Mid 1990s Research Articles

A lesson for us all: the Hodgkin-Keynes long pore model of ion flux.

In this article we analyze the classic Hodgkin and Keynes 1955 paper describing investigations of the independence principle, with the expectation that there is much students and educators can learn from such exercises, most notably how the authors applied their diverse skill set to tackling the numerous obstacles that the study presented. The paper encompasses three of the physiology core concepts, cell membranes, flow down gradients, and scientific reasoning, which were recently assigned to the classes The Biological World, The Physical World, and Ways of Looking at the World, respectively. Thus, analysis of such a paper illuminates the relationships that exist between distinct concepts and encourages a holistic approach to understanding physiology. In-depth analysis of the paper allows us to follow the authors' thought processes from their realization that previous methods lacked the resolution to answer a fundamental question relating to ion movement across membranes to the application of a more sensitive technique and ultimately the development of a novel model describing ion flux. This paper was the culmination of work started in the mid-1930s, strongly supported the ionic theory of nervous conduction proposed by Hodgkin and Huxley, and predicted the presence of ion channels as narrow pores through which ions move sequentially four decades before these features were convincingly demonstrated.NEW & NOTEWORTHY We describe in detail Hodgkin and Keynes' investigation of the independence principle. It is our expectation that students and educators can benefit from following the thought processes applied by the authors as they navigated the complexities of experimental design and data analysis, culminating in development of a model whose elegant simplicity was convincing evidence of narrow membrane-bound pores, ion channels, that were the conduit for transmembrane ion movement.

Welfare ruination, debris and Europeans’ make-shift practices: A research agenda

The mainstream literature on welfare retrenchment, austerity and post-welfare states proposes that since the mid 1970s, welfare states are in a state of ‘permanent austerity’. To offer an alternative to such stories of loss and their problematic nostalgic retelling of recent European history, leaving out its imperial histories, this article proposes to look instead at welfare as the object of ruination. This approach builds on literatures that focus on the experience of austerity and institutional violence to take a step further towards everyday responsive practices. Building on the work of Ann Laura Stoler, studying ruination and debris opens up the possibility to look at (1) the long durée of the colonial heritage of welfare, (2) ruination as an active and violent process and (3) welfare debris and how European dwellers use it and live in it. For Europeans, living amidst ruins and in a time of ruination, then, the question is: how can they build a life with the welfare debris that they are left with? Who is able to navigate the ruins and who is not? For researchers, this perspective can inform a new research agenda: a redirection of attention from welfare as ‘organized provision’ to, instead, how people organize the provisional, improvising with the rubble that remains.

Fabrication of B-C-N nanosheets on Rh(111) from benzene – borazine mixtures

Atomic level studies of solid state surfaces performed in ultra-high vacuum (UHV) had already an energetic 15–20 years past when our research group in Szeged started working in this field in mid 1970s. Till then several very important methods had been developed, like UHV technology, commercially available electron and photoelectron spectroscopy techniques, etc. Characterization of metal and semiconductor (oxide) surfaces and their adsorption properties had already been widely studied. In any case, the last 40–50 years also witnessed great discoveries and exciting new techniques. Considering only the activity related to heterogeneous catalysis, the main focus of our research group, new breakthrough methods emerged like HREELS, RAIRS, SPM, NAPXPS, EXAFS, NEXAFS. Along this path, new experimental and theoretical approaches appeared like planar model catalysts and inverse catalysts, atomic level investigation and understanding of surface diffusion-controlled phenomena (particle growth and disruption, strong metal-support interaction (SMSI), decoration, spillover), atomic level identification of active sites, self-organized nano-systems, surface alloys and nanotemplates. It was great to participate in this magical activity for more than 50 years. Both internationally and locally in Szeged, in the last two decades, surface science has opened to the wide world of 2D materials like the semimetal graphene and the insulator hexagonal boron nitride. However, the formation of a mixed layer of C, B and N proved to be a difficult task due to the primary tendency for phase separation. In the present work, we report on a preparation method of honeycomb “BCN” materials on Rh(111) by using benzene/borazine mixtures as precursors. It was demonstrated that by a suitable choice of the growth parameters, the formation of large, separated graphene and h-BN islands can be avoided.

Bose Metals, from Prediction to Realization.

