Mechanisms Shaping Research Articles

The Impacts of Psychology and Neuroscience on Consumers’ Behaviour

The intersection of psychology and neuroscience has revolutionized our understanding of consumer behavior, offering profound insights into the cognitive and emotional processes that drive decision-making. This research explores the multifaceted impacts of psychological theories and neuroscientific advancements on consumer behavior, emphasizing how factors such as perception, memory, emotions, and neural mechanisms shape purchasing decisions. By integrating behavioral economics, cognitive neuroscience, and social psychology, the study highlights the role of implicit biases, heuristics, and neurochemical responses in influencing consumer preferences. Furthermore, the research examines the implications of neuromarketing techniques, such as brain imaging and biometric analysis, in predicting and shaping consumer behavior. Ethical considerations, including privacy concerns and the potential manipulation of consumer choices, are critically addressed to ensure responsible applications of these insights. By synthesizing theoretical models with empirical evidence, this study provides a comprehensive framework for leveraging psychology and neuroscience to enhance marketing strategies, improve consumer satisfaction, and foster ethical business practices.

Cosmopolitan nationalism as higher education policy? Converging and diverging discourses from China, Japan, and Korea

ABSTRACT This critical discourse analysis explores cosmopolitan nationalism as neoliberal reform within East Asian higher education (HE). Placing cosmopolitan nationalism within the Foucauldian genealogical oeuvre, we draw comparisons between Chinese, Japanese, and Korean HE policy to expand the theoretical basis of this emerging framework. Against this background, HE policy draws our gaze towards the tensions inherent to State-level demands for ‘enterprising’ units of human capital, or homo œconomicus. By producing graduates that are simultaneously internationalized and nationally-bound, HE pressures learners to incorporate the de-facto dispositions, skills, and credentials deemed necessary to the global market order. Here, policy maneuvers demonstrate a broadly analogous yet, unique predilection for nationalistic rhetoric during their resistance and accommodation of Western-led neoliberalism. Nonetheless, State responses to said hegemony demonstrate conflicting approaches to the knowledge economy and, for that matter, which citizens are deemed ‘worthy’ of the ‘right kind of’ education. Results indicate that, despite a shared cultural legacy, the socio-political realities of each HE provider engender, to varying degrees, friction between the intended and material outcomes of HE marketization. Thus, we seek to provide greater insight for scholars of educational markets to interpret the forces and mechanisms shaping neoliberal character-building, both regionally and in alternative contexts.

Sustained inequity: Examining how organizational mechanisms shape black women engineering faculty’s participation in entrepreneurial education programs.

Sustained inequity: Examining how organizational mechanisms shape black women engineering faculty’s participation in entrepreneurial education programs.

Unified bursting strategies in ectopic and endogenous even-skipped expression patterns

Transcription often occurs in bursts as gene promoters switch stochastically between active and inactive states. Enhancers can dictate transcriptional activity in animal development through the modulation of burst frequency, duration, or amplitude. Previous studies observed that different enhancers can achieve a wide range of transcriptional outputs through the same strategies of bursting control. For example, in Berrocal et al., 2020, we showed that despite responding to different transcription factors, all even-skipped enhancers increase transcription by upregulating burst frequency and amplitude while burst duration remains largely constant. These shared bursting strategies suggest that a unified molecular mechanism constraints how enhancers modulate transcriptional output. Alternatively, different enhancers could have converged on the same bursting control strategy because of natural selection favoring one of these particular strategies. To distinguish between these two scenarios, we compared transcriptional bursting between endogenous and ectopic gene expression patterns. Because enhancers act under different regulatory inputs in ectopic patterns, dissimilar bursting control strategies between endogenous and ectopic patterns would suggest that enhancers adapted their bursting strategies to their trans-regulatory environment. Here, we generated ectopic even-skipped transcription patterns in fruit fly embryos and discovered that bursting strategies remain consistent in endogenous and ectopic even-skipped expression. These results provide evidence for a unified molecular mechanism shaping even-skipped bursting strategies and serve as a starting point to uncover the realm of strategies employed by other enhancers.

Unified bursting strategies in ectopic and endogenous even-skipped expression patterns.

