Well-being Of Men Research Articles

Semaglutide, Testosterone and Sildenafil advertising on social media: The Normalisation of lifestyle enhancement drugs

Recently, there has been a sharp increase in advertising for the ‘prescription-only’ medicines semaglutide and testosterone on social media platforms in the UK, along with the ‘pharmacy medicine’ sexual enhancer Sildenafil. These promoted adverts appear to come from both legitimate clinics in the case of testosterone replacement therapy (TRT) and Sildenafil, and illicitly operating suppliers with the attempted appearance of legitimacy in the case of semaglutide. This commentary explores the extent to which the prevalent advertising of these lifestyle medicines on social media is normalising their use, and the potential harms associated with each.For testosterone / TRT, we consider the over-medicalisation of men's general wellbeing concerns and potential harms relating to dependency if use is promoted and encouraged beyond medical need, paralleling prior observations for the sexual enhancer sildenafil. This is followed by an exploration of harms relating to black market semaglutide supply on social media to individuals who are often unaware they are not accessing legitimate pharmaceutical product, including the dangers of product contamination and substitution, as well as uninformed use linked to a lack of information on safe dosages provided by suppliers. Following these discussions, this commentary examines the potential harm reduction impacts that direct to consumer (DTC) supply of prescription medicines could have, and considers how policy could encourage these beneficial effects without further normalising or encouraging drug use in otherwise healthy individuals. However, we also note the importance of tackling prevailing cultural pressures towards lifestyle drug use and the need to address these through education and similar policies.

THE ANALYSIS STUDY OF EFFECTIVENESS AND SAFETY OF ORAL SILDENAFIL CITRATE FOR TREATMENT OF ERECTILE DYSFUNCTION : A COMPREHENSIVE SYSTEMATIC REVIEW

Background: Erectile dysfunction (ED) is a medical condition affecting men's sexual performance and well-being. Sildenafil citrate, a specific inhibitor of phosphodiesterase type 5, is approved for treating ED. The efficacy and safety of oral sildenafil citrate in treating ED are crucial for successful treatment procedures. Understanding the relationship between the efficacy and safety of oral sildenafil citrate can help develop successful treatment procedures for ED patients. Methods: This systematic review adhered to the PRISMA 2020 guidelines and primarily examined entire English literature published between 2000 and 2024. Only editorials and review articles published in the same publication as the submission were accepted if they possessed a Digital Object Identifier (DOI). A variety of online platforms, including ScienceDirect, PubMed, and SagePub, were utilized to gather the relevant literature. Result: The study analyzed more than 2000 papers from reputable sources such as Science Direct, SagePub, and PubMed. After deciding to subject eight publications to additional inspection, a thorough evaluation of the entire body of literature was carried out. Conclusion: Sildenafil, a potent treatment for erectile dysfunction (ED), has been found to be effective in improving men's psychosocial aspects. It is an inhibitor of PDE5, a condition that affects men's emotional well-being. The study also found that the firmness of erections was linked to improvements in psychosocial aspects. Sildenafil can be used interchangeably with tablets, providing a convenient alternative for those with difficulty swallowing. However, follow-up for men with ED is often inadequate due to improper doses and lack of understanding.

Osthole Suppresses Cell Growth of Prostate Cancer by Disrupting Redox Homeostasis, Mitochondrial Function, and Regulation of tiRNAHisGTG.

Prostate cancer remains a significant global health concern, posing a substantial threat to men's well-being. Despite advancements in treatment modalities, the progression of prostate cancer still presents challenges, warranting further exploration of novel therapeutic strategies. In this study, osthole, a natural coumarin derivative, inhibited cell viability in cancer cells but not in the normal prostate cell line. Moreover, osthole disrupted cell cycle progression. Furthermore, osthole reduces mitochondrial respiration with mitochondrial membrane potential (ΔΨm) depolarization and reactive oxygen species (ROS) generation, indicating mitochondrial dysfunction. In particular, osthole-induced ROS generation was reduced by N-acetyl-L-cysteine (NAC) in prostate cancer. In addition, using calcium inhibitors (2-APB and ruthenium red) and endoplasmic reticulum (ER) stress inhibitor (4-PBA), we confirmed that ER stress-induced calcium overload by osthole causes mitochondrial dysfunction. Moreover, we verified that the osthole-induced upregulation of tiRNAHisGTG expression is related to mechanisms that induce permeabilization of the mitochondrial membrane and calcium accumulation. Regarding intracellular signaling, osthole inactivated the PI3K and ERK pathways while activating the expression of the P38, JNK, ER stress, and autophagy-related proteins. In conclusion, the results suggest that osthole can be used as a therapeutic or adjuvant treatment for the management of prostate cancer.