Bose metals are metals made of Cooper pairs, which form at very low temperatures in superconducting films and Josephson junction arrays as an intermediate phase between superconductivity and superinsulation. We predicted the existence of this 2D metallic phase of bosons in the mid 1990s, showing that they arise due to topological quantum effects. The observation of Bose metals in perfectly regular Josephson junction arrays fully confirms our prediction and rules out alternative models based on disorder. Here, we review the basic mechanism leading to Bose metals. The key points are that the relevant vortices in granular superconductors are core-less, mobile XY vortices which can tunnel through the system due to quantum phase slips, that there is no charge-phase commutation relation preventing such vortices from being simultaneously out of condensate with charges, and that out-of-condensate charges and vortices are subject to topological mutual statistics interactions, a quantum effect that dominates at low temperatures. These repulsive mutual statistics interactions are sufficient to increase the energy of the Cooper pairs and lift them out of condensate. The result is a topological ground state in which charge conduction along edges and vortex movement across them organize themselves so as to generate the observed metallic saturation at low temperatures. This state is known today as a bosonic topological insulator.

Mid-Level Personnel in the Finno-Ugric Republics of the RSFSR in the mid-1950s – mid 1970s: Proportion within the Total Number of Workers and Employees

Mid-Level Personnel in the Finno-Ugric Republics of the RSFSR in the mid-1950s – mid 1970s: Proportion within the Total Number of Workers and Employees

Men in European Union’s gender equality policies

Gender mainstreaming is designed to address the social roles of both women and men. How are men included in gender equality policies? I conduct an analysis of all gender equality strategies and annual reports of the European Commission – a global leader in this field – since 1982. I find that, since the mid 1990s, the Commission has included men as contributors to gender equality (‘problem solvers’). Yet, men’s disadvantages in education and health were only addressed between 2006 and 2015. Later on, men’s problems have been ignored, as they have been increasingly portrayed as a uniformly privileged group, undeserving of European policies. This withdrawal from addressing men’s problems exposes the tension between legitimising policies for one group (women) and addressing the needs of a complementary group (men). A novel approach to gender equality policies should revive the global debate on their meaning and implications. My findings also raise new questions about the power of the European Commission to construct policy target populations.

"Cultural Layer of Kurgan City": Determination, Studying, Findings, Issues and Prospects"

Cultural Layer of Kurgan City archaeological monument was established in 2005. Since 2009 it has been exposed to archaeological excavations at different city mansions dated 1700s – early 1900s and situated within the determined site of cultural heritage. The article briefly describes 14 excavation sites. All works were subject to a commercial contract. It allowed to research relatively substantial areas of the monument. Excavations were arranged in various parts of the historic development including periphery. The research of the periphery is unlikely under the scheduled works. The article describes how the monument was detected and studied and what findings were made. The study reveals how the archaeological finds correlate with the discovered records of the main owners of these mansions. Cultural Layer of Kurgan City archaeological monument is a unique source of information about the tangible culture of citizens in the mid–1700s through the early site 1900s. The paper reviews how the monument was explored through the prospective of particular finds, natural science researches, construction technologies and particular serial sites. The authors generalize the ceramic production, glass production and hygiene in the area. The article outlines the key problems associated with inadequate research of the Cultural Layer of Kurgan City and inferior comparison of archives and archaeological materials. The total area of the monument is 978 thousand sq. m. Yet, due to various reasons it annually loses several thousand square meters with no hope of return.

The Changing Landscape of Intravenous Thrombolysis for Acute Ischaemic Stroke

Intravenous thrombolysis remains the most accessible and effective reperfusion therapy available to patients with acute ischaemic stroke. Treatment with intravenous thrombolysis improves the odds of favourable functional outcome with the unacceptably low risk of haemorrhagic complications. Even in the current era of endovascular thrombectomy, intravenous thrombolysis remains the backbone of acute stroke treatment due to its accessibility and relative ease of administration. Since intravenous alteplase was first approved for acute ischaemic stroke in the mid 1990s, there have been significant advances in expanding the indication and time window for treatment, in addition to transitioning towards tenecteplase use for stroke thrombolysis. In this review, we will provide a narrative on the use of thrombolysis in acute ischaemic stroke including an up-to-date discussion on recent advances in thrombolytic therapy.

