Mental Rotation Task Performance Research Articles

Enhanced activity of the left precuneus as a predictor of visuospatial dysfunction correlates with disease activity in rheumatoid arthritis

ObjectiveTo identify the potential diagnostic biomarkers of rheumatoid arthritis (RA) and assess the relation between visuospatial dysfunction and disease activity in RA patients using mental rotation task (MRT)-based functional magnetic resonance imaging (fMRI).MethodsA total of 27 RA patients (11 in remission, 16 in active) and 27 well-matched controls were enrolled. The visuospatial function of the subjects was measured by MRT. Brain activity data were collected using blood oxygen level dependent fMRI technique under MRT. Disease activity score 28 (DAS28) was used to evaluate the disease severity of RA patients. An analysis of the correlations between abnormal visuospatial-related brain regions, MRT performance, and DAS28 was conducted.ResultsRA patients performed worse on MRT than controls. Compared to the control group, RA patients showed enhanced activation in the left precuneus, left superior frontal gyrus and right cingulate gyrus during the rotation task, with left hemisphere dominance. RA patients in active showed enhanced activation in the left precuneus, left middle frontal gyrus and right cingulate gyrus compared to the patients in remission. The left precuneus activation was negatively correlated with MRT accuracy (r = −0.621, p = 0.01) and positively correlated with DAS28 (r = 0.710, p = 0.002), and MRT accuracy was negatively correlated with DAS28 in RA patients (r = −0.702, p = 0.002).ConclusionEnhanced activation of the left precuneus in RA patients affects visuospatial function and is closely related to disease activity. These changes may provide a valuable diagnostic neuroimaging biomarker of RA.

DIFFERENCES BETWEEN MEN AND WOMEN IN COGNITIVE STRATEGIES APPLIED IN MENTAL ROTATION TASKS

This article aims to outline the differences between men and women in cognitive strategies applied in mental rotation task. Mental rotation is recognised among the fundamental processes of spatial thinking. Good ability to assess the spatial relations between oneself and the surrounding makes it possible to take decisions quickly and to act effectively. Mental rotation tasks can be performed in various ways, depending on their type, and with a use of different cognitive strategies. The study explores characteristics of mental rotation task performance specific to women and men. The differences observed in this area are determined by multiple factors. It was pointed out that interactions between biological and environmental factors are of major importance for effective performance in mental rotation tasks. The discussion also focuses on task characteristics possibly determining different results achieved by men and women, and potentially affecting the choice of specific strategies applied in mental rotation tasks. Subsequently, the article reviews the evidence suggesting differences in cognitive strategies used during mental rotation tasks by women and men. It is also pointed out that, in the context of the observed sex-related differences, the type of strategies used are associated with methods of assessing visuospatial material and with task characteristics. The final part presents data from neuroimaging studies investigating brain activity recorded during performance of this type of tasks. The evidence was discussed with reference to sex differences in cognitive strategies applied in mental rotation tasks.

Mental rotation task performance in relation to sexual and gender diversity in Thailand

Neurohormonal theory argues that organizational effects of hormone exposure influence sexual orientation and gender identity, as well as sex differences in visuospatial cognition. This study examined mental rotation task (MRT) performance in a diverse Thai sample (N = 980). Thai culture has several third genders: individuals assigned male at birth (AMAB) who are feminine and attracted to cis men (i.e., sao praphet song); individuals assigned female at birth (AFAB) who are masculine and attracted to feminine individuals (i.e., toms); AFAB individuals who are feminine and attracted to toms (i.e., dees); and sexual orientation categories similar to Western culture (e.g., gay, lesbian, bi). On the MRT, straight cis men outperformed straight cis women. Results were consistent with organizational effects among AMAB individuals, with straight cis men outperforming gay cis men and sao praphet song. Among AFAB individuals, however, only bi and lesbian cis women outperformed dees. Overall, support for neurohormonal theory was limited among AFAB individuals, but MRT performance among AMAB individuals was consistent with organizational effects. This study informs our understanding of visuospatial sex/gender differences and the applicability of neurohormonal theory across cultures.

Brain Activation of Patients With Obsessive-Compulsive Disorder During a Mental Rotation Task: A Functional MRI Study.