Psychological impact of urological disorders on men's mental health: the need for integrated support

Urological disorders impact men's physical health and mental wellbeing, necessitating integrated mental health support within urology. This article examines the psychological distress associated with conditions like prostate cancer and erectile dysfunction, compounded by societal expectations that often discourage men from seeking help. It highlights the importance of a holistic care model that addresses physical symptoms and psychological impacts. The authors advocate for a paradigm shift towards comprehensive care, enhanced training for urologists and dismantling societal stigma to improve patient outcomes and establish a new standard in men's health care.

A Human Volunteer Study of Nutraceutical Product ‘Rekindle for Men’

Successful randomized observational data provide strong experimental evidence to prove the efficacy of Rekindle for Men. Arelang Naturals Private Limited brings natural ingredients for immunity and to promote the overall well-being of Men’s health. Nutritional supplements from plant-based enriched extracts have been used in the form of a cocoa bars. Rekindle for men is a nutraceutical product comprising Safed musli (Chlorophytum borivillinum), Ashwagandha (Withania somnifera), Ginseng (Panax ginseng), Gokhru (Tribulus terristris), Vidarikand (Pureria tuberosa), Kapikacchu (Mucuna pruriens), Jaiphal (Myristica fragrans), Ginkgo biloba and Saffron (Crocus sativus) which help in elevating mood, energy and primal impulses. The present study will help in knowing the use of a nutritional supplement in cocoa bars chocolate form for men’s health. The data is statistically significant and enough for assessing the effect of nutritional supplements on better health and overall immunity.

Positive Body Image and Psychological Wellbeing among Women and Men: The Mediating Role of Body Image Coping Strategies.

This study aimed to examine the mediating role of body image coping strategies in the relationship between positive body image and wellbeing. Three hundred and seventy-two women and three hundred and seventy-seven men completed a questionnaire assessing body appreciation, body appreciation functionality, body compassion, body image coping strategies (appearance fixing, avoidance, positive rational acceptance), self-acceptance and overall psychological wellbeing. Path analysis showed that avoidance significantly mediated the relationship between body appreciation and overall psychological wellbeing among both women and men; its mediating role was confirmed for men's but not for women's self-acceptance. Positive rational acceptance was a significant mediator of the relationship between body compassion and both psychological wellbeing and self-acceptance among men but not among women. These findings show that higher body appreciation is associated with a lower tendency to avoid appearance-related cognitions or thoughts that are interpreted as threatening, with an indirect effect on women's and men's psychological wellbeing. Analogously, but only for men, body compassion is associated with mental activities and self-care behaviors that foster rational self-talk and the acceptance of one's experiences, which, in turn, are linked to higher wellbeing. These findings can help to plan programs aimed at fostering individuals' wellbeing by focusing on their positive body image considering gender differences.

Mentorship for young gay men in Hong Kong: A pilot mixed-methods randomized controlled trial.

This study examined whether mentorship could promote young gay men's identities and well-being, and whether a mentor's sexual orientation matters. A randomized control trial compared outcomes across three conditions: Arm A (a mentee matched with a sexual minority mentor), Arm B (a mentee matched with a heterosexual mentor), and a control arm receiving psychoeducation only. A community sample of 60 mentees aged 18-25 years was randomly allocated to the three arms and completed questionnaires at baseline, 3 months into the intervention, and at the end of the 6-month program. Fifteen mentees recounted their mentoring experiences through in-depth interviews. Linear mixed effects models showed that for both intervention and control conditions, internalized homonegativity declined while resilience, loneliness, and body acceptance improved over time. No time and group interactions were found. Meanwhile, a mentor's sexual orientation did not drive differential quality and outcomes of mentorship. Interviewees cited various benefits of mentorship, including providing companionship, enriching connection with lesbian, gay, bisexual (LGB) communities, and adding knowledge and perspectives of LGB lives and identities. Although quantitative data did not support any exclusive benefits of mentorship, most mentees recognized mentorship as a vital source of affirmation and companionship. Implications for research and mentoring programs are discussed.

