Medication Adherence In Hypertensive Patients Research Articles

Assessment of Medication Adherence in Hypertensive Patients among Warangal Population

Background: Hypertension is the most common disease in India where 1 in 4 people suffering with it. In order to achieve the intended therapeutic outcomes, medication adherence is essential. Patients with hypertension must adhere to their disease by taking their prescriptions on time, following their diet, and making other lifestyle modifications. This study aims to assess medication adherence in Warangal population among hypertensive patients with comorbidities, social habits, medication use etc. Aims: The aim of the study is to assess the level of medication adherence and to investigate predictors of medication adherence and controlled hypertension in patients and to identify the factors enhancing medication adherence. The secondary aim is to describe the extent and type of medication used in patient population in Warangal. Study Design: An Observational, retrospective and cross - sectional study was employed to assess the predictors and level of medication adherence in hypertensive patients. Place and Duration of Study: Department of Cardiology, Sri Sri Cardiac Centre and Bhageerath Cardiac Care Centre, Hanamkonda, Warangal. The study was conducted from October 2022 to April 2023 for about a duration of 7 months. Methodology: This study includes 300 Hypertensive patients (Male - 169, Female 131) of age range between 20-90 years with various comorbidities like diabetes mellitus, coronary artery disease, hypothyroidism, dyslipidemia, COPD. We also included various sociodemographic factors like Gender, Age, Literacy, Income status, Alcohol consumption, Smoking status, Marital status, Controlled and Uncontrolled hypertension, usage of various drugs and Duration of hypertension. We observed Medication Adherence by using MMAS 8 scale. Results: Low levels of medication adherence among female patients (41%), educated patients (58%) compared to other groups because of awareness about their condition. Low adherence is noted in patients with low-income status ( 9.6% ), High adherence in nonsmokers (73.3%) and non-alcoholic (60.6%) compared to smokers (10.6%) and alcoholics (12.6%) and high adherence is reported in married (85%) category as compared to unmarried (2.6%), Patients with low comorbidities reported high adherence compared to patients with low comorbidities. High medication adherence is reported in uncontrolled blood pressure (50.3%) and in patients with \(\le\) year (24.6%) and 2-6 years (28%) of duration of hypertension. High adherence is noted with 2 combination therapy (23.6%), most of the participants are adherent to Telmisartan+ Metoprolol (25.2%) followed by Telmisartan+ hydrochlorothiazide (19.3%). According to MMAS-8 scale most of the patients reported (Q1) and (Q6), 91.3% of our study population were adherent to their medication, 7% were moderately adherent and 1.6% were low adherent to their medication. Conclusion: 91.3% of Medication adherence is noted in hypertensive patients in Warangal population. 8.6% of Medication Non-Adherence is noted and various factors for nonadherence were reported by patients. However various methods and apps should be developed to overcome the Medication Non-Adherence.

Description of Factors that Influence Medication Compliance in Hypertension Patients at the Separi 3 Kutai Kartanegara Health Center

Hypertension is a lifelong disease that cannot be permanently cured but can only be controlled by controlling blood pressure by managing a healthy lifestyle and taking recommended antihypertensive drugs. Purpose: this study is to describe the factors of knowledge, family support, and access to health facilities that influence medication adherence in hypertensive patients at the Separi Health Center. Methods: this study used a descriptive research design with a cross sectional approach. The sampling technique used is probability sampling technique with proportional stratified random sampling method with a total sample of 84 respondents. Results: the study showed that 82.1% of patients did not adhere to taking medication, and 17.9% of patients adhered to taking medication. Patients with less knowledge 31.0% and patients with good knowledge 69.0%. Patients with poor family support 56.0% and patients with good family support 44.0%. Patients with poor access to health services 46.4% and patients with good access to health services 53.6%. Conclusion: the results of the study show that despite having good knowledge, family support, and access to health services, most patients do not adhere to taking medication. Suggestions for existing health services are expected to improve service quality and provide information and education to people with hypertension.

