Mesotherapy Research Articles

Extracorporeal shockwave therapy versus musculoskeletal mesotherapy for Achilles tendinopathy in athlete

BackgroundAchilles tendinopathy (AT) is considered the commonest tendon pathology, occurring mainly in athletes. Different conservative treatment options have been introduced but with short-term effects; however, extracorporeal shockwave therapy (ESWT) and mesotherapy (MT) injections were claimed to provide longer effects and could be used in cases failure of response to conservative treatments.The objective of our prospective 12-week study was to compare the effect of ESWT and MT on chronic Achilles tendinopathy in athletes by both clinical and ultrasonographical assessment.ResultsForty patients with chronic AT diagnosed clinically and with high-resolution ultrasound (US) randomly allocated in two groups first received weekly ESWT session, and the other group underwent weekly MT sessions for 4 consecutive weeks. Both groups improved during the treatment and follow-up period. The mean visual analogue score (VAS) decreased in both the ESWT group and the MT group. Mean American Orthopedic Foot and Ankle Society (AOFAS) hindfoot score and VAS scores were not significantly different between ESWT and MT groups at the 4th and the 12th week of follow-up. However, US assessment significantly improved after 12 weeks in the ESWT group (as regards tendon thickness, calcifications, and Doppler signal), and for the mesotherapy group, there was the only improvement of tendon thickness.ConclusionESWT showed improvement of pain and inflammation and calcifications of AT than MT injections, which was documented by US improved findings at week 12 follow up.

Erratum to "Therapeutic Effectiveness and Safety of Mesotherapy in Patients with Osteoarthritis of the Knee".

[This corrects the article DOI: 10.1155/2018/6513049.].

Effect of dimethylaminoethano and compound amino acid on collagens I and III mRNA expression in the skin of D-galactose induced aging model in rats

Objective To study the effect of dimethylaminoethano (DMAE) and compound amino acid injection (AA) by mesotherapy on collagen Ⅰ and collagen Ⅲ mRNA expression levels of D-galactose-induced chemical skin aging rats.Methods 80 rats were randomly divided into individual experimental group.At 18 days after D-gal induction,rats of aging treatment groups were treated with intradermal microinjection of 0.2％ DMAE+AA,0.1％ DMAE+AA,0.2％ DMAE,0.1％ DMAE,AA,and saline,respectively,once a week for 4 weeks.At 42 days after treatment,the skin wounds were harvested.HE,PCNA,hydroxyproline and collagen Ⅰ and collagen Ⅲ mRNA expression levels of every group skins were detected.Results Dermal thickness,hydroxyproline content and collagen type Ⅰ and Ⅲ mRNA expression levels of 0.1％ DMAE+ AA and 0.2 ％ DMAE+ AA groups were significantly improved (P＜0.05),but PCNA expression of sham control group was significantly higher than all of aging groups (P＞0.05).Conclusions Local co-injection of DMAE and compound AA directly into targeted tissue under mesotherapy has marked anti-aging effects on D-galactose induced skin aging model of rat by increasing the dermal thickness,collagen content and acceleration of collagen synthesis. Key words: Mesotherapy; Dimethylaminoethanol; Compound amino acid ; Anti-aging; Ⅰ and Ⅲ collagen; PCNA; D-galactose

Mesotherapy granulomas with L-carnitine

Mesotherapy granulomas with L-carnitine

Mesotherapy: What is new?

Mesotherapy: What is new?

The influence of procaine electrophoresis and mesotherapy on the characteristics of biological age

The assessment of the biological age is needed to estimate the level of health and the efficacy of measures being undertaken to slow down the ageing processes and prolong the active life of the patients. Earlier studies have demonstrated the improvement of both physical health and psychic status of the elderly patients following intravenous administration of procaine. The objective of the present work was to evaluate effect of various methods of administration of a 2% procaine solution on the biological age. A total of 95 subjects at the age between 30 and 75 years were enrolled in the study. The procaine solutions were applied to the collar region. The patients of group 1 were treated with 2% procaine electrophoresis, those in group 2 with procaine galvanization with the same parameters. Mesotherapy using the 2% procaine solution was given to the patients of group 3. It was substituted by placebo (0.9% physiological solution) in the patients of group 4 (controls). The study revealed the most significant decrease of the biological age (calculated as described by L. M. Belozerova) in the patients treated with procaine electrophoresis (91% improvement). The mesotherapeutic administration of procaine also produced the beneficial effect (59% improvement). Neither procaine galvanization nor placebo mesotherapy caused any significant change of the variables characterizing the biological age.

