Medical Affairs Research Articles

Medical Science Liaisons: A Guide for Advanced Practice Registered Nurses

Medical science liaisons (MSLs) are part of the field medical affairs (FMA) department of pharmaceutical companies and are scientific resources for advanced practice registered nurses (APRNs). Following strict regulations and antikickback statutes, MSLs operate differently from sales and engage in unbiased, nonpromotional scientific exchange to provide clinical resources to APRNs. They also collaborate with shareholders like professional organizations, clinical trial sites, and academic institutions. Understanding MSL engagement allows APRNs multiple avenues both externally and within the pharmaceutical industry to leverage their experience to enhance clinical practice.

Artificial Intelligence in Medical Affairs: A New Paradigm with Novel Opportunities.

The advent of artificial intelligence (AI) revolutionizes the ways of working in many areas of business and life science. In Medical Affairs (MA) departments of the pharmaceutical industry AI holds great potential for positively influencing the medical mission of identifying and addressing unmet medical needs and care gaps, and fostering solutions that improve the egalitarian and unbiased access of patients to treatments worldwide. Given the essential position of MA in corporate interactions with various healthcare stakeholders, AI offers broad possibilities to support strategic decision-making and to pioneer novel approaches in medical stakeholder interactions. By analyzing data derived from the healthcare environment and by streamlining operations in medical content generation, AI advances data-based prioritization and strategy execution. In this review, we discuss promising AI-based solutions in MA that support the effective use of heterogenous information from observations of the healthcare environment, the enhancement of medical education, and the analysis of real-world data. For a successful implementation of such solutions, specific considerations partly unique to healthcare must be taken care of, for example, transparency, data privacy, healthcare regulations, and in predictive applications, explainability.

Cultivating Excellence: Future-Proofing Medical Affairs with Tailored Talent Programs.

In today's rapidly growing healthcare landscape, the role of Medical Affairs within pharmaceutical companies has transitioned from a traditional support function into a strategic one. Amidst acute challenges such as evolving globalization, digitization, and healthcare trends, effective talent development and professional standards in Medical Affairs emerge as a pivotal cornerstone to future-proof pharmaceutical companies. This article explores strategies, perspectives, and best practices for enhancing talent development with medical or natural sciences background in the field of Medical Affairs. From the historical development of Medical Affairs, we cover current challenges and provide a comprehensive approach to talent development strategies of next-generation talents in Medical Affairs. Drawing upon current literature and personal experiences, we discuss various aspects relevant for designing targeted training programs, fostering interdisciplinary collaboration, and enhancing both technical and soft skills essential for success in Medical Affairs roles. Furthermore, we highlight the significance of company-internal rotational programs in exposing talents to different facets of Medical Affairs. We advocate for a flexible and individualized approach to talent development, allowing next-generation talents to pursue personal interests and contribute to innovative projects. Overall, this article offers practical recommendations for pharmaceutical companies aiming to optimize their local talent development initiatives in Medical Affairs and align them with the evolving needs of the healthcare landscape.

More than red tape: exploring complexity in medical device regulatory affairs.

This study investigates the complexity of regulatory affairs in the medical device industry, a critical factor influencing market access and patient care. Through qualitative research, we sought expert insights to understand the factors contributing to this complexity. The study involved semi-structured interviews with 28 professionals from medical device companies, specializing in various aspects of regulatory affairs. These interviews were analyzed using a mix of qualitative coding and natural language processing (NLP) techniques. The findings reveal key sources of complexity within the regulatory landscape, divided into five domains: (1) regulatory language complexity, (2) intricacies within the regulatory process, (3) global-level complexities, (4) database-related considerations, and (5) product-level issues. The participants highlighted the need for strategies to streamline regulatory compliance, enhance interactions between regulatory bodies and industry players, and develop adaptable frameworks for rapid technological advancements. Emphasizing interdisciplinary collaboration and increased transparency, the study concludes that these elements are vital for establishing coherent and effective regulatory procedures in the medical device sector.

