Medication Adherence Self-Efficacy Scale Research Articles

The Effect of Education and Monitoring via Tele-Nursing to Elderly Cancer Patients Using Oral Anticancer Agents on Self-efficacy and Medication Adherence: A Randomized Controlled Trial

ObjectivesThis study was conducted as a randomized controlled trial to determine the effect of the education and monitoring provided via tele-nursing to elderly cancer patients using oral anticancer agents on their medication treatment adherence self-efficacy and medication adherence. MethodsThe sample of the study consisted of 60 elderly cancer patients who presented to the oncology outpatient clinics of a medical faculty hospital in Turkey. An Elderly Information Form, the Oral Chemotherapy Adherence Scale, the Medication Adherence Self-Efficacy Scale, a Tele-nursing Evaluation Form, and a Telephone Monitoring Form were used to collect data. Patients in the intervention group were sent text messages and educational videos via WhatsApp® for the first four weeks, and after the fifth week, they were monitored by phone for eight weeks. Data collection tools were applied to the control and intervention groups at weeks 1, 8, and 12. Independent samples t-test, Repeated measurements analysis of variance chi-square test, and Pearson correlation test were used to analyze the data. ResultsIn the study, while there was no significant difference between the mean scores of the intervention and control groups on the pretest application of the Oral Chemotherapy Adherence Scale and the Medication Adherence Self-Efficacy Scale (p > .05), a significant difference was found between the mean posttest scores of the groups (p < .05). ConclusionsIn this study, it was determined that the education and monitoring provided to elderly cancer patients via tele-nursing positively affected their self-efficacy and medication adherence. Implications for nursing practiceIn line with the research results, it is recommended that nurses use tele-nursing applications in the care of elderly cancer patients using oral anticancer agents.

Evaluation of clinical adherence measures for oral oncolytics: A systematic review.

e23130 Background: Despite the critical importance of adherence monitoring for oral oncolytics, there are no standard measures for clinical practice. Methods: We conducted a systematic review using 4 databases aiming to characterize validated adherence monitoring tools utilized in either pre-implementation or evaluation of clinical programs. Various Medical Subject Headings (MeSH) and other search terms related to cancer, oral oncolytics, adherence, metrics, and outcomes were included. Measures used only for research (outside of clinical use) were excluded. Two independent reviewers screened articles with a third reviewer resolving discrepancies. Data extraction and quality assessments concluded the review. Results: Out of 751 screened articles, 73 proceeded to full-text review, with 6 selected for data extraction and quality assessment (Table 1). Two studies focused on the Morisky Medication Adherence Scale-8 (MMAS-8) tool, while others examined Michigan Oncology Quality Consortium Patient Reported Outcome Measure (MOQC PROM), 6-Item Girerd Scale, Medication Adherence Self-Efficacy Scale (MASES), and EXPeriencia con y ADherencia a AntiNEoplasicos Orales (EXPAD-ANEO). Among the five tools, MASES featured the most questions (24). All tools were implemented by healthcare professionals. Girerd and MASES were used specifically in hematologic and solid tumor populations respectively, whereas the remaining tools were applied in both cancer types. MMAS-8 and MASES were employed to evaluate current clinical programs, while MOQC PROM, Girerd, and EXPAD-ANEO were used during pre-implementation for future programs. Common biases from studies included limited generalizability, patient self-reported adherence credibility, and variability in patient baseline characteristics. Conclusions: Our findings highlight the paucity of validated adherence monitoring tools in clinical practice. The five tools discussed above exhibit potential in measuring adherence in a clinical setting; however, small sample size and short duration limit generalizability. Further investigation of new and existing tools in broader settings is needed. [Table: see text]

The Effect of Training and Phone Counselling Provided to Hypertension Patients on their Medication Adherence and Rational Drug Use: A Single-blind Randomised Controlled Trial

