Mesh-type Reference Computational Phantoms Research Articles

Comparative study of radiation ionizing on the MRCP-AM phantom before and after using the Bi2O3[formula omitted]AlF3[formula omitted]CaO[formula omitted]B2O3 shielding glass by PHITS Monte Carlo simulation

The estimation of radiation hazards to the human body before and after the use of shielding glass is the next level of research on its radiation shielding properties. In this work, the glass compositions of the xBi2O3−20AlF3−20CaO− (60-x)B2O3 (where 0≤x≤40 mol%) were prepared by the melt-quenching method. The adult male mesh-type reference computational phantoms (MRCP-AM) were used to represent the whole human body, including the shape, chemical composition, and densities of every organ. The absorbed dose and effective dose rate on the phantom before and after using the shielding glass (thickness 1.0 cm) were estimated by PHITS Monte Carlo simulation. The mono-energetic photon of 0.662 MeV was irradiated with an anterior-posterior (AP) direction. In addition, the physical properties and gamma-ray shielding properties of the glasses, including the density (ρ), molar volume (Vm), mass attenuation coefficient (μm), half-value layer (HVL), Zeff, and Neff, were investigated by PHITS and XCOM in an energy range of 0.015 MeV–15 MeV, as well as comparison with experimental methods at different energy (133Ba, 137Cs, and 60Co sources). The results found that the addition of the Bi2O3 content into the glass structure affects the increase of the ρ, Vm, μm, Zeff, and Neff but the decrease of the HVL. In addition, the comparative study of radiation dose on the MRCP-AM phantom before and after using the shielding glass by PHITS Monte Carlo simulation demonstrated that the 40Bi2O3 glass sample can reduce damage to the brain, liver, left lung, right lung, prostate, skin, and thyroid, which are equal to 30.34%, 28.93%, 29.33%, 29.70%, 21.15%, 25.72%, and 21.99%, respectively, when compared with no shielding materials. The effective dose rate in MRCP-AM with shielding glass revealed significantly less damage than without shielding glass.

Pediatric phantom library constructed from ICRP mesh-type reference computational phantoms (MRCPs)

International Commission on Radiological Protection (ICRP) recently developed the adult and pediatric mesh-type reference computational phantoms (MRCPs) in high-quality/fidelity mesh format, featuring high deformability into various body sizes and poses. Utilizing this feature, the adult MRCPs-based body-size-dependent phantom library was developed for individualized dosimetry. To complete the full phantom library set, the present study produced the pediatric-MRCPs-based body-size-dependent pediatric phantom library. The library comprises a total of 637 phantoms (356 males and 281 females) with varying standing heights and body weights, covering a wide range of body sizes (i.e., including from 1st to 99th percentile height and weight values) for infants, children, and adolescents, offering a realistic representation of body shapes by reflecting ten secondary anthropometric parameters. The phantoms were automatically constructed utilizing automatic deformation program. The dosimetric impact of the library was investigated by calculating organ doses for external exposures to broad parallel photon beams in anterior-posterior direction. Compared with the values of the pediatric MRCPs, significant differences were observed at energies <0.05 MeV, showing larger values for underweight phantom and smaller values for obese phantom. The results highlight the importance of using the pediatric phantom library for accurate dose estimates of individual children with various body sizes.

Development of Respiratory Tract Organs for ICRP Pediatric Mesh-type Reference Computational Phantoms.

As part of the activities of the International Commission on Radiological Protection (ICRP) Task Group 103, the present study developed a new set of respiratory tract organs consisting of the extrathoracic, bronchial, bronchiolar, and alveolar-interstitial regions for newborn, 1-, 5-, 10-, and 15-y-old males and females for use in pediatric mesh-type reference computational phantoms. The developed respiratory tract organs, while preserving the original topologies of those of the pediatric voxel-type reference computational phantoms of ICRP Publication 143, have improved anatomy and detailed structure and also include μm-thick target and source regions prescribed in ICRP Publication 66. The dosimetric impact of the developed respiratory tract organs was investigated by calculating the specific absorbed fraction for internal electron exposures, which were then compared with the ICRP Task Group 96 values. The results showed that except for the alveolar-interstitial region as a source region, the pediatric mesh phantoms showed larger specific absorbed fractions than the Task Group 96 values. The maximum difference was a factor of ~3.5 for the extrathoracic-2 basal cell and surface as target and source regions, respectively. These results reflect the differences in the target masses and geometry caused by the anatomical enhancement of the pediatric mesh phantoms. For the alveolar-interstitial region as a source region, the pediatric mesh phantoms showed larger values for low energy ranges and lower values with increasing energies, owing to the differences in the size and shape of the alveolar-interstitial region.