Functional neuroimaging studies have implicated alterations in frontostriatal and frontoparietal circuits in obsessive-compulsive disorder (OCD) during various tasks. To date, however, brain activation for visuospatial function in conjunction with symptoms in OCD has not been comprehensively evaluated. To elucidate the relationship between neural activity, cognitive function, and obsessive-compulsive symptoms, we investigated regional brain activation during the performance of a visuospatial task in patients with OCD using functional magnetic resonance imaging (fMRI). Seventeen medication-free patients with OCD and 21 age-, sex-, and IQ-matched healthy controls participated in this study. Functional magnetic resonance imaging data were obtained while the subjects performed a mental rotation (MR) task. Brain activation during the task was compared between the two groups using a two-sample t-test. Voxel-wise whole-brain multiple regression analyses were also performed to examine the relationship between obsessive-compulsive symptom severity and neural activity during the task. The two groups did not differ in MR task performance. Both groups also showed similar task-related activation patterns in frontoparietal regions with no significant differences. Activation in the right dorsolateral prefrontal cortex in patients with OCD during the MR task was positively associated with their total Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) scores. This study identified the specific brain areas associated with the interaction between symptom severity and visuospatial cognitive function during an MR task in medication-free patients with OCD. These findings may serve as potential neuromodulation targets for OCD treatment.

Relationships between ovarian hormone concentrations and mental rotations performance in naturally-cycling women

Circulating gonadal hormones have been linked to variation in the structure and function of the adult human brain, raising the question of how cognition is affected by sex hormones in adulthood. The impacts of progestogens and estrogens are of special interest due to the widespread use of hormone supplementation. Multiple studies have analyzed relationships between ovarian hormones and mental rotation performance, one of the largest known cognitive sex differences; however, results are conflicting. These discrepancies are likely due in part to modest sample sizes and reliance on self-report measures to assess menstrual cycle phase. The present study aimed to clarify the impact of progestogens and estrogens on visuospatial cognition by relating mental rotation task performance to salivary hormone concentrations. Across two studies totaling 528 naturally-cycling premenopausal women, an internal meta-analysis suggested a small, positive effect of within-subjects changes in progesterone on MRT performance (estimate = 0.44, p = 0.014), though this result should be interpreted with caution given multiple statistical analyses. Between-subjects differences and within-subject changes in estradiol did not significantly predict MRT. These results shed light on the potential cognitive effects of endogenous and exogenous hormone action, and the proximate mechanisms modulating spatial cognition.

Left-handers, retrained left-handers and right-handers: A comparative study

Present study was aimed at further extension of the scientific data concerning the influence of retraining in left-handers as well as concerning some disabilities ascribed to the left-handedness. Study participants filled in the questionnaire about the incidence of fears and depression, bedwetting and stuttering, spatial confusion, complaints on weak memory and attention. Responses were analyzed regarding the handedness of the respondents, qualified as left-hander, right-hander and retrained left-hander. The number of reports on bedwetting and slowness in writing, as well as on spatial left/right confusion was found higher in left-handers as compared to right-handers. The number of reports on fears was found higher in retrained left-handers. Left-handers, retrained left-handers and right-handers did not differ in the number of reports on stuttering, depression, week memory and not sustained attention. Mental rotation task performance was studied in another group of left-handed and right-handed participants. Handedness was determined by the test on hand performance. Left-handers were found to make more mistakes in mental rotation task performance as compared to right-handers. We conclude that expectancy of bedwetting, slowness in writing and mental spatial left/right confusion is higher in left-handers as compared to right-handers. Retraining of left-handers is suggested to cause fears, however it is not related to stuttering, depression, slowness in reading and writing, worsening of memory and attention. Stuttering is equally expectable among left-handers, retrained left-handers and right-handers.

Manipulation ability of internal representation in patients with euthymic bipolar I disorder and schizophrenia using a mental rotation task.

A growing body of literature has suggested that effective emotion regulation is influenced by cognitive function. Maintenance and manipulation of internal representations occur in working memory (WM), and impairments of WM have been reported in patients with bipolar disorder. We examined the manipulation ability of internal representations in WM using mental rotation (MR) tasks, and compared the task performances of euthymic bipolar I disorder patients to those of schizophrenia patients and healthy controls. In this study, 20 euthymic bipolar I disorder patients, 20 schizophrenia patients, and 38 healthy controls were recruited. People and letter MR tasks were employed to evaluate the ability of WM manipulation. Compared to healthy controls, euthymic bipolar I disorder patients showed substantially higher error rates of people MR task and slower responses in both people and letter MR tasks. Schizophrenia patients showed no difference in error rate and response time in MR tasks compared to healthy controls; however, they showed significantly slower responses in people MR task compared to controls. MR task performance was not different between euthymic bipolar and schizophrenia patients. Our study results indicate that manipulation of internal representation, especially in the egocentric MR, is impaired in bipolar disorder even in the emotionally-stable state. We speculate that impaired imagery manipulation might be related to alterations in empathic ability, susceptibility of mental imagery, and emotion regulation strategies observed in bipolar disorder.