Men's physical health and life history transitions in the Philippines: Evidence for ‘marital selection’ but not protective effects of partnering and fatherhood

In Euro-American societies, married people typically have lower overall risks for total mortality and for certain chronic conditions compared to non-married people. However, people becoming partnered and parents also tend to gain weight in Euro-American settings. Few studies have tested whether links between physical health and life history status translate to other cultural contexts where the socio-ecological dynamics of family life may differ. This limits the application of these insights to men's well-being in global public health. To help address this gap, we drew on a large, long-running birth cohort study of Filipino men, using data collected at three waves between 2005 and 2014 when men were 21.5–30.5 years old (N = 607, obs. = 1760). We tested for the effects of the transition to partnering (marriage/cohabitation) and fatherhood on men's physical health (waist circumference, fat-free mass index, and grip strength). Men becoming partnered or partnered fathers (P/PF) had comparable longitudinal physical health trajectories to men remaining single non-fathers. However, men who became P/PF by their mid 20s had higher fat-free mass index values than single non-fathers at each wave, with the largest effect observed when all men were single non-fathers at baseline. Men who became P/PF by their early 30s were also stronger than the reference group at baseline. Thus, men who were more muscular and stronger at baseline were more likely to transition to P/PF status, consistent with a ‘marital selection’ model. In complementary analyses, men did not exhibit adverse health effects when they became partnered fathers as young adults or parents to infants, respectively. These findings suggest that links between health and life history transitions in this setting differ from those commonly observed in Euro-American societies. While transitions to marriage and fatherhood are promising windows for interventions to improve men's health, our results highlight the importance of tailoring such approaches to local dynamics.

Unlocking the Path to Healthier Families: The Untapped Potential of Men's Preconception Health.

This debate paper explores the necessity of introducing a comprehensive primary care model for men's preconception health. It highlights the importance of a holistic approach that includes risk assessment, health promotion, and clinical and psychological interventions. Despite the current limited focus on male preconception health in primary care, there is evidence suggesting a growing awareness among men about the importance of optimizing their health before conception. The paper stresses the importance of such a model in addressing various aspects of men's well-being, family dynamics, and overall reproductive health outcomes. It also acknowledges potential limitations and considerations related to implementing this crucial healthcare approach.

Social connectedness and surviving at the margins: Findings from interviews with low-income Latino men in the U.S. Northeast.

Structural and interpersonal discrimination can lead to social exclusion and limited social integration, inhibiting the use of support networks to gain access to health-protective material and social resources. Social support theories suggest that connectedness may moderate the link between discrimination and health risk. This study examined how risk factors (i.e., structural and interpersonal discrimination) further marginalize Puerto Rican men by limiting access to social support. We also aimed to identify resiliency factors, such as cultural values related to social interactions and community support, which may be protective for these men's well-being. We conducted 40 semistructured interviews with a stratified purposeful sample of Puerto Rican (92.5%) men aged 25-70 (Mage = 50.7) in the U.S. Northeast. A hybrid deductive and inductive thematic qualitative analysis was used to analyze data. Participants discussed how structural and interpersonal discrimination result in inequities and barriers to resources and services (e.g., lack of adequate shelter, insecurity, employment) which impacted their well-being through the inability to access fundamental support for survival. The men identified cultural values (e.g., familismo, simpatía) and emphasized the importance of community support as protective factors that may provide a respite from the difficulties of navigating discrimination experiences. Findings suggest discrimination limits Puerto Rican men's ability to access resources, which has a detrimental impact on their well-being. Identifying social support beyond the family, and considering cultural values related to support, can enhance community interventions by focusing on incorporating multiple forms of support that may improve Puerto Rican men's health. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