Transcription often occurs in bursts as gene promoters switch stochastically between active and inactive states. Enhancers can dictate transcriptional activity in animal development through the modulation of burst frequency, duration, or amplitude. Previous studies observed that different enhancers can achieve a wide range of transcriptional outputs through the same strategies of bursting control. For example, in Berrocal et al., 2020, we showed that despite responding to different transcription factors, all even-skipped enhancers increase transcription by upregulating burst frequency and amplitude while burst duration remains largely constant. These shared bursting strategies suggest that a unified molecular mechanism constraints how enhancers modulate transcriptional output. Alternatively, different enhancers could have converged on the same bursting control strategy because of natural selection favoring one of these particular strategies. To distinguish between these two scenarios, we compared transcriptional bursting between endogenous and ectopic gene expression patterns. Because enhancers act under different regulatory inputs in ectopic patterns, dissimilar bursting control strategies between endogenous and ectopic patterns would suggest that enhancers adapted their bursting strategies to their trans-regulatory environment. Here, we generated ectopic even-skipped transcription patterns in fruit fly embryos and discovered that bursting strategies remain consistent in endogenous and ectopic even-skipped expression. These results provide evidence for a unified molecular mechanism shaping even-skipped bursting strategies and serve as a starting point to uncover the realm of strategies employed by other enhancers.

Co to jest citizen science?

WHAT IS CITIZEN SCIENCE? A DISCUSSION ON THE ELEMENTS OF ONTOLOGY, EPISTEMOLOGY AND METHODOLOGY OF CS IN THE SOCIAL SCIENCES The primary goal of this article is to undertake a critical examination of the Citizen Science (CS) concept, with a specific focus on its comprehension, evolution, as well as its purported and observed role within the realm of social sciences. The authors formulate several research inquiries pertaining to: (1) the contemporary understanding of CS in science; (2) the mechanisms shaping CS as an increasingly recognised approach in scientific research; and (3) the feasibility of applying CS in research within social sciences disciplines. Methodologically, the analysis relies on an interdisciplinary literature review, further enriched by employing the method of critically deliberating with representatives across a broad spectrum of scientific disciplines, showcasing diverse European academic traditions. The derived conclusions shed light on prevalent narratives concerning the core of CS, the mapping of its practical implementation, and both the constraints and opportunities within the field of social sciences.

Key factors driving soil diazotrophic community assembly and nitrogenase activity in Qinghai-Tibet alpine meadows

Biological nitrogen (N) fixation by soil diazotrophs is the primary source of nitrogen for natural grasslands, especially at high altitudes such as alpine meadow ecosystems. However, the mechanisms shaping the compositions and assembly processes of diazotrophic communities, as well as soil nitrogenase activity in alpine meadows remain poorly understood. In this study, 241 soil samples were collected from alpine meadows on the Qinghai-Tibet Plateau to investigate the distribution patterns and driving factors of diazotrophic communities and nitrogenase activities. Our results showed that soil N fixation potential across all samples ranged from 28.8 to 110 nmol C2H4 g-1h-1, and Nitrospirillum and Bradyrhizobium were the most dominant diazotrophic genera. The composition and diversity of soil diazotrophic communities were mainly influenced by soil pH, and to a lesser extent by aridity index and mean annual precipitation. The abundance of nifH gene decreased linearly with soil pH, whereas the ɑ-diversity increased linearly with soil total phosphorus. Null model analysis indicated that deterministic processes governed diazotrophic community assembly, and more acidic soil conditions led to more phylogenetically clustered diazotrophic communities. Partial least squares path modeling and linear regression analyses identified diazotrophic community composition, followed by climatic factors, nifH gene abundance and total phosphorus, as the dominant regulators of soil N fixation potential in alpine meadows. Unexpectedly, soil N fixation potential was not closely related to dominant diazotrophic genera, diversity, or assembly, but highly related to the less abundant diazotrophs. This study provides a novel insight into the ecological mechanisms shaping soil biological nitrogen fixation in alpine meadow ecosystems.