Improved Nursing Workload by Introducing a Traceability System to Manage Medical Materials.

This paper reports a case study in which an improvement in nursing work was achieved through the introduction of a traceability system compatible with radio-frequency identification (RFID) and bar codes for the management of medical materials. In verifying the RFID-based system in an operating room, the work time was reduced to approximately one-tenth of that of barcode reading. In the catheterization laboratory, a system consisting of a cartel management system utilizing bar codes and an RFID-compatible inventory management cabinet was introduced. The system eliminates the need to cut and paste packages onto vouchers after the cases are completed and digitizes the data sent to the medical affairs department for secure billing. We are implementing this system at many facilities, and, in addition to improving the work of nurses, we are taking new steps to improve hospital management through data linkage.

Raising Awareness of Mistreatment Policies and Reporting Procedures Using a Novel Medical Student Mobile Application.

Reports of mistreatment are an important first step to improving medical students' learning environment. Students may not report mistreatment due to a lack of awareness of institutional policies, reporting procedures, or for fear of reprisal. We sought to determine if a medical school cross-platform mobile application (app) could be used to improve students' awareness of mistreatment policies and procedures. Participants in this intervention included Drexel University College of Medicine (DUCOM) medical students, faculty, and Student Affairs Deans. We created the DUCOMpass© app to make mistreatment policies and procedures more readily available and to ease mistreatment reporting for medical students. To determine the efficacy of the app at raising mistreatment awareness, we analyzed our institutional GraduationQuestionnaire data before and after the introduction of the app (from 2016 to 2023) as compared with the national average. We verified our students' self-reported data with app usage data. To our knowledge, this is the first instance of a medical school mobile app being implemented to successfully address medical student mistreatment awareness and reporting. We found that reaching students in a familiar and easily accessible mode(s) of communication is a catalyst for lasting change. Not applicable.

How Can General Managers Best Leverage Medical Affairs Now and in the Future?

General managers (GMs) play a crucial role as enterprise leaders of the country affiliate of multi-national pharmaceutical companies, balancing needs, objectives and governance across all local functions. One such function, Medical Affairs, has undergone a significant evolution from a support function into a strategic partner and in some organizations a strategic leader supported by the increasing complexity of medications and a shift to more specialized medicines. Although the function has progressed significantly, there is opportunity to elevate Medical Affairs to another level, with GMs and business unit directors (BUDs) recommending increased business acumen, strategic approach, innovation and project management as competencies that could be further cultivated. Examining the current trends in the industry, including the increasing complexity of innovative medicines and patient journeys, a higher burden of evidence for the reimbursement of medicines, innovative data generation opportunities, the changing stakeholder engagement expectations and the focus on corporate reputation, Medical Affairs is positioned as a key to assist in navigating the organization through these complexities. The GM can help to foster the evolving role of Medical Affairs, encouraging lateral moves for broader enterprise mindset, imparting a culture of shared governance responsibilities across functions to encourage innovative thinking and nurture upcoming leaders by investing in training to take advantage of the above trends and deliver best patient and organizational outcomes now and in the future.

Training needs and educational sources of European musculoskeletal specialists: learning outcomes of the IBSA International Academy – MSK Modules

Background: Building a meaningful training program for musculoskeletal (MSK) specialists is a major undertaking to improve the clinicians’ skills and ultimately patients’ outcome. The purpose of this study was to gather direct information from attendants of a training program called IBSA International Academy – MSK Modules on the perceived benefit of such initiative. Methods: The IBSA International Academy has been developed during 2021 by IBSA’s Global Medical Affairs department with the involvement and support of an international faculty composed by experts in the field that has become the scientific Board of the Academy. More than 100 specialists from several European countries attended one or more modules focused on ultrasound (US) and US-guided infiltration and were asked to answer (a) a short survey just after the modules were completed and (b) a more detailed survey several weeks after their return to daily practice. Results: A total of 114 specialists from 12 European countries attended the academy. The post-module evaluation form was completed by 94 (82.4%) and the follow-up survey by 30 (26.3%) participants. Response rate was highest for specialists from Nordic countries (50.0%) and lowest from Balkan countries (11.1%). The overall feedback of the participants to the academy was overwhelmingly positive both immediately and medium–long term after return to daily practice. About 57% of responders indicated mastering US and 30% indicated a better understanding of the anatomy as a key learning outcome of the academy. The added value of networking between peers and of direct contact with the experts in the faculty was mentioned by 77% and 53% respectively.

