Middle East Research Articles

Abortion as an ethical-religious problem in Islam

The relevance of this article lies in the increasingly active public discussion among Muslims, the challenge posed by the induced termination of pregnancy by Muslims and the problems stemming from it. The increasing calls from Muslims to the spiritual authorities for clarification of this issue in various countries confirm this trend. However, a comprehensive understanding of Islamic attitudes towards induced abortion remains poorly understood. Islamic discourse permeates the entire socio- cultural facet of Muslim society. It is transforming and developing among the communities of modern Muslim countries, matching the dynamics of changes in attitudes on the issue of induced termination of pregnancy from the early Middle Ages to the beginning of the ХХI century inclusive. In this regard, the purpose of this work is to describe and reveal the question about the use of abortion in the Islamic world. In the study specific “introductory” examples from the Muslim world are presented for disclosure given by those. In the course of this study, the topic of abortion as a social and medical phenomenon was briefly studied and covered through the lens of terminology, social, medical, religious and legislative factors. The process of transforming Islamic religious ethics with regard to abortion is briefly outlined. In the sequence since the beginning of Islam and the development of this religious speech in the ХХI century, the prism of the views of the Sunni and Shiitic directions, as well as the 4 Sunni theological schools, in the context of solving the problem of abortion. Examples were provided of legislative solutions to the problem of induced termination of pregnancy in some Muslim countries, Asia Minor, the Middle East, North Africa and Australia. The materials of this article contribute to the study of ethical and religious problems in Islam.

Examining contributing factors for the implementation of inclusion students with disabilities from the perspective of university academics in Saudi Arabia

Inclusive education focuses on implementing education for individuals who do not follow typical learning trajectory and require special educational needs (SEN). Educational systems in many countries around the world, including Saudi Arabia, tend to implement and practise inclusive education in order to fulfill relevant international conventions and achieve educational standards of acceptable quality in educating children and young people with medical and neurodevelopmental conditions. This study seeks to reveal some of the factors that may help to overcome the obstacles faced in the implementation of inclusive education from the point of view of academics of special education in Saudi universities. To achieve this goal, the study used semi-structured interviews as its primary tool for data collection. Sixteen male and female faculty members specialized in special education in several Saudi public universities were interviewed. The data were analysed thematically. Two master themes were derived from the thematic analyses, 1) theoretical factors and 2) applied factors. Both master themes had several sub-themes. A number of factors were identified as helping to implement inclusive education thereby changing the behaviours and attitudes towards including students with disabilities Saudi context. It is suggested here that similar factors might exist in other countries in Middle East and beyond.

:Imagined Geographies in the Mediterranean, Middle East, and Beyond

:<i>Imagined Geographies in the Mediterranean, Middle East, and Beyond</i>

Spinach genomes reveal migration history and candidate genes for important crop traits.

Spinach (Spinacia oleracea) is an important leafy crop possessing notable economic value and health benefits. Current genomic resources include reference genomes and genome-wide association studies. However, the worldwide genetic relationships and the migration history of the crop remained uncertain, and genome-wide association studies have produced extensive gene lists related to agronomic traits. Here, we re-analysed the sequenced genomes of 305 cultivated and wild spinach accessions to unveil the phylogeny and history of cultivated spinach and to explore genetic variation in relation to phenotypes. In contrast to previous studies, we employed machine learning methods (based on Extreme Gradient Boosting, XGBoost) to detect variants that are collectively associated with agronomic traits. Variant-based cluster analyses revealed three primary spinach groups in the Middle East, Asiaand Europe/US. Combining admixture analysis and allele-sharing statistics, migration routes of spinach from the Middle East to Europe and Asia are presented. Using XGBoost machine learning models we predict genomic variants influencing bolting time, flowering time, petiole color, and leaf surface texture and propose candidate genes for each trait. This study enhances our understanding of the history and phylogeny of domesticated spinach and provides valuable information on candidate genes for future genetic improvement of the crop.

Traditional Chinese Medicine as the preventive and therapeutic remedy for COVID-19.