CBPH assay for the highest sensitive detection of SARS-COV-2 in the semen

BackgroundGreat concerns have been raised on SARS-CoV-2 impact on men's andrological well-being, and many studies have attempted to determine whether SARS-CoV-2 is present in the semen and till now the data are unclear and somehow ambiguous. However, these studies used quantitative real-time (qRT) PCR, which is not sufficiently sensitive to detect nucleic acids in clinical samples with a low viral load. MethodsThe clinical performance of various nucleic acid detection methods (qRT-PCR, OSN-qRT-PCR, cd-PCR, and CBPH) was assessed for SARS-CoV-2 using 236 clinical samples from laboratory-confirmed COVID-19 cases. Then, the presence of SARS-CoV-2 in the semen of 12 recovering patients was investigated using qRT-PCR, OSN-qRT-PCR, cd-PCR, and CBPH in parallel using 24 paired semen, blood, throat swab, and urine samples. ResultsThe sensitivity and specificity along with AUC of CBPH was markedly higher than the other 3methods. Although qRT-PCR, OSN-qRT-PCR and cdPCR detected no SARS-CoV-2 RNA in throat swab, blood, urine, and semen samples of the 12 patients, CBPH detected the presence of SARS-CoV-2 genome fragments in semen samples, but not in paired urine samples, of 3 of 12 patients. The existing SARS-CoV-2 genome fragments were metabolized over time. ConclusionsBoth OSN-qRT-PCR and cdPCR had better performance than qRT-PCR, and CBPH had the highest diagnostic performance in detecting SARS-CoV-2, which contributed the most improvement to the determination of the critical value in gray area samples with low vrial load, which then provides a rational screening strategy for studying the clearance of coronavirus in the semen over time in patients recovering from COVID-19. Although the presence of SARS-CoV-2 fragments in the semen was demonstrated by CBPH, COVID-19 is unlikely to be sexually transmitted from male partners for at least 3 months after hospital discharge.

‘Joy, not sorrow’: Men's perspectives on gender, violence, and cash transfers targeted to women in northern Ghana

Evidence indicates that cash transfers can decrease intimate partner violence (IPV) against women, although most research has focused on women's perspectives and experiences, with less attention to men. We analyzed data from four focus group discussions with male partners of women who participated in the Ghana Livelihood Empowerment Against Poverty (LEAP) 1000 cash transfer program. We elicited men's perceptions of poverty, relationship dynamics, IPV and cash transfers targeted to their wives using thematic analysis. Men largely viewed the effects of the cash transfer as positive – they felt decreased provider role strain when women used the cash to cover household expenses such as food and school fees. Men also indicated that they felt respected when women used the cash to cover sudden expenses, such as funeral costs, thus preventing the need to borrow from community members and exposing their inability to fulfill provider roles. These feelings of relief and respect helped improve men's overall wellbeing, their marital relationships and reduced the potential for IPV. Despite these positive results, men revealed that they still expected to be informed and consulted about the transfer and its expenditure, and felt disrespected when women did not do so, thus heightening the potential for household conflict. Further research and innovation in programming is needed to integrate gender transformative strategies into cash transfer programs, explicitly aimed at changing gender norms to enhance and sustain beneficial impacts on gender relations and IPV.

New directions in male-tailored psychotherapy for depression.

Societal, cultural, and contextual norms about how men should be and behave (so called traditional masculinity ideologies; TMI) affect men's presentation of depressive disorders, psychotherapy use, and treatment engagement. Only recently, however, male-tailored psychotherapy approaches for depressive disorders have been developed, which aim to systematically soften dysfunctional TMI. In this review, we outline the necessary groundwork as well as recent advances in research on TMI, men's help-seeking, male depression, and their interrelatedness. Subsequently, we discuss the potential value of these findings for male-tailored psychotherapy for depressive disorders. A preliminary evaluation of a male-specific psychoeducation program found that a male-specific psychoeducation text could reduce negative affect as well as state shame and potentially elicit a shift from externalizing depression symptoms toward more prototypical depression symptoms. The James' Place program, a male-tailored community-based service, improved suicidal men's overall well-being, problems, functioning, and suicide risk. The Heads Up Guys! program, an eHealth resource aimed at depressed men, reported a high and increasing global interest in their website, with considerable visitor engagement. The Man Therapy online resource improved depressive symptoms, suicidal ideation, and help-seeking behavior. Finally, the Men in Mind program, an online training program for clinical practitioners, increased practitioners' capacity to engage and support men in therapy. Male-tailored psychotherapy programs for depressive disorders, which are informed by recent advances in TMI research, may potentially increase therapeutic effectiveness, engagement, and adherence. While recent preliminary analyses of individual male-tailored treatment programs show promising results, extensive and systematic primary studies evaluating these programs are pending but greatly needed.

Gender, life events, and mental well-being in emerging adulthood.