Blended e-learning and certification for medicines development professionals: results of a 7-year collaboration between King's College, London and the GMDP Academy, New York.

The field of Medicines Development faces a continuous need for educational evolution to match the interdisciplinary and global nature of the pharmaceutical industry. This paper discusses the outcomes of a 7-year collaboration between King's College London and the Global Medicines Development Professionals (GMDP) Academy, which aimed to address this need through a blended e-learning program. The collaboration developed a comprehensive curriculum based on the PharmaTrain syllabus, delivered through a combination of asynchronous and synchronous e-learning methods. The program targeted a diverse range of professionals serving in areas related to Medical Affairs. Over seven annual cohorts, 682 participants from eighty-six countries were enrolled in the program. The program's effectiveness was assessed using Kirkpatrick's model, showing elevated levels of satisfaction (over 4.0 on a five-point scale), suggesting significant gains in competence at the cognitive level and leveraged performance. Notably, 70% of responding alumni reported significant improvement in their functions, corroborated by 30% of their supervisors. The further long-term impact of the program on their respective organization has not been established. The GMDP Academy's program has significantly contributed to life-long learning in Medicines Development, addressing educational gaps and fostering interdisciplinary collaboration. Its success highlights the importance of continuous education in keeping pace with the industry's evolving demands and underscores the potential of blended learning in achieving educational objectives in pharmaceutical medicine.

Analysis Effect of Personnel Competence in Medicine and Health (BIDDOKKES) on Health Service Satisfaction in Southeast Sulawesi Regional Police

The aim of this research is to examine the influence of skills on the satisfaction of service personnel in the Medical and Health Affairs of the Southeast Sulawesi Regional Police Department. Analyzing the knowledge towards the satisfaction of service personnel in the Medical and Health Affairs of the Southeast Sulawesi Regional Police Department. Analyzing the social roles towards the satisfaction of service personnel in the Medical and Health Affairs of the Southeast Sulawesi Regional Police Department. Analyzing the self-image towards the satisfaction of service personnel in the Medical and Health Affairs of the Southeast Sulawesi Regional Police Department. Analyzing the attitudes towards the satisfaction of service personnel in the Medical and Health Affairs of the Southeast Sulawesi Regional Police Department. This research adopts a cross-sectional approach. The population in this study consists of 351 personnel. The results of this study indicate that skills significantly influence the satisfaction of service personnel in the Medical and Health Affairs of the Southeast Sulawesi Regional Police Department. Knowledge significantly influences the satisfaction of service personnel in the Medical and Health Affairs of the Southeast Sulawesi Regional Police Department. Social roles significantly influence the satisfaction of service personnel in the Medical and Health Affairs of the Southeast Sulawesi Regional Police Department. Self-image has no significant effect on service satisfaction for Medical and Health Personnel at the Southeast Sulawesi Regional Police. Attitudes significantly influence the satisfaction of service personnel in the Medical and Health Affairs of the Southeast Sulawesi Regional Police Department.

