Purpose. Justification of principles and methodology for effective calculation of the equipment costs and optimization of transport means maintenance. Methodology. The results of the presented scientific research were obtained using general and special methods of cognition: abstract and logical analysis, systematization and combination, method of theoretical generalization, method of dialectical cognition, deduction and induction, and statistical analysis. This paper analyzes the relationship between the probability of failure prevention by the maintenance system and the associated costs. The research investigates how the variation in the technical condition change rate influences the length of the operation cycle and the rate of its decline. The study’s outcomes are analyzed, including the formation of points of minimum unit costs, the effect of spare parts’ cost, and the practical importance of the conclusions drawn. Findings. This paper outlines the economic methodology for determining the specific expenses of maintaining means of transport. The methodology considers the distribution of expenses for spare parts, labor, and other components. Using this methodology, it is possible to estimate the total costs of maintenance and make informed decisions about the efficient use of resources. It has been determined that the cost of spare parts impacts the efficiency of the maintenance system. Therefore, it is imperative to balance the cost for spare parts and safety, while considering the probability of failure. The method outlined in this work is versatile, which allows its adaptation and application to the specialized road transport. Originality. The paper further develops the methodological approach to calculating equipment costs for transport maintenance, which is used to improve service efficiency and reduce expenses. The approach enables a comprehensive evaluation of the outcomes of enhancing failure prevention probability through the maintenance system. It also aids in managing unused parts’ resources, particularly during short operating cycles. Practical value. The study’s findings can optimize the maintenance system, increase operational efficiency, and enhance the safety and reliability of means of transport, while reducing the costs associated with spare parts, labor, and other maintenance components. This approach aids in conserving resources, reducing operating costs, and is crucial for the financial stability and profitability of management companies.