Background: Hypertension is a chronic disease characterised by high blood pressure, which is an important public health problem that causes serious complications. It is very important to provide training and remote telephone counselling to patients for them to comply with the drug treatment of hypertension disease and to comply with the principles of rational drug use. Aim: This study aimed to define the effect of training and phone counselling provided to hypertension patients on their medication adherence and rational drug use. Methods: The study was conducted randomised controlled as a single-blind experimental study between July 2021 and June 2022. The study universe consisted of hypertension patients admitted to hospital, and the sample consisted of 92 patients. The block randomisation method was used. The study data were collected using a Patient Identification Form; the Medication Adherence Self-efficacy Scale; and the Rational Drug Use Scale. The experimental group received training once, in addition to a total of four phone counsellings (week 2-4-8-12). Results: According to the group-by-time interaction of control/experimental group patients, a statistical difference was found between the median scores of the Medication Adherence Self-efficacy Scale and the Rational Drug Use Scale (p&lt;0.001). The pre-test median of the Medication Adherence Self-efficacy Scale of the experimental group patients was 30.00, and the post-test median was 46.00. The pre-test median of the Rational Drug Use Scale of the experimental group patients was 43.00, and the post-test median was 68.00. Conclusion: In the study, it was determined that the application of education and telephone counselling to hypertension patients increased patients’ medication compliance and rational drug use. In systolic-diastolic blood pressure levels, which are critical for hypertension patients, it was determined that the application of education and telephone counselling significantly decreased the blood pressure of patients.

Development of an EKA application to help tuberculosis patients improve medication adherence and self efficacy

Tuberculosis treatment is carried out daily for a long time, causing boredom with taking medication and reducing medication adherence. It results in drug resistance and more prolonged treatment. In response to the situation, this study developed an android-based application called the education, calendar, and medication alarm (EKA) app to improve medication adherence and self-efficacy of tuberculosis patients. Research and development with four steps: evaluation of health education, medication adherence, and self-efficacy; application development; feasibility test; and application socialization. The sample in this study was 38 respondents. This study also uses morisky medication adherence scale (MMAS-8), self-efficacy, and system usability scale (SUS) questionnaires and evaluation sheets to collect the data. Data analysis was done descriptively. The outcomes of the application feasibility test showed that the EKA application received an acceptable value of 81.5 based on acceptance, B value (81.5) based on value scale, an excellent value (81.5) based on adjective rating, and good score (81.5) based on percentile. Socialization on the use of the application goes well, and the patient gets a good understanding and can use the EKA application easily. It proves that the android-based EKA application tested using the SUS questionnaire can be used as a medium for health education and supports medication adherence and self-efficacy.

Randomized Control Trial of the Impact of Patient Decision Aid Developed for Chinese Primary Open-Angle Glaucoma Patients

Introduction: Patient decision aid (PDA) is a tool to prompt shared decision-making. The aim of this study was to evaluate the impact of a PDA on Chinese primary open-angle glaucoma patients. Methods: All subjects were randomized into control and PDA group. The questionnaires, including 1) glaucoma knowledge; 2) 8-item Morisky medication adherence scale (MMAS-8); 3) 10-item glaucoma medication adherence self-efficacy scale (GMASES-10); and 4) 16-item decision conflict scale (DCS), were evaluated at baseline, 3- and 6-month follow-up. Results: Totally, 156 subjects participated in this study, including 77 in the control group and 79 in the PDA group. Compared to the control group, PDA group showed around 1 point more improvement in disease knowledge at both 3 and 6 months (both p < 0.05), 2.5 (95% CI: [1.0, 4.1]) and 1.9 (95% CI: [0.2, 3.7]) points more improvement in GMASES-10 at 3 and 6 months, respectively, and reduction in DCS by 8.8 (95% CI: [4.6, 12.9]) points more at 3 months and 13.5 (95% CI: [8.9, 18.0]) points more at 6 months. No difference was detected in MMAS-8. Conclusion: PDA led to improvement in disease knowledge and self-confidence in medication adherence and reduced decision conflict compared to control group for at least 6 months.

