Assisted Method Research Articles

Preparation and characterization of soluplus-based nanosuspension for dissolution enhancement of indomethacin using ultrasonic assisted precipitation method for formulation and Box-Behnken design for optimization

Objectives Nanosuspensions are increasingly recognized as a valuable technology for enhancing poorly water-soluble drugs’ solubility and dissolution rate, thereby improving their bioavailability. In this study, we employed ultrasonic-assisted precipitation to fabricate nanosuspensions of indomethacin (IND), utilizing Soluplus® (Sol) as a stabilizing agent. Our objectives were driven by hypotheses centered on optimizing formulation variables and developing predictive models for optimal IND formulations. Significance This research highlights the Box-Behnken design (BBD) as a powerful tool that optimizes the properties of IND nanosuspensions, thus significantly enhancing their dissolution rate. Methods The impacts of the independent variables on the mean particle size (MPS), polydispersity index (PDI), and zeta potential (ZP) were investigated using BBD. The optimized nanosuspension was freeze-dried with 3% trehalose to produce a dry nanosuspension (DNS). The DNS was characterized by SEM, DSC, XRPD, solubility, and dissolution. Results The IND: Sol ratio and sonication power significantly affected the MPS and ZP of the nanosuspensions. The optimized formulation showed MPS, PDI, and ZP of 144.77 ± 6.68 nm, 0.26 ± 0.08, and −24.6 ± 1.90 mV, respectively. The DNS exhibited spherical particle morphology. The DSC and XRPD confirmed the amorphous state of IND with enhanced solubility and dissolution of IND. DNS showed a 3.7-fold increase in drug release in the first 15 min compared with raw IND. Conclusions This study demonstrated the critical role of BBD in accurately predicting the values of independent variables essential for formulating optimal nanosuspensions. These formulations possess specific properties that can be effectively integrated into various dosage forms tailored for different routes of administration.

Oriented Bi2Te3-based films enabled high performance planar thermoelectric cooling device for hot spot elimination

Film-thermoelectric cooling devices are expected to provide a promising active thermal management solution with the continues increase of the power density of integrated circuit chips and other electronic devices. However, because the microstructure-related performance of thermoelectric films has not been perfectly matched with the device configuration, the potential of planar devices on chip heat dissipation has still not been fully exploited. Here, by liquid Te assistant growth method, highly (00 l) orientated Bi2Te3-based films which is comparable to single crystals are obtained in polycrystal films in this work. The high mobility stem from high orientation and low lattice thermal conductivity resulting from excess Te induced staggered stacking faults leads to high in-plane zT values ~1.53 and ~1.10 for P-type Bi0.4Sb1.6Te3 and N-type Bi2Te3 films, respectively. The planar devices basing on the geometrically designed high orientation films produce a remarkable temperature reduction of ~8.2 K in the hot spot elimination experiment, demonstrating the great benefit of Te assistant growth method for oriented planar Bi2Te3 films and planar devices devices design, and also bring great enlightenment to the next generation active thermal management for integrated circuits.

Психологическая работа с сотрудниками органов внутренних дел Российской Федерации, выполняющими служебные обязанности в особых условиях

The problem of psychological work with employees of the internal affairs bodies of the Russian Federation at all stages of their official duties in special conditions is considered. The goal is to develop and test methodological recommendations for conducting psychological work with employees of the internal affairs bodies of the Russian Federation performing official duties in special conditions. Materials and methods. The total sample of the study consisted of 244 people aged 21 to 55 years from among psychologists of the Ministry of Internal Affairs of the Russian Federation, the National Guard and the Ministry of Defense. Psychological conversations were conducted with psychologists from internal affairs bodies and other law enforcement agencies. A survey of psychologists from the internal affairs bodies of the Russian Federation was conducted to identify the main problems of psychological work with employees of the internal affairs bodies of the Russian Federation who performed official duties in special conditions. The methodological recommendations developed as a result of the study underwent expert evaluation. The expert group was formed from among the most experienced psychologists of the internal affairs bodies of the Russian Federation. Results and discussion. According to the survey results, it was revealed that: 96% of the psychologists surveyed have experience working with employees after they have completed official tasks in special conditions; 53% of psychologists surveyed have experience working with employees who have been injured, traumatized, disfigured and 43% with members of their families; significantly fewer psychologists have experience working with family members of employees who died in the line of duty (10%); only 5% of the surveyed psychologists have experience in providing emergency psychological assistance to employees in the process of performing operational and official tasks in special conditions. Also, based on the results of the survey, the most effective methods of psychological assistance to employees of the internal affairs bodies of the Russian Federation were determined during and after the performance of their official duties in special conditions, as well as the most effective methods of providing psychological assistance to members of their families.