The social forming of professionals’ adaptive performance: a sensemaking perspective

ABSTRACT Adaptive performance of professionals describes task achievement under conditions of novelty or uncertainty. Research shows that this type of performance can be trained, and that social interaction often plays an important role in it. This study sought to clarify that role, by posing the research question of how social interaction shapes professionals’ sensemaking in adaptive performance. Our conceptual model integrates two concepts from organisational studies, sensedemanding and sensebreaking, with the Data/Frame Model of Sensemaking from cognitive psychology. To test this model empirically, we carried out an explorative, qualitative study. Data collection took place by means of interviews and field observation at an intensive care unit of a Dutch hospital. The analysis revealed that sensedemanding and sensebreaking facilitate sensemaking of professionals by, enabling ‘switches’ between sensemaking cycles crucial for adaptive performance. Based on our findings, we propose that the integration of sensedemanding and sensebreaking in the D/F Model of Sensemaking contributes to our understanding of socio-cognitive mechanisms shaping (the development of) professionals’ adaptive performance.

Molecular Innovations Shaping Beak Morphology in Birds.

The beak, a pivotal evolutionary trait characterized by high morphological diversity and plasticity, has enabled birds to survive mass extinction events and subsequently radiate into diverse ecological niches worldwide. This remarkable ecological adaptability underscores the importance of uncovering the molecular mechanisms shaping avian beak morphology, particularly benefiting from the rapidly advancing archives of genomics and epigenomics. We review the latest advancements in understanding how genetic and epigenetic innovations control or regulate beak development and drive beak morphological adaptation and diversification over the past two decades. We conclude with several recommendations for future endeavors, expanding to more bird lineages, with a focus on beak shape and the lower beak, and conducting functional experiments. By directing research efforts toward these aspects and integrating advanced omics techniques, the complex molecular mechanisms involved in avian beak evolution and morphogenesis will be deeply interpreted.

Origami electronic membranes as highly shape-morphable mechanical and environmental sensing systems

This work introduces a concept of highly shape-morphable macro-scale origami electronic membranes based on the design and fabrication of flexible electronics and engineering origami. The origami electronic membranes can change shapes, provide multi-modal mechanical and environmental sensing capabilities in room and harsh temperatures, and/or switch functions by mechanical shape reconfiguration. This paper presents the materials, design, and fabrication methods for realizing six origami electronic membranes capable of reconfiguring planar or three-dimensional shapes based on the modified flasher, Kresling, Miura-ori, circular, letter, and Tachi-Miura origami patterns. They can be folded into small, stowed geometries and controllably deployed into larger areas or volumes to cover expanded spaces for spatial sensing, enabling significant shape adaptability for flexible electronics beyond simple stretching or bending. The mechanical and environmental sensing modalities include measuring motions, mechanical strains, temperatures, UV light, and humidity. The results reported here may expand the use of flexible electronics to applications that especially require aggressive shape transitions between a small, folded geometry and a large surface or volume such as deployable sensing systems for space explorations and accessing and monitoring highly confined locations.

A 3D modelling approach to measuring structural characteristics of bird nest interiors

Abstract Nests are considered extended phenotypes of animals with potentially serious fitness consequences for the survival of offspring. Therefore, nest characteristics may contain valuable information about the underlying ecological and evolutionary mechanisms shaping animal reproduction. However, we currently lack efficient tools to archive nests and measure their characteristics, particularly concerning enclosed nests. Here we developed a step‐by‐step protocol of a 3D modelling approach to measure structural characteristics of nest interiors using the enclosed, dome‐shaped nests of Asian house martins as a test system. We first created the replicas of nest interiors using polyurethane (‘physical replicas’), from which 3D models were constructured using Metashape software (‘digital replicas’). We then estimated the volume and entrance area size of the digital replicas of nest interior using Metashape. To verify that the digital replicas preserve the structural characteristics of the physical replicas, we measured the volume and entrance area size of the physical replicas with Archimedes' drainage method and ImageJ, respectively. We then compared the manual measurements of the physical replicas to the values estimated from digital replicas. The estimates on the interior volume and entrance area size of 50 Asian house martin nests were nearly identical between physical and digital replicas. These results verified that the digital replicas are as reliable as the physical replicas for measuring structural characteristics of nest interior. Our 3D modelling approach allows for easy archiving as digital replicas of nest interiors endure preservation over time much better than actual nest specimens. Furthermore, digital replicas can be shared via internet and analysed for different aspects of morphometrics at any time by anyone. Overall, this tool should facilitate research on the ecology and evolution of animals in relation to nest construction.