Knowledge, Awareness, and Determinants of Medication Adherence in Hypertensive Patients: A Hospital-Based Cross-sectional Study in North India

ABSTRACT Background: Knowledge and awareness studies reveal the basic information of the community and the misconceptions in relation to practices of a disease. The identification of such factors is important as they directly influence the health care-related interventions. Hypertension is one of the emerging noncommunicable diseases (NCDs) globally. So, we conducted this study to assess the status of our community regarding hypertension. Materials and Methods: The study was conducted on 300 hypertensive patients to assess the knowledge and awareness by a hypertension fact questionnaire. Medication adherence was assessed in the same group of patients by Hill–Bone scale—a uniform scale used worldwide. Results: Our study revealed a greater number of females with hypertension as compared to males and a maximum number of patients being in the age-group of 61–70 years and belonging to rural areas. Most of the patients had a secondary education as a highest educational qualification with only 10% of patients being postgraduates. A fair number of patients had a good knowledge and awareness about their disease, and most of the respondents accounted forgetfulness as a main reason for nonadherence to therapy over other reasons. Conclusion: Our population has good knowledge and awareness about their disease despite not having very good educational qualifications, and we need to strengthen our healthcare programs for even more greater dissemination of information.

Barriers and Facilitators of Medication Adherence in Hypertension Patients: A Meta-Integration of Qualitative Research.

The aim of this qualitative systematic review is to analyze the barriers and facilitators to the uptake of antihypertensive medication in hypertensive patients. The databases of PubMed, Embase, Web of Science, CINAHL, Cochrane Library, MEDLINE, China National Knowledge Infrastructure, Wanfang, VIP, and Chinese Biomedical were searched from inception to June 2023. The studies were screened, extracted, and assessed independently by two researchers. Previously, the researchers used the Joanna Briggs Institute Critical Appraisal Checklist for Qualitative Research to assess the quality of the included studies. A total of 27 studies were considered, resulting in two combined findings: a good level of knowledge, belief, and behavior and adequate social support were facilitators of medication adherence in hypertensive patients. In contrast, lack of medication literacy, difficulty adapting to roles, reduced sense of benefit from treatment, limited access to healthcare resources, and unintentional nonadherence were barriers. Medication adherence in hypertensive patients remains a challenge to be addressed. Future research should explore how complex interventions using a combination of evidence-based strategies and targeting multiple adherence behaviors (eg, long-term adherence to medication) are effective in improving medication adherence.

Unveiling the Nexus: Depressive Symptoms and Medication Adherence in Hypertensive Patients' Self-care: A Systematic Review.

Hypertension, a significant public health concern, is frequently linked to emotional disorders like depression. Research shows a reciprocal link between depression and hypertension, potentially influencing patients' adherence to self-care routines. This systematic review aimed to examine the association between depressive symptoms and aspects of self-care, with a focus on medication adherence in individuals diagnosed with hypertension. Following PRISMA guidelines, a systematic review was conducted by searching PubMed, PsycINFO and Scopus until March 17, 2023. The included studies involved quantitative primary research conducted in English, focusing on adults (≥18 years) diagnosed with hypertension and experiencing depressive symptoms. Observational studies were assessed using the Newcastle-Ottawa Scale, and randomized controlled trials were evaluated using the revised Cochrane Risk of Bias Tool (RoB 2.0). Due to the great diversity of these studies, a narrative synthesis of the results was undertaken. Results: A total of 18 studies involving 6,131 people with hypertension, that met our eligibility criteria were ultimately included. The reported rates of depressive symptoms ranged from 4% to 43%. Of these studies, nine reported a statistically significant association, showcasing an adverse impact of depressive symptoms on medication adherence. The remaining nine did not confirm the above. This systematic review highlights the diverse body of research exploring depressive symptoms and medication adherence among individuals with hypertension. The review suggests a need for increased attention to self-care practices, particularly in relation to adherence to antihypertensive medication. However, it recommends the conduction of more robust longitudinal studies to comprehensively explore this relationship.

Efektivitas Mobile Health dan Supportive Education untuk Meningkatkan Kepatuhan Manajemen Perawatan Diri Pasien Hipertensi

This study aims to evaluate the effectiveness of mobile health interventions and supportive education in increasing self-care management compliance in hypertensive patients. The research method used is a literature review through databases, namely Scopus, Science Direct, Web of Science and Sage Journal. The results of 10 research articles report that interventions using mobile technology (m-health) and supportive educational interventions are very effective in increasing medication adherence in hypertensive patients. Conclusion, Interventions using mobile technology (m-health), combined with supportive educational interventions can be applied to increase self-care management compliance in hypertensive patients.
 
