This study investigates the causes of soft-storey and weak-storey formations in low- and mid-rise RC (Reinforced Concrete) buildings in Türkiye. In the first phase of the study, 96 model buildings were designated for the examination of soft-storey irregularity when the ground floors are used for commercial purposes and the upper floors for residential use. The ground floor heights that would cause soft-storey irregularity in each of the selected buildings were determined according to the formulas given in the Türkiye Building Earthquake Code (TBEC) and the American Society of Civil Engineers Standard (ASCE). It was found that the ground floor heights obtained according to ASCE are usable in practice, whereas those obtained according to the TBEC, particularly for buildings over three storeys, are excessively high for practical use. This indicates that, even if the buildings in Türkiye are designed with very high ground floor heights, they do not have soft-storey irregularities, according to the TBEC, but soft-storey formation may occur in these buildings due to the high ground floor height as a result of the effects of earthquakes. Instead of the soft-storey irregularity coefficient limit value (nki > 2) found in the TBEC, this study proposes a new limit value to prevent the design of buildings with very high ground floors. In the second phase of the study, for the purpose of examining weak-storey irregularity, 105 model buildings differing in their infill wall layout, number of spans, span length, and number of storeys were selected. The weak-storey irregularity coefficients of each of these models were determined according to the TBEC. The results of the study revealed that buildings with no infill walls in one direction or with infill walls in only one of the exterior axes in one direction have a high risk of having weak storeys.