The coronavirus disease 2019 (COVID-19) pandemic still has tremendous impacts on the global socio-economy and quality of living. The traditional Chinese Medicines (TCM) approach showed encouraging results during previous outbreaks of Severe Acute Respiratory Syndrome-related coronavirus (SARS-CoV) and the Middle East Respiratory Syndrome Coronavirus (MERS-CoV). With limited treatment availability, TCM herbs and formulations could be viable to reduce COVID-19 symptoms and potential sources for discovering novel therapeutic targets. We reviewed 12 TCM herbs and formulations recommended for COVID-19 management by the National Health Commission and National Administration of Traditional Chinese Medicine, the People's Republic of China. This article explored the Chinese national authorities' guidelines from 2003 to 2020, the scientific data in public databases for the recommended TCM remedies, and their potential mechanistic actions in COVID-19 management. Several TCM herbs and formulations could potentially benefit COVID-19 management. The recommended TCM oral preparations list are Huoxiang zhengqi, Jinhua Qinggan, Lianhua Qingwen, and Shufeng jiedu; the recommended injection preparations comprise Xiyanping Xuebijing, Re-Du-Ning, Tanreqing, Xingnaojing, Shenfu, Shengmai, and Shenmai. TCM remedies are viable options for symptom alleviation and management of COVID-19. The current SARS-CoV-2 pandemic presents an opportunity to find novel therapeutic targets from TCM-active ingredients. Despite the recommendations in Chinese National guidelines, these remedies warrant further assessments in well-designed clinical trials for their efficacies in COVID-19.

GEOGRAPHICAL DESCRIPTION AND PHARMACOLOGICAL PROPERTIES OF DICHANTHIUM ANNULATUM: A REVIEW

Dichanthium annulatum herb belongs to Poaceae family; also referred to as marvel grass. It grows to a height of about 25cm. Due to its straightforward and affordable development from seed, it is used as forage. The present review was based on the geographical description and pharmacological properties of dichanthium annulatum. It is indigenous to regions of Africa, the Middle East, and tropical Asia. It has been brought to many different regions of the world for cultivation, and in some, like Australia, it has established itself as a native species. This pasture grass is well-liked in various regions. It can be harvested for hay and silage and used in fields to graze livestock. It can grow in a wide range of soil types, including those with a lot of clay and sand, poor drainage, and a little saline and alkaline soil. It creates turf that can withstand pressure from grazing animals. It can bounce back from fire and drought, but it can't stand frost and shade as well. Although it doesn't need fertiliser, it does benefit from a little more nitrogen. It concluded that D. annulatum is versatile herb having diverse pharmacological activities including antioxidant, antioxidant activity index, DNA damage protection assay, antimicrobial assay, and cytotoxic activity. It also reported for protective effect against DNA damage. These biological properties are reported due to numerous phytochemicals present in the D. annulatum herb.

Nutritional Beliefs and Practices of Arabic-Speaking Middle Eastern Mothers Living in the United States.

Culture and acculturation influence nutritional beliefs. Little is known about the Arabic population in the United States. In this study, Arabic-speaking Middle Eastern mothers' perceptions of motherhood and childhood nutritional beliefs and practices are explored. Semi-structured interviews with 12 mothers from Arabic-speaking Middle Eastern countries. Food and family are central to everyday life. Mothers worked hard to maintain traditional nutritional practices with their school-age children. Findings can enhance school nurses' ability to collaborate with mothers in nutritional education and address any issues in the classroom.

Carbon based sensors for air quality monitoring networks; middle east perspective

IoT-based Sensors networks play a pivotal role in improving air quality monitoring in the Middle East. They provide real-time data, enabling precise tracking of pollution trends, informed decision-making, and increased public awareness. Air quality and dust pollution in the Middle East region may leads to various health issues, particularly among vulnerable populations. IoT-based Sensors networks help mitigate health risks by offering timely and accurate air quality data. Air pollution affects not only human health but also the region’s ecosystems and contributes to climate change. The economic implications of deteriorated air quality include healthcare costs and decreased productivity, underscore the need for effective monitoring and mitigation. IoT-based data can guide policymakers to align with Sustainable Development Goals (SDGs) related to health, clean water, and climate action. The conventional monitor based standard air quality instruments provide limited spatial coverage so there is strong need to continue research integrated with low-cost sensor technologies to make air quality monitoring more accessible, even in resource-constrained regions. IoT-based Sensors networks monitoring helps in understanding these environmental impacts. Among these IoT-based Sensors networks, sensors are of vital importance. With the evolution of sensors technologies, different types of sensors materials are available. Among this carbon based sensors are widely used for air quality monitoring. Carbon nanomaterial-based sensors (CNS) and carbon nanotubes (CNTs) as adsorbents exhibit unique capabilities in the measurement of air pollutants. These sensors are used to detect gaseous pollutants that includes oxides of nitrogen and Sulphur, and ozone, and volatile organic compounds (VOCs). This study provides comprehensive review of integration of carbon nanomaterials based sensors in IoT based network for better air quality monitoring and exploring the potential of machine learning and artificial intelligence for advanced data analysis, pollution source identification, integration of satellite and ground-based networks and future forecasting to design effective mitigation strategies. By prioritizing these recommendations, the Middle East and other regions, can further leverage IoT-based systems to improve air quality monitoring, safeguard public health, protect the environment, and contribute to sustainable development in the region.