Dose estimation for cone-beam computed tomography in image-guided radiation therapy for pelvic cancer using adult mesh-type reference computational phantoms

The use of cone-beam computed tomography (CBCT) is expanding owing to its installation in linear accelerators for radiation therapy, and the imaging dose induced by this system has become the center of attention. Here, the dose to patients caused by the CBCT imager was investigated. Organ doses and effective doses for male and female mesh-type reference computational phantoms (MRCPs) and pelvis CBCT mode, routinely used for pelvic irradiation, were estimated using the Particle and Heavy Ion Transport Code System. The simulation results were confirmed based on the point-dose measurements. The estimated organ doses for male MRCPs with/without raised arms and for female MRCPs with/without raised arms were 0.00286-35.6mGy, 0.00286-35.1mGy, 0.00933-39.5mGy, and 0.00931-39.0mGy, respectively. The anticipated effective doses for male MRCPs with/without raised arms and female MRCPs with/without raised arms irradiated by pelvis CBCT mode were 4.25mSv, 4.16mSv, 7.66mSv, and 7.48mSv, respectively. The results of this study will be useful for patients who undergo image-guided radiotherapy with CBCT. However, because this study only covered one type of cancer with one type of imager, and image quality was not considered, more studies should be conducted to estimate the radiation dose from imaging devices in radiation therapy.

An Investigation of Body Size Impact on Organ Doses for Neutron External Exposures Using the MRCP-based Phantom Library.

In a recent study, a comprehensive library composed of 212 phantoms with different body sizes was established by deforming the adult male and female mesh-type reference computational phantoms (MRCPs) of ICRP Publication 145 and the next-generation ICRP reference phantoms over the current voxel-type reference phantoms of ICRP Publication 110. In this study, as an application of the MRCP-based phantom library, we investigated dosimetric impacts due to the different body sizes for neutron external exposures. A comprehensive dataset of organ/tissue dose coefficients (DCs) for idealized external neutron beams with four phantoms for each sex representatively selected from the phantom library were produced by performing Monte Carlo simulations using the Geant4 code. The body size-dependent DCs produced in this study were systematically analyzed, observing that the variation of the body weights overall played a more important role in organ/tissue dose calculations than the variation of the body heights. We also observed that the reference body-size DCs based on the MRCPs indeed significantly under- or overestimated the DCs produced using the phantoms, especially for those much heavier (male: 175 cm and 140 kg; female: 165 cm and 140 kg) than the reference body sizes (male: 176 cm and 73 kg; female: 163 cm and 60 kg) by up to 1.6 or 3.3 times, respectively. We believe that the use of the body size-dependent DCs, together with the reference body-size DCs, should be beneficial for more reliable organ/tissue dose estimates of individuals considering their body sizes rather than the most common conventional approach, i.e., the sole use of the reference body size DCs.

Incorporation of micro-CT-based detailed bone models into ICRP adult mesh-type reference computational phantoms

Objective. The red bone marrow (RBM) and bone endosteum (BE), which are required for effective dose calculation, are macroscopically modeled in the reference phantoms of the international commission on radiological protection (ICRP) due to their microscopic and complex histology. In the present study, the detailed bone models were developed to simplify the dose calculation process for skeletal dosimetry. Approach. The detailed bone models were developed based on the bone models developed at the University of Florida. A new method was used to update the definition of BE region by storing the BE location indices using virtual sub-voxels. The detailed bone models were then installed in the spongiosa regions of the ICRP mesh-type reference computational phantoms (MRCPs) via the parallel geometry feature of the Geant4 code. Main results. Comparing the results between the detailed-bone-installed MRCPs and the original MRCPs with the absorbed dose to spongiosa and fluence-to-dose response function (DRF)-based methods, the DRF-based method showed much smaller but still significant differences. Compared with the values given in ICRP Publications 116 and 133, the differences were very large (i.e. several orders of magnitudes), due mainly to the anatomical improvement of the skeletal system in the MRCPs; that is, spongiosa and medullary cavity are fully enclosed by cortical bone in the MRCPs but not in the ICRP-110 phantoms. Significance. The detailed bone models enable the direct calculation of the absorbed doses to the RBM and BE, simplifying the dose calculation process and potentially improving the consistency and accuracy of skeletal dosimetry.