Kirschner wire intramedullary fixation combined with improved nice knot-end cerclage temporarily fixation-assisted reduction before plate osteosynthesis in treating displaced and comminuted clavicle fractures

Background and objectiveNice knots have been used as an assisted reduction technique in surgery for displaced and comminuted fractures. This study aims to investigate the clinical efficacy of Kirschner wire intramedullary fixation combined with improved Nice knot-end cerclage temporarily fixation-assisted reduction before plate osteosynthesis in treating displaced and comminuted clavicle fractures.MethodsA retrospective study selected 210 patients with comminuted displaced clavicle fractures (January 2017–December 2020) in our hospital. The patients were divided into two groups via the fracture reduction method: the observation group (intramedullary Kirschner’s wire fixation combined with modified Nice node-to-end cerclage temporarily fixation-assisted reduction; n = 42) and the control group (including four subgroups with 42 cases in each subgroup, with assisted reduction methods of clamp fixation, screw fixation, square knot fixation and Kirschner wire fixation; each subgroup n = 42). The operation time, intraoperative bleeding, visual analogue scale (VAS) score at 24 h after the operation, healing time, postoperative limb functional activities, patients’ self-perception, subjective satisfaction and shoulder joint function were compared.ResultsThe operation time and the intraoperative blood loss of the observation group was significantly lower than that of each subgroup in the control group (p < 0.05). The VAS score of the observation group 24 h after the operation was significantly lower than that of each subgroup in the control group apart from the screw fixation group (p < 0.05). The Neer score of the observation group was significantly higher than that of each subgroup in the control group apart from the square knot fixation group (p < 0.05). The square knot is relatively better than the other four methods. Patients were generally satisfied with the modified Nice treatment.ConclusionThe use of a Kirschner wire intramedullary fixation combined with improved Nice knot-end cerclage temporarily fixation-assisted reduction before plate osteosynthesis in treating displaced and comminuted clavicle fractures can achieve satisfactory postoperative clinical results.

Enhanced Degradation of Norfloxacin Under Visible Light by S-Scheme Fe2O3/g-C3N4 Heterojunctions.

S-scheme Fe2O3/g-C3N4 heterojunctions were successfully fabricated by the ultrasonic assistance method to remove norfloxacin (NOR) under visible light irradiation. The synthesized catalysts were well studied through various techniques. The obtained Fe2O3/g-C3N4 heterojunctions exhibited an optimal photocatalytic degradation of 94.7% for NOR, which was 1.67 and 1.28 times higher than using Fe2O3 and g-C3N4 alone, respectively. In addition, the kinetic constant of NOR removal with Fe2O3/g-C3N4 composites was about 0.6631 h-1, and NOR photo-deegradation was still 86.7% after four cycles. The enhanced photocatalytic activity may be mainly attributed to the formation of S-scheme Fe2O3/g-C3N4 heterojunctions with built-in electric fields, which were beneficial to the separation and transfer of photostimulated charge carriers. Furthermore, a possible photo-degradation mechanism of NOR for S-scheme Fe2O3/g-C3N4 heterojunctions is described.

Bi-phenyl derived hyper-crosslinked polymer as a metal-free adsorbent for the removal of pharmaceuticals from water

The global concern of emergent aquatic pollutants, especially pharmaceutical contaminants, emphasizes the necessity for metal-free adsorbents to tackle water contamination issues. In this direction, a biphenyl-derived hyper-crosslinked polymer (poly-biph) was utilized as an adsorbent for the removal of ciprofloxacin (CPX) and doxycycline (DOX) from water. Micro-mesoporous hyper-crosslinked polymeric adsorbent (poly-biph) was synthesized by using bi-phenyl as precursor and formaldehyde dimethyl acetal (FDA) as crosslinker via microwave assisted method. It exhibits specific surface area (SABET) and pore volume of 1088 m2/g and 1.3 cm3/g, respectively. The spectral analysis confirmed the successful crosslinking of biphenyl with the linker FDA. The sorption efficiency of metal-free poly-biph for CPX and DOX was evaluated via batch and continuous flow modes under various operational parameters. poly-biph exhibited swift removal efficiency (>80 %) for CPX and DOX within a min. The batch mode sorption modeling revealed a chemisorption process and remarkable maximum sorption capacity of 470.8 and 425.1 mg/g for CPX and DOX, respectively. The continuous-flow studies of poly-biph revealed the better applicability of the Clark kinetic model with a maximum bed capacity of 313.5 and 372.4 mg/g for CPX and DOX, respectively. Synergistic mechanisms, including π-π interaction, electrostatic interaction, and pore-filling effect, were found to be the main driving forces for the sorptive removal of CPX and DOX onto poly-biph. The findings indicated that poly-biph possesses the ability to effectively eliminate DOX and CPX from the aquatic environment.

