Method Of Relief Research Articles

Suboptimal lipid lowering therapy after percutaneous coronary intervention and impact on 1 year outcomes: data from a large contemporary PCI registry

Abstract Background Myocardial revascularisation by percutaneous coronary intervention (PCI) is an effective method for symptom relief in obstructive coronary artery disease on top of pharmacological therapy. In patients with an acute coronary syndrome (ACS), revascularization also leads to improved prognosis. However, patients who underwent PCI are still at high risk for future coronary events such as myocardial infarction, in-stent restenosis or development of new lesions at other locations. According to the current ESC guidelines every patient undergoing PCI should receive at least high-intensity statin therapy to achieve low density lipoprotein cholesterol (LDL-C) target values and to prevent future coronary events. The Zuid-Oost Netherlands Heart Registry (ZON-HR) is an ongoing, multicentre, prospective registry designed to improve secondary prevention after PCI. Purpose To describe differences in lipid lowering therapy after PCI and the influence on major adverse cardiovascular and cerebral events (MACCE) one year after PCI. Methods Since November 2020 data from all patients who underwent PCI in one of the four ZON-HR hospitals were included. Patients with known lipid lowering medication at discharge and 1 year follow-up were selected (N=4272). Patient characteristics, lipid lowering medication at discharge and 1 year follow-up regarding complications were collected. Cross tables and logistic regressions were used to observe baseline differences between patients with and without lipid lowering therapy (LLT) at discharge. A cox regression survival analysis with adjustments for baseline differences was performed to look at differences in MACCE after one year in patients with and without LLT after discharge. Results In 11.9% of the patients LLT was not part of the discharge medication. Patients without LLT were older and had more often chronic coronary syndrome (71.3 ± 10.7 vs 67.6 ± 10.9 and 63.2% vs 43.1%, respectively)(table 1). After one year, MACCE had occurred more often in patients without LLT at discharge after adjustment for baseline differences (HR: 1.51, 95% CI 1.15-1.98) (figure 1). In an additional analysis with only ACS patients even a higher occurrence of MACCE was observed in patients without LLT at discharge (HR: 1.97, 95%CI 1.41-2.76). Conclusion In real-world practice, suboptimal cholesterol management is frequently observed and leads to a higher occurrence of MACCE one year post PCI. Almost 12% of the patients did not have any LLT after PCI. Patients with ACS indication for PCI without LLT after PCI even had worse outcome regarding MACCE after 1 year. More attention should be paid regarding cholesterol management after PCI in order to prevent future coronary events.Baseline differencesMACCE and lipid lowering medication

Investigating the Effects and Mechanisms of Thermal–Vibration-Coupled Stress Relief Treatment on Residual Stress in SiC/Al Composites

Aluminum matrix composites reinforced with particles (PRAMCs) frequently develop considerable residual stresses post-quenching, which can negatively affect fatigue life and dimensional accuracy. Traditional stress relief methods for aluminum alloys are only partially effective. This study examined thermal stress relief (TSR), vibratory stress relief (VSR), and a combined thermal–vibratory stress relief (TVSR) approach for SiC/Al composites. All treatments proved successful in diminishing residual stresses, with the most significant reduction along the direction of peak dynamic stress. Additionally, this study analyzed micro-residual stresses via a macro–micro-residual stress finite element model to understand differences in stress relief outcomes. Optimizing the TVSR process could be key to more effectively reducing residual stresses in SiC/Al composites.

Beware of the Dark Side: The Rise of Cybercrimes

This study paper offers a top to bottom assessment of the mind boggling hardships introduced by cybercrime in India, pushed by the country's quick digitalization in different areas. The expansion in cybercrime occurrences, enveloping monetary extortion, information breaks, and cyberattacks, has arisen as a critical concern for partners in both public and business areas. This report investigations the essential drives executed by the Indian government, policing, and business elements to counter these difficulties. It inspects the developing complexities of digital dangers, evaluates the viability of current relief methods, and proposes thoughts for making a more adaptable and powerful network protection structure. The report offers fundamental bits of knowledge to upgrade India's safeguard against the raising scene of computerized dangers by tending to the essential causes and advancing nature of cybercrime in the country. The discoveries look to further develop India's online protection foundation and reinforce strength against expanding digital dangers.