Emerging adulthood is a critical period of life involving many life transitions that may generate stress and compromise health and mental well-being. To know the most frequent life events of women and men in emerging adulthood, analyzing also the relevance that such stressors have on their psychological well-being and life satisfaction. A second aim is to determine the relevance of age, educational level, most frequent life events, coping styles, and perceived social support as risk and protective factors for well-being. The sample consisted of 2,000 individuals from the general Spanish population (55% women), aged between 18 and 29, who were assessed using five questionnaires and scales measuring life events, coping styles, life satisfaction, psychological well-being, and social support. The findings showed that 90% of the sample had experienced one or more life events during the previous year and that a higher number of life events experienced over the past year was associated with lower mental well-being. Multiple regression analyses made clear that, although some events experienced in the previous year (namely, family conflicts and change in the relationship with parents) were associated with lower women's and men's well-being, the most important determinants of well-being in either gender were coping styles; however, some predictors of women's well-being proved different from those of men. In the case of women, family and intimate partner conflicts predicted lower life satisfaction and psychological well-being was lower in the case of family conflicts. As for men, work or academic life events predicted lower life satisfaction. These research findings are relevant for the design of programs and strategies to improve mental well-being in emerging adulthood.

Australian Men’s Sheds and Their Role in the Health and Wellbeing of Men: A Systematic Review

Men’s sheds are a community-based organisation that allows a space for a community of men to interact and engage with one another with hands-on activities. As such, men’s sheds form an appropriate setting to deliver health and wellbeing initiatives. This review aims to understand the role of Australian men’s sheds with respect to the health and wellbeing of their male participants. This review was conducted in accordance with the preferred reporting items for systematic reviews and meta-analysis (PRISMA) following a three-step process of planning, conducting, and reporting the review. All three authors reviewed all the eligible articles. There was significant methodological heterogeneity between the sources identified (n = 11). A narrative synthesis identified three key themes: health promotion, wellbeing, and socialisation; intergenerational mentoring; and Aboriginal and Torres Strait Islander men’s health. Men’s sheds serve as ideal locations for the delivery of initiatives that can positively impact on the health and wellbeing of their male participants. Furthermore, research is needed to explore the implementation and evaluation of these health and wellbeing initiatives for men in their respective communities.

Effect of Yoga on Psychological Well-Being in Men

Abstract: Retirement brings a major transition in life. This transition may affect a retired person’s physical, mental, and social health and lead to psychological problems. This study investigated the effects of Yoga on the well-being of retired men. It was a nonrandomized study involving 90 retired men aged 60–75 years following purposive sampling. The 14-week intervention included a daily session of 90 minutes at a yoga training center in Pune, India. Each session comprised light exercises, loosening, breathing exercises, relaxation, and meditation. Ryff’s validated scale was used to measure psychological well-being in six domains. The data were analyzed using a t-test. Integrated yoga practice showed a significant improvement in well-being ( p < .05), proving Yoga can be useful for improving the psychological well-being of retired people. The findings of this study should be implemented in a larger group of people for assessing and improving psychological well-being.

Ethnobotanical study of medicinal plants traditionally used against erectile dysfunction in Tabora region, Tanzania

Background: Globally, erectile dysfunction (ED) is a public health concern that upsets men's psychosocial well-being. Despite using indigenous knowledge to manage various disorders in Tanzania, there is a lack of data on the medicinal plants (MPs) used to manage ED. Therefore, this study was aimed at documenting MPs traditionally used by traditional healers (THs) to manage ED in Tabora region, Tanzania. Methods: An ethnobotanical survey was conducted from June to October 2020. A semi-structured questionnaire was used to collect information from 38 THs in 9 wards, explicitly asking about MPs used against ED, parts used, methods of preparation, and routes of administration. The collected information was analyzed by computing percentage frequencies and familiarity index. Results: Thirty-four plant species belonging to 21 families and 32 genera were documented to be used to manage ED. Family Fabaceae (26%) dominated the species used in the treatments. Abrus precatorius L. (59%), Senegalia senegal (L.) Wild., Ricinus communis L. (with 57% each), Coffea arabica L., and Flueggea virosa (Willd.) Voigt. (56% each) were the most cited MPs. Tree (52%) and root (60%) were the most utilized growth form and plant part, respectively. Decoction (34%) and oral (97%) were the most used methods of preparing and administering the remedies, respectively. Conclusion: The findings indicate that the region has diverse MPs for treating ED. Most MPs used by THs to treat ED are yet to be tested; thus, further research is required to authenticate the efficacy of the herbal remedies and to formulate low-cost contemporary drugs. Keywords: Ethnomedicine, herbal remedies, impotence, Traditional medicine, Tanzania

