Motivated by the classical problem of privacy amplification, Dodis and Wichs [in Proceedings of the 41st Annual ACM Symposium on Theory of Computing, 2009, pp. 601--610] introduced the notion of a nonmalleable extractor, significantly strengthening the notion of a strong extractor. A nonmalleable extractor is a function $\mathsf{nmExt}:\{0,1\}^n\times\{0,1\}^d\to\{0,1\}^m$ that takes two inputs---a weak source $W$ and a uniform (independent) seed $S$---and outputs a string $\mathsf{nmExt}(W,S)$ that is nearly uniform given the seed $S$ as well as the value $\mathsf{nmExt}(W,S')$ for any seed $S'\neq S$ that may be determined as an arbitrary function of $S$. The first explicit construction of a nonmalleable extractor was recently provided by Dodis et al. [Privacy Amplification and Non-malleable Extractors via Character Sums, preprint, arXiv:1102.5415 [cs.CR], 2011]. Their extractor works for any weak source with min-entropy rate $1/2+\delta$, where $\delta>0$ is an arbitrary constant and outputs up to a linear number of bits but suffers from two drawbacks. First, the length of its seed is linear in the length of the weak source (which leads to privacy amplification protocols with high communication complexity). Second, the construction is conditional: when outputting more than a logarithmic number of bits (as required for privacy amplification protocols), its efficiency relies on a longstanding conjecture on the distribution of prime numbers. In this paper we present an unconditional construction of a nonmalleable extractor with short seeds. For any integers $n$ and $d$ such that $2.01\cdot\log n\leq d\leq n$, we present an explicit construction of a nonmalleable extractor $\mathsf{nmExt}\colon\{0,1\}^n\times\{0,1\}^d\to\{0,1\}^m$, with $m=\Omega(d)$ and error exponentially small in $m$. The extractor works for any weak source with min-entropy rate $1/2+\delta$, where $\delta>0$ is an arbitrary constant. Moreover, our extractor in fact satisfies an even more general notion of nonmalleability: its output $\mathsf{nmExt}(W,S)$ is nearly uniform given the seed $S$ as well as the values $\mathsf{nmExt}(W,S_1),\dots,\mathsf{nmExt}(W,S_t)$ for several seeds $S_1,\dots,S_t$ that may be determined as an arbitrary function of $S$, as long as $S\notin\{S_1,\dots,S_t\}$. By instantiating the framework of Dodis and Wichs with our nonmalleable extractor, we obtain the first 2-round privacy amplification protocol for min-entropy rate $1/2+\delta$ with asymptotically optimal entropy loss and polylogarithmic communication complexity. This improves the previously known 2-round privacy amplification protocols: the protocol of Dodis and Wichs, whose entropy loss is not asymptotically optimal, and the protocol of Dodis et al., whose communication complexity is linear.