The Mental Rotation Ability of Expert Basketball Players: Identifying On-Court Plays

ABSTRACT Purpose: The purpose was (1) to test a new version of a mental rotation task (MRT), which assesses mental rotation abilities of men and women for sport-specific items, and (2) to investigate potential differences in MRT performance, which are based on athletic expertise. Methods: Eighty-eight basketball experts (42 females) and 123 novices (64 females) were tested with a paper-and-pencil version of the “Mental Rotation Task—Basketball (MRT-BB)”, which is similar to the original MRT. Instead of three-dimensional cubes, six different basketball plays were used as stimuli. The criterion stimulus of the 24 items was always displayed in an upright orientation (basket on top), located on the left side of the sheet. In addition, two “correct” alternatives (one stimulus rotated by 90° to the left or right and one by 180°) and two “incorrect” alternatives (either rotated mirror-images of the criterion stimulus or rotated images of a different play) were displayed in different positions of the same row. The task was to identify the “correct” alternatives. Results: Results demonstrated (a) an effect of sex, with more items solved for male participants as compared to female participants, and (b) an effect of expertise, with better performance of expert players than of novices. Conclusions: Male and female basketball experts show better mental rotation skills for sport-specific stimulus material. The MRT-BB extends standard tests of mental rotation to sport-specific stimulus material and can be used to test the sport-specific mental rotation skills of basketball players.

Game-Based Multimodal Representations and Mathematical Problem Solving

This mixed-method study aims to explore the feasibility of using the game-based, multimodal representation of mathematical problems to support middle school students’ practice and performance of math problem representation and solving. A three-dimensional architectural simulation game, called E-Rebuild, was developed to engage students in architecture-themed math problem solving and learning. Based on the data collected from 56 middle graders, the study findings suggested that interacting with game-based multimodal math problems helped students develop a systematic perspective and an analytical demeanor in coordinating external problem representations distributed across game objects and actions. Game-based problem solving promoted participants’ mathematical test performance as well as mental rotation task performance.

Associations between empathizing-systemizing cognitive style and mental rotation task performance among homosexual men and women in China

Empathizing-systemizing cognitive style is related to mental rotation ability among heterosexuals. We sought to determine whether there is also an association between a measure of empathizing-systemizing and mental rotation task performance via the Internet among homosexual men and women (372 men and 469 women) in China. We found that systemizing, but not empathizing, scores were positively correlated with mental rotation task performance in both homosexual men and women. When comparing by cognitive style, we found that homosexual individuals with a systemizing cognitive style performed significantly better on the mental rotation task than did those with an empathizing style. Our results indicate a consistency across cultures and sexual orientations in the association between systemizing and mental rotation task performance.

Progesterone and mental rotation task: is there any effect?

Mental rotation task (MRT) incorporates elements of spatial abilities, important in many professions, with people of both genders involved. Importantly, these are the areas where spatial tasks might be performed for long time periods; thus adverse effects of mental fatigue are highly unwanted. Substantial variation of MRT performance in relation to estrogen levels has been observed in many studies, whereas the role of progesterone remains elusive. Here we aimed to elucidate the effect of progesterone level on the long-duration (1.5 hours) performance of MRT. We included three groups of subjects: a group of males as a control, a group of females in their follicular phase (low progesterone) and a group of females in their luteal phase (high progesterone), MRT accuracy and response time, subjective fatigue ratings and cardiovascular measures together with 17β-estradiol and progesterone concentrations were analyzed. We found that subjective ratings of fatigue increased, performance accuracy increased, and mean response times decreased during the task in all groups. Females in luteal phase were significantly slower not only than men, but also than females in their follicular phase. An increase in subjective fatigue ratings was positively related to progesterone level—at higher progesterone levels, females felt more tired.

Continuous-combined oral estradiol/drospirenone has no detrimental effect on cognitive performance and improves estrogen deficiency symptoms in early postmenopausal women