Developing an integrated framework for Marine Cultural Heritage (MCH) and Marine Protected Areas (MPA) across Africa and the Middle East

There is currently a significant imbalance in existing marine resource management frameworks. Across Africa and the Middle East there is a developing network of marine protected areas focused on natural heritage but with very limited engagement with area-based management for cultural heritage. Yet both natural and cultural heritage resources are subject to the same considerable threat levels from both natural and anthropogenic processes of change. The MarEA project is engaged in an extensive programme of mapping and documentation of endangered cultural heritage sites and landscapes across the MENA region. During the course of this and aligned work, its engagement with coastal communities and international practice has identified a clear need for more informed and holistic approaches to marine resource management. This study presents a model for the integrated management of natural and cultural heritage and proposes a framework for the future identification and designation of Marine Cultural Heritage in Protected Areas.

Well‐to‐wheels analysis of greenhouse gas emissions for passenger vehicles in Middle East and North Africa

AbstractBattery electric vehicles (BEVs) are widely considered a pathway to achieve low carbon mobility. BEVs emit zero emissions from the tailpipe, but their life cycle carbon reduction compared to gasoline vehicles varies based on primary energy sources, electricity generation, and use efficiency. The Middle East and North Africa (MENA) region is an area rich in fossil fuels, meriting a detailed comparison between the emissions from BEV and other powertrains. We developed a MENA‐specific life cycle model that estimates well‐to‐wheel (WTW) greenhouse gas (GHG) emissions from passenger transport with internal combustion engine vehicles (ICEVs), hybrid electric vehicles (HEVs), plug‐in hybrid electric vehicles, and BEVs. MENA's average WTW GHG emissions for all supply chain steps including combustion emissions from vehicle operation are 767 g/kWh and 84 g CO2eq/MJ for electricity and gasoline, respectively, but are highly variable due to heterogeneity in upstream supply chains. The use of hybrid gasoline ICEVs provides the largest emission reduction opportunity for existing vehicle fleets in 9 of the 16 MENA countries. For these nine countries, replacing gasoline ICEVs with HEVs could, on average, reduce country‐level life cycle GHG emissions by 47%. There is a similar emission reduction opportunity for 14 of the 16 MENA countries when normalizing vehicle efficiencies irrespective of the powertrain shares and other trends in existing vehicle fleets. Future scenario analysis shows that BEVs would have the lowest WTW GHG emissions among all powertrains in most MENA countries only if significantly reduced electricity transmission losses and cleaner grid mix are realized, although a high cost of infrastructure developments is expected.

A perplexing case report of concomitant multiple sclerosis and myasthenia gravis

Introduction &amp; Importance: The co-occurrence of multiple sclerosis (MS) and myasthenia gravis (MG) within the Middle East and North African Region (MENA) has been scarcely reported in current literature. This rare case report explores the pathophysiological mechanisms and potential avenues of treatment modalities. Such insights can potentially facilitate the development of more efficacious and targeted treatment modalities and perhaps pave the way for disease prevention. Case Description: 29-year-old female patient presented with diplopia of two weeks duration associated with occasional blurred vision in the left eye. On physical examination, she was discovered to have marked left eye ptosis. A visual evoked potential (VEP) test was performed, which revealed asymmetrical delay. MRI imaging revealed a few white matter hyperintense foci noted at both periventricular regions and the corpus callosum with the characteristic appearance of Dawson’s fingers and thus MS was diagnosed. An anti-acetylcholine receptor antibody test returned positive, confirming the diagnosis of concurrent MG. Clinical Discussion: Proposed pathophysiological mechanisms underlying the concurrent manifestation of both diseases include, among others, the involvement of HLA haplotype and non-HLA genotypes, as well as the immunogenetic influence of specific transcription factors. Notable HLA haplotype genes include DRB1 and HLA-DQ5 genes. In contrast, non-HLA genes include the interleukin-4 receptor (IL4RA) and factor forkhead box P3 (FOXP3). Conclusion: Considering the similar immunological background of the two diseases, ideally, a single therapeutic modality could be used for management. This will hopefully simplify the patient’s treatment regimen and may ultimately reduce the treatment cost and patient burden.