 Keywords: Supportive Education, Hypertension, Compliance, Mobile Health

Hypertension doctors' awareness and practice of medication adherence in hypertensive patients: a questionnaire-based survey.

Poor adherence to antihypertensive drugs is a major cause of unsatisfactory blood pressure control. Hypertension doctors play an integral role in improving medication adherence in hypertensive patients. Although most existing studies have recognized the status quo and influencing factors of medication adherence, little attention has been paid to hypertension doctors' awareness and practice in hypertension management. Therefore, in this study, we aimed to investigate hypertension doctors' awareness and practice of medication adherence in hypertensive patients. This is a cross-sectional survey. A self-reported questionnaire was developed and sent to hypertension doctors in Hunan province, China, between May 1, 2022 and July 1, 2022. Univariate and generalized linear models were used to identify the factors influencing hypertension doctors' awareness and practice. The correlation between awareness and practice was determined using Spearman's correlation coefficient. In total, 236 valid questionnaires were collected (valid response rate, 73.5%). Of the respondents, 44.1% were chief physicians and 64.4% were females. Approximately half of the respondents were ≥40 years old and had over 14 years of working experience. Most respondents (87.7%) did not have hypertension, but 54.2% had a family history of hypertension. The average awareness and practice scores were 29.8 ± 8.8 and 39.4 ± 7.1, respectively, out of 50, with higher scores indicating higher levels of awareness or practice. More hypertension consultations and more antihypertensive prescriptions issued were associated with better awareness and practice among respondents (ps < 0.05). Respondents with higher education and professional titles had higher awareness (ps < 0.05). Moreover, respondents with 6-13 years of work experience had better practice than those with <5 years of work experience (p = 0.017). There was a significant correlation between hypertension doctors' awareness and practice of medication adherence in hypertensive patients (R = 0.682, p < 0.001). These findings indicate that misconceptions persist in hypertension doctors' awareness and practice of patient medication adherence. Hypertension doctors lack sufficient and correct awareness and practice of medication adherence in hypertensive patients.

Add on digital cartoon video versus paper based counselling for medication adherence in hypertensive patients followed at a referral hospital in Yaoundé (Cameroon): a randomized control trial. (e-Adherence study)

Add on digital cartoon video versus paper based counselling for medication adherence in hypertensive patients followed at a referral hospital in Yaoundé (Cameroon): a randomized control trial. (e-Adherence study)

Concurrent Medication Adherence in Hypertensive Patients With High-Risk Comorbidities.

Hypertensive patients with high-risk comorbidities require medications for each condition, leading to greater burden. The number of chronic conditions can affect patients' concurrent medication adherence. We aimed to compare the characteristics of groups based on their concurrent medication adherence and investigate the association between the number of high-risk comorbidities and concurrent medication adherence for patients with hypertension and high-risk comorbidities. A secondary data analysis was performed with the 2018 Korea Health Panel Survey, including 2230 patients with hypertension and at least 1 high-risk comorbidity who were prescribed medications for at least 2 conditions. Using medication adherence for each condition, we identified 3 concurrent medication adherence groups: adherent, suboptimal, and nonadherent groups. Multinominal logistic regression was used to determine the association between the number of high-risk comorbidities and the concurrent medication adherence groups. Adherent, suboptimal, and nonadherent groups included 85%, 11%, and 4% of the patients, respectively. Whereas having more high-risk comorbidities was associated with belonging to the suboptimal group compared with the adherent group (adjusted odds ratio, 1.46), having fewer high-risk comorbidities was associated with belonging to the nonadherent group compared with the adherent group (adjusted odds ratio, 0.52). We identified 3 groups based on their concurrent medication adherence. Our results indicated that the relationship of the number of high-risk comorbidities with the concurrent medication adherence group was inconsistent.