Applications of a patient-specific whole-body CT-mesh hybrid computational phantom in second cancer risk prediction

Objective. CT-mesh hybrid phantoms (or ‘hybrid(s)’) made from integrated patient CT data and mesh-type reference computational phantoms (MRCPs) can be beneficial for patient-specific whole-body dose evaluation, but this benefit has yet to be evaluated for second cancer risk prediction. The purpose of this study is to compare the hybrid’s ability to predict risk throughout the body with a patient-scaled MRCP against ground truth whole-body CTs (WBCTs). Approach. Head and neck active scanning proton treatment plans were created for and simulated on seven hybrids and the corresponding scaled MRCPs and WBCTs. Equivalent dose throughout the body was calculated and input into five second cancer risk models for both excess absolute and excess relative risk (EAR and ERR). The hybrid phantom was evaluated by comparing equivalent dose and risk predictions against the WBCT. Main results. The hybrid most frequently provides whole-body second cancer risk predictions which are closer to the ground truth when compared to a scaled MRCP alone. The performance of the hybrid relative to the scaled MRCP was consistent across ERR, EAR, and all risk models. For all in-field organs, where the hybrid shares the WBCT anatomy, the hybrid was better than or equal to the scaled MRCP for both equivalent dose and risk prediction. For out-of-field organs across all patients, the hybrid’s equivalent dose prediction was superior than the scaled MRCP in 48% of all comparisons, equivalent for 34%, and inferior for 18%. For risk assessment in the same organs, the hybrid’s prediction was superior than the scaled MRCP in 51.8% of all comparisons, equivalent in 28.6%, and inferior in 19.6%. Significance. Whole-body risk predictions from the CT-mesh hybrid have shown to be more accurate than those from a reference phantom alone. These hybrids could aid in risk-optimized treatment planning and individual risk assessment to minimize second cancer incidence.

Development of alimentary tract organs for ICRP pediatric mesh-type reference computational phantoms

In line with the activities of Task Group 103 under the International Commission on Radiological Protection (ICRP), the present study was conducted to develop a new set of alimentary tract organs consisting of the oral cavity, oesophagus, stomach, small intestine, and colon for the newborn, 1 year-old, 5 year-old, 10 year-old, and 15 year-old males and females for use in the pediatric mesh-type reference computational phantoms (MRCPs). The developed alimentary tract organs of the pediatric MRCPs, while nearly preserving the original topology and shape of those of the pediatric voxel-type reference computational phantoms (VRCPs) of ICRP Publication 143, present considerable anatomical improvement and include all micrometre-scale target and source regions as prescribed in ICRP Publication 100. To investigate the dosimetric impact of the developed alimentary tract organs, organ doses and specific absorbed fractions were computed for certain external exposures to photons and electrons and internal exposures to electrons, respectively, which were then compared with the values computed using the current ICRP models (i.e. pediatric VRCPs and ICRP-100 stylised models). The results showed that for external exposures to penetrating radiations (i.e. photons >0.04 MeV), there was generally good agreement between the compared values, within a 10% difference, except for the oral mucosa. For external exposures to weakly penetrating radiations (i.e. low-energy photons and electrons), there were significant differences, up to a factor of ∼8300, owing to the geometric difference caused by the anatomical enhancement in the MRCPs. For internal exposures of electrons, there were significant differences, the maximum of which reached a factor of ∼73 000. This was attributed not only to the geometric difference but also to the target mass difference caused by the different luminal content mass and organ shape.