Comparison of the thermal and vibrational stress relief methods in terms of mechanical and metallurgical aspects of rolled AA2024 specimens

Comparison of the thermal and vibrational stress relief methods in terms of mechanical and metallurgical aspects of rolled AA2024 specimens

Virtual reality as a promising method of pain relief in patients with venous leg ulcers.

Pain in patients suffering from hard-to-heal wounds is a serious problem that hinders the healing process and affects their quality of life. Virtual reality (VR) is increasingly being used for pain relief. The aim of the study was to assess whether the use of VR during mechanical cleansing of venous leg ulcers would result in a reduction in patients' pain. Sixty patients were randomly divided into two groups. The experimental group included patients who used VR goggles during wound cleansing, and the control group included patients who did not use such equipment during wound cleansing. The Oculus Quest 2 VR Goggles were used in the experiment. After wound cleaning, the patient assessed the intensity of his pain on a numerical pain rating scale from 0 to 10 points. The difference between the intensity of pain during wound cleansing in patients from the experimental and control group turned out to be statistically significant (p < 0.001). It was on average 1.13 ± 0.68 points in the experimental group, and in the case of people from the control group, it was 4.73 ± 1.2 points. To conclude, the use of VR in patients with venous leg ulcers reduces pain during wound cleansing.

Knowledge, attitude and practice toward to artificial intelligent patient-controlled analgesia among anesthesiologists: a cross-sectional study in east China’s Jiangsu Province

BackgroundInadequate postoperative analgesia greatly affects the recovery of patients, can poses a substantial health and economic burden. Patient-controlled analgesia is the most commonly used method for postoperative pain relief. However, the situation of inadequate analgesia still exists. Artificial intelligent Patient-controlled analgesia (Ai-PCA) system can make it easier for medical staff to understand the pain level of patients in order to deal with it in time. So far, several studies have investigated anesthesiologists’ knowledge and management of Ai-PCA.ObjectiveThis study aimed to assess the degree of anesthesiologists’ knowledge, attitude and their practice (KAP) towards Ai-PCA in east China’s Jiangsu Province.MethodsThis cross-sectional study was conducted among 396 anesthesiologists working in tertiary hospitals. The data were collected using a pretested, structured and self-administered KAP questionnaire. The data were analyzed using Independent t-test, analysis of variance, Pearson’s correlation and multiple linear regression tests.ResultsFive hundred twelve questionnaires were collected, 396 anesthesiologists (190 Male, and 206 Female) were included in our study for statistical analysis. The score of knowledge, attitude, practice was 5.49 ((SD = 1.65; range:0–8), 37.45 (SD = 4.46; range:9–45), and 26.41 (SD = 9.61; range:9–45), respectively. Among the participants, 309 (78%) and 264 (66.7%) had good knowledge and positive attitudes toward Ai-PCA, respectively. However, only 81 (20.5%) of the participants exhibited good practice regarding Ai-PCA. Participation in Ai-PCA training showed a significant correlation with knowledge, attitude and practice scores. Besides, age, years of experience and professional titles of anesthesiologists were correlated with knowledge scores. The title of the anesthesiologist was associated with attitude scores. And the marital status of anesthesiologists was correlated with practice scores.ConclusionOur findings revealed the score of practice regarding Ai-PCA are very poor among anesthesiologists in east China’s Jiangsu Province. The utilization of Ai-PCA was found to be impacted by whether the individual had received training. This calls for a comprehensive approach should be conducted for raising the level of knowledge, attitude, and practice of anesthesiologist on using Ai-PCA and more Ai-PCA training to be included in the daily learning.Trial registrationChinese Clinical Trial Registry (www.chictr.org.cn; 27/10/2023; ChiCTR2300077070).