Tax Reforms and the Decline of the London Stock Market: The Untold Story

234 Various reasons have been put forward for the declining global relevance of the London equity market. Reform proposals and changes already implemented target some of the major problems identified as reasons for the stock market’s decline. Surprisingly, tax related explanations for the current state of the UK stock market are largely absent from the discourse. This paper argues that the preferential tax treatment of the dividend income of UK pension funds and insurance companies introduced in the early 1970s and repealed in the mid 1990s first contributed to the UK stock market’s growth by implicitly subsidising financing via equity and encouraging the flow of the funds of these investors into the market, and subsequently led to the market’s decline as a result of the outflow of the funds of the two major classes of institutional investors: UK pension funds and insurance companies. The key implication of this argument is that omitting tax as a major factor in the decline of the UK stock market risks ending up with reforms that can, at best, do little to change the current situation.

Epidemiology, Risk Factors, and Management of Biphasic Anaphylaxis.

Biphasic anaphylaxis is a variant of anaphylaxis characterized by recurrence of symptoms after initial resolution of anaphylaxis. It was first described in the mid 1990s by Popa and Lerner. Our understanding of the pathophysiology and epidemiology of the condition has advanced considerably since then. The purpose of this manuscript is to review the literature surrounding biphasic anaphylaxis while highlighting key works and recent advances. Prior studies have estimated biphasic anaphylaxis occurs in 0.4-20% of anaphylaxis episodes. The wide range may be related to differences in anaphylaxis diagnostic criteria which was inconsistent across studies. Recently identified risk factors for occurrence of biphasic anaphylaxis include severe initial symptoms including hypotension or hypoxia, delay in epinephrine use, and greater than one dose of epinephrine required to treat symptoms. Despite our progress to better understand biphasic anaphylaxis, there remain gaps in the literature. This article aims to review the recent literature including, epidemiology, risk factors, and management of biphasic anaphylaxis.

Remembering Australian Constitutional Democracy

For many years, historical accounts of Australian Federation ignored the distinctive ideological origins of the Australian Constitution. From the mid 1980s until the 2000s, however, a generation of historians remembered how the Australian drafters built a distinctive constitutional democracy that combined trust in parliament with a direct constitutional role for a plural ‘people’: the people of Australia and the people of the states. Drawing on Chartist and American ideas of popular sovereignty, this system of popular political constitutionalism textually guarantees that ‘the people’ can ‘directly’ choose both houses of parliament, break deadlocks between these houses and make constitutional law. The definition of ‘the people’ in this distinctive form of constitutional democracy was, however, racially exclusive. In particular, First Australians were excluded from the plural people of Australia. This intellectual history of the Australian Constitution, however, has had remarkably little impact on constitutional interpretation and discourse. This paper will begin the process of examining those implications. First, it will show how this history provides important contextual support and direction to the implied limitations on parliamentary power that stem from the constitution’s guarantee of representative democracy in sections 7 and 24 of the Constitution. Second, it will demonstrate how it aids in better understanding Australia’s unique constitutional system. To date, this system has remedied the racist roots of the original constitutional definition of the people largely through legislative reform. The constitutional recognition of First Australians is a critical step in acknowledging that First Australians are a distinct part of the plural Australian people. In the aftermath of the failure of the First Nations Voice to Parliament proposal, meaningful constitutional recognition for First Australians must address their structural exclusion from the plural Australian people.

A Brief Review of Investigations into Earth’s Temperature Since the Year 1800

For billions of years, natural processes alone, often working over millennia, drove Earth’s temperature and climate. For the last several centuries, human activities are a new driving force that is acting on a very short time scale. Knowing history helps chart necessary future actions with greater confidence. Since the end of the 17<sup>th</sup> century, investigations relating to Earth’s temperature and its climate have evolved from only scientific interest to also include practical concerns triggered by global warming. The early studies were relatively episodic with gaps of a decade or more common until the mid 20<sup>th</sup> century when they burgeoned starting with the International Geophysical Year. From the early to mid 1800s, to the early to mid 20<sup>th</sup> century, the investigations were at the initiation of the individual researchers. Starting in the mid 1950s, the investigations became more extensive, comprehensive and interrelated. Early researchers inferred that the atmosphere played a role in Earth’s temperature, and as far back as the 1850s it was concluded that higher CO<sub>2</sub> concentrations in the atmosphere could result in warming Earth. Later investigations provided information on the mechanism which established that atmospheric CO<sub>2</sub> concentration and its absorption and re-emitting of infrared radiation was a major factor in Earth’s temperature. Further, its increasing atmospheric concentration is a major driver of a warming globe at a rate far surpassing those detected in the geologic record. This paper traces the history of those researches based on the premise that knowing how we arrived at our current knowledge helps in supporting future research and actions to address the consequences of Earth’s warming.