Abstract 9445: Using Latent Class Analysis to Identify Antihypertensive Adherence Trajectories: The BETTER-BP Trial

Introduction: Adherence to antihypertensive medications remains low in many patients. In this context, the BETTER-BP randomized trial was designed to test whether providing small financial rewards for medication adherence with a text message-based lottery system improves adherence and lowers blood pressure. In this preliminary analysis we characterized adherence trends from baseline to 6 months in BETTER-BP through 12/2021. Methods: Participants were recruited from two safety-net clinics in New York City (Bellevue Hospital and NYU-Brooklyn FHC). There were 101 participants with six months of complete adherence data. Mean weekly adherence was recorded through an Adheretech electronic monitoring device. Latent class mixed methods analysis was used to determine categorizable adherence trajectory trends over six months. We then investigated factors (age, sex, insurance status, comorbidity burden, depression, self-efficacy) that predicted category membership. The analysis remained blinded to treatment arm given that full enrollment was not yet complete. Results: Three distinct adherence trajectories were determined: (1) High, persistent adherence (n=53), (2) Gradually declining adherence (n=33), and (3) Early declining non-adherence (n=15). In a multivariable analysis, only self-efficacy (based on the medication adherence self-efficacy scale [MASES]) had a significant (p=0.02) association with adherence, with mean MASES scores of 81.4, 76.3 and 72.1 for clusters (1), (2) and (3) respectively. Conclusions: In this preliminary analysis, we found that the majority of participants had high persistent adherence, and that those with high self-efficacy were more likely to be members of this category. These results will need to be confirmed at trial completion (target sample N = 435). Figure 1. Mean participant adherence trajectory clusters over six months.

The influence of the pandemic on fear of contagion, blood pressure management and adherence to medication in hypertensive older adults in Turkey.

The study was conducted to identify the impact of the pandemic on hypertensive older people’s COVID-19 fear, blood pressure control, and medication adherence. In this descriptive, correlational study, mean medication adherence was taken as 45.6 ± 6.06% based on the literature, with a 5% margin of error, and the sample size was determined as 292 with 95% confidence interval and 80% power. Data were collected from 419 older individuals using a sociodemographic information form, an infodemic-related questionnaire, Fear of COVID-19 Scale, and Medication Adherence Self-Efficacy Scale via Google Forms. The data were analyzed using IBM SPSS Statistics 23 software via independent sample t test, one-way variance analysis, χ2 analysis, and the Pearson correlation coefficient. It was found that, rather than avoiding hospitals during a pandemic, one out of two older people had had their blood pressure checked. One out of every five had abnormal/uncontrolled blood pressure during the pandemic. The infodemic was found to increase concern levels, and those with high fear scores had abnormal/uncontrolled levels of blood pressure. Moreover, a low-level positive correlation was found between medication adherence and the level of fear of COVID-19. As the pandemic continues, older people with hypertension need support in terms of monitoring blood pressure and medication adherence as well as increased awareness about the pandemic.

The effect of nurse-led telephone support on adherence to blood pressure control and drug treatment in individuals with primary hypertension: A randomized controlled study.

The aim of this study was to evaluate the effect of telephone monitoring, in combination with texts, on medication adherence and blood pressure (BP) control in primary hypertension. Data were collected from August to December 2016. Seventy-seven adults were randomized to the intervention and control groups. A 12-week intervention consisted of regular text messages and phone calls. The control group received usual hypertension care. The outcomes were evaluated with blood pressure measurement and medication adherence self-efficacy scale short form. Medication adherence in Week 12 was found to be significantly higher in the intervention group than in the control group. Mean systolic and diastolic BP levels in Weeks 4, 8 and 12 were statistically significantly lower in the intervention group than in the control group (p < 0.05). Using text messaging and nurse-led telephone monitoring improved adherence and BP control in adults with hypertensive in primary care.