A summary of pain and pain-related variables in the Avon Longitudinal Study of Parents and Children.

To study pain, data on pain characteristics, possible triggers and consequences - such as the impact of pain on people's lives - need to be available. When not collated, described and/or organised in a systematic manner, it can be difficult to assess how useful an existing dataset may be for one's project. This data note describes and categorises the complex and multi-modal indices of pain available in the Avon Longitudinal Study of Parents and Children (ALSPAC). Data from two generations of the ALSPAC cohort; index child participants (Generation 1, G1), their mothers and fathers/mothers' partners (Generation 0, G0) were used. Search terms such as 'pain', 'ache', 'hurt', 'sore', specific pain conditions, labour pain and methods of pain relief were used to identify pain and pain-related variables. These data were extracted from all waves of data collection. We developed pain categories and subsequently categorised variables in an iterative process. Repeated measurements of the same variables over waves of data collection were also identified. We identified 21 categories of pain variables, which were subsequently grouped into themes: pain characteristics, extended pain characteristics and causes, treatment for pain, pain interference and pain-related to specific events. Pain and pain-related data have been collected from G1 participants, G0 mothers, and G0 partners, although there are fewer data for the partners. There were some repeated measurements, most commonly, of pain location. As is typical with longitudinal birth cohort studies, maternal proxy-reports were used during participants' younger years and self-reports were utilised from adolescence onwards. Researchers interested in studying pain can feasibly do so in two generations of a regional UK population who have been followed up over 30 years. ALSPAC can be used to study pain from the early years through to young adulthood and in mothers from the perinatal period onwards.

The feasibility of a Swiss complex interprofessional intervention to improve the management of procedural pain in neonates in the Finnish context: A qualitative study.

To evaluate the feasibility of the Swiss complex interprofessional intervention, NEODOL© (NEOnato DOLore), for improving the management of procedural pain in neonates in the Finnish context. Interprofessional collaboration is important for all professionals involved in the care of neonates and for neonates' parents, to understand the appropriate use of non-pharmacological and/or pharmacological methods for each pain situation and how to assess pain in real-life situations. Appropriate methods of pain relief for neonates should be preferred as they protect the development of the neonate's brain. A descriptive qualitative design. Data were collected through semi-structured focus group discussions following the Medical Research Council's framework for evaluation of complex interventions, in this case NEODOL© which aims to improve the procedural pain management of neonates. A purposive sample (n = 13) included eleven professionals representing various professions within Finnish Neonatal Intensive Care Units and two parents of infants who have received care in a Neonatal Intensive Care Unit. Data were analysed using inductive content analysis, and the results were reported in accordance with the COREQ guidelines. Professionals' and parents' evaluations suggest that NEODOL© is feasible, because it is consistent and addresses a current need. They assessed its overall content to be relevant and accessible, and its components to be internally coherent. However, they emphasise the need for further evaluation and refinement of the intervention to achieve the desired outcomes and cost-effectiveness. While NEODOL© is considered feasible, it requires further evaluation and refinement in the local context of each hospital before implementation.

Implantation of Reverse Shoulder Endoprothesis Using Navigation.

The implantation of a reverse shoulder arthroplasty (RSA) is a proven method for pain relief and improvement in shoulder function. Results vary, depending on the patient's age, the severity of the disease, and the experience of the surgeon. Indications for RSA are diverse, ranging from rotator cuff arthropathy to fractures. Recent studies show improved survival rates and reduced complications after primary implantation. Preoperative planning using 3D-CT or MRI is considered to be the gold standard. Patient-specific instruments (PSI) have been introduced, but are associated with costs and waiting times. Navigation with augmented reality (AR) provides a more efficient alternative. The intraoperative transfer of the plan to the patient is carried out via AR glasses, allowing real-time information without having to divert the surgeon's attention from the surgical site. This optimises the workflow and potentially yields more precise implantation results. In summary, the combination of 3D planning, navigation, and AR offers a promising method for precise and efficient RSA-implantations. Nevertheless, long-term results and functional scores are not yet available.

