Middle-aged Elderly Group Research Articles

Endoscopic and clinicopathological features of young, middle-aged, and elderly patients with advanced gastric cancer in Fuzhou area

Objective To investigate the endoscopic and clinicopathological features between the young, middle-aged, and elderly patients with advanced gastric cancer in Fuzhou area. Methods The clinical data of 2 357 patients with advanced gastric cancer in digestive endoscopy center of Fujian Provincial Hospital from January 2010 to December 2015 were collected. All cases were divided into two groups, the youth group with age ≤ 40 years old, and the middle-aged and elderly group with age > 40 years old. The gender, pathological type, cancer position and endoscopic typing of patients were compared between the two groups by using chi-square test. Results In the whole 2 357 patients, the male to female ratio was 2.71∶1. The youth group had 120 cases (5.09%), the male to female ratio was 1∶1.07. The middle-aged elderly group had 2 237 cases (94.91%), the male to female ratio was 2.90∶1. The incidence of middle part gastric cancer in youth group was significantly higher than that in middle-aged and elderly group [43.33% (52/120) vs. 25.75% (576/2 237), χ 2 = 18.018, P = 0.000], however the incidence of upper part gastric cancer in middle-aged and elderly group was significantly higher than that in youth group [27.58% (617/2 237) vs. 6.67% (8/120), χ 2 = 25.568, P = 0.000]. Borrmann Ⅲ type were common in the two groups, but the proportion of Borrmann Ⅰ type in middle-aged and elderly group was significantly higher than that in youth group [20.79% (465/2 237) vs. 11.67% (14/120), χ 2 = 5.850, P = 0.016], the proportion of Borrmann Ⅳ type in youth group was significantly higher than that in middle-aged and elderly group [23.33% (28/120) vs. 11.27% (252/2 237), χ2 = 15.845, P = 0.000]. As compared with the middle-aged and elderly patients, youth patients had worse differentiation and growth type (P 0.05). In the middle-aged and elderly group, the incidence of upper part gastric cancer in male group was higher than that in female group [29.03% (483/1 664) vs. 23.39% (134/573), χ 2 = 6.790, P = 0.009], the incidence of middle part gastric cancer in female group was higher than that in male group [31.06% (178/573) vs. 23.92% (398/1 664), χ2 = 9.415, P = 0.002]. In the middle-aged and elderly group, the female patients had worse differentiation than the males (P < 0.01). Conclusions There are differences in the endoscopic and clinicopathological features between young, middle-aged, and elderly patients with advanced gastric cancer in Fuzhou area. In young patients, the proportion of patients with middle part gastric cancer is high, while in middle-aged and elderly patients, the proportion of upper part gastric cancer is high. Compared with the middle-aged and elderly patients, the young patients have worse differentiation. Key words: Gastric neoplasms; Pathology; Endoscopes; Youth; Middle aged; Aged

A Comparision of the Effect of Sugammadex on the Recovery Period and Postoperative Residual Block in Young Elderly and Middle-Aged Elderly Patients.

The importance of the characteristics of anesthesia and postoperative residual curarization (PORC) in the elderly population should be a growing concern in this century. To investigate the effect of sugammadex on the duration of the recovery from neuromuscular blocking agents and postoperative residual curarization in the young elderly and middle-aged elderly patients who underwent elective laparoscopic cholecystectomy, followed by a train of four (TOF) watch monitorization. Prospective clinical trial study. Sixty patients over the age of 65 with American Society of Anesthesiologists I-III were divided into two groups according to their age (65-74 years old and ≥75 years old). Patients received sugammadex (2.0 mg/kg iv) at the reappearance of the second twitch of the TOF as an agent for reversal of neuromuscular blockage at the end of surgery. Patients were extubated at the time of TOF ≥0.9. The patients' TOF responses were evaluated with regards to PORC in at the 5th minute and were followed up for one hour in the recovery room. Reintubation was applied for those patients who developed PORC and had peripheric oxygen saturation <90% despite being given 6 L oxygen per min with a face mask. The onset time of neuromuscular blocking agent and time from T2 to achieve TOF ratio 90% (the duration of sugammadex effect) or over were found to be longer in the middle-aged elderly group than in the young elderly group. A statistically significant relationship was found between age and the duration of TOF ratio to reach 0.9 in the same direction. The PORC incidence and rate of reintubation were found to be 1.7% in all patients. In our opinion, it is necessary to remember that the duration of sugammadex effect on the recovery period is prolonged for patients who are aged ≥75 years compared to patients aged between 65-74 years. (ClinicalTrials.gov Identifier: ACTRN12615000758505).

A Study on Women&amp;apos;s Health Status for Setting up Women&amp;apos;s Health Nursing Center and Developing Health Program

The purpose of this paper was to identify the performance of health promoting lifestyles and health perception over 18 years old women living Wonju city so that the results will be based for setting up women's health nursing center. The subjects were 1080 women selected by stratified and purposive sampling. The data were collected by self reporting questionnaire and interview from May to June, 1998. Data were analyzed by SPSS win program. The results were as follows : 1. The range of age was 18-84 years, The proportion according to women's lifecycle was premarital group 20.0%, delivery and rearing group 49.9%, over middle aged-elderly group 29.8%.2. The mean menarchial age was 15.2 and menopausal age was 48. Mean frequenices of pregnancy is 2.4 and artificical abortion rate is 36.4%. Primary cause of abortion was unwanted babies 42.8%. The practice rate of family planning was 79.4% and permanent sterilization rate was 37.6%.3. Fatigue was predominated problem in target population. Depression and headache was predominated in premarital group, headache and nervous felling in delivery and rearing group, arthritis and loss of memory in over middle aged-elderly group.4. Only 13.7% of the target population make some efforts for their health in compare to 85.9% have attention for their health. Perception of unhealthy rate was 9.1% in premarital group, 24.8% in delivery and rearing group, 30.1% in middle aged-elderly group.5. The average score of the HPLP(Health Promoting Lifestyle Profile) was 2.41. The variable with the highest degree of performance was interpersonal relationship, whereas the one with the lowest degree was the professional health maintenance. The significant difference was found in HPLP according to age, residential area, marital status, educational level, income level.6. Majority(95.1%) of the target population agreed on necessity for women's health nursing center. Proper location area was presented to women's center and public health center. The priority for health education program was proper diet, family health, stress management, and exercise.In conclusion, we should prepare the education program for women's health according to women's lifecycle, because health perception, HPLP, and education program needed was differentiated in women's lifecycle. Also we suggest that women's health nursing center based community was needed for proper management of women's health.