The Development of Video Game Representations of the Middle East

This article critically explores the historical representation of the Middle East in video games until 2002 and following the 9/11 event. Using thematic analysis, we identify four main themes and discuss how this representation shifts with time, offering a brief overview of the broader context. I argue that there is a clear association between political developments and this western representation, for we can clearly observe changes from the romantic, exotic, and orientalist views of the region and Arab and Muslim figure shown within the realms of the Arabian Nights theme to a more militant figure and dangerous place due to featuring armed conflict in the Middle East such as the first Gulf War. Though not included in the discussion, 9/11 introduced a more negative and Islamophobic representation that is associated with Islamist terrorism, and it marks the latest development in these themes.

A deep catalogue of protein-coding variation in 983,578 individuals.

Rare coding variants that significantly impact function provide insights into the biology of a gene1-3. However, ascertaining their frequency requires large sample sizes4-8. Here, we present a catalogue of human protein-coding variation, derived from exome sequencing of 983,578 individuals across diverse populations. 23% of the Regeneron Genetics Center Million Exome data (RGC-ME) comes from non-European individuals of African, East Asian, Indigenous American, Middle Eastern, and South Asian ancestry. This catalogue includes over 10.4 million missense and 1.1 million predicted loss-of-function (pLOF) variants. We identify individuals with rare biallelic pLOF variants in 4,848 genes, 1,751 of which have not been previously reported. From precise quantitative estimates of selection against heterozygous loss-of-function, we identify 3,988 loss-of-function intolerant genes, including 86 that were previously assessed as tolerant and 1,153 lacking established disease annotation. We also define regions of missense depletion at high resolution. Notably, 1,482 genes have regions depleted of missense variants despite being tolerant to pLOF variants. Finally, we estimate that 3% of individuals have a clinically actionable genetic variant, and that 11,773 variants reported in ClinVar with unknown significance are likely to be deleterious cryptic splice sites. To facilitate variant interpretation and genetics-informed precision medicine, we make this important resource of coding variation from the RGC-ME accessible via a public variant allele frequency browser.

Awareness, knowledge, and behaviors regarding trans unsaturated fatty acids in a sample of Lebanese adults

AbstractLebanon is a country in the Middle East that had been witnessing nutrition transition to a westernized diet high in trans fats (TFs) and saturated fatty acids (TFAs) that had been linked to cardiovascular diseases and many other health issues. This study examines TF‐related awareness, knowledge, and self‐reported behaviors among a sample of Lebanese adults aged between 18 and 64 years, as well as their association with sociodemographic factors and anthropometric measurements. Using a multicomponent questionnaire, a cross‐sectional study was conducted online, across all Lebanese regions based on a convenience sampling method (n = 401). Factors associated with TF‐related awareness, knowledge, and behaviors were examined by multivariate linear regression analysis. The study highlighted specific gaps in TF‐related awareness, knowledge, and behavioral practices as well as differences by sociodemographic factors. Most of the participants (36%) had heard of partly hydrogenated oils (PHOs) rather than TFs (49%). A higher proportion of respondents (54%) said they understood a little about TFs, the majority had inadequate knowledge about the foods that contain TFs, and 44% said they would not give up eating their favorite snack even if they knew it contains TFs. Overall, consumers' awareness and knowledge about TFs are rather low and the majority had fair behavioral practices. In addition, being a woman and having higher education level were significantly associated with higher levels of TFs awareness, knowledge, and behavior scores. Higher behavior scores were shown in older participants, married, and those who had part‐time jobs, whereas having higher income and normal weight were significantly associated with higher awareness scores. These findings offer valuable insight into TF‐related awareness, knowledge, and behaviors in a sample of Lebanese adults and provide key information that could spur the development of evidence‐based TFs reduction interventions specific to the Middle East.