Patient satisfaction in the use of non-pharmacological therapies in the management of postoperative pain: a study in a tertiary hospital, Ghana

ABSTRACT Background: Non-pharmacological therapies are complementary to pharmacological therapies for managing disease symptoms, including pain, and can be integrated into a self-management program, enhancing patient independence and autonomy. It has been discovered that therapies that are non-pharmacological for pain relief are effective with minimal side effects. This study, therefore, seeks to determine how frequently non-pharmacological methods (NPMs) are used in the management of postoperative pain (POP) and the influence of these NPMs on patient satisfaction. Methods: This study had a descriptive cross-sectional design. A quantitative approach was used with a structured questionnaire based on the International Pain Outcome Questionnaire (IPO-Q) to obtain responses from patients from October 2019 to December 2019. Results: The majority of the patients, 52.2%, responded using some form of (NPM) for pain relief. The most widely used non-pharmacological method of pain relief was mobilization, representing 79.2%. The male participants were observed to use more NPMs for pain relief. Most patients (51.4%) who used NPMs for pain relief reported that their pain was not relieved. A majority (90.6%) of the participants desired more pain treatment. The type of surgery the patients underwent had a statistically significant negative correlation with using NPMs for pain relief. A higher percentage (71%) of participants were highly satisfied with their overall pain treatment. Conclusion: Pain is subjective, and it would be appropriate if patients were allowed to describe the location and intensity of their pain and choose their preferred NPMs which would be of help.

Effective Epidural Analgesia during Labor: A Feasible Method to Decrease Unnecessary Cesarean Deliveries in Thailand

Thailand has reported a high rate of cesarean delivery (45%–55%), prompting global concern about an increase in cesarean delivery rates. Fear of labor pains is one of the most common reasons pregnant women opt for cesarean delivery. Labor pain is associated with cervix dilation and fetal descent into the birth canal, which is exacerbated by ischemic pain caused by uterine contraction. Modern medical and non-medical techniques have demonstrated efficacy in reducing pain and ensuring safety during labor and delivery. Neuraxial labor analgesia is a highly effective medical pain relief method but has no effect on the rate of cesarean or assisted vaginal delivery. Medication administration for pain relief during labor, using a combination of a local anesthetic and an opioid, was observed to be transmitted across the placenta to the fetus, but had no significant effects on fetal outcomes in mothers who chose epidural analgesia. There are several techniques for administering neuraxial labor analgesia that can be customized for each pregnant woman. To achieve the most wonderful feasible labor and delivery experience, effective epidural labor analgesia is a crucial technique for reducing anxiety and suffering about labor pain. It is safe, widely used world-wide, and effective. Implementing a policy to increase public and medical providers awareness and acceptance of labor pain relief, as well as establishing a safe obstetric anesthesia service provided by obstetric anesthesiologists, could improve maternal and neonatal safety while significantly lowering the rate of unnecessary cesarean deliveries.

Evaluating the Effectiveness of Transcutaneous Electrical Nerve Stimulation for Various Outcomes in Emergency Department Settings: A Systematic Review and Meta-Analysis.

Pain is a prevalent complaint in emergency departments (EDs) worldwide. Traditional pharmacological methods for pain relief, such as opioids and non-steroidal anti-inflammatory drugs (NSAIDs), have notable side effects and risks. Transcutaneous electrical nerve stimulation (TENS) is a non-pharmacological alternative that has shown promise in various clinical settings. This systematic review and meta-analysis aimed to evaluate the effectiveness of TENS for pain management and other outcomes in ED settings. This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive search was conducted across six major databases: PubMed, Web of Science (WOS), Scopus, and Cochrane Central Register of Controlled Trials (CENTRAL), from inception until June 25, 2024. Randomized clinical trials involving the use of TENS in ED settings were included. Data extraction and quality assessment were performed independently by two reviewers, with conflicts resolved by a third reviewer. The search yielded 3,569 papers, of which 2,889 were screened after removing duplicates. Thirteen full-text articles were reviewed, and seven studies met the inclusion criteria for qualitative synthesis, with five of these suitable for meta-analysis. The studies demonstrated that TENS significantly reduced pain, heart rate, and the requirement for rescue medication in some cases, while also improving patient satisfaction and overall well-being. However, no significant changes were observed in blood pressure. The quality of the included studies varied, with some failing to meet the criteria for blinding and intention-to-treat analysis. TENS is an effective non-pharmacological intervention for pain management in ED settings, with additional benefits such as reduced heart rate and increased patient satisfaction. Further high-quality randomized controlled trials are necessary to confirm these findings and better understand the potential of TENS in acute care environments.