Cristo Rey Schools and the Preferential Option for the Poor

Cristo Rey schools are a unique and distinctive form of Jesuit education. They have been very successful since the mid 1990s and are deemed to be coherent with Jesuit educational principles and the preferential option for the poor. They are only available to young people from low-income homes and are open to young people of all faiths and none. The Cristo Rey schools offer an intense and supportive environment for the students and prepare them for admission to college and university. Nevertheless, there are critiques of these schools that focus on: the financial model that means that the students must work one day a week; the nature of this work and questions about the ethical perspectives of the employers. There are further questions about cultural dissonance between the students and staff of the schools. This article explores the sociological and theological foundations of the Cristo Ray schools, evaluates their effectiveness and success and analyses the various points that are raised in the critique of these schools.

The fibula osteoseptocutaneous flap - evolution in concepts, techniques and technologies during mandibular reconstruction: a review

The fibula free flap has evolved from its initial description to be a reliable workhorse free flap providing bone, soft tissue, and reliable skin paddle. The senior author has been refining this technique since the mid 1980s and has personally performed over 950 hundred cases of the fibula free flap. The following paragraphs detail an evolution in surgical concepts related to this technique’s refinement and serves as a roadmap detailing contemporary mandibular reconstruction.

Administrative-territorial transformations in the Kursk region in the mid 1940s – early 1960s: main practices and results

Relevance. Issues of intraregional administrative and territorial transformations, including in the Kursk region, currently remain practically unstudied. This is due, on the one hand, to the specifics of the source base of the problem, which is a set of official legal documents, statistics and regulations, and, on the other hand, to insufficient interest on the part of researchers. Meanwhile, studying the specifics of the implementation of various administrative-territorial transformations in the post-war period using the example of a specific region has serious scientific significance: it allows us to detail the features of the socio-economic development of territories, demographic and migration aspects, etc., which creates the opportunity to take a slightly different look at history of the Kursk region.The purpose. Reveal the features of the dynamics of the administrative-territorial structure of the Kursk region in the mid-1940s – early 1960s.Objectives: based on the study of a complex of historical sources, show the prerequisites, logic and course of intraregional administrative and territorial transformations of the Kursk region in the period indicated above.Methodology. When writing the work, the authors relied on the fundamental methods of historical science (the principles of historicism and objectivity), as well as on a number of specific historical and general scientific methods (analytical, comparative historical, genetic, etc.).Results. Currently, in local historiography there are no scientific works on the history of the administrative-territorial structure of the Kursk region. The reference publications available to historians are replete with inaccuracies and errors. This work partly identifies these errors, and also shows the mechanisms for changing the administrative-territorial structure of the Kursk region in the mid-1940s – early 1960s.Conclusion. The administrative and territorial transformations that took place in the Kursk region in the mid1940s – early 1960s had a predominantly socio-economic basis. The rapid development of individual territories required changes in the network of village councils, districts, the creation of new regions, as well as the abolition of ineffective administrative-territorial units. The party and state leadership of the region and the country in most cases responded quite quickly to these needs, however, as practice has shown, not all of them were consolidated in practice.

Things, practices & policies: relationality and the early stages of the international promotion of Dutch design, 1920s–1970s

ABSTRACT This article takes a practice theory approach to explore the little-known history of the Dutch government practices that, between the early 1920s and mid 1970s, preceded explicit Dutch international cultural policy in organizing the promotion of the Dutch arts abroad. Advancing from an understanding of international cultural policy as a ‘hybrid’ (socio-material) practice of meaning production, it examines how those government agencies defined ‘Dutchness’ and ‘design’, and how the specificities of the things being promoted influenced those definitions. From this detailed empirical study, I propose a theorization of the relationship between policy, practices, and things as relational, meaning the understanding of things and policy as both shaping – and being shaped by – practices of international promotion. This theorization has broader relevance to cultural policy research since it suggests that policies and practices promoting different domains of culture may develop differently depending on the specificities of the artefacts that they seek to disseminate, and vice-versa.