New thyroid models for ICRP pediatric mesh-type reference computational phantoms

As part of the ICRP Task Group 103 project, we developed ten thyroid models for the pediatric mesh-type reference computational phantoms (MRCPs). The thyroid is not only a radiosensitive target organ needed for effective dose calculation but an important source region particularly for radioactive iodines. The thyroid models for the pediatric MRCPs were constructed by converting those of the pediatric voxel-type reference computational phantoms (VRCPs) in ICRP Publication 143 to a high-quality mesh format, faithfully maintaining their original topology. At the same time, we improved several anatomical parameters of the thyroid models for the pediatric MRCPs, including the mass, overlying tissue thickness, location, and isthmus dimensions. Absorbed doses to the thyroid for the pediatric MRCPs for photon external exposures were calculated and compared with those of the pediatric VRCPs, finding that the differences between the MRCPs and VRCPs were not significant except for very low energies (<0.03 MeV). Specific absorbed fractions (target ← thyroid) for photon internal exposures were also compared, where significant differences were frequently observed especially for the target organs/tissues close to the thyroid (e.g., a factor of ∼1.2–∼327 for the thymus as a target) due mainly to anatomical improvement of the MRCP thyroid models.

Dose estimation for cone-beam computed tomography in image-guided radiation therapy using mesh-type reference computational phantoms and assuming head and neck cancer

This study aimed to estimate the additional dose the cone-beam computed tomography (CBCT) system integrated into the Varian TrueBeam linear accelerator delivers to a patient with head and neck cancer using mesh-type International Commission on Radiological Protection reference computational phantoms. In the first part, for use as a benchmark for the accuracy of the Monte Carlo geometry of CBCT, Particle and Heavy Ion Transport code System (PHITS) calculations were confirmed against measured lateral and depth dose profiles using a computed tomography dose profiler. After obtaining good agreement, organ dose calculations were performed by PHITS using mesh-type reference computational phantom (MRCP) and irradiating the neck region; the effective dose was calculated utilising absorbed organ doses and tissue weighting factors for male and female MRCP. Substantially, it has been found that the effective doses for male and female MRCP are 0.81 and 1.06 mSv, respectively. As this study aimed to assess the imaging dose from the CBCT system used in image-guided radiation therapy, it is required to take into account this dose in terms of both the target organ and surrounding tissues. Although the absorbed organ dose values and effective dose values obtained for both MRCP males and females were small, attention should be paid to the additional dose resulting from CBCT. This study can create awareness on the importance of doses arising from imaging techniques, especially CBCT.

Physical dosimetric reconstruction of a case of large area back skin injury due to overexposure in an interventional procedure

To estimate the physical dose of skin and key organs in a case of overexposure during a cardiac interventional procedure. MethodsThe female patient aged 50 suffered from overexposure during cardiac interventional therapy in a hospital, Xinxiang city, Henan province, China in January 2020. The mesh-type phantom for the patient was constructed based on the adult mesh-type reference computational phantoms (MRCPs) released by the International Commission on Radiological Protection Publication 145 (ICRP145) and phantom deformation technology. Models of exposure scenario were constructed and simulated with particle and heavy ion transport code system (PHITS) according to exposure conditions. ResultsThe maximum absorbed dose of key organs/tissues under irradiation in posteroanterior (PA) and 30° left anterior oblique directions(LOA) was 632.4 and 305.6 ​mGy, respectively. The left lung, heart, and left mammary gland received a larger dose under both irradiation conditions. The ratio of the absorbed dose with and without shielding was calculated, and the relative difference in most organs was <1% between two directions. The iso-dose curve of the back skin revealed the distribution of the absorbed dose (0.1 −5.2 ​Gy). The dose estimate of key tissues/organs was higher than the conventional level, especially the local skin, up to 5.2 ​Gy. ConclusionsThe interventional procedure in this case resulted in a higher dose. Monte Carlo codes combined with the MRCPs can be employed to estimate physical dose to individuals in concrete irradiation scenarios.

Detailed tooth models for ICRP mesh-type reference computational phantoms

For use in electron paramagnetic resonance dosimetry with tooth enamel, in the present study, very detailed mesh-type tooth models composed of 198 individual tooth models (i.e. newborn: 20; 1 year: 28; 5 years: 48; 10 years: 38; 15 years: 32; and adult: 32) were developed for each sex. The developed tooth models were then implanted in the International Commission on Radiological Protection pediatric and adult mesh-type reference computational phantoms and used to calculate tooth enamel doses, by Monte Carlo simulations with Geant4, for external photon exposures in several idealized irradiation geometries. The calculated dose values were then compared to investigate the dependency of the enamel dose on the age and sex of the phantom and the sites of the teeth. The results of the present study generally show that, if the photon energy is low (i.e. <0.1 MeV), the enamel dose is significantly affected by the age and sex of the phantom and also the sites of the teeth used for dose calculation; the differences are frequently greater than a few times or even orders of magnitude. However, with a few exceptions, the enamel dose was hardly affected by these parameters for energies between 0.1 and 3 MeV. For energies >3 MeV, moderate differences were observed (i.e., up to a factor of two), due to the existence of dose build-up in the head of the phantom for high-energy photons. The calculated dose values were also compared with those of the previous studies where voxel and mathematical models were used to calculate the enamel doses. The results again show significant differences at low energies, e.g., up to ∼3500 times at 0.015 MeV, which are mainly due to the differences in the level of tooth-modeling detailedness.