The Effect of Educational Follow-Up with the Motivational Interview Technique on Self-Efficacy and Drug Adherence in Cancer Patients Using Oral Chemotherapy Treatment: A Randomized Controlled Trial.

This study aimed to determine the effect of educational follow-up with the motivational interview technique on drug adherence and self-efficacy in patients with cancer using at least one oral chemotherapy drug. A total of 80 patients with cancer were randomly allocated to the intervention group or the control group. Educational follow-up with the motivational interview technique was applied to the patients with phone calls during weeks 1, 3, 6, and 9. Patients in the intervention and control groups were evaluated during both the first interview and at week 12 using a questionnaire, the medication adherence self-efficacy scale (MASES), and oral chemotherapy adherence scale (OCAS). At the end of the study, the level of drug adherence and self-efficacy of patients who received educational follow-up with the motivational interview technique by phone call increased significantly (P < .001). Additionally, the level of drug self-efficacy of patients increased (P < .001). This study emphasizes treatment compliance problems of patients with cancer using oral chemotherapy. Designed with communication techniques that will be added to our counseling process, interventions can allow nurses to use their time effectively.

Factors Associated with Antihypertensive Medication Adherence among Diabetic Patients with Coexisting Hypertension in a Tertiary Care Centre from a Low Middle Income South Asian Country

Introduction: Poor medication adherence is a known preventable factor which can adversely affect desired achievable blood pressure (BP) target. Strict control of blood pressure is essential among patients who have diabetes and hypertension (HT) in order to prevent complications. This is the first study conducted among 371diabetic patients with co-existing HT to examine the antihypertensive medication adherence in Sri Lanka to date. Materials and Methods: This cross-sectional study was done in the general medical clinics of Jaffna Teaching Hospital from October 2019 to November 2019. Results: The majority (66.6%) of the patients were female. Mean age of the participants was 60.93 ± 9.77. The total mean score for modified MASES (Medication Adherence Self Efficacy Scale) was 48.1 ± 3.81. A negative correlation was noted between MASES scores and systolic (r= -0.033) and diastolic (r=- 0.083) blood pressure. Median score 49 was used to classify the patients into optimal or suboptimal adherence to antihypertensive medication. A significant percentage (43.4%CI: 38.4-48.5) of research participants were sub optimally adhered to antihypertensive medication. Among the associated factors explored, gender (P-0.007), low-income (P-0.002) and employed people (P-0.046) showed significant association with poor adherence. However, the number of co-morbidities (P-0.335), number of medications (P-0.454), duration of hypertension (P-0.440), and frequency of clinical visits (P-0.373) were not significantly associated with anti-hypertensive medication adherence. Conclusion: This finding has an implication in clinical practice to improve the quality of care. Professionals should give consideration to above socio-demographic factors (gender, income, and occupation) before prescribing appropriate medication and its dosing schedule for hypertension.

The effect of loneliness and perceived social support on medication adherence self-efficacy in hypertensive patients: An example of Turkey

This study was conducted to investigate the effect of loneliness and perceived social support on medication adherence self-efficacy in hypertensive patients. This descriptive cross-sectional study was conducted between March and June 2015 at 5 Family Health Centers in central Erzincan in eastern Turkey. The data were collected through face-to-face interviews using a descriptive questionnaire, the UCLA Loneliness Scale, the Multidimensional Scale of Perceived Social Support, and the Medication Adherence Self-Efficacy Scale Short Form. The mean score obtained from the UCLA Loneliness Scale was 38.35±9.85, from the Multidimensional Scale of Perceived Social Support 64.10±18.31, and from the Medication Adherence Self-Efficacy Scale 40.27±11.97. The mean UCLA Loneliness Scale score was found to have a low negative correlation with the mean Medication Adherence Self-Efficacy Scale score and a highly significant negative correlation with the mean Multidimensional Scale of Perceived Social Support score (P<.001). There was also a very low positive significant correlation between the mean scores of the Multidimensional Scale of Perceived Social Support and the Medication Adherence Self-Efficacy Scale (P<.001). This study revealed that individuals with hypertension perceived a moderate level of loneliness, and their perceived social support and medication adherence self-efficacy were higher than the moderate level. Perceived loneliness and perceived social support were significant indicators of perceived medication adherence self-efficacy. Therefore, effective consultancy services should be provided to hypertensive patients to increase their social support and to make positive changes in their perceived loneliness so that their perceived medication adherence self-efficacy can be improved.

