The unsaturated zone profoundly affects groundwater (GW) flow induced by pumping and injection due to the capillary forces. However, current radial basis function (RBF) numerical models for GW pumping and injection mostly ignore the unsaturated zone. To bridge this gap, we developed a new three-dimensional weak strong form RBF model in this study, called CCHE3D-GW-RBF. Flow processes were modelled by the mixed-form Richards equation which was iteratively solved by the modified Picard iteration. Soil-water characteristic curves were represented by the widely applicable formulas, the van Genuchten (1980) model. Differential operators were approximated by the localized Gaussian RBF, and the weighted singular value decomposition method was used to construct stable bases. The injection/pumping wells and the flux boundaries were handled by the weak formulation using Meshless Local Petrov Galerkin method, and the strong-form equation using the collocation RBF method was enforced on the other points. Good agreement was found between the simulation results from our numerical model and the well-accepted solutions in all three verification cases, demonstrating the accuracy and applicability of this model. In addition, a smaller RBF shape parameter was found to produce a more accurate modelling resulting, indicating the necessity of implementing stable bases for RBF models.