This study aimed to explore the effects of continuous-combined estradiol 1 mg/drospirenone 2 mg (E2D) on cognitive performance in healthy, recently postmenopausal women. A 6-month randomized, double-blind, placebo-controlled study was carried out in a university research center. Participants were 23 healthy postmenopausal women aged 49 to 55 years. Cognitive performance was assessed with a computerized cognitive battery administered to all participants on 0, 12, and 26 weeks. Functional magnetic resonance imaging was performed on 13 participants before and after treatment using tasks of verbal fluency and mental rotation. E2D was not associated with an overall effect on cognitive performance. Functional magnetic resonance imaging results showed no difference between the groups for verbal fluency or mental rotation task performance at baseline. The mental rotation task was associated with increased blood oxygen level-dependent signalling in the placebo group in both occipital lobes and in the left superior parietal lobe after 26 weeks (P < 0.05), with no changes over time seen in the treatment group. The total menopausal symptom and sexual function domain scores improved after treatment in women randomized to E2D compared with the placebo group (both P < 0.05). Similarly, systolic blood pressure, weight, and body mass index were significantly lower in women randomized to E2D at 26 weeks (P < 0.05). E2D has no detrimental effect on cognitive performance in early postmenopausal women. E2D significantly improves menopausal symptoms, sexual function, systolic blood pressure, and weight.

Visual-spatial cognition in women with polycystic ovarian syndrome: the role of androgens

Are women with polycystic ovary syndrome (PCOS) better at three-dimensional mental rotation than other women? Women with PCOS scored significantly higher on a mental rotation task than a female control group. PCOS is a condition characterized by elevated testosterone levels. Some researches have found that three-dimensional mental rotation task performance is positively correlated with testosterone levels. This cross-sectional study was conducted between June 2006 and January 2009. The participants were 69 women with PCOS and 41 controls recruited from five gynaecology clinics in London. The control group consisted of non-PCOS women of comparable subfertility to PCOS group. These groups sizes gave roughly 80% power to detect moderate effect sizes for the main statistical test. Participants were recruited at London gynaecology clinics. The women were aged between 18 and 43. PCOS was diagnosed based on the Rotterdam criteria. Controls were women who experienced some degree of subfertility. Blood samples from participants were frozen for up to 4 months until being assayed by direct electrochemiluminescence. The mental rotation task was undertaken electronically. Some questionnaires and other tasks were completed as control measures. Women with PCOS scored significantly higher than controls: median (range) 3.00 (0-9) and 2.00 (0-8), respectively (U = 1147.500, N1 = 69, N2 = 41, P < 0.047). Within the PCOS group, circulating levels of testosterone were significantly positively correlated with three-dimensional scoring (rs = 0.376, n = 56, P < 0.002), whereas estradiol was significantly negatively correlated with three-dimensional scoring (rs = -0.473, n = 29, P < 0.010). In the control group, the relationship between sex hormones and mental rotation was non-significant. Other factors, including general intelligence and social class, did not account for these findings. A subgroup analysis comparing hyperandrogenic PCOS cases, non-hyperandrogenic PCOS cases and controls, in which age and body mass index were controlled for using ANCOVA, found a non-significant difference in three-dimensional scoring between the three groups (F = 1.062, d.f. = 1, 73, P < 0.351). The small number of women in the control group meant that correlations were underpowered in this group. This study is the first to find a benefit of PCOS in visuospatial cognition, and the first to find a link between visuospatial cognition and sex hormones in PCOS. The fact that the correlations went in the opposite direction in the PCOS group compared with the controls might suggest the influence of increased prenatal exposure to androgen in PCOS. The assays for this study were funded by the Department of Psychology, City University London. All authors report no conflicts of interest.

The influence of body position and spatial orientation of an object on mental rotation task's performance

The research question is the way the mind deals with the mental rotation of visual objects depending on the observer's body position and the spatial orientation of these objects. In the light of the experiment's data, there are no differences between subjects rotating objects in the vertical or horizontal body position and between subjects rotating objects presented in objectively different orientations. Only interaction between body position and an object's orientation significantly modified the process of its mental rotation. When we are lying down on one side, then all our representations of the real-world objects have a natural tendency to lay down on the same side. This is good evidence for the mental representation's embodiment.

Oral contraceptives and androgenicity: Influences on visuospatial task performance in younger individuals.

The current study investigated whether the androgenic activity of oral contraceptives (OC) mediates performance on sexually dimorphic cognitive tasks in 155 younger individuals. Participants were categorized by hormonal contraceptive use (user vs. nonuser) and the androgenic activity of each OC (OC generation). OC generation was determined based on previous research in which users are grouped based on the type of progestin contained in each OC. Cognitive tasks included the mental rotation task (MRT) and a recognition memory task. In addition, we examined the correlates of both menstrual cycle phase and OC use, such as mood, premenstrual syndrome, depression, blood pressure, and body fat using standardized measures. The main result was that OC androgenicity influenced MRT performance. Second generation OCs are the most androgenic. Thus, MRT performance was best in these OC users as compared to third generation users, Yasmin users and nonusers. On the other hand, Yasmin, a newer generation of OC, contains an "antiandrogenic" progestin, dropirenone. Yasmin users not only performed more poorly on the MRT in comparison to second and third generation pill users, but they performed significantly worse than OC nonusers. Results show that the androgenic activity in OCs influences MRT performance in the presence of static estrogen levels. Overall, the resulting pattern is consistent with a broad range of results demonstrating that visuospatial performance may be enhanced in women who are exposed to androgenic treatments. Furthermore, visuospatial performance is hindered with the introduction of antiandrogenic preparations.