PENGEMBANGAN USAHA PADA UMKM YU MIN BATIK &amp; BUTIK DESA SIDOREJO KECAMATAN COMAL KABUPATEN PEMALANG

&lt;table width="576" border="1" cellspacing="0" cellpadding="0"&gt;&lt;tbody&gt;&lt;tr&gt;&lt;td width="402"&gt;&lt;p&gt;The Micro, Small and Medium Enterprises that are the object are the UMKM Yu Min Batik &amp;amp; Boutique owned by Mrs. Siti Aminah which is located in Sidorejo Village, Comal District, Pemalang Regency. This MSME operates in the field of clothing and modified batik cloth in Pemalang. The aim of implementing this activity is to develop business, good financial management and production performance. The business assistance provided includes marketing aspects. The efforts made by the accompanying team aim to promote Yu Min Batik &amp;amp; Boutique products through MSME activities such as bazaars and catalog content on online social media. This is due to increasingly sophisticated technological developments and seeing many entrepreneurs, especially MSMEs, promoting their businesses through online social media. The aim is to introduce and attract the interest of potential customers by understanding the individual characteristics of consumers so that the products sold will match their wishes.&lt;/p&gt;&lt;p&gt;The assistance method used is carrying out several programs such as making banners, making simple bookkeeping, Google maps, participating in MSME bazaar activities, making direction boards, making organizational structures, business profiles, and creating social media (Instagram). After analyzing and applying the program to Yu Min Batik products, it produced a positive impact on MSME owners. Such as introducing products through promotions on social media and placing banners, organizational structures, understanding simple bookkeeping, business profiles, and installing direction boards to fulfill product requirements to support promotions so that people have more confidence in the products they want to buy.&lt;strong&gt;&lt;/strong&gt;&lt;/p&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/tbody&gt;&lt;/table&gt;

Evaluation of male reproductive hormones of Kalahari Red and Kalawad goat bucks as affected by age and season under tropical conditions.

Comprehensive understanding of reproductive hormones and environmental cues with their relationship is essential for efficient production in livestock sectors involving either assisted or natural reproductive methods. This study evaluated the effects of age and seasonal-associated changes in the blood concentrations of testosterone and follicle stimulating hormone (FSH) of male Kalahari Red (KR) andKalawad(KW)-crossbred goats. Based on a 2 × 3 × 4 factorial arrangement, a total of 42 bucks (KR n = 21 and KW n = 21) were allotted into three age groups (> 1 ≤ 2years, > 2 ≤ 3years and > 3 ≤ 4years) with seven KR bucks and seven KW bucks each per age group; reared under different seasons (early rainy, late rainy, early dry and late dry). The animals were managed semi-intensively, kept in an open-ventilated pen and subjected to same nutritional regime throughout the one-year experimental period. Follicle stimulating hormone and testosterone concentrations were analyzed in serum samples. Data obtained reproductive hormones were subjected to three-way Analysis of Variance using SAS 1999. Results show that breed had a significant effect (p < 0.05) on both serum FSH and testosterone concentrations. The highest FSH (0.49 ± 0.02ng/mL, 0.45 ± 0.01ng/mL, 0.41 ± 0.1ng/mL and 0.47 ± 0.07ng/mL) mean values (P > 0.05) were observed in KR in September, October, November and May, respectively while the highest (2.6 ± 0.02ng/mL) testosterone concentration in KW (p < 0.05) was obtained in December. Testosterone had irregular patterns between breeds and months of sampling. FSH was at peak (p > 0.05) in KR during the late rainy season at all ages while the values of FSH concentration in KW were not significantly different at all ages and seasons. The highest (2.05 ± 0.11ng/mL) serum testosterone mean value in KW peaked (p < 0.05) age > 3 ≤ 4years during the late rainy season. Testosterone concentration was lower and steady at all ages during rainy seasons in KR but started fluctuating during the early dry season. The least mean (0.62 ± 0.07ng/mL and 0.68 ± 0.05ng/mL) were recorded (p > 0.05) in KW during the late dry season at age > 2 ≤ 3 and > 3 ≤ 4years respectively. In KR and KW goat breeds raised under tropical condition, the high seasonal variations were responsible for the fluctuations in the reproductive hormones which resultantly altered or lowered the sexual activity of the animals at certain season(s).