Empowering Adolescents: Exploring the Relationship between Self-Esteem and Test Anxiety

Background: Test anxiety is a major cause of student non-performance, despite adequate preparation. This paper is part of a multi-centric youth behavior study project done in 2022 by the Association of Adolescent and Child Care in India (AACCI). Aims: to study self-esteem and test anxiety in school children. Methods: The tools used were RSES- Rosenburg Self-esteem Score (scores &gt;25 are considered high self-esteem and FTAS- Freidben Test Anxiety Scale (scores &gt; 7 are considered significant). Sample: 242 students (10-18 years) studying in a coaching class in Aurangabad (males 53.31%, females 46.69%). Validity &amp; reliability: The RSES - Guttman scale coefficient of reproducibility is 0.92, indicating excellent internal consistency. Test-retest reliability over 2 weeks reveals correlations of 0.85 and 0.88. FTAS- the internal consistency (Cronbach’s alpha) of the total and the three sub-scales of the FTA (range: .81-.91validity, 0.82 (girls) and 0.84 (boys). It has also been shown to be significantly correlated with peer evaluations of the degree to which test-related stress is experienced (Total: 0.54; Fear of Social Derogation: 0.52; Cognitive Obstruction: 0.64; and Tenseness: 0.78. Ethical issues: This project has been cleared by the AACCI IEC. Parental permission and assent of students were taken. Statistical analysis was done using t-test/ANOVA by GNU PSPP. Results: Analysis of our data showed that this sample had significant mean test anxiety scores: total FTAS (9.19±5.37). SD-Social Derogation (3.84±2.61), CO-Cognitive Obstruction (2.46±2.17), and T-Tenseness (2.88±1.95). Females showed higher scores - total FTAS (10.23±5.10) and SD (4.40±2.54). A strong correlation was found between FTAS score and SD factor across all ages with the strongest positive correlation coefficient for early adolescent female students r (24) =.92, p&lt;.001. Conclusion: Females had higher test anxiety scores, and lower self-esteem scores and will need specific intervention. Being judged by marks affects the self-esteem of adolescents. SD factor was significant across ages in this sample. AACCI conducts awareness programs for parents and teachers to reduce social pressure on children given high SD scores. We also conduct intervention programs for improving CO scores by instilling good study skills and habits and relaxation and stress relief methods to reduce T scores in the context of test anxiety.

Prevalence of use of nonpharmacological methods of pain relief among patients following onco surgeries – A prospective, observational cohort study from a single center