E065 Disagreement between patient and physician global assessment over time in psoriatic arthritis: insight into treatment priorities

Abstract Background/Aims The psoriatic arthritis (PsA) core domain set developed by the outcome measures in rheumatology working group includes musculoskeletal disease, fatigue, physical function, and structural damage, of which arthritis activity, pain, and fatigue were identified as essential by both patients (Pts) and physicians (Phs). Assessing agreement between Pt and Ph global assessments (GA) may provide valuable insight into differential importance of specific PsA manifestations to Pts vs Phs. Although previous studies have assessed Pt/Ph disagreement, they have not evaluated potential variation over time. This research sought to assess agreement of PtGA and PhGA through week (W) 24 and identify factors driving disagreement between PtGA and PhGA using pooled data (N = 1120) from the phase 3 DISCOVER (D)-1 & -2 studies of the fully human IL-23p19 subunit inhibitor (i), guselkumab (GUS). Methods Pts with active PsA despite standard therapies (D1: ≥3 swollen/tender joint counts [SJC/TJC], CRP ≥0.3 mg/dL, ∼30% with prior TNFi; D2: ≥5 SJC/TJC, CRP ≥0.6 mg/dL, biologic-naïve) were randomized 1:1:1 to GUS 100 mg every 4 weeks (Q4W); GUS 100 mg at W0, W4, Q8W; or placebo. Pt/Ph agreement was defined as a difference of -15<phga-ptgaPtGA) and PtGA exceeding PhGA by ≥ 15 (PtGA>PhGA) among pts with PtGA/PhGA disagreement were assessed with the same logistic regression model considering pt demographics, disease characteristics, and pt-reported outcomes (PROs). The effect of GUS on disease parameters identified as determinants of PtGA vs PhGA disagreement was assessed with repeated measures mixed models adjusting for treatment group, baseline (BL) levels, prior TNFi use, and BL DMARD use.</phga-ptga Results At BL, mean (SD) SJC=11.5 (7.4), TJC=20.6 (13.3), FACIT-Fatigue score=29.9 (10.0), PtGA=66.9 (19.9), and PhGA=64.8 (15.9) were consistent with moderate to high disease activity. Agreement between PtGA and PhGA was seen in most instances (61.2%); 23.2% of cases were characterized by PtGA>PhGA and 15.7% by PhGA>PtGA. The proportion of pts with PtGA>PhGA increased to 39.1% at W24, while that with PhGA>PtGA decreased to 11.2%. The main determinant of PtGA>PhGA was higher Pt Pain (all time points); additional factors included worse physical health-related quality of life at BL and worse fatigue at W24. Conversely, Phs emphasized objective disease measures, namely higher SJC (all time points) and TJC (W8 to W24), and elevated CRP (BL to W16). GUS treatment was associated with prompt and sustained significant improvements in all identified determinants, including those driving PtGA>PhGA. Conclusion PtGA and PhGA were aligned in most encounters. PtGA>PhGA disagreement was driven by pain, fatigue, and physical health being weighed more by Pts than Phs. These findings have important implications in shared decision making and highlight the need to prioritize treatments addressing the full spectrum of PsA symptoms, including PROs. Disclosure W. Tillett: Consultancies; AbbVie; Amgen; Eli Lilly; Janssen; MSD; Novartis; Pfizer and UCB. Member of speakers’ bureau; Abbvie; Amgen; Eli Lilly; Janssen; MSD; Novartis; Pfizer and UCB. Grants/research support; AbbVie; Amgen; Eli Lilly; Janssen and UCB. P. Rahman: Consultancies; AbbVie; Amgen; Bristol Myers Squibb; Celgene; Eli Lilly; Janssen; MSD; Novartis; Pfizer and UCB. Grants/research support; Janssen and Novartis. L.C. Coates: Consultancies; AbbVie; Amgen; Boehringer Inelheim; Bristol Myers Squibb; Celgene; Eli Lilly; Gilead; Galapagos; Janssen; Novartis; Pfizer and UCB. Member of speakers’ bureau; AbbVie; Amgen; Biogen; Celgene; Eli Lilly; Galapagos; Gilead; Janssen; Medac; Novartis; Pfizer and UCB. Grants/research support; AbbVie; Amgen; Celgene; Eli Lilly; Janssen; Novartis; Pfizer and UCB. P. Nash: Grants/research support; AbbVie; Boehringer Ingelheim; Bristol Myers Squibb; Celgene; Eli Lilly; Gilead; Janssen; Pfizer; Novartis; Roche; Sandoz; and Sun Pharmaceutical Industries. A. Deodhar: Consultancies; AbbVie; Amgen; Aurinia; Bristol Myers Squibb; Celgene; Eli Lilly; GlaxoSmithKline; Janssen; MoonLake; Novartis; Pfizer and UCB. Member of speakers’ bureau; AbbVie; Eli Lilly; Janssen; Novartis; Pfizer and UCB. Grants/research support; AbbVie; Eli Lilly; GlaxoSmithKline; Novartis; Pfizer and UCB. F. Nantel: Consultancies; Janssen. Shareholder/stock ownership; Johnson & Johnson. E. Rampakakis: Corporate appointments; Employee of JSS Medical Research. Consultancies; Janssen. L. Bessette: Consultancies; AbbVie; Amgen; Bristol Myers Squibb; Eli Lilly; Fresenius Kabi; Gilead; Janssen; MSD; Novartis; Pfizer; Sandoz; Sanofi; Teva and UCB. Member of speakers’ bureau; AbbVie; Amgen; Bristol Myers Squibb; Eli Lilly; Fresenius Kabi; Janssen; MSD; Novartis; Pfizer; Sandoz; Sanofi; Teva; and UCB. Grants/research support; AbbVie; Amgen; Bristol Myers Squibb; Celgene; Eli Lilly; Janssen; MSD; Novartis; Pfizer; Sanofi and UCB. M. Marrache: Corporate appointments; Employee of Janssen Inc. Toronto, Cananda. Shareholder/stock ownership; Johnson & Johnson. F. Lavie: Corporate appointments; Employee of Immunology Global Medical Affairs, Janssen Pharmaceutical Companies of Johnson & Johnson. Shareholder/stock ownership; Johnson & Johnson. M. Shawi: Corporate appointments; Employee of Immunology Global Medical Affairs, Janssen Pharmaceutical Companies of Johnson & Johnson. Shareholder/stock ownership; Johnson & Johnson.