Whole-Genome Resequencing Reveals Polygenic Signatures of Directional and Balancing Selection on Alternative Migratory Life Histories.

Migration in animals and associated adaptations to contrasting environments are underpinned by complex genetic architecture. Here, we explore the genomic basis of facultative anadromy in brown trout (Salmo trutta), wherein some individuals migrate to sea while others remain resident in natal rivers, to better understand how alternative migratory tactics (AMTs) are maintained evolutionarily. To identify genomic variants associated with AMTs, we sequenced whole genomes for 194 individual trout from five anadromous-resident population pairs, situated above and below waterfalls, in five different Irish rivers. These waterfalls act as natural barriers to upstream migration and hence we predicted that loci underpinning AMTs should be under similar divergent selection across these replicate pairs. A sliding windows based analysis revealed a highly polygenic adaptive divergence between anadromous and resident populations, encompassing 329 differentiated genomic regions. These regions were associated with 292 genes involved in various processes crucial for AMTs, including energy homeostasis, reproduction, osmoregulation, immunity, circadian rhythm and neural function. Furthermore, examining patterns of diversity we were able to link specific genes and biological processes to putative AMT trait classes: migratory-propensity, migratory-lifestyle and residency. Importantly, AMT outlier regions possessed higher genetic diversity than the background genome, particularly in the anadromous group, suggesting balancing selection may play a role in maintaining genetic variation. Overall, the results from this study provide important insights into the genetic architecture of migration and the evolutionary mechanisms shaping genomic diversity within and across populations.

Linking Phylogeny and Morphology to Resource Assimilation Within Aquatic Assemblages

ABSTRACTNiche partitioning promotes species coexistence. Yet, it remains unclear how phylogeny and morphology influence the trophic niches of closely related aquatic species with shared feeding modes. Freshwater mussels (Family: Unionidae) are a group of filter‐feeding bivalves that are ideal for investigating mechanisms of niche partitioning. Particle size selection and patterns of ingestion are controlled by gill latero‐frontal cirri density (CD) and the number of cilia per cirrus (CC). We investigated trophic assimilation and niche area using stable isotope signatures (𝛿13C and 𝛿15N) and gill morphology with scanning‐electron microscopy for a diverse mussel assemblage from the Sipsey River, Alabama, USA. We predicted that (1) trophic niches and gill morphology would differ within and among species across sites; (2) co‐occurring species would partition food resources; (3) greater phylogenetic distances among species would result in increased trophic dissimilarity; (4) more CC and higher CD would result in a narrower trophic niche area, or more constrained range of food items assimilated. We found that (1) species identity and site influenced gill morphology and stable isotope signatures but that the trophic niche area of a species was only affected by species identity; (2) the average proportion of niche area overlap between co‐occurring species was low across sites (0.04 to 0.18); (3) trophic dissimilarity among species increased with phylogenetic distance; (4) CD but not the number of CC negatively related to trophic niche area. Our results indicate that gill morphology and evolutionary history are likely key factors governing the trophic niches of mussels. In addition, intraspecific variation in gill morphology across sites may either reflect a phenotypic response to differences in local resource availability or suggest that other mechanisms shape particle selection. Examining the interplay among the trophic niche, phylogeny, and morphology among functionally similar species further informs our understanding of the mechanisms facilitating their coexistence.