Abstract Background and Aims: For the aggressive treatment of postoperative pain, nonpharmacological methods (NPMs) are gaining importance complementary to routine multimodal pain management. The primary aim of the study was to assess the incidence of use of NPMs in our hospital. Secondary objectives were to correlate the pain scores, patient satisfaction, and percentage of time the patient was in severe pain within 72 h postsurgery with the use of NPMs when in pain/not in pain. The effect of NPMs on the physical and emotional outcome of patients as per the American Pain Society Patient Outcome Questionnaire (APS-POQ) was also assessed. Material and Methods: After obtaining approval from the institutional ethics committee (IEC), the trial was registered with the Clinical Trials Registry of India (CTRI). Informed consent was obtained from adult patients on the third postoperative day of elective surgeries. Their responses to the APS-POQ and to a few additional questions about their beliefs on the use of NPM were recorded. Results: Only one-fourth of the total study population were using NPMs for pain management in the hospital. After propensity matching for surgery and postoperative analgesia, two groups were made: one using NPM for pain relief (n = 49) and the other not using NPM (n = 98). There was no significant difference among the satisfaction score (P = 0.31), least pain score (P = 0.68), and worst pain score (P = 0.43) within 72 h postoperatively in either of the groups. Emotional and physical outcomes as per the APS-POQ were similar in both the groups. Conclusion: NPMs are rarely practiced and used during postoperative pain in our hospital. No difference in pain scores, patient satisfaction, and emotional and physical outcomes of the APS-POQ was seen in the group that indulged in NPMs.

Upright Versus Recumbent Position in the Second Stage of Labor for Women With Epidural Analgesia: A Randomized Clinical Trial

Epidural analgesia (EA) is an effective and common method of pain relief during labor. However, EA may also have some adverse effects like prolonged labor, increased risk of operative delivery, and some unwanted complications. It's unclear how maternal position affects the outcomes of natural birth with EA. This study aimed to compare mode of delivery and maternal and neonatal outcomes between recumbent and upright positions in nulliparous women with EA. This randomized clinical trial involved 540 women who received EA at cervical dilatation of 4 to 6 cm. During the second stage of labor, they were instructed to adopt upright or recumbent position. The main outcome was the mode of delivery. The secondary outcomes included duration of labor, pain intensity, the Apgar score, and other maternal and neonatal complications. Finally, 528 women were included in the final analysis. The upright group had a higher rate of cesarean section than the recumbent group. The duration of the labor stages did not differ between the groups. The pain intensity in the second stage was higher in the upright position. The Apgar score at 1 and 5 minutes was higher in the recumbent group. There was no difference in terms of other outcomes between the groups. Recumbent positions are beneficial in the case of rate of cesarean, mother’s pain, and Apgar score in women with EA. So, adopting a recumbent position during the second stage of labor may be preferable for women with EA.

A narrative review of anxiety regulation in PhD students based on Green model.

To gain a better understanding of the factors that contribute to anxiety among PhD students and the reasons for poor regulation in the current situation, this paper analyses the existing literature on anxiety among PhD students using Green's model. It also compares and evaluates various methods of regulating anxiety. The literature review to extract information on the causes and levels of anxiety, methods and outcomes of anxiety intervention and regulation, and to make comparisons. The study reveals that the phenomenon of PhD students' anxiety has intensified globally in recent years, especially after the end of the epidemic. PhD students experience anxiety due to research pressure, economic pressure, future development, and interpersonal pressure. The main influencing factors are currently the relationship with the supervisor, development prospects, social support, and peer comparison. Among the stress relief methods, the regulation of self-relaxation was found to have better effects on mild anxiety, such as positive thinking, meditation, yoga and physical exercise can be helpful for emotion release then help focus on problem solved. Whereas severe anxiety may require institutional and pharmacological support, also including using psychological therapy such as behavioral cognitive therapy and systematic desensitization methods. For university, competence to provide course-assisted guidance, such as writing groups, peer support, and time management, is also important. Academic communities should pay attention to the guidance on academic fairness. However, PhD students are often unaware of the resources available to them for coping with stress and may not take the initiative to seek psychological counseling or institutional assistance. Therefore, PhD students should receive support from various sources, be guided to express their thoughts, and receive additional education and academic assistance to manage stress. This will enhance their confidence and aid in improving their scientific research.

1888~1889년 자인현감 오횡묵의 지방통치와 기민구제 -『慈仁叢瑣錄』을 중심으로-

1888~1889년 자인현감 오횡묵의 지방통치와 기민구제 -『慈仁叢瑣錄』을 중심으로-

Effectiveness of facilitated tucking on reducing pain during heel stick in neonates: a randomized controlled experimental study.