Redefining the Role of Medical Affairs Professionals as Innovators and Leaders in Industry-Led Medical Education.

Medical affairs professionals are pivotal players at the intersection of medical innovation and practice in the pharmaceutical industry. They are uniquely positioned to translate complex medical knowledge into actionable insights for internal and external stakeholders. Industry-led continuing medical education (CME) programs, guided by these professionals, hold the potential to markedly improve clinicians' application of evidence-based medicine (EBM) in clinical settings, thereby elevating patient care outcomes. However, current CME techniques often overlook the integration of diverse disciplines such as educational theories, cognitive psychology, information mastery, and implementation science, which are important for effective real-time decision-making in patient care. This gap in integrating implementation science is vital, as it is key in ensuring that medical innovations are not just developed but also effectively implemented and efficiently utilized in clinical settings. In this opinion article, we aim to highlight the crucial yet often underrecognized role of medical affairs professionals in shaping robust and practical CME programs within the industry. We explore emerging trends and approaches in medical education and CME based on the principles of adult education. Additionally, we explore how medical affairs professionals can effectively drive the adoption of EBM in clinical practice. This exploration aims to provide insights into enhancing CME programs, with medical affairs professionals at the forefront of innovation and leadership in bridging gaps in clinical practice.

Survey on the Situation of Medical Departments in the Pharmaceutical Industry in Spain.