Immediate effects of Ramadan on objective time asleep in male youth football players from the Middle East: an interrupted time-series study

ABSTRACT Objective To examine the abrupt effects of Ramadan onset on actigraphy-based time asleep in male youth Muslim football players. Methods We adopted a quasi-experimental, interrupted time-series research design and tracked objective time asleep over a minimum of 12 consecutive nights in the two weeks prior to and immediately after Ramadan onset, respectively. Twenty-two, male academy student-athletes (chronological age range: 12.6 to 16.2 years) participated in the study (464 individual observations). Segmented generalized mixed-effects modelling estimated the effects of Ramadan onset on time asleep during the first period of night sleep only. Results Ramadan onset led to an immediate mean reduction of 89 min (95% confidence interval [CI], 54 to 123 min) in time asleep during the first period of night sleep compared to pre-Ramadan sleep patterns. Model-adjusted estimated marginal means for time asleep were ~ 5.7 h (95%CI, 5.1 to 6.2 h) before and ~ 4.2 h (95%CI, 3.6 to 4.7 h) after Ramadan onset. Night sleep interruptions resulting in two or more fragmented periods accounted for 8% (95%CI, 2 to 21%) to 19% (95%, 11 to 29%) of sleep observations before and after Ramadan onset, respectively. Conclusions The onset of Ramadan determined an abrupt reduction in time asleep of ~ 1 h 30 min in the first period of a night cycle and contributed to additional problems of heterogeneous sleep fragmentation that can impact optimal school learning and youth athlete performance development processes.

Building Information Modeling Capability in Mitigating Change Orders and Cost Overrun

The Jordanian construction industry faces notable challenges, particularly about variation orders (VOs), contributing to budget overruns and project delays. The Jordan Engineers Association poll in 2020 found that variation orders (VOs) accounted for 23% of cost overruns in construction projects in Jordan. Research undertaken by the Ministry of Public Works and Housing in 2019 found an average of 948 change orders per year, representing 25.5% of the total value of the projects. Our study introduces a highly tailored evaluation method to gauge the effectiveness of Building Information Modelling (BIM) in addressing these challenges. The study assesses the efficacy of Building Information Modeling (BIM) in diminishing variation orders (VOs) by examining sophisticated BIM functionalities. The study employs an intricate case study and diverse construction project data to construct a model that assesses the capacity of BIM to reduce project modifications and enhance cost efficiency. A novel approach has been devised to enhance the optimization of building information modeling (BIM) in the construction industry of Amman, Jordan. The objective of the concept is to minimize variation orders (VOs) and enhance project management. The study employs research approaches, such as semi-structured interviews and questionnaires, to pinpoint the essential abilities contributing to change orders. After comprehensively analyzing BIM's global and Middle Eastern applications, we created the model. The findings indicate that enhancing Building Information Modeling (BIM) capabilities can effectively mitigate the occurrence of variation orders within Jordan's building sector. The approach promotes the cooperation of stakeholders, sets quantifiable benchmarks, and strategically employs BIM for preliminary risk assessment. This research substantially enhances the productivity and cost-effectiveness of construction projects in Jordan, offering vital insights for professionals and policymakers.

Cognitive skills and economic growth in the twenty-first century: Evidence from PISA and cognitive ability studies

In recent years, some educational researchers have questioned the theory of a robust relationship between test scores in international large-scale assessments such as PISA and lagged economic growth. However, both the proponents and opponents of such a human capital approach have mainly focused on earlier growth patterns during the twentieth century. Hence, the current article analysed the relationship between PISA 2000 and economic growth in 2010–2019 for 31 countries, and composite cognitive skills for 80 countries and their relationships with economic growth in 2010–2019. The results indicate that PISA scores or other cognitive skill measures could to some extent predict economic growth between 2010 and 2019, even when controlling for a significant number of variables. In a consecutive analysis, the relations were substantially associated with Middle Eastern countries because many countries from this region experienced political instability and decreasing oil revenues throughout this period. Hence, it is possible that regional and contextual relationships affect these patterns.

Global epidemiology and antimicrobial resistance of Enterobacterales harbouring genes encoding OXA-48-like carbapenemases: insights from the results of the Antimicrobial Testing Leadership and Surveillance (ATLAS) programme 2018-2021.

