The sorption of uranium on standard Nano magnesium hydroxide was studied. Nanoparticles Mg(OH)2 was prepared from bittern via the precipitation process. The pilot nano magnesium hydroxide was calcined at 300 °C for 3 hours to remove some byproducts such as chlorartinite and hydromagnesite. The structure, morphology, and chemical composition of standard nano Mg(OH)2 Mg(OH)2-st, pilot Mg(OH)2, and calcined pilot Mg(OH)2 were characterized using XRD, SEM, EDX, Raman and TEM. Adsorption of standard Mg(OH)2 was described by the Langmuir model, whereas kinetics was investigated using pseudo-second-order models. Mg(OH)2 calcined at 300 °C showed the highest uranium uptake at 217 mg/g. This was reached at pH 4, contact time of 20 min, solid-to-liquid ratio of 10 g/L, and uranium initial concentration of 875 mg/L at 20 (±2)°C, this could be explained by the increase of pore volume and surface area. Desorption of Uranium ions from loaded Mg(OH)2-st particles was performed in a batch mode. Elution efficiency reached about 100% using 0.5 molL−1 H2SO4 and 15 minute contact time.