Философия языка А.М. Деборина

The article is devoted to one of the little-known episodes of the scientific life of the famous Soviet philosopher Academician Abram Deborin. The author will analyze his works on linguistics. In the mid 1930s. Abram Deborin enthusiastically set about creating his own linguistic and philosophical concept of the origin of language and thinking on the basis of Nikolai Marr’s “New theory of language”. He developed and supplemented this doctrine, building a complete philosophy of language. Marr’s doctrine correlated with the Marxist-Leninist worldview of Abram Deborin, and also corresponded to his adherence to the doctrine of Hegel. The focus of the article is the book The New Doctrine of Language and Dialectical Materialism (1935), as well as his other works that deal with questions of linguistics. Developing the ideas of Marr, the Soviet philosopher strengthened his Marxist argument and resolved some of the contradictions of Marrism. He left aside the insignificant linguistic aspects of Marrism, which had nothing to do with philosophical problems. Abram Deborin became the first author of works on linguistics written from the standpoint of the “New theory of language”, and he was the only one to remain so. After the famous discussion on linguistics in 1950, when Joseph Stalin came out with the work Marxism and Problems of Linguistics, in which Marrism was crushed, Abram Deborin was forced to repent of his mistakes, demonstrating his rejection of the “New theory of language”. However, the scientist did not abandon the important idea of Nikolai Marr about the transition from synthetic thinking in primitive society to analytical thinking in class society. This idea was developed in his works at the junction of philosophy and linguistics, written after 1950. In this period particularly developed in his philosophy of language was the idea of the coincidence of opposite meanings in one word expressing some concept of the human protolanguage.

Differences in the Dynamics and Structure of Causes of Mortality in Neonatal and Post-Neonatal Neonatal Infants in the Krasnoyarsk Territory in the Late 1950s – mid 1980s

Differences in the Dynamics and Structure of Causes of Mortality in Neonatal and Post-Neonatal Neonatal Infants in the Krasnoyarsk Territory in the Late 1950s – mid 1980s

AUVs Under Ice: A Four-Decade Retrospective on Strategy and Risk Through the Autosub Looking Glass

Abstract Autonomous underwater vehicles (AUVs) have been used in the polar regions for decades. The technical challenges are well understood, and since the mid 1990s, missions of several hundred kilometers under sea ice have been possible. However, there remains a large gap between the endurance achieved in practice and the 1000+ km needed for large-scale sea ice studies; multiple, parallel sections under West Antarctic ice shelves; or sections under the Filchner-Ronne Ice Shelf. This retrospective examines how the U.K. Autosub program's requirements for under ice observations were determined and how those requirements helped build a strategy for a decade of technical progression and scientific achievement. At times progress was faltering, vehicle reliability was inadequate and the approach to risk management was reactive rather than proactive. New analytical tools, some controversial, were developed to assess and manage risk and to drive improvements. While new satellite techniques arguably reduced the need for deployments under sea ice, they remain the only effective solution to fill data-gaps in bathymetry and ocean/ice interactions under ice shelves. The challenge for international collaboration is to accelerate the development of robust and reliable vehicles. The first task remains to survey the basic geometry of the key Antarctic ice shelf cavities. Taking a decadal view, AUV capability should expand to be capable of yearlong deployments under critical ice shelves.

‘Development Has Gone Crazy’: The Gujarat Model of ‘Unequal’ Development through Neoliberalism and Hindutva

Since the mid 1990s, the western Indian state of Gujarat has been continuously led by the Bharatiya Janata Party (BJP), a Right-wing Hindu nationalist political party. The BJP has aggressively pursued Right-wing religious ideologies, while, on the economic front, it has taken on board neoliberal policies. The outcome of this mix came to be referred to as the ‘Gujarat model of development’, as the state delivered impressive figures in the economy, although at the cost of human development indices. The article shows that the intensified adoption of Hindutva and neoliberalism has resulted in unequal development across regions, sectors of the economy and industries, as well as across the axes of class, caste and religion. As unequal development is inherent in both the ideologies of neoliberalism and Hindutva, each of them further exacerbates societal inequalities across multiple spheres without addressing these.