Medical departments have evolved from a position of support to one of strategic leadership. The number of tasks and the complexity of interactions in which they are involved is increasing. However, the spectrum of their activity in the sector differs significantly from one company to another. Therefore, the aim of this study was to describe their situation within the pharmaceutical industry, analyzing the positions, functions, and profiles of their professionals. This study consisted of an online survey containing 25 questions grouped into four blocks (structure, medical direction, training, and activities and responsibilities). Medical departments in the Spanish pharmaceutical industry of different sizes and scope were invited to participate. The survey took place in 2021, with a designated response period of three months. It is important to note that all responses collected during this time were treated as anonymous. Thirty companies participated. A total of 93.3% of respondents worked for an international laboratory, with a size of 0-5 or 11-20 people (20.7%). For 27.6% of the companies, the number of medical advisors per medical department was 1 or 4, with varying numbers of medical scientific liaisons (1, 6-10, and > 20). A total of 56.7%, 33.3%, and 6.7% indicated that the country manager, head of regional medical affairs, and head of global medical affairs, respectively, had a solid-line reporting relationship with the medical directorate. Medical directors were mostly graduates in medicine (86.2%) with a doctorate (34.5%), and medical managers were mainly graduates in medicine (77.8%) and pharmacy (66.7%). This study reveals that respondents predominantly work in internationally focused laboratories, with professionals ranging from experienced medical directors to managers with 6-20 years of experience, each with distinct roles.

Exploring the Value of Medical Affairs Learning Experiences for Pharmacy Students and Residents

The objective of this article is 3-fold: to strengthen the understanding of medical affairs (MA) among pharmacy professionals; to provide greater visibility into the value experienced by educators, learners, and the practice of pharmacy across the health care ecosystem when MA learning opportunities are available; and to provide a framework for organizations who seek to establish an MA experiential rotation. The authors collated information from published literature, anecdotal experience, and interviews with experiential education leaders from several colleges of pharmacy. As a result, the article summarizes the current perceptions of MA practice among educators and students and highlights how MA experiences may support pharmacy learners in the future.

Структурные изменения в управлении медицинским делом восточносибирских окраин как результат ревизионной поездки генерал-губернатора Н. Н. Муравьёва-Амурского

This article examines the transformations that followed the inspection of Governor General N. N. Muravyov in the entrusted territories. Against the backdrop of the global task of restructuring the administrative-territorial system, changes have occurred in the management of social issues, in particular, medical affairs. Thus, the simplified management system of the Yakut, Kamchatka, Transbaikal regions, providing for the independence of governors, contributed to the introduction of the positions of medical inspectors and the formation of a staff of medical officials. The most significant changes took place in the medical sphere of the Trans-Baikal region, where medical care for the military contingent began to form.

Social Media Impact on Traditional Journalism Content Change and Reader Behavior Analysis

Abstract With the rapid development of social media, the number of netizens using social media such as microblogging, WeChat, and forums is growing rapidly, and there are more and more channels to obtain news information. This study introduces “technological innovation” as the mediator variable, social media usage as the independent variable, traditional journalism content change, and reader behavior as the dependent variable, and age and political affiliation as the control variables to explore how social media plays its influential role. The survey study yielded a total of 896 valid data samples. Regression analysis using a PLS model was used to test the relevant hypotheses. The regression results show that without the introduction of the mediator variable “scientific and technological innovation”, social media has a significant effect on the content change of traditional news, and the R-squared explanation rate is 16.8%, which indicates that social media positively affects the content change of traditional news. Meanwhile, among the information content of social media, life and medical information (β=0.075, P<0.05) and current affairs and social information (β=0.112, P<0.001) positively affect the reader behavior of traditional journalism, which indicates that social media has a significant impact on influencing the reader behavior of traditional news. After the introduction of the “scientific and technological innovation” variable, the core value of the previous regression model decreases and becomes significant, indicating that scientific and technological innovation plays a mediating role in the above influence path.

Военно-медицинскому журналу Министерства обороны Российской Федерации – 200 лет!

January 2023 marked the 200th anniversary of the publication of the first issue of the Military Medical Journal, the oldest Russian periodical devoted to the consecration of medical issues related to both public health in general and military medicine in particular. The author of the idea and the active initiator of the foundation and publication of the «Military Medical Journal» was a military doctor, life surgeon of the Russian Imperial Court, organizer of military medical affairs in the Russian army, President of the Imperial Medical and Surgical Academy, Chief Military Medical Inspector of the Russian Army, acting privy Councilor, Baronet Yakov Vasilyevich Willie.