Influence assessment of SARS-CoV outbreak in Riyadh on medication adherence in hypertensive patients in tertiary hospital

BackgroundThe impact of the COVID-19 outbreak on medication adherence has not been studied previously; this cross-sectional survey-based study on hypertensive patients was conducted to determine the impact of COVID-19 on medication adherence. MethodsA cross-sectional study conducted on hypertensive patients at King Abdulaziz Medical City (KAMC). 500 Patients were selected by a non-probability convenience sampling. The level of medication adherence was measured using a modified questionnaire after reviewing the literature. Data collection was done via interviews and the data was analyzed using the Statistical Package for Social Sciences (SPSS). ResultsThe 500 patients divided into 237 (47.4%) male and 263 (52.6%) female participants. 20.6% of the sample were smokers, while the majority of patients were non-smokers. Furthermore, 65% confirmed having other comorbidities. Almost 65% of the sample reported total adherence to their medications. The study considered those that missed more than 7 continuous days of medication to be non-adherent. As such, almost 5.8% of the sample reported non-adherence to their medications which was a noticeable decrease from previous studies. The variables that proved to have an association with medication adherence were level of education, awareness of blood pressure target, forgetfulness as a mental illness symptom, maintenance of social relationships, delays in medication refills and skips in medical appointments. ConclusionWhen compared to previous studies, this study revealed an increase in adherence rate, but there was no conclusive evidence of a correlation.

EVALUASI TINGKAT KEPATUHAN MINUM OBAT PASIEN HIPERTENSI DI PUSKESMAS KENJERAN MENGGUNAKAN METODE MMAS-8

Adherence is an important factor in controlling blood pressure in hypertensive patients. This study aimed to evaluate the level of medication adherence in hypertensive patients at the Kenjeran Health Center. The research method used was observational analysis with a cross-sectional design and evaluation through a questionnaire to measure the level of adherence and the MMAS-8 questionnaire to measure medication adherence. The results obtained for the level of medication adherence based on the MMAS-8 method showed that 52 patients (64%) were in the low MMAS-8 adherence category, 21 patients (26%) were in the moderate MMAS-8 adherence category, and 8 patients (10%) included in the high MMAS-8 compliance category. The conclusion of this study is that the level of adherence to medication use in hypertensive patients at the Kenjeran Health Center is at low adherence.

Chronic Care Model Based Nursing Interventions Improve Hypertension Patient’s Medication Compliance by Preventing Patients Forget and Fear

The goal of nursing intervention on chronic disease such as Hypertension is to improve the patient self-care, in which the Chronic care model could help to reach the best outcome. Research suggests the community, health workers, and regulations could improve the health. The purpose of this study was to apply nursing intervention based on chronic care model to medication adherence in hypertensive patients. This is quasi-experimental research used pre-post test control group design. 50 respondents of hypertension patients were recruited from Pucang Sewu, Pacar Keling and Tambak Rejo Surabaya Health Centres. The intervention was applicating nursing interventions based on the Chronic Care Model. The Mann Whitney U statistical analysis used to understand the effect of the intervention to the medication adherence in patients with hypertension. A total of 50 respondents who were divided into two groups, control and treatment, with each (n = 25). The distribution of characteristics in the two groups is homogeneous. Different test in the control group, there was no difference. The treatment group shown a significant difference in adherence before and after the intervention with p value 0.000 (p &lt;0.05). This study found the reason of disobedient patient to medication, which is forget and fear to the side effect. The patient and the health care agree frequent reminder could be the solution to this problem. Chronic Care Model based nursing interventions can improve medication adherence in hypertensive patients by encourage the health care system to frequently remind patients.

LEVEL OF MEDICATION ADHERENCE IN HYPERTENSIVE PATIENTS

Background: Hypertension (high blood pressure) is when the pressure in your blood vessels is too high (140/90 mmHg or higher). It is common but can be serious if not treated. A patient with hypertension who receives a treatment, implements a diet program, and carries out activities must comply with the recommendations of health workers.&#x0D; Objective: To find out the level of medication adherence in hypertensive patients at Selokerto Village.&#x0D; Method: This study was a quntitative study with a cross-sectional approach. The research sample was 100 people with hypertension at Selokerto Village and they were taken by total sampling method.&#x0D; Result: The results of this study were 63 (63%) respondents with a high level of medication adherence and 37 (37%) respondents with a moderate level of medication adherence.&#x0D; Conclusion: The level of medication adherence in Selokerto Village was dominantly good medication adherence.&#x0D; Recommendation: For further research, researchers are expected to examine the factors associated with medication adherence.

