This study aims to understand the content, methods and effective implementation strategies of humanistic education in medical colleges in Shandong Province, to construct a process model of humanistic education in medical colleges in Shandong Province, and finally to propose a management intervention plan. This study adopted a multiple case study method, and semi-structured interviews were conducted with 4 humanistic education teachers, 3 medical students and 3 managers from three medical colleges in Shandong Province through purposive sampling and snowballing methods. This study used the basic ideas of grounded theory to conduct thematic analysis of the interview data. This study conducted open coding, screened typical sentences from the interviewees' answers, extracted keywords from the typical sentences; then the keywords were classified and sorted to further extract relevant information such as the content, methods, and implementation strategies of humanistic education in higher medical colleges. The research results show that the humanities education in medical schools in Shandong Province has a certain foundation, but there are still some shortcomings. In addition, the study proposed four (4) concepts, namely: humanistic leadership in medical schools, strengthening humanistic guidance, strengthening the humanistic development of medical students, and cultivating and nurturing students' humanistic qualities. Furthermore, the findings also indicated the positive impact of empathy, communication skills, and cultural awareness, which highlights the importance of integrating humanities into medical education to develop well-rounded, compassionate healthcare professionals of the future.Based on the findings, a management intervention plan is hereby proposed.