Oiling out and solubility measurement, molecular simulation and thermodynamic properties of d-tagatose in four aqueous binary solvent systems at 283.15 to 323.15 K

Solubility of D-Tagatose in four aqueous binary solvent systems from 278.15 K to 323.15 K was determined using the anti-solvent assisted gravimetric method. The solubility increases with temperature in all four binary solvents, with water, a good solvent, exhibiting a similar trend. In addition, the dissolution process generally follows the ’like dissolves like’ rule. The study indicates that the oiling out occurs when water exhibits a high molar fraction in water + 1-propanol, and water + isopropanol. Furthermore, we study the charge of the molecule using the molecular electrostatic potential surface (MEPS), aiming to analyze the molecular interactions. Then, to explain the dissolution behaviors of D-tagatose, the radial distribution function (RDF) by molecular dynamics simulations (MD) revealed a strong correlation between solute–solvent interactions and solubility, with significant solvent–solvent interactions. The solubility data was correlated using the modified Apelblat equation, Van’t Hoff equation, λh equation, and Jouyban-Acree model, with demonstrating the high consistency in the data. Finally, the thermodynamic properties revealed that the dissolution process of D-Tagatose is endothermic, and entropy-driven based on all positive values for ΔsolHo, ΔsolSo, ΔsolGo.

An adaptive assisted method based on MOPSO for THz MMA effective designing

Abstract To address the high time cost and low efficiency of traditional terahertz metamaterial absorber design, an adaptive method based on multi-objective particle swarm optimization was proposed. First, we presented a symmetric absorber of a four-split-ring resonator with a cross-shaped top layer. The structural parameters were optimized by the particle swarm optimization and multi-objective particle swarm optimization algorithms. The simulation results indicated that the multi-objective particle swarm optimization rapidly obtained geometric parameters that balance the high absorptivity and high quality factors. This method quickly identified a symmetric structure with absorptivity greater than 99% and quality factor of 377.45 at 1.584 THz. Additionally, the asymmetric structure achieved near-perfect absorption at 1.585 THz with a Q value of 281.32. By studying the electric field distribution and the surface current distribution, the physical mechanism of the absorber designed has been explained. This adaptive assisted method based on multi-objective particle swarm optimization can efficiently design metamaterial absorbers and offer an artificial intelligence strategy for terahertz functional device design.

Ultra-sensitive liquefied petroleum gas (LPG) sensor based on monometallic Ag nanospheres synthesized via microwave-assisted facile approach

We present the synthesis, analysis, and utility of polyvinylpyrrolidone (PVP) stabilized monometallic silver nanospheres for liquefied petroleum gas sensing at room temperature. We have synthesised silver nanospheres (Ag-NSs) in the diameter range of 13–21 nm using a microwave assisted method, which is both easy and fast, because microwave irradiation only takes 30 s. A solution of 0.1 M silver nitrate (AgNO3) in an ethanolic medium was microwave-irradiated to produce Ag-NSs. PVP was used as a stabilising agent throughout the process. Spin coating method was used to produce thin films of synthesised monometallic Ag-NSs. X-ray diffraction (XRD), scanning electron microscopy (SEM), acoustic particle sizer (APS), UV–visible absorption (UV–visible) and Fourier Transform Infrared (FT-IR) spectroscopy were used for characterising Ag-NSs. Based on the acoustic attenuation of the prepared sample, the acoustic particle sizer estimated the diameter of Ag-NSs to be around 17 nm. The deposited films were examined for LPG leakage detection at ambient temperature. This is the first report on monometallic Ag-NSs for leakage detection of LPG at room temperature operation below its lower explosive limit (LEL). The significant finding of the developed sensor is that it prompts the quick response (∼16 s) and recovery (∼64 s) as Ag enhances the reaction rate between the sensing film surface and adsorbed LPG, thereby, augments the sensitivity of sensor even below LEL. Moreover, the fabricated LPG sensor shows noteworthy reproducibility (measured up to six cycles) and stability up to 06 months after fabrication.