Hair Mesotherapy

Hair Mesotherapy

Effect of the mesotherapy with the use of Ekyced P.I. cream on age-related changes in skin

Sixty women (average age: 44.8+1,1) underwent examination with the use of Skin XP Pro software, laser Doppler flowmetry and CAH psychological test for assessment of the effect of mesotherapy (MT) with the use of Ekyced P.I. cream on age-related changes in facial skin. A course of MT with the use of Ekyced P.I. cream, which was applied prior to and after mesotherapy, as well as Ubichinon Compositum and Placenta Compositum resulted in an evident reduction in the intensity of wrinkles, increase in the level of elasticity and hydration as well as normalization of the level of skin oiliness. The use of Ekyced P.I. regenerating cream resulted in a considerable reduction in the frequency of development of MT side effects such as edemas, erythema, purpura. Mesotherapy with the use of Ekyced P.I. in women older than 45 was accompanied by a more evident increase in the level of skin hydration and elasticity than in women younger than 45.

Combined application of electric myo-stimulation and meso-therapy for the correction of age-related changes of the facial skin

The objective of the present study was to evaluate effects of mesotherapy (MT) and electrostimulation (EMS) on age-related changes of the facial skin. The secondary objective was to identify factors influencing the therapeutic efficiency of these methods. The study included 60 women aged from 30 to 59 years. All the patients were examined prior to the onset and in the end (after one month) of the corrective treatment. Facial skin conditions were assessed using a Skin XP Pro system and skin microcirculation by laser Doppler flowmetry (LDF). The psychological status of the patients was evaluated with the help of the Well-being-Activity-Mood test. After the primary examination, the participants of the study were randomly divided into two groups. Group 1 (n=30) included women treated by MT and EMS, the control group 2 (n=30) was comprised of the patients who did not receive the above treatment. The results of the study indicate that combine MT + EMS therapy significantly improves the state of facial skin, decreases its pigmentation, reduces the number and depth of wrinkles, enhances skin moisture, improves its elasticity and decreases porosity. Dynamics of these parameters and overall effect of correction were shown to correlate with the severity of skin changes before the treatment. Age-related changes in the facial skin were especially well-apparent in women with the lowered activity level and impaired mood. Characteristics of mood in the course of therapeutic correction correlated with dynamics of skin smoothness and elasticity.

An evaluation of mesotherapy solutions for inducing lipolysis and treating cellulite

An evaluation of mesotherapy solutions for inducing lipolysis and treating cellulite

Mycobacterial Infections After Mesotherapy

Mesotherapy involves the injection of various substances into the tissue beneath the skin to sculpt body contours by lysing subcutaneous fat. Cutaneous

Mesotherapy and Lipolysis

Mesotherapy and Lipolysis

Lipodissolve Mesotherapy Is Gaining Popularity

Lipodissolve Mesotherapy Is Gaining Popularity

Mesotherapy for Skin Rejuvenation

Mesotherapy is a technique that delivers vitamins, herbal extracts, and other ingredients to the mesodermal layer of the skin. Mesotherapy using multivitamin injections as an anti-aging skin treatment has been touted and used by many medical and nonmedical practitioners, despite the existence of only anecdotal reports of its effectiveness. In a prospective study, 10 patients underwent four sessions of facial mesotherapy using …

Sporotrichosis Following Mesotherapy for Arthrosis

Sporotrichosis Following Mesotherapy for Arthrosis

Data Validate Some Lipolysis, but Not Mesotherapy

Data Validate Some Lipolysis, but Not Mesotherapy