Posttraumatic Growth and Subjective Well-Being in Men and Women after Divorce: The Mediating and Moderating Roles of Self-Esteem

Prior research has mainly examined non-adaptive responses to divorce, with less attention being paid to positive changes following the adversity of marital dissolution, especially posttraumatic growth and its consequences. The aim of this paper was to analyse the relationship between posttraumatic growth and subjective well-being, as well as the mediating and moderating role of self-esteem in this relationship among divorced men and women. The sample consisted of 209 divorcees (143 females, 66 males) aged 23-80 (M = 41.97, SD = 10.72). The Posttraumatic Growth Inventory (PTGI), the Oxford Happiness Questionnaire (OHQ) and the Rosenberg Self-Esteem Scale (SES) were used in the study. Positive associations between overall posttraumatic growth, specific growth dimensions, subjective well-being and self-esteem were found. Self-esteem was confirmed as a mediator in the relationships between changes in perception of self and subjective well-being (SWB), between changes in relating to others and SWB and between appreciation for life and SWB. Self-esteem moderated the association between spiritual changes and subjective well-being; namely, changes in spirituality were positively related to happiness in individuals with lower and average self-esteem but not with high self-esteem. We found no differences between women and men in the obtained results. Self-esteem might be considered a possible psychological (mediating rather than moderating) mechanism in the transmission of PTG onto SWB in divorcees, regardless of their gender.

Status quo and predictors of Weibo users' attitudes toward lesbians and gay men in 31 provinces in the Chinese mainland: Analysis based on supervised machine learning and provincial panel data.

Public attitudes toward consensual same-sex relations are crucial to lesbians' and gay men's rights and society's well-being, but research addressing this topic in China is limited. We comprehensively explored the current status and predictors of Weibo users' attitudes toward individuals who are lesbian or gay (IWLG) at the provincial level in the Chinese mainland. Natural language processing and machine learning techniques were incorporated to analyze 1,934,008 Weibo posts from January 1, 2010, to December 31, 2020, to evaluate Weibo users' expressed attitudes toward IWLG in 31 provinces in the Chinese mainland guided by the ABC Model of attitude. Although the general attitudes, feelings, and support for the rights of Weibo users toward IWLG among different provinces were relatively positive, knowledge about IWLG was noticeably inaccurate. Economic development and educational level positively predicted certain aspects of attitudes at the provincial level. Weibo users from different provinces are generally supportive and accepting of people who are gay and the rights of the gay community. However, considerable misconceptions and inaccurate knowledge of IWLG surfaced in Weibo users' posts. Economic development and educational level were important predictors of specific attitudes toward IWLG at the provincial level. Increased efforts to address the unbalanced and insufficient development between different provinces could help reduce the public's prejudice, stigma, and discrimination toward IWLG. Policies that facilitate greater implementation of Comprehensive Sexuality Education sequentially and effectively are suggested as well.

Integrative approach for classifying male tumors based on DNA methylation 450K data.

Malignancies such as bladder urothelial carcinoma, colon adenocarcinoma, liver hepatocellular carcinoma, lung adenocarcinoma and prostate adenocarcinoma significantly impact men's well-being. Accurate cancer classification is vital in determining treatment strategies and improving patient prognosis. This study introduced an innovative method that utilizes gene selection from high-dimensional datasets to enhance the performance of the male tumor classification algorithm. The method assesses the reliability of DNA methylation data to distinguish the five most prevalent types of male cancers from normal tissues by employing DNA methylation 450K data obtained from The Cancer Genome Atlas (TCGA) database. First, the chi-square test is used for dimensionality reduction and second, L1 penalized logistic regression is used for feature selection. Furthermore, the stacking ensemble learning technique was employed to integrate seven common multiclassification models. Experimental results demonstrated that the ensemble learning model utilizing multiple classification models outperformed any base classification model. The proposed ensemble model achieved an astonishing overall accuracy (ACC) of 99.2% in independent testing data. Moreover, it may present novel ideas and pathways for the early detection and treatment of future diseases.