Motivasyonel Görüşmenin Hipertansif Bireylerin Yaşam Tarzı, Vücut Kitle İndeksi, Kan Basıncı, Özyeterlilik Algısı ve İlaç Tedavisi Uyumuna Etkisi

Aim: This study aims to analyze the effect of motivational interviewing on the lifestyle, blood pressure, body mass index, selfefficacy perception, and medication adherence of hypertensive individuals.Material and Methods: This study was conducted with hypertensive individuals between the ages of 25 and 45 registered in seven Family Health Centers in Akşehir, Konya. Inclusion in the present study was voluntary, and 80 people who agreed to participate were randomized into two groups as experimental and control groups. However, the present study was completed with 75 participants. Both groups were administered the pre-test, then the experimental group was visited for a total of 5 times: four visits at three-week intervals and one visit after one month. In each visit, a 30 to 45 minute individual motivational interviewing was carried out. The study was completed by administering the last-test to both groups. The study was conducted between February 6 and June 24, 2014, and the data were analyzed using the SPSS 17.0 package.Results: Statistically significant differences were found between the pre-test and last-test scores of the experimental group in terms of Blood Pressure, Body Mass Index, the Medication Adherence SelfEfficacy Scale, and the General Self-Efficacy Scale.Conclusion: Motivational interviewing can be used in ensuring healthy nutrition and regulation of exercise level and blood pressure of hypertensive individuals, and in increasing their selfefficacy and treatment adherence.

&lt;p&gt;Impact of multimodal interventions on medication nonadherence among elderly hypertensives: a randomized controlled study&lt;/p&gt;

Purpose: The study was conducted to investigate the effects of multimodal interventions on medication nonadherence, quality of life (QoL), hypertension (HTN), self-efficacy, and clinical outcome in terms of blood pressure (BP) among elderly people with HTN.Methods: An experimental design using a randomized controlled trial was adopted (N=80+80). The experimental group received multimodal interventions and the control group received routine care. Both groups were followed up at baseline and at 3 and 6 months. The data collection tools of demographic and clinical proforma, structured knowledge questionnaire on HTN (r=0.84), Revised Medication Adherence Self-Efficacy Scale (r=0.94), Morisky Medication Adherence Scale (r=0.83), World Health Organization Quality of Life-BREF scale (r=0.87), and digital BP apparatus were used. Necessary administrative permission was obtained for the study.Results: The study results proved that nurse-led multimodal interventions led to an improvement in medication adherence [F(1.75,214.30)=774.18, p<0.001], knowledge on HTN [F(2,244)=43.83, p<0.001], and self-efficacy [F(1,122)=3.99, p=0.04] of elderly people on antihypertensives over a period of 6 months. Overall QoL did not exhibit any statistically significant improvement, and no statistically significant reductions in the systolic BP (SBP) and diastolic BP (DBP) scores were obtained (p>0.05) in the experimental group over a period of 6 months. However, the clinical significance of multimodal interventions for improvements in medication adherence, QoL, knowledge on HTN, and self-efficacy was more favorable compared with the reduction in SBP and DBP scores.Conclusion: Nurses play a crucial role in improving medication adherence among elderly people with HTN.Trial details: Ethical clearance was obtained (IEC no. KH IEC 253/2012) from the Institutional Ethical Committee of Manipal University, Manipal, and the study was conducted in accordance with the Declaration of Helsinki. The study is registered under Clinical Trials Registry of India (CTRI/2017/04/008405). Informed consent was obtained from participants, and the confidentiality of information was assured.