Pain in neonates is associated with adverse neurodevelopmental outcomes in the later days of life. Facilitated tucking is a nonpharmacological method of pain relief. The study aims to compare the effect of facilitated tucking in pain reduction in neonates. This was a randomized controlled experimental study conducted in the neonatal ward of a tertiary care center. There were 25 neonates randomized each in the experimental and control groups (total of 50), based on computer-generated random tables. The experimental group was placed in a facilitated tucking position during heel stick, while the control group was kept in the usual position, as done routinely. A self-structured questionnaire and Neonatal Infant Pain Scale were used. The main outcome measures were the mean Neonatal Infant Pain Scale score, and change in preprocedure and postprocedure heart rate and oxygen saturation in the two groups. Ethical clearance and informed written consent were sought. Neonates in the experimental group had significantly lesser pain (less Neonatal Infant Pain Scale score) than the neonates in the control group (P<0.001). There was also a significant increment in the mean heart rate and a decrease in the oxygen saturation after the procedure in the control group, indicating significantly more pain perception (P<0.001) in the control group. Facilitated tucking was found to be effective in reducing the pain during heel stick procedures in neonates.

Machine learning based severity classification of obstructive sleep apnea patients using awake EEG

Obstructive sleep apnea (OSA) is one of the most widespread breathing-based sleep disorders. Previous studies reported daytime sleepiness, mental fatigue, and cognitive decline in patients with OSA. The diagnosis of OSA is done with laborious overnight polysomnography (PSG) recording. This study aims to classify the severity of OSA patients according to the Apnea-Hypopnea Index (AHI) into mild and moderate to-serve groups (AHI ≥ 15) without using recorded signals during sleep, non-PSG signals and investigate the relevant features. For this purpose, 25 OSA patients participated in 3-minute eyes closed resting state EEG session on the following morning of overnight PSG recording. Time, spectral domain, and nonlinear features were extracted from the delta, theta, and alpha subbands’ of EEG signals. Several machine learning algorithms were used to classify patients’ severity. To investigate optimal feature combinations features were grouped according to their types (Time domain/spectral domain and nonlinear), their electrodes (frontal/central/parietal/occipital), and their subbands (delta/theta/alpha). Also, the Relief method was applied to select the most relevant features. A 5-fold cross validation method was used to generalize the model behaviour. Optimal feature combinations were selected according to classifiers' performances that were evaluated by accuracy, sensitivity, specificity, and area under curve (AUC) parameters when feature sets were used as input. The 15 selected features by the Relief method showed the best performances in the K-Nearest Neighbours (K = 5) classifier [accuracy: 93.33 % ± 5.27 %; sensitivity: 92.30 % ± 4.97 %; specificity: 94.14 % ± 4.24 %; AUC:0.98]. The findings establish that awake resting state EEG records might be used as a faster tool to use OSA severity level.

'Giving birth on a beach': Women's experiences of using virtual reality in labour.

Birth is a normal physiological process, and many women want a natural birth. Women use a range of non-pharmacological pain relief methods to reduce labour pain intensity, to help manage labour pain and to induce relaxation. The purpose of this study was to explore the experiences of women using Virtual Reality as a non-pharmacological method of pain relief in labour. Virtual Reality has been shown to be an effective distraction technique in other acute pain settings which also reduces anxiety. This study conducted qualitative in-depth interviews postnatally with women who used Virtual Reality in labour. Thematic analysis was used to analyse the qualitative data. Nineteen women used Virtual Reality in labour. Results from interviews with nineteen women in the postnatal period identified three main themes: impact of virtual reality on experience of labour, managing the pain of labour and challenges of using virtual reality in labour. This study identified that Virtual Reality was effective as a relaxation technique and helped in pain management by the use of self-efficacy techniques. Women in this study also identified preferred virtual environments specifically to use during labour and birth. This study provides a unique and original contribution to the field of Virtual Reality in labour and birth. It also identifies Virtual Reality as an acceptable and positive experience in the management of anxiety and labour pain.