A self-supervised assisted label-efficient method for online remaining useful life prediction

Remaining Useful Life (RUL) prediction is crucial for safe and efficient production in industrial equipment. Conventional methods struggle in online environments, facing challenges like data distribution differences across working conditions, model cold start problem under new equipment, and lack of labels in online scenarios. To address these challenges, we propose a novel framework for online RUL prediction that leverages knowledge from self-supervised tasks via metric learning. First, a label-efficient self-supervised learning method incorporating soft triplet loss is proposed to transfer degradation knowledge. Second, we develop a two-stage method to distinguish different degradation stages of the equipment for better alignment of data distribution. Third, we introduce a pseudo-label dynamic self-updating strategy and a sample entropy-based data replay strategy, fine-tuning the offline model with newly acquired data. Our method outperforms state-of-the-art unsupervised approaches, reducing RMSE and MAPE by 16.02% and 8.40%, respectively, and achieves performance comparable to supervised methods.

Penerapan Green Economy terhadap Kelompok Tani Hortikultura melalui Konsep Zero Waste System Masyarakat Desa Pogalan, Magelang

The residents of Pogalan Village are dominated by farmers, making the application of a green economy able to develop agriculture. In the short term, the focus of this program is to increase revenue through the concept of a zero waste system. The implementation of this Community Partnership Program is located in Pogalan Village, Pakis District, Magelang Regency. This community partnership program is carried out using the methods of socialization, education, tutorials or continuous assistance and focus group discussions. The results obtained are the understanding of farmer groups in using a zero waste system to get to a green economy. The advantage of a zero waste system has various advantages including converting waste into natural products that are environmentally friendly. Wono Mulyo farmer groups can utilize the existing waste so that it can be reused and has economic value. Community service activities are expected to continue by the Wono Mulyo farmer group to overcome other problems experienced such as marketing problems and problems in processing crops.

Systematic review of ultrasound-guided central venous catheter placement-related complications in neonates and infants aged

Although ultrasound can be considered an assistant method, successful placement of a central venous catheter (CVC) in infants is still challenging. The incidence of CVC placement-related complications is still high. Therefore, this systematic review aimed to synthesize evidence to assess the effects of ultrasound-guided CVC placement on adverse outcomes in infants and neonates aged <12 months. PubMed, Ovid, EMBASE, and the Cochrane Library were searched to identify potentially relevant studies. The main outcome was the incidence of adverse events, which included inadvertent arterial puncture, hematoma, pneumothorax and hemothorax, catheter kinking, threading, and malpositioning problems, venous thrombosis, catheter-related infection, phlebitis, and cardiac tamponade. Eleven studies involving 2097 patients were included in the final analysis. The odds of inadvertent arterial puncture, and catheter kinking, threading, and malpositioning problems were lower in the ultrasound group than in the control group. No significant difference was detected in the incidence of hematoma or venous thrombosis between the control and ultrasound groups. Other complications, such as pneumothorax, hemothorax, phlebitis, and cardiac tamponade, rarely occurred. Ultrasound-guided CVC placement can improve the safety of punctures in neonates and infants. CVC punctures should be guided in real-time by ultrasound.

Modulating optical and electrical properties of chemically synthesized ZnMn2O4 nanoparticles through crystallinity: Integrating theoretical and experimental insights

Theoretical and experimental analyses of zinc manganite (ZnMn2O4) nanoparticles were carefully conducted for in-depth exploration of their electronic and optical properties. Nanosized particles, approximately 11–15 nm in size, were synthesized using a post-sintering assisted co-precipitation method. Theoretical calculations using Rietveld refinement were conducted to accurately predict crystal parameters and simulate XRD patterns consistent with experimental XRD observations. UV–visible absorption spectra and Tauc plot analysis indicated a bandgap ranging from 0.65 to 0.79 eV, while photoluminescence spectra revealed the most intense peak at 466 nm, possibly arising from exciton recombination processes or defect-related emissions. Density function theory (DFT) calculations were employed to compute the band structure and density of states of ZnMn2O4, resulting in a calculated bandgap of 0.73 eV, which aligned closely with the experimental findings. Moreover, DFT calculation identified atomic-level transitions responsible for absorption peaks in the material. Comprehensive evaluations of the mechanical and optical properties, integrating theoretical insights with experimental data, provided a holistic understanding of the intricate electronic and optical characteristics of ZnMn2O4. Furthermore, frequency and temperature-dependent dielectric properties demonstrated the MWS-type polarization effect. Besides, the activation energy of 0.582–0.553 eV, calculated using the Arrhenius plot, was good in accordance with our dielectric analysis, solidifying the potential of this nanomaterial for advanced optoelectronic applications.