Effect of social support on the treatment adherence of hypertension patients

This descriptive study was conducted to determine the effect of social support on drug treatment adherence in patients with hypertension. The sample of this study consisted of 259 patients who met the research criteria, agreed to participate in the research, and admitted to the cardiology clinic of a university hospital in Turkey between January and June 2017. Data were collected by "Patient Information Form", "Adherence to Drug Treatment Self-Efficacy Scale", and "Multidimensional Perceived Social Support Scale". It was determined that 48.3% of the patients participating in the study were in the 61-75 age group, 58.7% were female, 91.9% were married, and 66.4% were living in the city. It was also found that 71% of the patients had at least one relative or person with hypertension in the family, 79.2% were using at least one blood pressure medication, 61% adhered to his/her diet, and 72.2% adhered to the disease. The average score of the Medication Adherence Self-Efficacy Scale was calculated as 64.24±16.89, whereas the total score average of the Multidimensional Perceived Social Support Scale was calculated as 53.74±23.30. Besides, a statistically significant positive correlation was found among Medication Adherence Self-Efficacy Scale score average, Multidimensional Perceived Social Support Scale total score, and all subgroup score averages (P=.000).In conclusion, in this study, treatment adherence and social support levels of the patients were found to be substantially good; besides, adherence to drug treatment was found to increase positively as the social support of patients with hypertension increase.

Evaluation of medication adherence in hypertensive patients and influential factors.

Objective:This study aims to evaluate medication adherence in hypertensive patients and to identify the influential factors.Methods:This descriptive, cross-sectional study included a total of 147 hypertensive patients who were admitted to Akdogan Health Center between December 2016 and February 2017. The Descriptive Data Form and Medication Adherence Self-Efficacy Scale were used as the data collection tools.Results:The mean Medication Adherence Self-Efficacy Scale score was found to be 70.29 ± 8.52. Age, duration of HT, the frequency of follow-up visit for HT, the status of taking medication regularly, the frequency of blood pressure measurement and the status of alternative method use were found to be effective in medication adherence.Conclusions:Our study results suggest that medication adherence is good in patients with hypertension (HT). Factors which are effective in medication adherence should be taken into consideration, when evaluating the medication adherence in patients with HT.

Hypertensive Individuals’ Use of Complementary Health Approaches and its Effect on Adherence with Antihypertensive Medication Treatment