Effect of Social Support and Self Efficacy on Drug Taking Adherence in Hypertensive Patients: A Meta-Analysis

Background: Hypertension is a condition that causes a person to experience a drastic rise in blood pressure. Social support and self-efficacy are needed to improve skills, self-confidence and a sense of security for patients to be more compliant with taking medication. This study aimed to analyze the effect of social support and self-efficacy on medication adherence in hypertensive patients. Subjects and Method: This study is a meta-analysis using PICO, namely population: hypertensive patients; Intervention: good social support, good self-efficacy; Comparison: low social support, low self-efficacy; Result: medication adherence. The articles used in this study were obtained from two databases, namely PubMed and Google Scholar. Keywords in the article search “social cognitive theory (SCT)” AND “self efficacy“ AND ”social support “AND” hypertension” AND “medication adherence”, cross-sectional. The included article is full English with a cross-sectional study design for 2012–2022 and reports the adjusted odds ratio (aOR) in multivariate analysis. Selection of articles using the PRISMA flowchart. Article analysis using the Review Manager 5.3 application. Results: 7 articles with a cross-sectional study involving 708 people with hypertension from 2 continents namely Asia and Africa for systematic review and meta-analysis. The data collected showed that hypertensive patients with strong social support were twice as likely to adhere to medication as hypertensive patients with weak social support (aOR= 2.16; 95%CI= 1.82 to 2.57; p &lt;0.001), Hypertensive patients with self-efficacy Those who are strong are more likely to adhere to medication twice than hypertensive patients with weak self-efficacy (aOR= 2.11; 95% CI = 1.27 to 3.52; p &lt;0.004). Conclusion: Social support and self-efficacy improve medication adherence in hypertensive patients. Keywords: social support, self-efficacy, social cognitive theory, hypertension, medication adherence Correspondence: Sukma. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta, Central Java 57126, Indonesia. Email: sukmadenny1402@gmail.com. Mobile: +6281254428800. Journal of Epidemiology and Public Health (2023), 08(01): 138-149 https://doi.org/10.26911/jepublichealth.2023.08.01.12.

Self-Efficacy of Medication Adherence in Hypertensive Patients in Bandung Regency, Indonesia

Self-Efficacy of Medication Adherence in Hypertensive Patients in Bandung Regency, Indonesia

PENGARUH DUKUNGAN KELUARGA TERHADAP KEPATUHAN MINUM OBAT PASIEN HIPERTENSI DI PUSKESMAS MUARA WIS

One of the public health concerns is drug non-adherence. The main cause of poor hypertension control is noncompliance with antihypertensive medications. The elements that drive compliance behavior are numerous and complicated, with social support being one of them. Family support is critical in health care since it is through family support that a healthy family can be achieved. Family members can help by providing information about their sickness or reminding them to take their medications. The goal of this research was to identify the relationship between family support and medication adherence in hypertensive patients at Muara Wis Health Center, Kutai Kartanegara Regency, Province East Borneo. This study is descriptive correlational and uses a cross-sectional method, which involves measuring or observing at the same time and the same location. The participants in this study were 100 hypertensive patients of Muara Wis Health Center. The data in this study were analyzed using Spearman rank correlation. Based on the MMAS (Morisky Medication Adherence Scale) questionnaire, medication adherence in hypertensive patients at the Muara Wis Health Center had 52 percent low adherence, 29 percent moderate adherence, and 19 percent high adherence. According to pill count, low adherence patients was 51 percent, moderate adherence was 29 percent, and high adherence was 20 percent. Patients with hypertension who had poor family support were 54 percent, those who received moderate family support were 26 percent, and those who received strong family support were 20 percent. Hence, there is a significant relationship between family support and medication adherence in hypertensive patients of Muara Wis Health Center.