DECENTRALIZED PLATFORM FOR FINANCING CHARITY PROJECTS

The rapid development of new technologies, together with the emergence of new military conflicts and humanitarian crises, creates the need for quick response and the introduction of new methods of effective assistance to the affected population and the restoration of damaged territories. Decentralized charity became one of these methods of assistance. To implement the task, the latest technologies were used, which combine maximum transparency and complete security when forming and working with charitable payments. The main technologies that were used: blockchain and smart contracts on it, protocols of liquidity pools and profitable farming, as well as web development technologies for creating a web application. The research analyzed existing approaches, methods of software solutions for financing decentralized charity; developed and improved the mathematical model and architecture of the software application. A system of smart contracts was created using additional administrative modules, and on its basis, a decentralized charitable platform for assistance to Ukraine was implemented in the form of a web application. Such a decentralized system can be freely used and implemented nowadays to finance the most necessary charitable projects of our country with crypto-assets in various spheres: humanitarian, social or in matters of security and weapons.

시각장애인의 박물관 관람을 위한 감상 보조 방법 적용 연구

The purpose of this study is to evaluate appreciation assistance methods of 3D model printouts and audio explanations of four historical relics for blind people. As a result, five participants with visual disabilities recognized the main elements through appreciating 3D model printouts and audio explanations of historical relics. The participants responded that they were satisfied with being able to directly appreciate tactile objects from the historical relics. Also, they were satisfied that they learned about the parts of the 3D model printouts and historical backgrounds with audio explanations. Otherwise they could not know them with only tactile method. Through this study, we presented suggestions to address when providing assistance methods to appreciate historical relics for people with visual disabilities in museums. Future research is needed to make guidelines that take into account various factors that arise when museums provide appreciation assistance methods for those with visual disabilities.

Methods of Psychological Assistance in Patients with Facial Nerve Damage

Methods of Psychological Assistance in Patients with Facial Nerve Damage

Family assistant – a modern form of support for multiproblem families

People frequently perceive family as, to quote Anthony Giddens, “the refreshing source of joy, warmth, love andaffection” (Giddens, 2005, s. 196). However, a family can be also the scene of loneliness, violence, and mental insecurity; it may not be able to cope with fulfilling its basic social roles. Such family should be cared for by institutional aid and support, as well as by professional family assistants. Since 2012 families may count on a family assistant in the course of overcoming their life struggles. Even though this profession has been present on our market already for 10 years, its organizational context still needs to be clarified. In particular, there are significant issues referring to the family assistant qualifications, competence, methods, tools, and workroom. The article aims mainly at pointing out to the specific role of the family assistant and to the preferred competence and skills required for this profession.

Rich surface oxygen vacancies SmFeO3 for acetylene gas sensor with ppb-level detection

The concentration of acetylene (C2H2) is a key parameter to monitor the status of oil-immersed transformers. When the transformer is operated at 330 kV, the transformer oil dissolving 1 ppm of C2H2 is considered as red flag. Therefore, low detection limit of C2H2 is very necessary for transformer monitoring systems. In this work, a freeze-dry assisted sol-gel method is proposed to synthesize rich surface oxygen vacancies SmFeO3. Compared to the traditional sol-gel method, the freeze-dry synthesized SmFeO3 exhibits the increased oxygen vacancies and a higher proportion of larger pores (>100 nm). The response of the sensor based on above SmFeO3 (SFO-F) to C2H2 is higher than that of the sensor based on SmFeO3 synthesized by traditionally sol-gel method (SFO-S), and the SFO-F exhibits the low detection limit of 200 ppb C2H2. In addition, the response time for 200 ppb C2H2 of the SFO-F is relatively smaller than that of the SFO-S. Moreover, the sensors exhibit a high selectivity towards C2H2 in comparison to other gases (C2H4, CH4, NO, CO, H2), and five consecutive test cycles demonstrate the high stability of the sensors. The SmFeO3 prepared through freeze-drying may provide a viable approach to enhance the performance of C2H2 sensors and presenting a fresh perspective to fabricating oxygen-rich vacancy materials.