Development of paediatric mesh-type reference computational phantom series of International Commission on Radiological Protection

Very recently, Task Group 103 of the International Commission on Radiological Protection (ICRP) completed the development of the paediatric mesh-type reference computational phantoms (MRCPs) comprising ten phantoms (newborn, one year-old, five year-old, ten year-old, and fifteen year-old males and females). The paediatric MRCPs address the limitations of ICRP Publication 143’s paediatric reference computational phantoms, which are in voxel format, stemming from the nature of the voxel geometry and the limited voxel resolutions. The paediatric MRCPs were constructed by converting the voxel-type reference phantoms to a high-quality mesh format with substantial enhancements in the detailed anatomy of the small and complex organs and tissues (e.g. bones, lymphatic nodes, and extra-thoracic region). Besides, the paediatric MRCPs were developed in consideration of the intra-organ blood contents and by modelling the micron-thick target and source regions of the skin, lens, urinary bladder, alimentary tract organs, and respiratory tract organs prescribed by the ICRP. For external idealised exposures, the paediatric MRCPs provide very similar effective dose coefficients (DCEs) to those from the ICRP-143 phantoms but significantly different values for weakly penetrating radiations (e.g. the difference of ∼20 000 times for 10 keV electron beams). This paper introduces the developed paediatric MRCPs with a brief explanation of the construction process. Then, it discusses their computational performance in Geant4, PHITS, and MCNP6 in terms of memory usage and computation speed and their impact on dose calculations by comparing their calculated values of DCEs for external exposures with those of the voxel-type reference phantoms.

Measurement uncertainty analysis of radiophotoluminescent glass dosimeter reader system based on GD-352M for estimation of protection quantity

At the Korea Institute of Radiological and Medical Sciences, physical human phantoms were developed to evaluate various radiation protection quantities, based on the mesh-type reference computational phantoms of the International Commission on Radiological Protection. The physical human phantoms were fabricated such that a radiophotoluminescent glass dosimeter (RPLGD) with a Tin filter, namely GD-352M, could be inserted into them. A Tin filter is used to eliminate the overestimated signals in low-energy photons below 100 keV. The measurement uncertainty of the RPLGD reader system based on GD-352M should be analyzed for obtaining reliable protection quantities before using it for practical applications. Generally, the measurement uncertainty of RPLGD systems without Tin filters is analyzed for quality assurance of radiotherapy units using a high-energy photon beam. However, in this study, the measurement uncertainty of GD-352M was analyzed for evaluating the protection quantities. The measurement uncertainty factors in the RPLGD include the reference irradiation, regression curve, reproducibility, uniformity, energy dependence, and angular dependence, as described by the International Organization for Standardization (ISO). These factors were calculated using the Guide to the Expression of Uncertainty in Measurement method, applying ISO/ASTM standards 51261(2013), 51707(2015), and SS-ISO 22127(2019). The measurement uncertainties of the RPLGD reader system with a coverage factor of k = 2 were calculated to be 9.26% from 0.005 to 1 Gy and 8.16% from 1 to 10 Gy. A blind test was conducted to validate the RPLGD reader system, which demonstrated that the readout doses included blind doses of 0.1, 1, 2, and 5 Gy. Overall, the En values were considered satisfactory.