Objective: This study was conducted with the aim of determining the uses of complementary health approaches (CHA) in patients with hypertension and its effect on adherence with antihypertensive medication. Method: This descriptive study was conducted at Karaağaç Family Health Center located in the city center of Erzincan. Between June 2013 and December 2013, the individuals who consulted to the center for some reason and received antihypertensive treatment, were included. The data were collected through face-to-face interviews using a questionnaire containing open- and closed-ended questions and the Medication Adherence Self-Efficacy Scale Short Form (MASES-SF). The blood pressure, height and weight measurements were performed. Results: It was determined that 42.7% of the hypertensive patients were using natural produces for nutrition as part of their CHA, the use of CHA was higher in those under the age of 65 and in women (p<0.05) and using CHA had no significant effect on blood pressure control or the mean MASES-SF score (p>0.05). Medication adherence of the patients was on a good level. The mean MASES-SF scores of the patients whose blood pressure was under control were found higher (p<0.001) than those were not under control. Conclusion: It was concluded that approximately one of the two hypertensive patients was using nutrient-based natural products as an adjunctive health care supplement for antihypertensive treatment, however this did not have any impacts on blood pressure control and changing medication adherence. Blood pressures of t he patients with a high level of adherence to their antihypertensive therapies have been under control. The healthcare professionals who work at primary care institutions should be aware of that they are advised to use some complementary practices besides medical methods for the purpose of controlling the blood pressure of hypertensive patients. Amaç : Bu araştırma hipertansiyon hastalarının tamamlayıcı sağlık yaklaşımı (TSY) kullanımları ve bunun antihipertansif ilaç tedavisi uyumuna etkisini belirlemek amacı ile yapıldı. Yöntem : Tanımlayıcı özellikteki bu araştırma Erzincan il merkezinde bulunan Karaağaç Aile Sağlığı Merkezinde yürütüldü. Haziran-Aralık 2013 tarihleri arasında merkeze herhangi bir nedenle başvuran ve antihipertansif tedavi alan bireyler araştırmaya alındı. Veriler açık ve kapalı uçlu soru formu ve İlaç Tedavisine Bağlılık/Uyum Öz-Etkililik Ölçeği Kısa Formu (İBÖS-KF) kullanılarak yüz yüze görüşme yöntemi ile toplandı. Kan basıncı, boy ve kilo ölçümü yapıldı. Bulgular: Hipertansiflerin % 42,7’sinin TSY olarak besin temelli doğal ürünler kullandığı, TSY kullanımının 65 yaş altındakilerde ve kadınlarda daha fazla olduğu (p < 0,05), TSY kullanımının kan basıncı kontrolü ve İBÖS-KF ölçek puan ortalaması üzerinde önemli bir etkisinin olmadığı belirlendi (p > 0,05). Hastaların ilaç uyumu iyi düzeydeydi. Kan basıncı kontrol altında olanların İBÖS-KF ortalamaları olmayanlardan daha yüksek bulundu (p < 0,001). Sonuç: Yaklaşık olarak her iki hipertansif hastadan birisinin antihipertansif tedaviye ek tamamlayıcı sağlık yaklaşımı olarak besin temelli doğal ürünler kullandığı ancak bu durumun kan basıncı kontrolüne ve ilaç uyumlarına bir etkisinin olmadığı sonucuna ulaşılmıştır. Antihipertansif tedavi uyumları yüksek olan hastaların kan basınçları kontrol altındadır. Birinci basamak sağlık kurumlarında çalışan sağlık profesyonellerinin hipertansif hastalarının kan basıncı kontrolü amacıyla tıbbi yöntemler dışında bazı tamamlayıcı uygulamaları da sorgulamaları önerilebilir.

The effect of structured education to patients receiving oral agents for cancer treatment on medication adherence and self-efficacy

Objective:This study was conducted to examine the effect of structured education on medication adherence and self-efficacy through the use of the MASCC Oral Agent Teaching Tool (MOATT) for patients receiving oral agents for cancer treatment.Methods:This quasi-experimental study has been conducted at two hospitals; 41 patients were included in the study. Data were obtained using a questionnaire, medication adherence self-efficacy scale (MASES), memorial symptom assessment scale, and a follow-up form (diary). Patients were educated through the use of the MOATT at a scheduled time; drug-specific information was provided along with a treatment scheme and follow-up diary. Phone interviews were completed 1 and 2 weeks after the educational session. At the next treatment cycle, the patients completed the same questionnaires.Results:Majority of the patients were receiving capecitabine (90.2%; n = 37) as an oral agent for breast (51.2%; n = 21) and stomach cancer (24.6%; n = 10) treatment. About 90.2% of patients (n = 37) stated that they did not forget to take their medication and experienced medication-related side effects (78%; n = 32). The total score of MASES was increased after the education (66.39 vs. 71.04, P < 0.05).Conclusions:It was shown that individual education with the MOATT and follow-up for patients receiving oral agents for cancer treatment increased patient medication adherence self-efficacy.