Effect of Structural Configurations on Mechanical and Shape Recovery Properties of NiTi Triply Periodic Minimal Surface Porous Structures

Based on the advantages of triply periodic minimal surface (TPMS) porous structures, extensive research on NiTi shape memory alloy TPMS scaffolds has been conducted. However, the current reports about TPMS porous structures highly rely on the implicit equation, which limited the design flexibility. In this work, novel shell-based TPMS structures were designed and fabricated by laser powder bed fusion. The comparisons of manufacturability, mechanical properties, and shape recovery responses between traditional solid-based and novel shell-based TPMS structures were evaluated. Results indicated that the shell-based TPMS porous structures possessed larger Young’s moduli and higher compressive strengths. Specifically, Diamond shell structure possessed the highest Young’s moduli of 605.8±24.5 MPa, while Gyroid shell structure possessed the highest compressive strength of 43.90±3.32 MPa. In addition, because of the larger specific surface area, higher critical stress to induce martensite transformation, and lower austenite finish temperature, the Diamond shell porous structure exhibited much higher shape recovery performance (only 0.1% residual strain left at pre-strains of 6%) than other porous structures. These results substantially uncover the effects of structural topology on the mechanical properties and shape recovery responses of NiTi shape memory alloy scaffolds, and confirm the effectiveness of this novel structural design method. This research can provide guidance for the structural design application of NiTi porous scaffolds in bone implants.

A quantitative analysis of bestrophin 1 cellular localization in mouse cerebral cortex.

Calcium-activated ligand-gated chloride channels, beyond their role in maintaining anion homeostasis, modulate neuronal excitability by facilitating nonvesicular neurotransmitter release. BEST1, a key member of this family, is permeable to γ-aminobutyric acid (GABA) and glutamate. While astrocytic BEST1 is well-studied and known to regulate neurotransmitter levels, its distribution and role in other brain cell types remain unclear. This study aimed to reassess the localization of BEST1 in the mouse cerebral cortex. We examined the localization and distribution of BEST1 in the mouse parietal cortex using light microscopy, confocal double-labeling with markers for astrocytes, neurons, microglia, and oligodendrocyte precursor cells, and 3D reconstruction techniques. In the cerebral cortex, BEST1 is more broadly distributed than previously thought. Neurons are the second most abundant BEST1+ cell type in the cerebral cortex, following astrocytes. BEST1 is diffusely expressed in neuronal somatic and neuropilar domains and is present at glutamatergic and GABAergic terminals, with a prevalence at GABAergic terminals. We also confirmed that BEST1 is expressed in cortical microglia and identified it in oligodendrocyte precursor cells, albeit to a lesser extent. Together, these findings suggest that BEST1's role in controlling neurotransmission may extend beyond astrocytes to include other brain cells. Understanding BEST1's function in these cells could offer new insights into the molecular mechanisms shaping cortical circuitry. Further research is needed to clarify the diverse roles of BEST1 in both normal and pathophysiological conditions.

Tailoring smart hydrogels through manipulation of heterogeneous subdomains

The mechanical interactions among integrated cellular structures in soft tissues dictate the mechanical behaviors and morphogenetic deformations observed in living organisms. However, replicating these multifaceted attributes in synthetic soft materials remains a challenge. In this work, we develop a smart hydrogel system featuring engineered stiff cellular patterns that induce strain-driven heterogeneous subdomains within the hydrogel film. These subdomains arise from the distinct mechanical responses of the pattern and film domains under applied mechanical forces. Unlike previous studies that incorporate reinforced inclusions into soft matrices to tailor material properties, our method manipulates the localization, integration, and interaction of these subdomain building blocks within the soft film. This enables extensive tuning of both local and global behaviors. Notably, we introduce a subdomain-interface mechanism that allows for the concurrent customization and decoupling of mechanical properties and shape transformations within a single material system—an achievement rarely accomplished with current synthetic soft materials. Additionally, our use of in-situ imaging characterizations, including full-field strain mapping via digital imaging correlation and reciprocal-space patterns through fast Fourier transform analysis of real-space pattern domains, provides rapid real-time monitoring tools to uncover the underlying principles governing tailored multiscale heterogeneities and intricate behaviors.