Development of skeletal systems for ICRP pediatric mesh-type reference computational phantoms

In 2016, the International Commission on Radiological Protection (ICRP) launched Task Group 103 (TG 103) for the explicit purpose of developing a new generation of adult and pediatric reference computational phantoms, named ‘mesh-type reference computational phantoms (MRCPs)’, that can overcome the limitations of voxel-type reference computational phantoms (VRCPs) of ICRP Publications 110 and 143 due to their finite voxel resolutions and the nature of voxel geometry. After completing the development of the adult MRCPs, TG 103 has started the development of pediatric MRCPs comprising 10 phantoms (male and female versions of the reference newborn, 1-year-old, 5-year-old, 10-year-old, and 15-year-old). As part of the TG 103 project, within the present study, the skeletal systems, one of the most important and complex organ systems of the body, were developed for each phantom age and sex. The developed skeletal systems, while closely preserving the original bone topology of the pediatric VRCPs, present substantial improvements in the anatomy of complex and/or small bones. In order to investigate the dosimetric impact of the developed skeletons, the average absorbed doses and the specific absorbed fractions for radiosensitive skeletal tissues (i.e. active marrow and bone endosteum) were computed for some selected external and internal exposure cases, which were then compared with those calculated with the skeletons of pediatric VRCPs. The comparison result showed that the dose values of the pediatric MRCPs were generally similar to those of the pediatric VRCPs for highly penetrating radiations (e.g. photons >200 keV); however, for weakly penetrating radiations (e.g. photons ⩽200 keV and electrons), significant differences up to a factor of 140 were observed.

Development of detailed pediatric eye models for lens dose calculations

The International Commission on Radiological Protection (ICRP) recently reduced the dose limit for the eye lens for occupational exposure from 150 mSv yr−1 to 20 mSv yr−1, as averaged over defined periods of five years, with no annual dose in a single year exceeding 50 mSv, emphasizing the importance of the accurate estimation of lens dose. In the present study, for more accurate lens dosimetry, detailed eye models were developed for children and adolescents (newborns and 1, 5, 10, and 15 year olds), which were then incorporated into the pediatric mesh-type reference computational phantoms (MRCPs) and used to calculate lens dose coefficients (DCs) for photon and electron exposures. Finally, the calculated values were compared with those calculated with the adult MRCPs in order to determine the age dependence of the lens DCs. For photon exposures, the lens DCs of the pediatric MRCPs showed some sizable differences from those of the adult MRCPs at very low energies (10 and 15 keV), but the differences were all less than 35%, except for the posterior-anterior irradiation geometry, for which the lens dose is not of primary concern. For electron exposures, much larger differences were found. For the anterior-posterior (AP) and isotropic irradiation geometries, the largest differences between the lens DCs of the pediatric and adult phantoms were found in the energy range of 0.6–1 MeV, where the newborn lens DCs were larger by up to a factor of ∼5 than the adult. The lens DCs of the present study, which were calculated for the radiosensitive region of the lens, also were compared with those for the entire lens in the AP irradiation geometry. Our results showed that the DCs of the entire lens were similar to those of the radiosensitive region for 0.02–2 MeV photons and >2 MeV electrons, but that for the other energy ranges, significant differences were noticeable, i.e. 10%–40% for photons and up to a factor of ∼5 for electrons.

Dose conversion coefficients for neutron external exposures with five postures: walking, sitting, bending, kneeling, and squatting.

In a previous study, posture-dependent dose coefficients (DCs) for photon external exposures were calculated using the adult male and female mesh-type reference computational phantoms (MRCPs) of the International Commission on Radiological Protection (ICRP) that had been transformed into five non-standing postures (i.e. walking, sitting, bending, kneeling, and squatting). As an extension, the present study was conducted to establish another DC dataset for external exposures to neutrons by performing Monte Carlo radiation transport simulations with the adult male and female MRCPs in the five non-standing postures. The resulting dataset included the DCs for absorbed doses (i.e., organ/tissue-averaged absorbed doses) delivered to 29 individual organs/tissues, and for effective doses for neutron energies ranging from 10-9 to 104MeV in six irradiation geometries: antero-posterior (AP), posteroanterior (PA), left-lateral (LLAT), right-lateral (RLAT), rotational (ROT), and isotropic (ISO) geometries. The comparison of DCs for the non-standing MRCPs with those of the standing MRCPs showed significant differences. In the lateral irradiation geometries, for example, the standing MRCPs overestimate the breast DCs of the squatting MRCPs by up to a factor of 4 due to the different arm positions but underestimate the gonad DCs by up to about 17 times due to the different leg positions. The impact of different postures on effective doses was generally less than that on organ doses but still significant; for example, the standing MRCPs overestimate the effective doses of the bending MRCPs only by 20% in the AP geometry at neutron energies less than 50MeV, but underestimate those of the kneeling MRCPs by up to 40% in the lateral geometries at energies less than 0.1MeV.