Adherence to prescribed antihypertensive medication among patients with depression in the United States

BackgroundHypertensive patients with depression have a higher mortality rate and a worse prognosis compared with hypertensive only. Depression may reduce medication adherence in hypertension patients.MethodsThis study includes respondents in the National Health and Nutritional Examination Survey (NHANES) database from 2005 to 2018 who had previously been diagnosed with hypertension. Medication adherence was defined as taking medication as recommended by a physician. The depressive state was assessed using the patient health questionnaire (PHQ)-9.ResultsNine thousand one hundred eighty-six respondents were included in the analysis. Medication adherence was associated with depression (odds ratio [OR]: 1.48, 95% confidence interval [CI]: 1.26 to1.75) and depression score (OR: 1.04 per each point increase, 1.03 to 1.05) in the unadjusted analyses. After adjusting for clinical and socioeconomic/demographic factors, there were significant statistical correlations between depression score and medication adherence (aOR: 1.02 per each point increase, 1.00 to 1.03, p < 0.05), but there was no significant statistical correlation between depression and medication adherence (p > 0.05). It was still statistically significant relationships between sex, age, body mass index (BMI), race, marital status, and health insurance with medication adherence after adjusted socioeconomic/demographic factors.ConclusionDepression was marginally associated with poor medication adherence in hypertensive patients, and the correlation increased with depression degree. Moreover, socioeconomic/demographic factors have an independent impact on medication adherence including sex, age, BMI, race, marital status, and health insurance.

Gambaran Penggunaan Pillbox Pasien Hipertensi dalam Rangka Meningkatkan Kepatuhan Minum Obat di Kecamatan Lubuk Kilangan

Hypertension is a chronic disease with long-term treatment. According to World Health Organization (WHO) data, only 36.8% of hypertensive patients take hypertension medication properly. Adherence is the most common problem in the treatment of hypertension. This adherence can be improved by providing counseling regarding the use of medicine boxes as a tool that can increase patient compliance in taking medicine. This community service activity aims to improve medication adherence in hypertension patients in Lubuk Kilangan District, Padang City. The counseling session was held among 35 participants. Based on sociodemographic data, it was found that there were differences in the number of female and male participants (80%: 20%), as well as the level of education and type of work (unemployment 94%) . Therefore, community service is expected to improve medication adherence in hypertensive patients (&gt;80%). If medication adherence has increased, it is hoped that the incidence of hypertension can be reduced.

To improve medication adherence in hypertensive patients: A cross section Study

Aim: To improve medication adherence in hypertensive patients.Methods and Materials: This cross-sectional observational research was conducted among participants with hypertension who had been on therapy for the previous 12 months were recruited for the trial after providing written informed permission. A full history was obtained, and the subjects were subjected to a thorough clinical evaluation, as well as counselling for lifestyle changes. The patients were given the MO risky Medication Adherence Scale-8 (MMAS-8) and WHO-QOL Brief questionnaires, and they were given time to complete them in a separate room away from the treating physician.Results: The average age of the patients was 53.98±10.78 years, the average number of medications taken per individual was 1.82±0.79, and 74% of the patients were using a combination of pharmaceuticals for hypertension. The mean MMAS-8 Score of 4.52±1.22 and the mean WHO-QOL Brief Scores. The mean duration of illness in Group 1 was substantially (p0.05) smaller than in Group 2 (4.41±2.52 years vs. 5.51±2.81 years), and the MMAS-8 scores in Group 1 were significantly (p<0.05) higher (4.81±1.42 vs. 3.79±0.76) — patients in Group 1 were more adherent to treatment than patients in Group 2. Group 1 had better scores in three domains: physical health (12.12±1.42 vs. 12.11±1.42), social connection (13.54±4.25 vs. 12.89±4.52), and environment (12.02±1.28 vs. 12.06±1.47), but Group 2 had higher scores in one domain: psychological (13.11±2.36 vs. 12.95±2.41). Because the surveys were only to be filled out by patients, there was a risk of interpretation bias based on the patients' comprehension.Conclusion: To summarise, patients had a poor adherence score, which was considerably lower in patients who were taking two or more drugs in combination or as a single component

Factors Related to Medication Adherence in Hypertensive Patients in the Iranian Population

Factors Related to Medication Adherence in Hypertensive Patients in the Iranian Population