Abstract P265: Sex Differences in the Mediation of Relationship Between Depression and Nonadherence by Self-Efficacy

Purpose: We tested for sex differences in how self-efficacy explains the relationship between incident depressive symptoms and incident low adherence using data from the Cohort Study of Medication Adherence among Older Adults (CoSMO). Methods: A telephone survey was administered to hypertensive older adults three times at yearly intervals. Depressive symptoms were defined as a score ≥16 on the Center for Epidemiologic Studies Depression Scale. Low adherence was defined as a score &lt;6 on the 8-item Morisky Medication Adherence Scale. Item scores on the 26-item Medication Adherence Self-Efficacy Scale were summed to create a self-efficacy score. Analysis was restricted to those without low adherence or depressive symptoms at baseline (n=1478). Mediation of the relationship between incident depressive symptoms and incident low adherence between baseline and first follow-up by self-efficacy at first follow-up was assessed using Baron &amp; Kenny’s procedures, modified to test for sex differences. Results: The sample was 58% female and 28% black, with a mean age of 75.2 years. The incidence of depressive symptoms and low adherence were 7.7% and 7.2%, respectively. The indirect effect (IE) – the portion of the effect of incident depressive symptoms on incident low adherence that is explained by self-efficacy - was significant for women (IE=0.029 95% CI 0.005, 0.068), such that 34.1% of the total effect of incident depressive symptoms on incident low adherence was explained by self-efficacy. The IE for women was significantly different from that for men (IE=-0.003 95% CI -0.019, 0.006). The direct effect of incident depressive symptoms on incident low adherence – the portion of the effect that is not explained by self-efficacy – was significantly different for women and men (direct effect (DE)=0.056 95% CI -0.082, 0.155 and DE=0.205 95% CI 0.060, 0.323, respectively). Conclusions: Self-efficacy explains some of the relationship between incident depressive symptoms and incident low adherence for women, but not for men.

Counseling Intervention for Enhancing Physical Health and Subjective Well-Being Among Elderly With Chronic Illness at Geriatric Homes

Objective: The aim of this study was to determine the efficacy of counseling intervention in improving physical health and subjective well-being among elderly with chronic illness at geriatric homes. The study was conduct in four geriatric homes affiliated with social solidarity agency .The sample of this study 102 elderly individuals . data were collected through an interview questionnaire sheet , KATZ Activities of Daily Living scale, Personal Health Inventory, The Modified Subjective Well-Being Scale and Medication Adherence Self-Efficacy Scale (MASES).The result of the present study showed a highest proportion of old age have Independence level of Daily activity . there was a significant improvement in a neutral zone of health behavior and subjective well –being after implementing counseling sessions . The present study recommended that future research to assesses an impact of health-promoting life-style behaviors on life satisfaction among elderly individual with chronic illness at geriatric homes.

Development and Psychometric Testing of the Turkish-Version Oral Chemotherapy Adherence Scale.

To ensure the quality of patient care, the bioavailability of drugs, and the success of the treatment, it is imperative that nurses evaluate the adherence of patients to pharmaceutical treatments using standard measurement tools that are integrated into the treatment process. No scale that uses psychometric analyses to evaluate this adherence in patients who are on oral chemotherapy is currently available. This study developed and tested the validity and reliability of a Turkish version of the standardized Oral Chemotherapy AdherenceScale (OCAS), a tool that may be used by healthcare personnel to better evaluate patient adherence to their therapies. We developed and examined the validity and reliability of the OCAS using a sample of 306 patients with cancer who were receiving oral chemotherapy. A literature review was conducted to generate the items. An expert panel evaluated content validity; preimplementation was used to evaluate face validity, factor analysis was used to evaluate construct validity, and criterion validity was evaluated using the Medication Adherence Self-Efficacy Scale. The Cronbach's alpha calculated for OCAS (19 items) was .738. A highly significant and positive correlation was observed between the test-retest scores of the participants. A positive significant correlation was observed between the total scores of the participants obtained from OCAS and Medication Adherence Self-Efficacy Scale. As a result of the factor analysis performed for the construct validity of the scale, three factors were defined that accounted for approximately 43% of the total variance. The OCAS has acceptable psychometric properties and is appropriate for use in research and clinical practice settings to evaluate patient adherence to their therapies.