Body-size-dependent phantom library constructed from ICRP mesh-type reference computational phantoms

Recently, ICRP Task Group 103 developed new mesh-type reference computational phantoms (MRCPs) for the adult male and female by converting the current voxel-type reference computational phantoms (VRCPs) of ICRP Publication 110 into a high-quality/fidelity mesh format. Utilizing the great deformability/flexibility of the MRCPs compared with the VRCPs, in the present study, we established a body-size-dependent phantom library by modifying the MRCPs. The established library includes 108 adult male and 104 adult female phantoms in different standing heights and body weights, covering most body sizes representative of Caucasian and Asian populations. Ten secondary anthropometric parameters with respect to standing height and body weight were derived from various anthropometric databases and applied in the construction of the phantom library. An in-house program for automatic phantom adjustment was developed and applied for practical construction of such a large number of phantoms in the library with minimized human intervention. Organ/tissue doses calculated with three male phantoms in different standing heights (165, 175, and 190 cm) with a fixed body weight of 80 kg for external exposures to broad parallel photon beams from 0.01 to 104 MeV were compared, observing there are significant dose differences particularly for the photon energies <0.1 MeV in which the organ/tissue doses tended to increase with increasing standing height. In addition, the organ/tissue doses of three female phantoms in different body weights (45, 65, and 140 kg) with a fixed standing height of 165 cm were compared, showing a significant decreasing tendency with increasing body weight for the photon energies <10 MeV. For the higher energies, the opposite trend, interestingly, was observed; that is, the organ/tissue doses tended to increase with increasing body weight. The results, despite the limited number of exposure cases, suggest that the use of the body-size-dependent phantom library can improve the accuracy of individual dose estimates for many retrospective dosimetry studies by taking the body size of individuals into account.

Comparison of neutron and secondary gamma dose assessment using polygon mesh and voxel computational phantoms

The newly developed mesh-type reference computational phantoms (MRCPs) represent the evolution of the previous reference phantoms and a more detailed description of the human body, addressing the voxel reference phantom limitations. These allow for a more accurate dose calculation in the human body, which in some cases results in a significant difference of the calculated quantities. In this work, the absorbed dose calculation due to neutrons and gammas was calculated using a voxel and a mesh-type computational phantom. The goal was to understand how a more accurate description of the human body affects the estimated neutron dose. The phantoms were tested in a real-case scenario: they were placed in front of a neutron Howitzer container model using PHITS. This model corresponds to the neutron Howitzer container at the Neutron Measurements Laboratory of the Energy Engineering Department of the Polytechnic University of Madrid (UPM), and at the time of measurement it was equipped with a 241Am-Be neutron source of 74 GBq in its center. The container allows the source to be in either the irradiation or the storage position. Results show that when dealing with neutrons, the dose deviation when using GOLEM or the MRCP leads to a general 20%–30% deviation that goes up to above 400% in small thin structures such as the eye.

Dose coefficients of mesh-type ICRP reference computational phantoms for external exposures of neutrons, protons, and helium ions

Recently, the International Commission on Radiological Protection (ICRP) has developed the Mesh-type Reference Computational Phantoms (MRCPs) for adult male and female to overcome the limitations of the current Voxel-type Reference Computational Phantoms (VRCPs) described in ICRP Publication 110 due to the limited voxel resolutions and the nature of voxel geometry. In our previous study, the MRCPs were used to calculate the dose coefficients (DCs) for idealized external exposures of photons and electrons. The present study is an extension of the previous study to include three additional particles (i.e., neutrons, protons, and helium ions) into the DC library by conducting Monte Carlo radiation transport simulations with the Geant4 code. The calculated MRCP DCs were compared with the reference DCs of ICRP Publication 116 which are based on the VRCPs, to appreciate the impact of the new reference phantoms on the DC values. We found that the MRCP DCs of organ/tissue doses and effective doses were generally similar to the ICRP-116 DCs for neutrons, whereas there were significant DC differences up to several orders of magnitude for protons and helium ions due mainly to the improved representation of the detailed anatomical structures in the MRCPs over the VRCPs.