Synthesis of a gallic acid-based self-healing waterborne polyurethane with a thermo-responsive dynamic phenol-carbamate network for enhanced mechanical strength, antimicrobial activity, and shape memory properties

To expedite the advancement of multifunctional next-generation smart materials, it is imperative to create polymers derived from renewable, green bio-based resources. This paper presents a direct synthesis of thermo-responsive aqueous polyurethanes by combining gallic acid (GA) with isocyanate groups to form a dynamic phenol-carbamate crosslinked network and the incorporation of the metal-organic framework Cu-MOF-2 for synergistic effects. The resulting GA-based polyurethane (MOF-GWPU) exhibits excellent thermal stability and mechanical properties, achieving an ideal balance between mechanical strength and self-healing efficiency. The MOF-GWPU film demonstrates strong antimicrobial efficacy against Escherichia coli and Staphylococcus aureus, highlighting its exceptional antibacterial performance. The thermo-responsive dynamic covalent bonds enable the MOF-GWPU film to rapidly revert from a temporary shape back to its original form. Post-processing experiments further indicate that the crosslinked GA-PU polymer can be efficiently recycled through solution casting and hot-pressing techniques. This design offers a novel approach and valuable insights for advancing the development of multifunctional smart polymers derived from bio-based resources.

Nanovibrational Stimulation of Escherichia coli Mitigates Surface Adhesion by Altering Cell Membrane Potential.

Mechanical forces shape living matter from the macro- to the microscale as both eukaryotic and prokaryotic cells are force wielders and sensors. However, whereas such forces have been used to control mechanically dependent behaviors in mammalian cells, we lack the same level of understanding in bacteria. Surface adhesion, the initial stages of biofilm formation and surface biofouling, is a mechanically dependent process, which makes it an ideal target for mechano-control. In this study, we employed nanometer surface vibrations to mechanically stimulate bacteria and investigate their effect on adhesion. We discovered that vibrational stimulation at the nanoscale consistently reduces surface adhesion by altering cell membrane potential. Our findings identify a link between bacteria electrophysiology and surface adhesion and provide evidence that the nanometric mechanical "tickling" of bacteria can inhibit surface adhesion.

Comparative Genomics of the World's Smallest Mammals Reveals Links to Echolocation, Metabolism, and Body Size Plasticity.

Originating 30 million years ago, shrews (Soricidae) have diversified into around 400 species worldwide. Shrews display a wide array of adaptations, with some species having developed distinctive traits such as echolocation, underwater diving, and venomous saliva. Accordingly, these tiny insectivores are ideal to study the genomic mechanisms of evolution and adaptation. We conducted a comparative genomic analysis of four shrew species and 16 other mammals to identify genomic variations unique to shrews. Using two existing shrew genomes and two de novo assemblies for the maritime (Sorex maritimensis) and smoky (Sorex fumeus) shrews, we identified mutations in conserved regions of the genomes, also known as accelerated regions, gene families that underwent significant expansion, and positively selected genes. Our analyses unveiled shrew-specific genomic variants in genes associated with the nervous, metabolic, and auditory systems, which can be linked to unique traits in shrews. Notably, genes suggested to be under convergent evolution in echolocating mammals exhibited accelerated regions in shrews, and pathways linked to putative body size plasticity were detected. These findings provide insight into the evolutionary mechanisms shaping shrew species, shedding light on their adaptation and divergence over time.

Females drive postmating reproductive trait evolution across Drosophila species, but not via remating rate.

While traits that contribute to premating sexual interactions are known to be wildly diverse, much less is known about the diversity of postmating (especially female) reproductive traits and the mechanisms shaping this diversity. To assess the rate, pattern, and potential drivers of postmating reproductive trait evolution, we analyzed male and female traits across up to 30 Drosophila species within a phylogenetic comparative framework. In addition to postmating reproductive morphology (e.g., sperm length, reproductive tract length and mass), we also quantified mating behaviors including female remating rate-a common proxy for the strength of postmating sexual selection. We found evidence for strong coevolution between male and female postmating traits (specifically sperm length and sperm storage organ size). However, remating rate was not associated with the rate of evolution or exaggeration of either male or female postmating reproductive morphology, once phylogenetic relatedness was accounted for. We infer that female-mediated and intersexual selection predominantly drive the evolution of our postmating morphological traits, including via divergent male and female interests in controlling paternity. In comparison, remating rate has a complex and likely secondary role in shaping this evolution, in part because this trait can be both a driver and a product of postmating selection.