Strategic Medical Affairs Outsourcing: Pragmatic Solution In A Fast-Changing And Resource-Constrained World

This review explores the advantages of strategic medical affairs outsourcing and introduces 'Medical Affairs Consultation' as a pivotal concept. The pharmaceutical industry grapples with challenges such as regulatory complexity, cost pressures, and limited internal resources, requiring expertise in various domains. Medical affairs consultation empowers companies to navigate these hurdles, optimize costs, and expand geographically. The global market for medical affairs outsourcing is growing rapidly, presenting significant opportunities, particularly in the pharmaceutical sector. Outsourcing promotes agility and adaptability in this evolving healthcare landscape, while digital platforms enhance collaboration and information sharing on a global scale. However, careful risk evaluation and proactive management are essential for successful medical affairs outsourcing. Various outsourcing models cater to diverse organizational needs, allowing efficiency and effectiveness in specific functional areas. The future of outsourcing in India holds promise, driven by its skilled workforce, internet accessibility, and cost-efficiency.

Advancing medical affair capabilities and insight generation through machine learning techniques

BackgroundPharmaceutical companies are increasingly leveraging machine learning techniques to optimize healthcare research, drug development, and medical affairs activities. AI (artificial intelligence) tools such as chatbots, virtual digital assistants, and research tools have been explored to varying degrees of maturity in industries such as consumer goods or software technology. However, there continues to be untapped opportunities within the pharmaceutical industry to employ these technologies for enhanced engagement and education with healthcare professionals (HCPs). Pharmacists, situated at the crossroads of clinical sciences and innovation, have the potential to elevate their role and significance within the pharmaceutical industry by developing and leveraging such technologies.MethodsTo address this, the python-coded tool, Medical Information (MI) Data Uses For AI Semantic Analysis (MUFASA), utilizes state-of-the-art Sentence Transformer library, clustering, and visualization techniques. MUFASA harnesses unsolicited MI data with AI technology, improving efficiency and providing actionable medical affairs intelligence for targeted content delivery to HCPs.ResultsMUFASA optimizes medical affairs activities through its distinctive features: semantic search, cluster analysis, and visualization. Its proficiency in understanding inquiries, as demonstrated through 3D vector mapping and clustering tests, enhances the efficiency of MI and Medical Science Liaison (MSL) case handling. It proves invaluable in training new staff, bolstering response uniformity, and mitigating compliance risks. Leveraging the HDBSCAN algorithm, MUFASA's cluster analysis uncovers deep insights and discerns actionable themes from large inquiry data sets. The visualization graphs, generated from semantic searches, support evidence-based decisions by tracking the effectiveness of initiatives and monitoring trend shifts. Collectively, MUFASA enriches strategic decision-making, cultivates actionable insights, and bolsters healthcare professional engagement.ConclusionThere are numerous opportunities for innovation within the intersection of healthcare and data science. Pharmaceutical manufacturers, with one of their medical affairs responsibilities being the collection of unsolicited inquiries, particularly from HCPs, stand poised to leverage machine learning capabilities to optimize its processes. The abundance of data generated by the growing effort to use it in meaningful ways presents an opportunity for pharmaceutical companies to harness machine learning techniques.

Стратегия развития подготовки кадров в области медико-профилактического дела в Санкт-Петербурге на современном этапе

The development of the training system in the field of medical and preventive affairs in St. Petersburg was analyzed. The main tasks of staffing organizations and health care institutions, including the disinfection profile, are noted, which require immediate solution Keywords: licensing of disinfection activities, sanitary and epidemiological service, organizations and institutions of disinfection profile, medical organizations, secondary vocational education in the specialty «medical and preventive business».