The recent emergence of carbapenem-resistant Enterobacterales poses a major and escalating threat to global public health. This study aimed to analyse the global distribution and antimicrobial resistance of Enterobacterales harbouring variant OXA-48-like carbapenemase-related genes. Enterobacterales isolates were collected from the Antimicrobial Testing Leadership and Surveillance (ATLAS) programme during 2018-2021. Comprehensive antimicrobial susceptibility testing and β-lactamase gene detection were also conducted, along with statistical analysis of the collected data. Among the 72 244 isolates, 1934 Enterobacterales isolates were identified to harbour blaOXA-48-like genes, predominantly Klebsiella spp. (86.9%). High rates of multidrug resistance were observed, with only ceftazidime/avibactam and tigecycline showing favourable susceptibility. A discrepancy between the genotype and phenotype of carbapenem resistance was evident: 16.8% (233 out of 1384) of the Enterobacterales isolates with blaOXA-48-like genes exhibited susceptibility to meropenem. Specifically, 37.4% (64/95) of Escherichia coli strains with blaOXA-48-like genes displayed meropenem susceptibility, while the corresponding percentages for Klebsiella pneumoniae and Enterobacter cloacae complex were 25.2% (160/1184) and 0% (0/36), respectively (P < 0.05). Geographical analysis revealed that the highest prevalence of blaOXA-48-like genes occurred in Asia, the Middle East and Eastern Europe. The proportion of K. pneumoniae isolates harbouring blaOXA-232 increased from 23.9% in 2018 to 56.0% in 2021. By contrast, the proportion of blaOXA-48 decreased among K. pneumoniae isolates during 2018-2021. This study underscores the widespread and increasing prevalence of blaOXA-48-like genes in Enterobacterales and emphasizes the need for enhanced surveillance, improved diagnostic methods and tailored antibiotic stewardship to combat the spread of these resistant pathogens.

The impact of the COVID-19 pandemic on the financial performance and stability of Islamic banks

Purpose The purpose of this paper is to investigate the impact of the COVID-19 pandemic on the financial performance and stability of Islamic banks (IBs) in the Middle East, North Africa and Southeast Asia (MENASA) region. Design/methodology/approach The sample consists of 50 IBs across 13 MENASA countries. The data covers 11 quarters, starting in Q1 2019 and ending in Q3 2021, and are collected from banks’ quarterly reports. The authors proxy financial performance by three measures, namely, return on assets (ROA), return on equity (ROE) and cost-to-income (Cost/Income). For financial stability, the authors use two indicators: insolvency risk (log Z-score) and asset risk (ROA/SDROA). The methodology is based on the generalized least squares method estimation. Findings The results showed a significant and negative impact of COVID-19 on two performance measures of IBs (ROA and ROE) suggesting that IBs were significantly affected during the earlier pandemic. As well, the authors found strong evidence of the impact of COVID-19 on the insolvency risk and asset risk of the studied banks. Practical implications The study of COVID-19’s impact on the performance and stability of IBs in MENASA countries permits the banks’ regulators and policymakers to ameliorate the banks’ financial performance and reinforce their supervisory actions. Also, it gives them assistance to guarantee the financial stability of these banks in times of crisis. Originality/value This study provides significant financial information and policy implications for stakeholders involved in the banking sector in MENASA countries. Consequently, IBs must guarantee their profits and stability to ensure their competitiveness versus conventional banks during the period of crisis.

The research on high efficiency water injection development of carbonate rock reservoir in the middle east

More and more attention has been paid to the waterflood development of carbonate reservoir in the Middle East with continuous expansion of the scale of carbonate reservoir development. Strong non-homogeneity of carbonate reservoirs results in serious conflicts between injection and production, causing low degree of water-driven control in the well network, and low degree of vertical mobilization. This article takes the main reservoir of an oil field in the Middle East region as an example, combining geological evaluation, dynamic analysis, and reservoir development strategies to study the effectiveness of water injection development in carbonate reservoirs. It shows that there is a correlation between pore type, oil-water relative permeability, and development method in the development of carbonate reservoirs. For reservoirs with matrix pores and micropores, water injection should be strengthened in the later stage of development; for reservoirs with dissolved pores and coarse pores, the iso-permeability point is relatively high, and the later development should focus on balanced water injection. Three different waterflooding models for formation development are designed to verify the feasibility of fine waterflooding schemes. The main differences are that one set of well patterns is combined injection and production, and three sets of well patterns are layered system waterflooding. The results show that the development effect in layered system waterflooding is the best. The daily production can be increased by about 16%, the cumulative oil production can be increased by about 8%, and the recovery factor can be increased by about 3%. Eventually, the stable oil and water control of carbonate reservoir can be realized.