthening education management and combining psychotic drugs proposed in the study has a more significant effect on the remission of schizophrenia in vocational college students, providing a scientific basis for the clinical treatment of schizophrenia of vocational college students.