The Effects of Sex, Sexual Orientation, and Digit Ratio (2D:4D) on Mental Rotation Performance

In spite of the reduced level of experimental control, this large scale study brought some clarity into the relation between mental rotation task (MRT) performance and a number of variables where contradictory associations had previously been reported in the literature. Clear sex differences in MRT were observed for a sample of 134,317 men and 120,783 women, with men outperforming women. There were also MRT differences as a function of sexual orientation: heterosexual men performed better than homosexual men and homosexual women performed better than heterosexual women. Although bisexual men performed better than homosexual men but less well than heterosexual men, no significant differences were observed between bisexual and homosexual women. MRT performance in both men and women peaked in the 20-30 year range, and declined significantly and markedly thereafter. Both men and women showed a significant negative correlation between left and right digit finger ratio and MRT scores, such that individuals with smaller digit ratios (relatively longer ring finger than index finger) performed better than individuals with larger digit ratios.

Spatial task performance, sex differences, and motion sickness susceptibility.

There are substantial individual differences in susceptibility to motion sickness, yet little is known about what mediates these differences. Spatial ability and sex have been suggested as possible factors in this relationship. 89 participants (57 women) were administered a Motion Sickness Questionnaire that assesses motion sickness susceptibility, a Water-level Task that gauges sensitivity to gravitational upright, and a Mental Rotation Task that tests an individual's awareness of how objects typically move in space. Significant sex differences were observed in performance of both the Water-level Task (p<.01), and the Mental Rotation Task (p<.005), with women performing less accurately than men. Women also had significantly higher scores on the Motion Sickness Questionnaire (p<.005). Among men, but not women, significant negative relationships were observed between Water-level Task performance and Motion Sickness Questionnaire score (p<.001) and between Mental Rotation Task performance and Motion Sickness Questionnaire score (p<.005). In conclusion, women performed significantly more poorly than men did on the spatial ability tasks and reported significantly more bouts of motion sickness. In addition, men showed a significant negative relationship between spatial ability and motion sickness susceptibility.

SPATIAL TASK PERFORMANCE, SEX DIFFERENCES, AND MOTION SICKNESS SUSCEPTIBILITY

There are substantial individual differences in susceptibility to motion sickness, yet little is known about what mediates these differences. Spatial ability and sex have been suggested as possible factors in this relationship. 89 participants (57 women) were administered a Motion Sickness Questionnaire that assesses motion sickness susceptibility, a Water-level Task that gauges sensitivity to gravitational upright, and a mental Rotation Task that tests an individual's awareness of how objects typically move in space. Significant sex differences were observed in performance of both the Water-level Task (p<.01), and the Mental Rotation Task (p<.005), with women performing less accurately than men. Women also had significantly higher scores on the Motion Sickness Questionnaire (p<.005) Among men, but not women, significant negative relationships were observed between Water-level Task performance and Motion Sickness Questionnaire score (p<.001) and between Mental Rotation Task performance and Motion Sickness Questionnaire score (p<.005). In conclusion, women performed significantly more poorly than men did on the spatial ability tasks and reported significantly more bouts of motion sickness. In audition, men showed a significant negative relationship between spatial ability and motion sickness susceptibility.

Autonomic physiological activity in mental rotation tasks.

The electrodermal response (EDR) during a mental rotation (MR) task performance was investigated. For 6 males and 8 females (16-25 years old) there was a progressive increase in the number of EDRs as the angle of rotation (complexity) of the task was increased. These results support previous findings that autonomic physiological activity varies with the amount of information processing or its difficulty.

Mental Rotation at 7 Years - Relations with Prenatal Testosterone Levels and Spatial Play Experiences

Biological and social-experiential factors appear to play a role in the male advantage in spatial abilities. In the present study, relations among prenatal testosterone levels, spatial play experiences, and mental rotation task performance were explored in 7-year-old boys and girls. A positive correlation was observed between prenatal testosterone levels and rate of rotation in girls. The findings were less clear for boys, but suggested the opposite pattern of results. Relations between spatial play preferences and mental rotation task performance were not observed in children of either sex. These findings are consistent with the hypothesis that testosterone acts on the fetal brain to influence the development of spatial ability.